1,212 research outputs found
Exploring within-person variability in qualitative negative and positive Emotional Granularity by means of Latent Markov Factor Analysis
Emotional granularity (EG) is an individual’s ability to describe their emotional experiences in a nuanced and specific way. In this paper, we propose that researchers adopt latent Markov factor analysis (LMFA) to investigate within-person variability in qualitative EG (i.e., variability in distinct granularity patterns between specific emotions across time). LMFA clusters measurement occasions into latent states according to state-specific measurement models. We argue that state-specific measurement models of repeatedly assessed emotion items can provide information about qualitative EG at a given point in time. Applying LMFA to the area of EG for negative and positive emotions separately by using data from an experience sampling study with 11,662 measurement occasions across 139 participants, we found three latent EG states for the negative emotions and three for the positive emotions. Momentary stress significantly predicted transitions between the EG states for both the negative and positive emotions. We further identified two and three latent classes of individuals who differed in state trajectories for negative and positive emotions, respectively. Neuroticism and dispositional mood regulation predicted latent class membership for negative (but not for positive) emotions. We conclude that LMFA may enrich EG research by enabling more fine-grained insights into variability in qualitative EG patterns
Pro-oxidant effect of ALA is implicated in mitochondrial dysfunction of HepG2 cells
Heme biosynthesis begins in the mitochondrion with the formation of delta-aminolevulinic acid (ALA). In acute intermittent porphyria, hereditary tyrosinemia type I and lead poisoning patients, ALA is accumulated in plasma and in organs, especially the liver. These diseases are also associated with neuromuscular dysfunction and increased incidence of hepatocellular carcinoma. Many studies suggest that this damage may originate from ALA-induced oxidative stress following its accumulation. Using the MnSOD as an oxidative stress marker, we showed here that ALA treatment of cultured cells induced ROS production, increasing with ALA concentration. The mitochondrial energetic function of ALA-treated HepG2 cells was further explored. Mitochondrial respiration and ATP content were reduced compared to control cells. For the 300 μM treatment, ALA induced a mitochondrial mass decrease and a mitochondrial network imbalance although neither necrosis nor apoptosis were observed. The up regulation of PGC-1, Tfam and ND5 genes was also found; these genes encode mitochondrial proteins involved in mitochondrial biogenesis activation and OXPHOS function. We propose that ALA may constitute an internal bioenergetic signal, which initiates a coordinated upregulation of respiratory genes, which ultimately drives mitochondrial metabolic adaptation within cells. The addition of an antioxidant, Manganese(III) tetrakis(1-methyl-4-pyridyl)porphyrin (MnTMPyP), resulted in improvement of maximal respiratory chain capacity with 300 μM ALA. Our results suggest that mitochondria, an ALA-production site, are more sensitive to pro-oxidant effect of ALA, and may be directly involved in pathophysiology of patients with inherited or acquired porphyria
Open charm and charmonium production at relativistic energies
We calculate open charm and charmonium production in reactions at
= 200 GeV within the hadron-string dynamics (HSD) transport approach
employing open charm cross sections from and reactions that are
fitted to results from PYTHIA and scaled in magnitude to the available
experimental data. Charmonium dissociation with nucleons and formed mesons to
open charm ( pairs) is included dynamically. The 'comover'
dissociation cross sections are described by a simple phase-space model
including a single free parameter, i.e. an interaction strength , that
is fitted to the suppression data for collisions at SPS
energies. As a novel feature we implement the backward channels for charmonium
reproduction by channels employing detailed balance. From our
dynamical calculations we find that the charmonium recreation is comparable to
the dissociation by 'comoving' mesons. This leads to the final result that the
total suppression at = 200 GeV as a function of centrality
is slightly less than the suppression seen at SPS energies by the NA50
Collaboration, where the 'comover' dissociation is substantial and the backward
channels play no role. Furthermore, even in case that all directly produced
mesons dissociate immediately (or are not formed as a mesonic state),
a sizeable amount of charmonia is found asymptotically due to the + meson channels in central collisions of at =
200 GeV which, however, is lower than the yield expected from binary
scaling of collisions.Comment: 42 pages, including 14 eps figures, discussions extended and
references added, to be published in Phys. Rev.
