735 research outputs found
An analysis of aircraft accidents involving fires
All U. S. Air Carrier accidents between 1963 and 1974 were studied to assess the extent of total personnel and aircraft damage which occurred in accidents and in accidents involving fire. Published accident reports and NTSB investigators' factual backup files were the primary sources of data. Although it was frequently not possible to assess the relative extent of fire-caused damage versus impact damage using the available data, the study established upper and lower bounds for deaths and damage due specifically to fire. In 12 years there were 122 accidents which involved airframe fires. Eighty-seven percent of the fires occurred after impact, and fuel leakage from ruptured tanks or severed lines was the most frequently cited cause. A cost analysis was performed for 300 serious accidents, including 92 serious accidents which involved fire. Personal injury costs were outside the scope of the cost analysis, but data on personnel injury judgements as well as settlements received from the CAB are included for reference
Modeling, simulation, and control of an extraterrestrial oxygen production plant
The immediate objective is the development of a new methodology for simulation of process plants used to produce oxygen and/or other useful materials from local planetary resources. Computer communication, artificial intelligence, smart sensors, and distributed control algorithms are being developed and implemented so that the simulation or an actual plant can be controlled from a remote location. The ultimate result of this research will provide the capability for teleoperation of such process plants which may be located on Mars, Luna, an asteroid, or other objects in space. A very useful near-term result will be the creation of an interactive design tool, which can be used to create and optimize the process/plant design and the control strategy. This will also provide a vivid, graphic demonstration mechanism to convey the results of other researchers to the sponsor
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Predictors of Acute Liver Failure in Patients With Acute Hepatitis A: An Analysis of the 2016-2018 San Diego County Hepatitis A Outbreak.
Background:Between 2016 and 2018, San Diego County experienced a hepatitis A outbreak with a historically high mortality rate (3.4%) that highlighted the need for early recognition of those at risk of developing acute liver failure (ALF). Methods:A retrospective case series of adult hospitalized patients with acute hepatitis A. Results:One hundred six patients with hepatitis A were studied, of whom 11 (10.4%) developed ALF, of whom 7 (6.6%) died. A history of alcohol abuse, hyperbilirubinemia, hypoalbuminemia, hyponatremia, and anemia were associated with increased odds of developing ALF. Initial Maddrey's and Model of End-Stage Liver Disease Sodium (MELD-Na) scores were also associated with the development of ALF. Multivariable analysis showed that a higher initial MELD-Na score (odds ratio [OR], 1.205; 95% confidence interval [CI], 1.018-1.427) and a lower initial serum albumin concentration (OR, 9.35; 95% CI, 1.15-76.9) were associated with increased odds of developing ALF. Combining serum albumin and MELD-Na (SAM; C-statistic, 0.8878; 95% CI, 0.756-0.988) yielded a model that was not better than either serum albumin (C-statistic, 0.852; 95% CI, 0.675-0.976) or MELD-Na (C-statistic, 0.891; 95% CI, 0.784-0.968; P = .841). Finally, positive blood cultures were more common among patients with ALF compared with those without ALF (63.6% vs 4.3%; P < .00001). Conclusions:Hypoalbuminemia was associated with an increased risk of ALF in patients with acute hepatitis A. Positive blood cultures and septic shock as a cause of death were common among patients with ALF. Providers caring for patients with acute hepatitis A should monitor for early signs of sepsis and consider empiric antibiotics, especially in patients presenting with hypoalbuminemia
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Public Use of an Online Advanced Traveler Guidance Information System: Trust in the e-Service and the Agency
Public transit system web sites have become a tool of choice for many citizens to obtain transit route information and to assist with trip planning. For many of these citizens, the web interface has become the only method of communication with the public service agency and the primary method of obtaining information about transit services. This model-based, multi-method study analyzes data from more than 450 survey respondents and twenty-four focus group participants, seeks to understand the end user citizen trust experience in their interaction with e-government transit web sites. Results of this e-service study provide useful insights into how citizen perceptions of the transit service and transit agencies are affected through web site e-service use
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The Evolution of Mentorship Capacity Development in Low- and Middle-Income Countries: Case Studies from Peru, Kenya, India, and Mozambique.
Following the Fogarty International Center-supported "Mentoring the Mentors" workshops in South America, Africa, and Asia, approaches and guidelines for mentorship at institutions within these low- and middle-income country (LMIC) contexts, appropriate for the respective regional resources and culture, were implemented. Through the presentation of case studies from these three geographic regions, this article illustrates the institutional mentorship infrastructure before the workshop and the identified gaps used to implement strategies to build mentorship capacity at the Universidad Peruana Cayetano Heredia (Peru), Kenya Medical Research Institute (Kenya), Saint John's Research Institute (India), and Eduardo Mondlane University (Mozambique). These case studies illustrate three findings: first, that mentorship programs in LMICs have made uneven progress, and institutions with existing programs have exhibited greater advancement to their mentoring capacity than institutions without formal programs before the workshops. Second, mentoring needs assessments help garner the support of institutional leadership and create local ownership. Third, developing a culture of mentorship that includes group mentoring activities at LMIC institutions can help overcome the shortage of trained mentors. Regardless of the stage of mentoring programs, LMIC institutions can work toward developing sustainable, culturally effective mentorship models that further the partnership of early career scientists and global health
Stanley Hauerwas\u27 Approach to Christian Marital and Sex Ethics: A Review and Speculative Expansion
Few places in congregational and denominational life are more fraught with tension and division than conversations about marital and sex ethics. Systemic abuses mingled together with individual failures on this issue has led to confusion, conflict, and chaos. Worse yet, the remedies proposed—and they are many—tend to either double down on “Traditional” values or seek massive reformation of Christian convictions in light of Modern philosophical, anthropological, and sociological presuppositions. Interlocutors quickly come to an impasse and fragmentation occurs. The catalyst for these conflicts is often debates over same-sex marriage, but one does not have to wade far into this conversation to discover that the issues run deeper than this single topic.
