116 research outputs found

    Barriers to Faith: An Annotated Bibliography

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    A review of the recent book publications related to the spring theme, Unity in Christ. We include the following titles. Anderson, Tawa J. Why Believe: Christian Apologetics for a Skeptical Age (Hobbs College Library), edited by Heath A. Thomas. Nashville: B&H Publishing Group. 2021. ISBN-13: 978-1087724232. 336 pages. 26.99.Bahnsen,GregL.ByThisStandard:TheAuthorityofGod2˘7sLawToday.MurrellsInlet,SouthCarolina:CovenantMediaPress,2020.ISBN13:9780998025216.275pages.26.99. Bahnsen, Greg L. By This Standard: The Authority of God\u27s Law Today. Murrell’s Inlet, South Carolina: Covenant Media Press, 2020. ISBN-13: 978-0998025216. 275 pages. 30.00. Bass, Justin W. The Bedrock of Christianity: The Unalterable Facts of Jesus\u27 Death and Resurrection. Bellingham, WA: Lexham Press, 2020. ISBN-13: 978-1683593607. 272 pages. 18.99.Enns,Peter.HowtheBibleActuallyWorks:inWhichIExplainHowanAncient,Ambiguous,andDiverseBookLeadsUstoWisdomRatherThanAnswersandWhyThatsGreatNews.Firstedition.SanFrancisco:HarperOne,2019.ISBN13:9780062686749.304pages.18.99. Enns, Peter. How the Bible Actually Works: in Which I Explain How an Ancient, Ambiguous, and Diverse Book Leads Us to Wisdom Rather Than Answers--and Why That’s Great News. First edition. San Francisco: HarperOne, 2019. ISBN-13: 978-0062686749. 304 pages. 15.99. Geisler, David and Norman Geisler. Conversational Evangelism: Connecting with People to Share Jesus. Eugene, OR: Harvest House Publishers. 2014. ISBN-13: ‎978-0736950831. 256 pages. 15.99.McFarland,Alex.The10MostCommonObjectionstoChristianity.Minneapolis,MN.BethanyHouse,2007.ISBN13:9780764215162.256pages.15.99. McFarland, Alex. The 10 Most Common Objections to Christianity. Minneapolis, MN. Bethany House, 2007. ISBN-13: 978-0764215162. 256 pages. 16.00. McLaughlin, Rebecca. Confronting Christianity: 12 Hard Questions for the World\u27s Largest Religion. Wheaton, IL: Crossway, 2019. ISBN-13: 978-1433564239. 240 pages. 24.99.Murphy,CaraL.T.TheInquisitiveChrist:12EngagingQuestions.Brentwood,TN:FaithWords.2020.ISBN13:9781546038375.288pages.24.99. Murphy, Cara L. T. The Inquisitive Christ: 12 Engaging Questions. Brentwood, TN: FaithWords. 2020. ISBN-13: 978-1546038375. 288 pages. 27.00. Strahan, Joshua Marshall. The Basics of Christian Belief: Bible, Theology, and Life\u27s Big Questions. Grand Rapids, MI: Baker Academic. 2020. ISBN-13: 978-1540962010. 240 pages. 49.99.Swain,ScottR.TheTrinity:AnIntroduction(ShortStudiesinSystematicTheology),editedbyGrahamA.ColeandOrenR.Martin.Wheaton,IL:Crossway,2020.ISBN13:9781433561214.160pages.49.99. Swain, Scott R. The Trinity: An Introduction (Short Studies in Systematic Theology), edited by Graham A. Cole and Oren R. Martin. Wheaton, IL: Crossway, 2020. ISBN-13: 978-1433561214. 160 pages. 15.99. Wright, N. T. Broken Signposts: How Christianity Makes Sense of the World. New York, NY: HarperOne. ISBN-13: 978-0062564092. 280 pages. 2020. $27.99

