One-particle inclusive CP asymmetries

One-particle inclusive CP asymmetries in the decays of the type B -> D(*) X are considered in the framework of a QCD based method to calculate the rates for one-particle inclusive decays.Comment: Latex, 13 pages, 6 figures (eps). Analytical and numerical results unchanged, extended discussion of model assumptions and systematic uncertainties. Version to be published in Phys. Rev. D 62, 0960xx. Additional transparencies are available via the WWW at http://www-ttp.physik.uni-karlsruhe.de/Slides

Recovery oriented mental health nursing: a pilot Intervention study

Based on previous studies that have been focusing on current practices in mental health nursing and the on-going development in mental health practice towards a more recovery-oriented approach this pilot intervention study focuses on improving mental health nursing practice through providing specific training sessions for nurses and the implementation of goal-oriented care in close collaboration with service users. Results are measured within a pre- and post-test design among health professionals and service users. The presentation will contain an introduction of the study protocol, an experience report and hopefully some initial results of the study

Towards a FPGA-controlled deep phase modulation interferometer

Deep phase modulation interferometry was proposed as a method to enhance homodyne interferometers to work over many fringes. In this scheme, a sinusoidal phase modulation is applied in one arm while the demodulation takes place as a post-processing step. In this contribution we report on the development to implement this scheme in a fiber coupled interferometer controlled by means of a FPGA, which includes a LEON3 soft-core processor. The latter acts as a CPU and executes a custom made application to communicate with a host PC. In contrast to usual FPGA-based designs, this implementation allows a real-time fine tuning of the parameters involved in the setup, from the control to the post-processing parameters.Comment: Proceedings of the X LISA Symposium, Gainesville, May 18-23, 201

Sequence Dependence of Self-Interacting Random Chains

We study the thermodynamic behavior of the random chain model proposed by Iori, Marinari and Parisi, and how this depends on the actual sequence of interactions along the chain. The properties of randomly chosen sequences are compared to those of designed ones, obtained through a simulated annealing procedure in sequence space. We show that the transition to the folded phase takes place at a smaller strength of the quenched disorder for designed sequences. As a result, folding can be relatively fast for these sequences.Comment: 14 pages, uuencoded compressed postscript fil

Retarded Learning: Rigorous Results from Statistical Mechanics

We study learning of probability distributions characterized by an unknown symmetry direction. Based on an entropic performance measure and the variational method of statistical mechanics we develop exact upper and lower bounds on the scaled critical number of examples below which learning of the direction is impossible. The asymptotic tightness of the bounds suggests an asymptotically optimal method for learning nonsmooth distributions.Comment: 8 pages, 1 figur

Transduction of artificial transcriptional regulatory proteins into human cells

Protein transduction (PT) is a method for delivering proteins into mammalian cells. PT is accomplished by linking a small peptide tag—called a PT domain (PTD)—to a protein of interest, which generates a functional fusion protein that can penetrate efficiently into mammalian cells. In order to study the functions of a transcription factor (TF) of interest, expression plasmids that encode the TF often are transfected into mammalian cells. However, the efficiency of DNA transfection is highly variable among different cell types and is usually very low in primary cells, stem cells and tumor cells. Zinc-finger transcription factors (ZF-TFs) can be tailor-made to target almost any gene in the human genome. However, the extremely low efficiency of DNA transfection into cancer cells, both in vivo and in vitro, limits the utility of ZF-TFs. Here, we report on an artificial ZF-TF that has been fused to a well-characterized PTD from the human immunodeficiency virus-1 (HIV-1) transcriptional activator protein, Tat. This ZF-TF targeted the endogenous promoter of the human VEGF-A gene. The PTD-attached ZF-TF was delivered efficiently into human cells in vitro. In addition, the VEGF-A-specific transcriptional repressor retarded the growth rate of tumor cells in a mouse xenograft experiment

Reciprocal Damon-Eshbach-type spin wave excitation in a magnonic crystal due to tunable magnetic symmetry

We report spin-wave (SW) propagation in a one-dimensional magnonic crystal (MC) explored by all electrical spectroscopy. The MC consists of a periodic array of 255 nm wide permalloy nanowires with a small edge-to-edge separation of 45 nm. Provoking antiparallel alignment of the magnetization of neighboring nanowires, we unexpectedly find reciprocal excitation of DamonEshbach type SWs. The characteristics are in contrast to ferromagnetic thin films and controlled via, both, the external magnetic field and magnetic states. The observed reciprocal excitation is a metamaterial property for SWs and attributed to the peculiar magnetic symmetry of the artificially tailored magnetic material. The findings offer great perspectives for nanoscale SW interference devices. Spectroscopy performed on periodic arrays of bistable ferromagnetic nanowires has evidenced magnonic crystal (MC) behavior reflecting a man-made band structure for spin waves (SWs). 1,2 Periodic nanowires of identical width have recently been shown to form a special class of artificial crystal offering unprecedented functionality via reprogrammed band structures. Different magnetic states such as ferromagnetic order (FMO) and antiferromagnetic order (AFO) allowed one to redefine the unit cell and periodicity of the lattice in one-andthe-same one-dimensional (1D) MC. 3 At the same time, thin films and magnonic waveguides from yttrium iron garnet and Ni 80 Fe 20 have been shown to exhibit non-reciprocal SW characteristics when Damon-Eshbach-type (DE) spin waves were excited by microwave antenna. 4-8 For DE modes, the wave vector k is perpendicular to the magnetization M. Spin waves travelling in opposite directions had markedly different precessional amplitudes. For MCs, this issue has not yet been addressed in detail 9,10 though reciprocity is of special interest for magneto-photonics 11 and advanced applications, such as reprogrammable filters and logic devices based on SWs. In this paper, we report SWs transmitted through a 1D array of bistable permalloy (Ni 80 Fe 20 ) nanowires [ We explain this behavior considering the distinct magnetic symmetry of the artificial crystal, provoking a metamaterial property not found for the natural material. Our findings ar

Design and construction of an optical test bed for LISA imaging systems and tilt-to-length coupling

The laser interferometer space antenna (LISA) is a future space-based interferometric gravitational-wave detector consisting of three spacecraft in a triangular configuration. The interferometric measurements of path length changes between satellites will be performed on optical benches in the satellites. Angular misalignments of the interfering beams couple into the length measurement and represent a significant noise source. Imaging systems will be used to reduce this tilt-to-length coupling. We designed and constructed an optical test bed to experimentally investigate tilt-to-length coupling. It consists of two separate structures, a minimal optical bench and a telescope simulator. The minimal optical bench comprises the science interferometer where the local laser is interfered with light from a remote spacecraft. In our experiment, a simulated version of this received beam is generated on the telescope simulator. The telescope simulator provides a tilting beam, a reference interferometer and an additional static beam as a phase reference. The tilting beam can either be a flat-top beam or a Gaussian beam. We avoid tilt-to-length coupling in the reference interferometer by using a small photo diode placed at an image of the beam rotation point. We show that the test bed is operational with an initial measurement of tilt-to-length coupling without imaging systems. Furthermore, we show the design of two different imaging systems whose performance will be investigated in future experiments

Experimental Demonstration of Reduced Tilt-to-length Coupling by Using Imaging Systems in Precision Interferometers

Angular misalignment of one of the interfering beams in laser interferometers can couple into the interferometric length measurement and is called tilt-to-length (TTL) coupling in the following. In the noise budget of the planned space-based gravitational-wave detector evolved Laser Interferometer Space Antenna (eLISA) [1, 2] TTL coupling is the second largest noise source after shot noise [3