175 research outputs found

    Daniel Schorr First Amendment Award Remarks, 1986

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    Transcript of remarks made by Daniel Schorr, American journalist, upon receiving the Ford Hall Forum First Amendment Award on May 11, 1986.https://dc.suffolk.edu/fhf-docs/1028/thumbnail.jp

    Daniel Schorr receives the Ford Hall Forum\u27s First Amendment Award, audio recording and transcript

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    https://dc.suffolk.edu/fhf-av/1019/thumbnail.jp

    A thorough investigation of the crystal structure of willemite-type Zn2GeO4

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    The thermodynamically stable phase of Zn2GeO4 contains tetrahedrally coordinated cations only and crystallizes isostructurally to Zn2SiO4 (willemite, space group R3? , no. 148). While this material is considered for a plethora of energy-related applications, such as transparent conducting oxide, battery material and photocatalyst, cation ordering in the crystal structure has not been investigated thoroughly. We have therefore re-determined the crystal structure of Zn2GeO4 using a combination of X-ray and neutron powder diffraction. The additional neutron diffraction study helps to distinguish between the isoelectronic Zn2+ and Ge4+ cations and yields valuable information about a partial or complete cation permutation in this material. The experimental study is supported by first-principles calculations on the structural properties of Zn2GeO4 utilizing a standard generalized gradient approximation, and the more accurate hybrid functional HSE06. In order to better understand cation permutations, additional calculations including defective Zn2GeO4 have been performed based on a supercell approach. Our results show that, with the preparation conditions applied, cation permutation is unlikely to occur in our samples

    Preclinical efficacy in investigator's brochures:Stakeholders' views on measures to improve completeness and robustness

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    Aims:Research ethics committees and regulatory agencies assess whether the benefits of a proposed early-stage clinical trial outweigh the risks based on preclinical studies reported in investigator's brochures (IBs). Recent studies have indicated that the reporting of preclinical evidence presented in IBs does not enable proper risk-benefit assessment. We interviewed different stakeholders (regulators, research ethics committee members, preclinical and clinical researchers, ethicists, and metaresearchers) about their views on measures to increase the completeness and robustness of preclinical evidence reporting in IBs. Methods: This study was preregistered (https://osf.io/nvzwy/). We used purposive sampling and invited stakeholders to participate in an online semistructured interview between March and June 2021. Themes were derived using inductive content analysis. We used a strengths, weaknesses, opportunities and threats matrix to categorize our findings. Results: Twenty-seven international stakeholders participated. The interviewees pointed to several strengths and opportunities to improve completeness and robustness, mainly more transparent and systematic justifications for the included studies. However, weaknesses and threats were mentioned that could undermine efforts to enable a more thorough assessment: The interviewees stressed that current review practices are sufficient to ensure the safe conduct of first-in-human trials. They feared that changes to the IB structure or review process could overburden stakeholders and slow drug development. Conclusion: In principle, more robust decision-making processes align with the interests of all stakeholders and with many current initiatives to increase the translatability of preclinical research and limit uninformative or ill-justified trials early in the development process. Further research should investigate measures that could be implemented to benefit all stakeholders.</p

    Reactivación de la industria argentina, concentración, extranjerización y crecientes desequilibrios comerciales con Brasil

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    El artículo identifica algunos de los principales rasgos que caracterizan la reactivación de la economía y, en especial, de la industria argentina en la posconvertibilidad, a partir del quiebre del régimen de conversión fija con el dólar estadounidense. Se aborda el estudio de los sesgos estructurales que revela esa importante recuperación fabril en su relación con los que caracterizaron su desempeño durante los años noventa (patrón productivo, concentración económica y extranjerización) y las modalidades de inserción a escala mundial. Al respecto, se presta particular atención a sus impactos en términos del intercambio comercial manufacturero, en especial con el Brasil.This paper identifies some of the main features that characterize the economic recovery, specially the “postconvertibility” Argentinean industry, from the break down of the fixed conversion regime with the American dollar. This article approaches the structural biases that reveals this significant industrial recovery in its relation with those who characterized its performance during the nineties (pattern of production, economic concentration and denationalization) and the particularities of insertion on a worldwide scale. In connection with this, particular attention is paid to its impacts in terms of manufacturing trade, particularly with Brazil.Fil: Azpiazu, Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Facultad Latinoamericana de Ciencias Sociales; ArgentinaFil: Schorr, Martín. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Facultad Latinoamericana de Ciencias Sociales; Argentin

    REACTIVACION DE LA INDUSTRIA ARGENTINA, CONCENTRACIÓN, EXTRANJERIZACIÓN Y CRECIENTES DESEQUILIBRIOS COMERCIALES CON BRASIL

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    El artículo identifica algunos de los principales rasgos que caracterizan la reactivaciónde la economía y, en especial, de la industria argentina en la posconvertibilidad, a partir delquiebre del régimen de conversión fija con el dólar estadounidense. Se aborda el estudio de lossesgos estructurales que revela esa importante recuperación fabril en su relación con los quecaracterizaron su desempeño durante los años noventa (patrón productivo, concentracióneconómica y extranjerización) y las modalidades de inserción a escala mundial. Al respecto, sepresta particular atención a sus impactos en términos del intercambio comercial manufacturero,en especial con el Brasil
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