    Unity in Christ: An Annotated Bibliography

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    A review of the recent book publications related to the spring theme, Unity in Christ. We include the following titles. Alma, Hans et al. Moral and Spiritual Leadership in an Age of Plural Moralities. Anatolios, Khaled. Deification through the Cross: An Eastern Christian Theology of Salvation. Barrett, Matthew. Canon, Covenant and Christology: Rethinking Jesus and the Scriptures of Israel. Beck, William David and Mike Licona. Raised on the Third Day: Defending the Historicity of the Resurrection of Jesus. Chia, Edmund Kee-Fook. Confucianism and Christianity: Interreligious Dialogue on the Theology of Mission. Emerson, Matthew Y. He Descended to the Dead: An Evangelical Theology of Holy Saturday. Fairbairn, Donald, and Ryan M. Reeves. The Story of Creeds and Confessions: Tracing the Development of the Christian Faith. Farhadian, Charles E. Christianity: A Brief Introduction. Gallagher, Edmon L., and John D. Meade. The Biblical Canon Lists from Early Christianity: Texts and Analysis. Jipp, Joshua W. The Messianic Theology of the New Testament. Kaemingk, Matthew and Cory B. Willson. Work and Worship: Reconnecting Our Labor and Liturgy. Price, J. Randall. What Should We Think About Israel?: Separating Fact from Fiction in the Middle East Conflict. Wellum, Stephen J. The Person of Christ: An Introduction

    Ranking Objections to Christian Theism: A Survey of Subjective Declarations and their Correlations with Expert Opinions

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    There have been numerous books written on the top objections to Christianity—sometimes stated as “common,” “major,” “frequent,” “every day,” “cultural,” “tough,” “difficult” objections. However, there is a dearth of behavioral studies in the literature that show how and given population ranks objections to Christianity. As such, the apologist has had to rely on expert opinions from the books that have been authored. These expert opinions are based on familiarity with the literature in the field and contact with laity from university, church, and other speaking engagements. The purpose of this study is to document trends in how people report the relative strength of objections to Christian theism.[1] We analyze whether these trends correlate with popular works of Christian apologists—our baseline for expert opinion. Further, we determine whether there are any statistically significant relationships between reported demographics, rankings, and attitudes. Summary of Results and Analysis. Subjective declarations of respondents of the questionnaire showed that most participants were either 18-24 (marginally more than 55-64 and 65-74), male (marginally more than female), had some college (marginally more than bachelor’s, master’s degrees), lived in a suburban community, or lived in the South. In comparing the expert opinion baseline with the aggregate survey ranking results, we see similar rankings between the objection that “God is unloving/immoral” and that the “Bible is not inerrant” (ranked by both as 1st and 2nd, respectively) at the higher end of the spectrum. We found that those identified as agnostic seem to have the closest potential correlation to expert opinion (baseline). The mean of their rankings produced four objections that closely approximated the baseline, one objection that was about one rank removed from the baseline, and three objections that were about two ranks from the baseline. For demographics and rankings, we found statistically significant relationships between religious identification and the objection “God does not exist” with those who identified as atheists, giving it an average ranking of 3.74 (on a scale of 1-13; 1 = highest, 13 = lowest). For demographics and attitudes, we found statistically significant relationships between religious identification and age, religious discussion importance, and attitude toward Christian theism. (See “Analysis” section.) [1] The study was done under the School of Divinity Department at Liberty University in compliance with Liberty University’s Internal Review Board (Research Ethics Office). IRB-FY21-22-12. Policy: Post-2018 Rule. Submitted 07-06-2021. Last approved 09-07-2021, no expiration date applicable

    Probing the classical field approximation - thermodynamics and decaying vortices

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    We review our version of the classical field approximation to the dynamics of a finite temperature Bose gas. In the case of a periodic box potential, we investigate the role of the high momentum cut-off, essential in the method. In particular, we show that the cut-off going to infinity limit decribes the particle number going to infinity with the scattering length going to zero. In this weak interaction limit, the relative population of the condensate tends to unity. We also show that the cross-over energy, at which the probability distribution of the condensate occupation changes its character, grows with a growing scattering length. In the more physical case of the condensate in the harmonic trap we investigate the dissipative dynamics of a vortex. We compare the decay time and the velocities of the vortex with the available analytic estimates.Comment: 7 pages, 8 eps figures, submitted to J. Optics B for the proceedings of the "Atom Optics and Interferometry" Lunteren 2002 worksho

