Queering disasters: on the need to account for LGBTI experiences in natural disaster contexts

This article seeks a queering of research and policy in relation to natural disasters, their human impacts, management and response. The human impacts of natural disasters vary across different social groups. We contend that one group largely absent from scholarly and policy agendas is sexual and gender minorities, or lesbian, gay, bisexual, transgender/transsexual and intersex (LGBTI) populations. To demonstrate that these minorities have particular experiences that need to be addressed, we critically review five case studies that comprise the limited scholarly and policy research on LGBTI populations in disasters to date. Building on this, we offer some specific ways forward for queer disaster research that accounts for the vulnerabilities, needs and resilient capacities of LGBTI populations. In doing so, we recognise and urge researchers, policy-makers and aid agencies to acknowledge that LGBTI populations are not homogeneous and have different needs wrought by intersections of socio-economic resources, gender, race/ethnicity, age and regional or national location.Australian Research Council-DP130102658,DP130100877 University of Western Sydne

'The greatest loss was a loss of our history': natural disasters, marginalised identities and sites of memory

This paper examines intersections between space, materiality, memory and identity in relation to lesbian and gay experiences of recent disasters in Australia. Drawing on interviews with lesbians and gay men in two disaster sites, the paper argues that disaster impacts may include the loss of sites of memory that inform and underpin the formation and maintenance of marginalised identities. We explore the ways in which social marginality is experienced by sexual minorities during disasters as a result of threats to sites of lesbian and gay memory. The paper contributes to scholarship in geographies of memory by investigating the impacts of disasters on how memory is spatially located and experienced.Australian Research Council-DP13010265

Problems and possibilities on the margins: LGBT experiences in the 2011 Queensland floods

Vulnerability to disasters is not inherent to particular social groups but results from existing marginality. Marginalisation from social, political and economic resources and recognition underpins vulnerability and impedes recovery. Yet concurrently, disasters can reveal the resilient capacities of some marginal groups, who often develop specific means of coping with marginality. This article applies these perspectives to the experiences of LGBT (lesbian, gay, bisexual, trans) people during the 2011 disaster in Queensland, Australia, which resulted from catastrophic flooding of Brisbane and South-East Queensland. The findings come from a survey conducted by the Queensland Association for Healthy Communities (QAHC) a year after the floods, which sought to understand LGBT experiences, resources and needs. An agreement was established between QAHC and university researchers to facilitate data analysis. This article analyses some key findings using the concept of marginality to understand both vulnerability and resilience. This framework helps grasp the particular issues facing LGBT people. The data reveal vulnerability due to social and political marginality, including discrimination and inhibited access to assistance, but simultaneously examples of resilience borne by self-reliance and coping strategies developed in a context of marginality. Understanding LGBT marginality, vulnerability and resilience helps contribute to inclusive and effective disaster preparation, response and recovery.Australian Research Council-DP13010265

Listening and learning: giving voice to trans experiences of disasters

This article gives voice to trans experiences of disasters, investigating their specific vulnerabilities and resilient capacities. We draw on findings from a project on lesbian, gay, bisexual and trans (LGBT) experiences of recent Australian and New Zealand disasters. We present and analyse trans voices from a survey conducted across multiple case study sites and insights from interview data with a trans person who experienced the 2011 Brisbane floods. Conceptually, to provide a robust understanding of trans experiences of disasters, we bring socially sensitive disaster studies into conversation with trans geographies. Disaster studies have begun to examine LGBT experiences, with some suggestion that trans people are most vulnerable. We advance this work by focusing on trans lives. Trans geographies, in turn, underline the importance of space, place and the body in understanding trans lives, and the need to examine the lived reality of trans people’s everyday geographies rather than embodiment as an abstract concept. Applying these insights to the trans voices in our project, we examine four themes that highlight impediments to and possibilities for trans-inclusive disaster planning: apprehension with emergency services and support; concerns about home and displacement; anxiety about compromising the trans body; and the potential of trans and queer interpersonal networks for capacity building. We offer suggestions for trans-inclusive disaster planning and preparedness, and indicate how the insights from trans experience can enrich disaster planning and preparedness for wider social groups.Australian Research Council-DP13010265

