789 research outputs found
Parks v. Mr. Ford and the Development of a Rational Approach to Resolving Inconsistencies in Results of Due Process Attacks on Creditors\u27 Remedies
The American yeoman: an historical ecology of production in colonial Pennsylvania
This study examines climate, landscape and agricultural products, but it is essentially a study of an American yeoman class in colonial Pennsylvania. Yeomen emerged out of feudal hierarchies of manorial Europe as owner-operator agriculturalists. As part of the British colonization of North America, they reformed themselves into a social majority. In Pennsylvania they embraced shifting agriculture and a suite of risk-minimizing practices in response to changing weather patterns. By the end of the 18th century, the yeoman class had become a victim of its own success and it gave way to a class of farmers who used hired labor on rented land to chase a strong grain market. This work examines their changing ecological relations in order to explicate the American yeomen’s transformation into farmers. Historical ecology is an emerging theoretical approach which seeks to combine climate, social history, geography, and the practices of production in order to understand changes in landscape over the long-term. Information concerning class descriptions, agricultural products, livestock, bound labor, and risk-management strategies from 3551 inventoried households which contained about 25,000 people are placed within the context of social history, climatological observations and reconstructions, and geographic information system (GIS) data in order to chronicle the last days of the American yeoman
Accessory Piriformis Muscle
Emily Scholl, Michael Kellner, David R. Terfera, and Kevin R. Kelliher's poster discussing the piriformis muscle.Faculty Research Day 2018: Doctoral Student Poster 2nd Plac
Secular resonance sweeping of the main asteroid belt during planet migration
We calculate the eccentricity excitation of asteroids produced by the
sweeping secular resonance during the epoch of planetesimal-driven
giant planet migration in the early history of the solar system. We derive
analytical expressions for the magnitude of the eccentricity change and its
dependence on the sweep rate and on planetary parameters; the sweeping
leads to either an increase or a decrease of eccentricity depending on an
asteroid's initial orbit. Based on the slowest rate of sweeping that
allows a remnant asteroid belt to survive, we derive a lower limit on Saturn's
migration speed of \sim0.15\AU\My^{-1} during the era that the
resonance swept through the inner asteroid belt (semimajor axis range
2.1--2.8\AU). This rate limit is for Saturn's current eccentricity, and
scales with the square of Saturn's eccentricity; the limit on Saturn's
migration rate could be lower if Saturn's eccentricity were lower during its
migration. Applied to an ensemble of fictitious asteroids, our calculations
show that a prior single-peaked distribution of asteroid eccentricities would
be transformed into a double-peaked distribution due to the sweeping of the
. Examination of the orbital data of main belt asteroids reveals that
the proper eccentricities of the known bright () asteroids may be
consistent with a double-peaked distribution. If so, our theoretical analysis
then yields two possible solutions for the migration rate of Saturn and for the
dynamical states of the pre-migration asteroid belt: a dynamically cold state
(single-peaked eccentricity distribution with mean of ) linked with
Saturn's migration speed \sim 4\AU\My^{-1}, or a dynamically hot state
(single-peaked eccentricity distribution with mean of ) linked with
Saturn's migration speed \sim 0.8\AU\My^{-1}.Comment: 32 pages, 7 figures. Accepted for publication in ApJ on Mar. 1, 201
Anatomy of the western Java plate interface from depth-migrated seismic images
Newly pre-stack depth-migrated seismic images resolve the structural details of the western Java forearc and plate interface. The structural segmentation of the forearc into discrete mechanical domains correlates with distinct deformation styles. Approximately 2/3 of the trench sediment fill is detached and incorporated into frontal prism imbricates, while the floor sequence is underthrust beneath the décollement. Western Java, however, differs markedly from margins such as Nankai or Barbados, where a uniform, continuous décollement reflector has been imaged. In our study area, the plate interface reveals a spatially irregular, nonlinear pattern characterized by the morphological relief of subducted seamounts and thicker than average patches of underthrust sediment. The underthrust sediment is associated with a low velocity zone as determined from wide-angle data. Active underplating is not resolved, but likely contributes to the uplift of the large bivergent wedge that constitutes the forearc high. Our profile is located 100 km west of the 2006 Java tsunami earthquake. The heterogeneous décollement zone regulates the friction behavior of the shallow subduction environment where the earthquake occurred. The alternating pattern of enhanced frictional contact zones associated with oceanic basement relief and weak material patches of underthrust sediment influences seismic coupling and possibly contributed to the heterogeneous slip distribution. Our seismic images resolve a steeply dipping splay fault, which originates at the décollement and terminates at the sea floor and which potentially contributes to tsunami generation during co-seismic activity
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Detailed Visual Cortical Responses Generated by Retinal Sheet Transplants in Rats with Severe Retinal Degeneration.