    Epithelial NEMO links innate immunity to chronic intestinal inflammation

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    Deregulation of intestinal immune responses seems to have a principal function in the pathogenesis of inflammatory bowel disease(1-4). The gut epithelium is critically involved in the maintenance of intestinal immune homeostasis-acting as a physical barrier separating luminal bacteria and immune cells, and also expressing antimicrobial peptides(3,5,6). However, the molecular mechanisms that control this function of gut epithelial cells are poorly understood. Here we show that the transcription factor NF kappa B, a master regulator of pro-inflammatory responses(7,8), functions in gut epithelial cells to control epithelial integrity and the interaction between the mucosal immune system and gut microflora. Intestinal epithelial-cell-specific inhibition of NF-kappa B through conditional ablation of NEMO ( also called I kappa B kinase-gamma ( IKK gamma)) or both IKK1 ( IKK alpha) and IKK2 ( IKK beta)-IKK subunits essential for NF-kappa B activation(7-9)-spontaneously caused severe chronic intestinal inflammation in mice. NF-kappa B deficiency led to apoptosis of colonic epithelial cells, impaired expression of antimicrobial peptides and translocation of bacteria into the mucosa. Concurrently, this epithelial defect triggered a chronic inflammatory response in the colon, initially dominated by innate immune cells but later also involving T lymphocytes. Deficiency of the gene encoding the adaptor protein MyD88 prevented the development of intestinal inflammation, demonstrating that Toll-like receptor activation by intestinal bacteria is essential for disease pathogenesis in this mouse model. Furthermore, NEMO deficiency sensitized epithelial cells to tumour-necrosis factor ( TNF)-induced apoptosis, whereas TNF receptor-1 inactivation inhibited intestinal inflammation, demonstrating that TNF receptor-1 signalling is crucial for disease induction. These findings demonstrate that a primary NF-kappa B signalling defect in intestinal epithelial cells disrupts immune homeostasis in the gastrointestinal tract, causing an inflammatory-bowel-disease-like phenotype. Our results identify NF-kappa B signalling in the gut epithelium as a critical regulator of epithelial integrity and intestinal immune homeostasis, and have important implications for understanding the mechanisms controlling the pathogenesis of human inflammatory bowel disease.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/62858/1/nature05698.pd

    Acceptability of financial incentives and penalties for encouraging uptake of healthy behaviours: focus groups

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    BACKGROUND: There is evidence that financial incentive interventions, which include both financial rewards and also penalties, are effective in encouraging healthy behaviours. However, concerns about the acceptability of such interventions remain. We report on focus groups with a cross-section of adults from North East England exploring their acceptance of financial incentive interventions for encouraging healthy behaviours amongst adults. Such information should help guide the design and development of acceptable, and effective, financial incentive interventions. METHODS: Eight focus groups with a total of 74 adults were conducted between November 2013 and January 2014 in Newcastle upon Tyne, UK. Focus groups lasted approximately 60 minutes and explored factors that made financial incentives acceptable and unacceptable to participants, together with discussions on preferred formats for financial incentives. Verbatim transcripts were thematically coded and analysed in Nvivo 10. RESULTS: Participants largely distrusted health promoting financial incentives, with a concern that individuals may abuse such schemes. There was, however, evidence that health promoting financial incentives may be more acceptable if they are fair to all recipients and members of the public; if they are closely monitored and evaluated; if they are shown to be effective and cost-effective; and if clear health education is provided alongside health promoting financial incentives. There was also a preference for positive rewards rather than negative penalties, and for shopping vouchers rather than cash incentives. CONCLUSIONS: This qualitative empirical research has highlighted clear suggestions on how to design health promoting financial incentives to maximise acceptability to the general public. It will also be important to determine the acceptability of health promoting financial incentives in a range of stakeholders, and in particular, those who fund such schemes, and policy-makers who are likely to be involved with the design, implementation and evaluation of health promoting financial incentive schemes. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12889-015-1409-y) contains supplementary material, which is available to authorized users

    A Survey of New Temperature-Sensitive, Embryonic-Lethal Mutations in C. elegans: 24 Alleles of Thirteen Genes

