821 research outputs found

    PaperMaker: validation of biomedical scientific publications

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    Motivation: The automatic analysis of scientific literature can support authors in writing their manuscripts

    A singular stochastic control problem with interconnected dynamics

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    In this paper we study a Markovian two-dimensional bounded-variation stochastic control problem whose state process consists of a difusive mean-reverting component and of a purely controlled one. The main problem's characteristic lies in the interaction of the two components of the state process: the mean-reversion level of the difusive component is an afne function of the current value of the purely controlled one. By relying on a combination of techniques from viscosity theory and free-boundary analysis, we provide the structure of the value function and we show that it satisfes a second-order smooth-ft principle. Such a regularity is then exploited in order to determine a system of functional equations solved by the two monotone continuous curves (free boundaries) that split the control problem's state space into three connected regions. Further properties of the free boundaries are also obtained

    MedEvi: Retrieving textual evidence of relations between biomedical concepts from Medline

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    Summary: Search engines running on MEDLINE abstracts have been widely used by biologists to find publications that are related to their research. The existing search engines such as PubMed, however, have limitations when applied for the task of seeking textual evidence of relations between given concepts. The limitations are mainly due to the problem that the search engines do not effectively deal with multi-term queries which may imply semantic relations between the terms. To address this problem, we present MedEvi, a novel search engine that imposes positional restriction on occurrences matching multi-term queries, based on the observation that terms with semantic relations which are explicitly stated in text are not found too far from each other. MedEvi further identifies additional keywords of biological and statistical significance from local context of matching occurrences in order to help users reformulate their queries for better results

    Left parietal tACS at alpha frequency induces a shift of visuospatial attention

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    Background Voluntary shifts of visuospatial attention are associated with a lateralization of parieto-occipital alpha power (7-13Hz), i.e. higher power in the hemisphere ipsilateral and lower power contralateral to the locus of attention. Recent noninvasive neuromodulation studies demonstrated that alpha power can be experimentally increased using transcranial alternating current stimulation (tACS). Objective/Hypothesis We hypothesized that tACS at alpha frequency over the left parietal cortex induces shifts of attention to the left hemifield. However, spatial attention shifts not only occur voluntarily (endogenous/ top-down), but also stimulus-driven (exogenous/ bottom-up). To study the task-specificity of the potential effects of tACS on attentional processes, we administered three conceptually different spatial attention tasks. Methods 36 healthy volunteers were recruited from an academic environment. In two separate sessions, we applied either high-density tACS at 10Hz, or sham tACS, for 35–40 minutes to their left parietal cortex. We systematically compared performance on endogenous attention, exogenous attention, and stimulus detection tasks. Results In the endogenous attention task, a greater leftward bias in reaction times was induced during left parietal 10Hz tACS as compared to sham. There were no stimulation effects in either the exogenous attention or the stimulus detection task. Conclusion The study demonstrates that high-density tACS at 10Hz can be used to modulate visuospatial attention performance. The tACS effect is task-specific, indicating that not all forms of attention are equally susceptible to the stimulation

    Hydration and the true water content of swellable clay minerals

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    Water affects biological, chemical and transportation processes as well as mechanical properties of soils. Thereby, clay mineral content determines the moisture balance of soils. In-situ moisture measurements depend on reliable calibration based on the true water content. Drying the soil at 105 °C is the most common procedure to determine the water content although it is known, swellable clay minerals retain hydration water up to much higher temperatures. The amplified water uptake and retention by swellable clay minerals results from hydration of interlayer cations. Thereby, the water binding mechanisms are complex due to structural heterogeneity and are determined by layer charge density and location of substitutions. While several experimental studies deal with the maximum water uptake of selected smectites and heating conditions for full dehydration a comprehensive understanding of the relation between the structure of smectites and water uptake/release is still missing. The Na-saturated smectite / water interface for the montmorillonite-beidellite series is investigated in the present work within the density functional theory (DFT). Layer charge is varied between 0.125 and 0.5 per formula unit [O10(OH)2] by substitution of Al3+ by Mg2+ in the octahedral sheet (montmorillonites) and by substitution of Si4+ by Al3+ in the tetrahedral sheets (beidellites). Starting from the water free supercells (with integer molar ratios), the number of water molecules is increased discretely. Stable hydration states (1H to 3H) do not necessarily correspond to the formation of water layers (1W to 3W) in the interlayer, which is deduced from the development of the basal spaces during hydration. With the help of ab initio thermodynamics, the energy states are related to temperature, and partial pressure of H2O and the resulting phase diagrams revealed hydration state in dependence of relative humidity (RH) as well as necessary temperatures for full dehydration to determine the true water content. Thereby it was shown that 2:1 layer silicates with a layer charge of 0.125 are swellable but reach only the 1H state even at 100% RH, but the removal of water molecules from the interlayer requires temperatures >110 °C and partial pressures of water <100 Pa. In contrast water uptake of smectites with layer charge 0.375 requires RH of >11% at room temperature, but dehydration occurs at moderate heating

    Higher-order sensitivity analysis of periodic 3-D eigenvalue problems for electromagnetic field calculations

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    An algorithm to perform a higher-order sensitivity analysis for electromagnetic eigenvalue problems is presented. By computing the eigenvalue and eigenvector derivatives, the Brillouin Diagram for periodic structures can be calculated. The discrete model is described using the Finite Integration Technique (FIT) with periodic boundaries, and the sensitivity analysis is performed with respect to the phase shift φ between the periodic boundaries. For validation, a reference solution is calculated by solving multiple eigenvalue problems (EVP). Furthermore, the eigenvalue derivatives are compared to reference values using finite difference (FD) formulas

    Apollo 14: Some geochemical aspects

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    Chemical analyses were obtained for five samples of Apollo 14 regolith fines, three 14230 core samples, soil clod 14049, breccias 14305 and 14319, 14310 basalt, and some separated phases. The chemical uniformity of these Apollo 14 samples indicates thorough mixing and/or uniform source rocks. Basalt 14310 can be matched well in composition by a four to one mixture of soil and plagioclase. The Eu(2+)/Eu(3+) ratios calculated for 14310 pigeonite and plagioclase are similar to those for Apollo 12 and 15 mare-type basalt phases; this indicates similar redox conditions. Apollo 14 samples are chemically similar to Apollo 12 and 15 KREEP as distinct from Apollo 11, 12, and 15 and Luna 16 mare-type basalts
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