5,552 research outputs found

    Design guidelines for use of adhesives and organic coatings in hybrid microcircuits

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    A study was conducted to investigate the reliability of organic adhesives in hybrid microcircuits. The objectives were twofold: (1) to identify and investigate problem areas that could result from the use of organic adhesives and (2) to develop evaluation tests to quantify the extent to which these problems occur for commercially available adhesives. Efforts were focused on electrically conductive adhesives. Also, a study was made to evaluate selected organic coatings for contamination protection for hybrid microcircuits

    Fractal dimension of domain walls in the Edwards-Anderson spin glass model

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    We study directly the length of the domain walls (DW) obtained by comparing the ground states of the Edwards-Anderson spin glass model subject to periodic and antiperiodic boundary conditions. For the bimodal and Gaussian bond distributions, we have isolated the DW and have calculated directly its fractal dimension dfd_f. Our results show that, even though in three dimensions dfd_f is the same for both distributions of bonds, this is clearly not the case for two-dimensional (2D) systems. In addition, contrary to what happens in the case of the 2D Edwards-Anderson spin glass with Gaussian distribution of bonds, we find no evidence that the DW for the bimodal distribution of bonds can be described as a Schramm-Loewner evolution processes.Comment: 6 pages, 5 figures. Accepted for publication in PR

    PHP1 ECONOMIC ANALYSIS OF THE BAVARIAN BLOOD AND PLASMA MARKET: LESSONS FOR THE FUTURE

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    The acute effects of daily nicotine intake on heart rate--a toxicokinetic and toxicodynamic modelling study.

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    Abstract Joint physiologically-based toxicokinetic and toxicodynamic (PBTK/TD) modelling was applied to simulate concentration–time profiles of nicotine, a well-known stimulant, in the human body following single and repeated dosing. Both kinetic and dynamic models were first calibrated by using in vivo literature data for the Caucasian population. The models were then used to estimate the blood and liver concentrations of nicotine in terms of the Area Under Curve (AUC) and the peak concentration (Cmax) for selected exposure scenarios based on inhalation (cigarette smoking), oral intake (nicotine lozenges) and dermal absorption (nicotine patches). The model simulations indicated that whereas frequent cigarette smoking gives rise to high AUC and Cmax in blood, the use of nicotine-rich dermal patches leads to high AUC and Cmax in the liver. Venous blood concentrations were used to estimate one of the most common acute effects, mean heart rate, both at rest and during exercise. These estimations showed that cigarette smoking causes a high peak heart rate, whereas dermal absorption causes a high mean heart rate over 48 h. This study illustrates the potential of using PBTK/TD modelling in the safety assessment of nicotine-containing products

    Stochastic Process Associated with Traveling Wave Solutions of the Sine-Gordon Equation

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    Stochastic processes associated with traveling wave solutions of the sine-Gordon equation are presented. The structure of the forward Kolmogorov equation as a conservation law is essential in the construction and so is the traveling wave structure. The derived stochastic processes are analyzed numerically. An interpretation of the behaviors of the stochastic processes is given in terms of the equation of motion.Comment: 12 pages, 9 figures; corrected typo

    LERW as an example of off-critical SLEs

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    Two dimensional loop erased random walk (LERW) is a random curve, whose continuum limit is known to be a Schramm-Loewner evolution (SLE) with parameter kappa=2. In this article we study ``off-critical loop erased random walks'', loop erasures of random walks penalized by their number of steps. On one hand we are able to identify counterparts for some LERW observables in terms of symplectic fermions (c=-2), thus making further steps towards a field theoretic description of LERWs. On the other hand, we show that it is possible to understand the Loewner driving function of the continuum limit of off-critical LERWs, thus providing an example of application of SLE-like techniques to models near their critical point. Such a description is bound to be quite complicated because outside the critical point one has a finite correlation length and therefore no conformal invariance. However, the example here shows the question need not be intractable. We will present the results with emphasis on general features that can be expected to be true in other off-critical models.Comment: 45 pages, 2 figure
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