A new deep SCUBA survey of gravitationally lensing clusters

We have conducted a new deep SCUBA survey, which has targetted 12 lensing galaxy clusters and one blank field. In this survey we have detected several sub-mJy sources after correcting for the gravitational lensing by the intervening clusters. We here present the preliminary results and point out two highlights.Comment: 4 pages, 2 figures, "Multiwavelength Cosmology" Mykonos, June 2003, conference proceeding

BRAIN Α-TOCOPHEROL CONCENTRATION IS INVERSELY ASSOCIATED WITH NEUROFIBRILLARY TANGLE COUNTS IN BRAIN REGIONS AFFECTED IN EARLIER BRAAK STAGES: A CROSS-SECTIONAL FINDING IN THE OLDEST OLD

Objectives: Higher vitamin E status has been associated with lower risk of Alzheimer’s disease (AD). However, evidence of the association of vitamin E concentration in neural tissue with AD pathologies is limited. Design: The cross-sectional relationship between the human brain concentrations of α- and γ-tocopherol and the severity of AD pathologies – neurofibrillary tangle (NFT) and neuritic plaque (NP) – was investigated. Setting & Participants: Brains from 43 centenarians (≥ 98 years at death) enrolled in the Phase III of the Georgia Centenarian Study were collected at autopsy. Measurements: Brain α- and γ-tocopherol concentrations (previously reported) were averaged from frontal, temporal, and occipital cortices. NP and NFT counts (previously reported) were assessed in frontal, temporal, parietal, entorhinal cortices, amygdala, hippocampus, and subiculum. NFT topological progression was assessed using Braak staging. Multiple linear regression was performed to assess the relationship between tocopherol concentrations and NP or NFT counts, with and without adjustment for covariates. Results: Brain α-tocopherol concentrations were inversely associated with NFT but not NP counts in amygdala (β = -2.67, 95% CI [-4.57, -0.79]), entorhinal cortex (β = -2.01, 95% CI [-3.72, -0.30]), hippocampus (β = -2.23, 95% CI [-3.82, -0.64]), and subiculum (β = -2.52, 95% CI [-4.42, -0.62]) where NFT present earlier in its topological progression, but not in neocortices. Subjects with Braak III-IV had lower α-tocopherol (median = 69,622 pmol/g, IQR = 54,389-72,155 pmol/g) than those with Braak I-II (median = 72,108 pmol/g, IQR = 64,056-82,430 pmol/g), but the difference was of borderline significance (p = 0.063). γ-Tocopherol concentrations were not associated with either NFT or NP counts in any brain regions assessed. Conclusions: Higher brain α-tocopherol level is specifically associated with lower NFT counts in brain structures affected in earlier Braak stages. Our findings emphasize the possible importance of α-tocopherol intervention timing in tauopathy progression and warrant future clinical trials

In depth analysis of kinase cross screening data to identify CaMKK2 inhibitory scaffolds

The calcium/calmodulin‐dependent protein kinase kinase 2 (CAMKK2) activates CAMK1, CAMK4, AMPK, and AKT, leading to numerous physiological responses. The deregulation of CAMKK2 is linked to several diseases, suggesting the utility of CAMKK2 inhibitors for oncological, metabolic and inflammatory indications. In this work, we demonstrate that STO‐609, frequently described as a selective inhibitor for CAMKK2, potently inhibits a significant number of other kinases. Through an analysis of literature and public databases, we have identified other potent CAMKK2 inhibitors and verified their activities in differential scanning fluorimetry and enzyme inhibition assays. These inhibitors are potential starting points for the development of selective CAMKK2 inhibitors and will lead to tools that delineate the roles of this kinase in disease biology.252CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO - CNPQFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESP465651/2014-32013/50724-5; 2014/50897-0; 2019/14275-

Active Galaxies in the UV

In this article we present different aspects of AGN studies demonstrating the importance of the UV spectral range. Most important diagnostic lines for studying the general physical conditions as well as the metalicities in the central broad line region in AGN are emitted in the UV. The UV/FUV continuum in AGN excites not only the emission lines in the immediate surrounding but it is responsible for the ionization of the intergalactic medium in the early stages of the universe. Variability studies of the emission line profiles of AGN in the UV give us information on the structure and kinematics of the immediate surrounding of the central supermassive black hole as well as on its mass itself.Comment: 29 pages, 13 figures, Ap&SS in pres