245 research outputs found

    Zur Europäisierung des Verwaltungsrechts

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     Die Europäisierung des Verwaltungsrechts ist ein fortschreitender, nicht endender Prozess. Betroffen sind Kernmaterien der innerstaatlichen Rechtsordnung wie etwa das Allgemeine Verwaltungsrecht, das Verwaltungsverfahrensrecht und das Verwaltungsprozessrecht. Der Beitrag analysiert die Einwirkungen des supranationalen Unionsrechts auf jene Rechtsgebiete und weist nach, dass das systematisch angelegte deutsche Verwaltungsrecht und die gut strukturierte Rechtsdogmatik in der Lage sind, die Europäisierung der innerstaatlichen Rechtsordnung zu bewältigen. Dabei zeigt sich, dass das Europarecht nicht nur Herausforderungen für das nationale Recht und das überkommene Rechtsdenken bereithält, sondern auch Impulse für die Modernisierung des deutschen Verwaltungsrechts setzt.&#160

    Measurement of polarisation observables in Ks0Σ+K^0_s\Sigma^+ photoproduction off the proton

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    The reaction γpKS0Σ+\gamma \, p \rightarrow K^0_S\,\Sigma^+ is studied in the photon energy range from threshold. Linearly polarised photon beams from coherent bremsstrahlung enabled the first measurement of photon beam asymmetries in this reaction up to Eγ=2250E_\gamma = 2250 MeV. In addition, the recoil hyperon polarisation was determined through the asymmetry in the weak decay Σ+pπ0\Sigma^+ \rightarrow p \pi^0 up to Eγ=1650E_\gamma = 1650 MeV. The data are compared to partial wave analyses, and the possible impact on the interpretation of a recently observed cusp-like structure near the KK^* thresholds is discussed.Comment: 6 pages, 5 figures. References [8,9,10,11] which were not on the original submission are now include

    Measurement of the Beam Asymmetry Σ\Sigma in the Forward Direction for pi0 Photoproduction

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    Photoproduction of neutral pions has been studied with the CBELSA/TAPS detector for photon energies between 0.92 and 1.68~GeV at the electron accelerator ELSA. The beam asymmetry~Σ\Sigma has been extracted for 115<θc.m.<155115^\circ < \theta_{\rm c.m.} < 155^\circ of the π0\pi^0~meson and for θc.m.<60\theta_{\rm c.m.} < 60^\circ. The new beam asymmetry data improve the world database for photon energies above 1.5~GeV and, by covering the very forward region, extend previously published data for the same reaction by our collaboration. The angular dependence of Σ\Sigma shows overall good agreement with the SAID parameterization.Comment: 11 pages, 10 figures, published in Phys. Rev. C, included LEPS data and MAID 2007 predictions for comparison with our dat

    Photoproduction of Neutral Pions off Protons

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    Photoproduction of neutral pions has been studied with the CBELSA/TAPS detector in the reaction γppπ0\gamma p\to p\pi^0 for photon energies between 0.85 and 2.50 GeV. The π0\pi^0 mesons are observed in their dominant neutral decay mode: π0γγ\pi^0\to\gamma\gamma. For the first time, the differential cross sections cover the very forward region, θc.m.<60\theta_{\rm c.m.}<60^\circ. A partial-wave analysis of these data within the Bonn-Gatchina framework observes the high-mass resonances G17G_{17}(2190), D13D_{13}(2080), and D15D_{15}(2070).Comment: 12 pages, 9 figures, minor modifications to PWA sectio

    Photoproduction of meson pairs: First measurement of the polarization observable I^s

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    The polarization observable I^s, a feature exclusive to the acoplanar kinematics of multi-meson final states produced via linearly polarized photons, has been measured for the first time. Results for the reaction g p -> p pi0 eta are presented for incoming photon energies between 970 MeV and 1650 MeV along with the beam asymmetry I^c. The comparably large asymmetries demonstrate a high sensitivity of I^s to the dynamics of the reaction. Fits using Bonn-Gatchina partial wave analysis demonstrate that the new polarization observables carry significant information on the contributing partial waves.Comment: 11 pages, 6 figures, v2 to appear in Phys. Lett.