This dissertation emerges from a conviction that this doesn’t have to be the story of the Protestant church in America in late-20th and early-21st century culture. The opportunity to reclaim Christian unity while maintaining a unique understanding of marriage and sex, which creates inclusive space for same-sex oriented Christians, is possible. To get there, though, the shackles of so many faulty assumptions about this topic will have to fall off and those previously bound will have to embrace the liberty offered them in a shared Christian narrative, community, and character. It is precisely these themes that theological ethicist, Stanley Hauerwas, has spent a career elucidating and it is through a Hauerwasian approach that this dissertation hopes to correct the church’s current broken proclamation and damaged practices of marriage and sex
Information Systems and Healthcare XXXVII: When Your Employer Provides Your Personal Health Record—Exploring Employee Perceptions of an Employer-Sponsored PHR System
A growing number of employers provide electronic personal health records (PHRs) as a service to employees as part of a health benefit program. However, a variety of unique issues related to attitudes and adoption arise when a PHR is hosted by the employer, and little research has addressed this relationship. This article reports the findings from an exploratory study of factors that influence employee perceptions, concerns, and expectations related to an employer—sponsored PHR service, with data from 132 employees of a large U.S. corporation. Attitudes toward PHR systems and employee perceptions and concerns identified in prior research are evaluated. Despite studies suggesting significant demand for PHR products across the general public, especially those that are offered at no cost to the user, responses indicated unique barriers to use, as well as opportunities, for employer-sponsored PHRs. The future role of employers as sponsors of PHRs is discussed in light of obstacles and strategies to improve system use, and the need to help employees realize the potential value of employer-sponsored PHRs
Summer Precipitation Predicts Spatial Distributions of Semiaquatic Mammals
Citation: Ahlers, A. A., Cotner, L. A., Wolff, P. J., Mitchell, M. A., Heske, E. J., & Schooley, R. L. (2015). Summer Precipitation Predicts Spatial Distributions of Semiaquatic Mammals. Plos One, 10(8), 14. doi:10.1371/journal.pone.0135036Climate change is predicted to increase the frequency of droughts and intensity of seasonal precipitation in many regions. Semiaquatic mammals should be vulnerable to this increased variability in precipitation, especially in human-modified landscapes where dispersal to suitable habitat or temporary refugia may be limited. Using six years of presence-absence data (2007-2012) spanning years of record-breaking drought and flood conditions, we evaluated regional occupancy dynamics of American mink (Neovison vison) and muskrats (Ondatra zibethicus) in a highly altered agroecosystem in Illinois, USA. We used noninvasive sign surveys and a multiseason occupancy modeling approach to estimate annual occupancy rates for both species and related these rates to summer precipitation. We also tracked radiomarked individuals to assess mortality risk for both species when moving in terrestrial areas. Annual model-averaged estimates of occupancy for mink and muskrat were correlated positively to summer precipitation. Mink and muskrats were widespread during a year (2008) with above-average precipitation. However, estimates of site occupancy declined substantially for mink (0.56) and especially muskrats (0.09) during the severe drought of 2012. Mink are generalist predators that probably use terrestrial habitat during droughts. However, mink had substantially greater risk of mortality away from streams. In comparison, muskrats are more restricted to aquatic habitats and likely suffered high mortality during the drought. Our patterns are striking, but a more mechanistic understanding is needed of how semiaquatic species in human-modified ecosystems will respond ecologically in situ to extreme weather events predicted by climate-change models
Diabetes mellitus and hyperglycemia control on the risk of colorectal adenomatous polyps: a retrospective cohort study
BACKGROUND: Colorectal cancer (CRC) develops from colorectal adenomatous polyps. This study is to determine if diabetes mellitus (DM), its treatment, and hemoglobin A1c (HbA1c) level are associated with increased risk of colorectal adenomatous polyps.
METHODS: This was a retrospective cohort study that included patients who had at least one colonoscopy and were continuously enrolled in a single managed care organization during a 10-year period (2002-2012). Of these patients (N = 11,933), 1800 were randomly selected for chart review to examine the details of colonoscopy and pathology findings and to confirm the diagnosis of DM. Multivariable logistic regression analyses were performed to assess the associations between DM, its treatment, HbA1c level and adenomatous polyps (our main outcome).
RESULTS: Among the total of 11,933 patients with a mean (standard deviation) age of 56 (± 8.8) years, 2306 (19.3%) had DM and 75 (0.6%) had CRC. Among the 1800 under chart review, 445 (24.7%) had DM, 11 (0.6%) had CRC and 537 (29.8%) had adenomatous polyps. In bivariate analysis, patients with DM had 1.45 odds of developing adenomatous polyps compared to those without DM. This effect was attenuated (odds ratio = 1.25, 95% CI: 0.96-1.62, p = 0.09) after adjusting for confounders such as age, gender, race/ethnicity, and body mass index. There was no significant association between type or duration of DM treatment or HbA1c level and adenomatous polyps.
CONCLUSIONS: Our study confirmed the known increased risk of adenomatous polyps with advancing age, male gender, Hispanic race/ethnicity and higher body mass index. Although it suggested an association between DM and adenomatous polyps, a statistically significant association was not observed after controlling for other potential confounders. Further studies with a larger sample size are needed to further elucidate this relationship
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