Macroscopic quantum superpositions in highly-excited strongly-interacting many-body systems
We demonstrate a break-down in the macroscopic (classical-like) dynamics of
wave-packets in complex microscopic and mesoscopic collisions. This break-down
manifests itself in coherent superpositions of the rotating clockwise and
anticlockwise wave-packets in the regime of strongly overlapping many-body
resonances of the highly-excited intermediate complex. These superpositions
involve many-body configurations so that their internal interactive
complexity dramatically exceeds all of those previously discussed and
experimentally realized. The interference fringes persist over a time-interval
much longer than the energy relaxation-redistribution time due to the
anomalously slow phase randomization (dephasing). Experimental verification of
the effect is proposed.Comment: Title changed, few changes in the abstract and in the main body of
the paper, and changes in the font size in the figure. Uses revTex4, 4 pages,
1 ps figur
Low energy and dynamical properties of a single hole in the t-Jz model
We review in details a recently proposed technique to extract information
about dynamical correlation functions of many-body hamiltonians with a few
Lanczos iterations and without the limitation of finite size. We apply this
technique to understand the low energy properties and the dynamical spectral
weight of a simple model describing the motion of a single hole in a quantum
antiferromagnet: the model in two spatial dimension and for a double
chain lattice. The simplicity of the model allows us a well controlled
numerical solution, especially for the two chain case. Contrary to previous
approximations we have found that the single hole ground state in the infinite
system is continuously connected with the Nagaoka fully polarized state for
. Analogously we have obtained an accurate determination of the
dynamical spectral weight relevant for photoemission experiments. For
an argument is given that the spectral weight vanishes at the Nagaoka energy
faster than any power law, as supported also by a clear numerical evidence. It
is also shown that spin charge decoupling is an exact property for a single
hole in the Bethe lattice but does not apply to the more realistic lattices
where the hole can describe closed loop paths.Comment: RevTex 3.0, 40 pages + 16 Figures in one file self-extracting, to
appear in Phys. Rev
Thermal maps and properties of comet 67P as derived from Rosetta/VIRTIS data
After a 10-year cruise, the Rosetta
spacecraft began a close exploration of its main target,
comet 67P/Churyumov-Gerasimenko, in July 2014.
Since then, the Visible InfraRed Thermal Imaging
Spectrometer (VIRTIS) acquired hyperspectral
images of the comet’s surface with an unprecedented
spatial resolution. VIRTIS data are routinely used to
map the surface composition and to retrieve surface
temperatures on the dayside of the comet.
The thermal behavior of the surface of comet 67P
is related to composition and physical properties that
provide information about the nature and evolution of
those materials.
Here we present temperature maps of comet 67P
that were observed by Rosetta under different illumination conditions and different local solar times
One particle spectral weight of the three dimensional single band Hubbard model
Dynamic properties of the three-dimensional single-band Hubbard model are
studied using Quantum Monte Carlo combined with the maximum entropy technique.
At half-filling, there is a clear gap in the density of states and well-defined
quasiparticle peaks at the top (bottom) of the lower (upper) Hubbard band. We
find an antiferromagnetically induced weight above the naive Fermi momentum.
Upon hole doping, the chemical potential moves to the top of the lower band
where a robust peak is observed. Results are compared with spin-density-wave
(SDW) mean-field and self consistent Born approximation results, and also with
the infinite dimensional Hubbard model, and experimental photoemission (PES)
for three dimensional transition-metal oxides.Comment: 11 pages, REVTeX, 16 figures included using psfig.sty. Ref.30
correcte
Determination of the Deep Inelastic Contribution to the Generalised Gerasimov-Drell-Hearn Integral for the Proton and Neutron
The virtual photon absorption cross section differences [sigma_1/2-sigma_3/2]
for the proton and neutron have been determined from measurements of polarised
cross section asymmetries in deep inelastic scattering of 27.5 GeV
longitudinally polarised positrons from polarised 1H and 3He internal gas
targets. The data were collected in the region above the nucleon resonances in
the kinematic range nu < 23.5 GeV and 0.8 GeV**2 < Q**2 < 12 GeV**2. For the
proton the contribution to the generalised Gerasimov-Drell-Hearn integral was
found to be substantial and must be included for an accurate determination of
the full integral. Furthermore the data are consistent with a QCD
next-to-leading order fit based on previous deep inelastic scattering data.
Therefore higher twist effects do not appear significant.Comment: 6 pages, 3 figures, 1 table, revte
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