To combat retinal degeneration, healthy fetal retinal sheets have been successfully transplanted into both rodent models and humans, with synaptic connectivity between transplant and degenerated host retina having been confirmed. In rodent studies, transplants have been shown to restore responses to flashes of light in a region of the superior colliculus corresponding to the location of the transplant in the host retina. To determine the quality and detail of visual information provided by the transplant, visual responsivity was studied here at the level of visual cortex where higher visual perception is processed. For our model, we used the transgenic Rho-S334ter line-3 rat (both sexes), which loses photoreceptors at an early age and is effectively blind at postnatal day 30. These rats received fetal retinal sheet transplants in one eye between 24 and 40 d of age. Three to 10 months following surgery, visually responsive neurons were found in regions of primary visual cortex matching the transplanted region of the retina that were as highly selective as normal rat to stimulus orientation, size, contrast, and spatial and temporal frequencies. Conversely, we found that selective response properties were largely absent in nontransplanted line-3 rats. Our data show that fetal retinal sheet transplants can result in remarkably normal visual function in visual cortex of rats with a degenerated host retina and represents a critical step toward developing an effective remedy for the visually impaired human population.SIGNIFICANCE STATEMENT Age-related macular degeneration and retinitis pigmentosa lead to profound vision loss in millions of people worldwide. Many patients lose both retinal pigment epithelium and photoreceptors. Hence, there is a great demand for the development of efficient techniques that allow for long-term vision restoration. In this study, we transplanted dissected fetal retinal sheets, which can differentiate into photoreceptors and integrate with the host retina of rats with severe retinal degeneration. Remarkably, we show that transplants generated visual responses in cortex similar in quality to normal rats. Furthermore, transplants preserved connectivity within visual cortex and the retinal relay from the lateral geniculate nucleus to visual cortex, supporting their potential application in curing vision loss associated with retinal degeneration
Influence of anterior mitral valve length and septal wall thickness on the prevalence of left ventricular outflow tract obstruction in hypertrophic cardiomyopathy
Computational and phylogenetic validation of nematode horizontal gene transfer
Sequencing of expressed genes has shown that nematodes, particularly the plant-parasitic nematodes, have genes purportedly acquired from other kingdoms by horizontal gene transfer. The prevailing orthodoxy is that such transfer has been a driving force in the evolution of niche specificity, and a recent paper in BMC Evolutionary Biology that presents a detailed phylogenetic analysis of cellulase genes in the free-living nematode Pristionchus pacificus at the species, genus and family levels substantiates this hypothesis
Horizontally transferred genes in plant-parasitic nematodes: a high-throughput genomic approach
BACKGROUND: Published accounts of horizontally acquired genes in plant-parasitic nematodes have not been the result of a specific search for gene transfer per se, but rather have emerged from characterization of individual genes. We present a method for a high-throughput genome screen for horizontally acquired genes, illustrated using expressed sequence tag (EST) data from three species of root-knot nematode, Meloidogyne species. RESULTS: Our approach identified the previously postulated horizontally transferred genes and revealed six new candidates. Screening was partially dependent on sequence quality, with more candidates identified from clustered sequences than from raw EST data. Computational and experimental methods verified the horizontal gene transfer candidates as bona fide nematode genes. Phylogenetic analysis implicated rhizobial ancestors as donors of horizontally acquired genes in Meloidogyne. CONCLUSIONS: High-throughput genomic screening is an effective way to identify horizontal gene transfer candidates. Transferred genes that have undergone amelioration of nucleotide composition and codon bias have been identified using this approach. Analysis of these horizontally transferred gene candidates suggests a link between horizontally transferred genes in Meloidogyne and parasitism
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