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    To study essential maternal gene requirements in the early C. elegans embryo, we have screened for temperature-sensitive, embryonic lethal mutations in an effort to bypass essential zygotic requirements for such genes during larval and adult germline development. With conditional alleles, multiple essential requirements can be examined by shifting at different times from the permissive temperature of 15°C to the restrictive temperature of 26°C. Here we describe 24 conditional mutations that affect 13 different loci and report the identity of the gene mutations responsible for the conditional lethality in 22 of the mutants. All but four are mis-sense mutations, with two mutations affecting splice sites, another creating an in-frame deletion, and one creating a premature stop codon. Almost all of the mis-sense mutations affect residues conserved in orthologs, and thus may be useful for engineering conditional mutations in other organisms. We find that 62% of the mutants display additional phenotypes when shifted to the restrictive temperature as L1 larvae, in addition to causing embryonic lethality after L4 upshifts. Remarkably, we also found that 13 out of the 24 mutations appear to be fast-acting, making them particularly useful for careful dissection of multiple essential requirements. Our findings highlight the value of C. elegans for identifying useful temperature-sensitive mutations in essential genes, and provide new insights into the requirements for some of the affected loci

    Improving ecosystem health in highly altered river basins: a generalized framework and its application to the Mississippi-Atchafalaya River Basin

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    Continued large-scale public investment in declining ecosystems depends on demonstrations of “success”. While the public conception of “success” often focuses on restoration to a pre-disturbance condition, the scientific community is more likely to measure success in terms of improved ecosystem health. Using a combination of literature review, workshops and expert solicitation we propose a generalized framework to improve ecosystem health in highly altered river basins by reducing ecosystem stressors, enhancing ecosystem processes and increasing ecosystem resilience. We illustrate the use of this framework in the Mississippi-Atchafalaya River Basin (MARB) of the central United States (U.S.), by (i) identifying key stressors related to human activities, and (ii) creating a conceptual ecosystem model relating those stressors to effects on ecosystem structure and processes. As a result of our analysis, we identify a set of landscape-level indicators of ecosystem health, emphasizing leading indicators of stressor removal (e.g., reduced anthropogenic nutrient inputs), increased ecosystem function (e.g., increased water storage in the landscape) and increased resilience (e.g., changes in the percentage of perennial vegetative cover). We suggest that by including these indicators, along with lagging indicators such as direct measurements of water quality, stakeholders will be better able to assess the effectiveness of management actions. For example, if both leading and lagging indicators show improvement over time, then management actions are on track to attain desired ecosystem condition. If, however, leading indicators are not improving or even declining, then fundamental challenges to ecosystem health remain to be addressed and failure to address these will ultimately lead to declines in lagging indicators such as water quality. Although our model and indicators are specific to the MARB, we believe that the generalized framework and the process of model and indicator development will be valuable in an array of altered river basins

    Disease-Toxicant Interactions in Manganese Exposed Huntington Disease Mice: Early Changes in Striatal Neuron Morphology and Dopamine Metabolism

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    YAC128 Huntington's disease (HD) transgenic mice accumulate less manganese (Mn) in the striatum relative to wild-type (WT) littermates. We hypothesized that Mn and mutant Huntingtin (HTT) would exhibit gene-environment interactions at the level of neurochemistry and neuronal morphology. Twelve-week-old WT and YAC128 mice were exposed to MnCl2-4H2O (50 mg/kg) on days 0, 3 and 6. Striatal medium spiny neuron (MSN) morphology, as well as levels of dopamine (DA) and its metabolites (which are known to be sensitive to Mn-exposure), were analyzed at 13 weeks (7 days from initial exposure) and 16 weeks (28 days from initial exposure). No genotype-dependent differences in MSN morphology were apparent at 13 weeks. But at 16 weeks, a genotype effect was observed in YAC128 mice, manifested by an absence of the wild-type age-dependent increase in dendritic length and branching complexity. In addition, genotype-exposure interaction effects were observed for dendritic complexity measures as a function of distance from the soma, where only YAC128 mice were sensitive to Mn exposure. Furthermore, striatal DA levels were unaltered at 13 weeks by genotype or Mn exposure, but at 16 weeks, both Mn exposure and the HD genotype were associated with quantitatively similar reductions in DA and its metabolites. Interestingly, Mn exposure of YAC128 mice did not further decrease DA or its metabolites versus YAC128 vehicle exposed or Mn exposed WT mice. Taken together, these results demonstrate Mn-HD disease-toxicant interactions at the onset of striatal dendritic neuropathology in YAC128 mice. Our results identify the earliest pathological change in striatum of YAC128 mice as being between 13 to 16 weeks. Finally, we show that mutant HTT suppresses some Mn-dependent changes, such as decreased DA levels, while it exacerbates others, such as dendritic pathology
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