    In-medium ω\omega mass from the γ+Nbπ0γ+X\gamma + Nb \to \pi^{0}\gamma + X reaction

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    Data on the photoproduction of ω\omega mesons on nuclei have been re-analyzed in a search for in-medium modifications. The data were taken with the Crystal Barrel(CB)/TAPS detector system at the ELSA accelerator facility in Bonn. First results from the analysis of the data set were published by D. Trnka et al. in Phys. Rev. Lett 94 (2005) 192303 \cite{david}, claiming a lowering of the ω\omega mass in the nuclear medium by 14% at normal nuclear matter density. The extracted ω\omega line shape was found to be sensitive to the background subtraction. For this reason a re-analysis of the same data set has been initiated and a new method has been developed to reduce the background and to determine the shape and absolute magnitude of the background directly from the data. Details of the re-analysis and of the background determination are described. The ω\omega signal on the NbNb target, extracted in the re-analysis, does not show a deviation from the corresponding line shape on a LH2LH_2 target, measured as reference. The earlier claim of an in-medium mass shift is thus not confirmed. The sensitivity of the ω\omega line shape to different in-medium modification scenarios is discussed.Comment: 13 pages and 11 figures, submitted for publicatio

    Quasi-free photoproduction of eta-mesons of the neutron

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    Quasi-free photoproduction of eta-mesons off nucleons bound in the deuteron has been measured with the CBELSA/TAPS detector for incident photon energies up to 2.5 GeV at the Bonn ELSA accelerator. The eta-mesons have been detected in coincidence with recoil protons and recoil neutrons, which allows a detailed comparison of the quasi-free n(gamma,eta)n and p(gamma,eta)p reactions. The excitation function for eta-production off the neutron shows a pronounced bump-like structure at W=1.68 GeV (E_g ~ 1 GeV), which is absent for the proton.Comment: accepted for publication in Phys. Rev. Let

    K^0 pi^0 Sigma^+ and K^*0 Sigma^+ photoproduction off the proton

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    The exclusive reactions γpK0Σ+(1189)\gamma p \to K^{*0} \Sigma^+(1189) and γpK0π0Σ+(1189)\gamma p \to K^{0} \pi^{0}\Sigma^+(1189), leading to the p 4π0\pi^{0} final state, have been measured with a tagged photon beam for incident energies from threshold up to 2.5 GeV. The experiment has been performed at the tagged photon facility of the ELSA accelerator (Bonn). The Crystal Barrel and TAPS detectors were combined to a photon detector system of almost 4π\pi geometrical acceptance. Differential and total cross sections are reported. At energies close to the threshold, a flat angular distribution has been observed for the reaction γpK0π0Σ+\gamma p\to K^{0} \pi^{0}\Sigma^+ suggesting dominant s-channel production. Σ(1385)\Sigma^*(1385) and higher lying hyperon states have been observed. An enhancement in the forward direction in the angular distributions of the reaction γpK0Σ+\gamma p \to K^{*0}\Sigma^+ indicates a tt-channel exchange contribution to the reaction mechanism. The experimental data are in reasonable agreement with recent theoretical predictions.Comment: 11 pages, 13 figures, submitted to EPJ

    Determination of caspase-3 activation fails to predict chemosensitivity in primary acute myeloid leukemia blasts

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    BACKGROUND: Ex-vivo chemosensitivity tests that measure cell death induction may predict treatment outcome and, therefore, represent a powerful instrument for clinical decision making in cancer therapy. Such tests are, however, work intensive and, in the case of the DiSC-assay, require at least four days. Induction of apoptosis is the mode of action of anticancer drugs and should, therefore, result in the induction of caspase activation in cells targeted by anticancer therapy. METHODS: To determine, whether caspase activation can predict the chemosensitivity, we investigated enzyme activation of caspase-3, a key executioner caspase and correlated these data with chemosensitivity profiles of acute myeloid leukemia (AML) blasts. RESULTS: There was, however, no correlation between the ex-vivo chemosensitivity assessed by measuring the overall rates of cell death by use of the DiSC-assay and caspase-3 activation. CONCLUSION: Thus, despite a significant reduction of duration of the assay from four to one day, induction of apoptosis evaluated by capase-3 activity does not seem to be a valid surrogate marker for chemosensitivity

    Linearly polarised photon beams at ELSA and measurement of the beam asymmetry in pi^0-photoproduction off the proton

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    At the electron accelerator ELSA a linearly polarised tagged photon beam is produced by coherent bremsstrahlung off a diamond crystal. Orientation and energy range of the linear polarisation can be deliberately chosen by accurate positioning of the crystal with a goniometer. The degree of polarisation is determined by the form of the scattered electron spectrum. Good agreement between experiment and expectations on basis of the experimental conditions is obtained. Polarisation degrees of P = 40% are typically achieved at half of the primary electron energy. The determination of P is confirmed by measuring the beam asymmetry, \Sigma, in pi^0 photoproduction and a comparison of the results to independent measurements using laser backscattering.Comment: 9 pages, 10 figures, submitted to EPJ
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