The Rhetoric of Agitation and Control: Impact in Scholarly Works

The Rhetoric of Agitation and Control was first published in 1971 by Bowers and Ochs. The text was revised in 1993 adding Richard Jensen as an author and in 2010 adding David Schulz as the fourth author. This paper addresses impact of this text by examining the number of times the work has been referred to in other scholarly works from 1971 until September 2012 using Google Scholar as the database. Citations were analyzed to determine how many works cited The Rhetoric of Agitation and Control, what types of publications they were, the general theme of the scholarly work in which the reference was made, and how The Rhetoric of Agitation and Control has been used in scholarly works

John Carroll\u27s Department of Communication: Growth at a Small University

This article examines the Department of Communications at John Carroll University between 1984 and 1999. John Carroll is an independent, Catholic, coeducational university founded in 1886 by the Society of Jesus. It is located in University Heights, a suburb of Cleveland, Ohio. The Department of Communications is located in the Humanities division of the College of Arts and Sciences. Essential for the growth of the department has been a clear holistic philosophy that have been implemented in hiring, budget, curriculum and co-curricular decisions

Award Winning Communication Programs: Centrality or Confusion?

This article analyzes award winning communication programs. The winners of the Small College Interest Group\u27s Programs of Excellence Award provide directions for achieving centrality and the goals outlined by the National Communication Association Task Force on Advancing the Discipline. They have similar names, degrees and locations within their institutions and they favor a holistic department and curricula that are interdisciplinary with strong department anchors. Most have assessment programs in place to maintain this quality. In most cases, they have identified themselves with the mission of their institution through courses and goals. These programs can provide some guidelines for departments in schools of 5,000 or less undergraduates to use in conducting self evaluations to determine if their programs have centrality

Self-reported pregnancy exposures and placental DNA methylation in the MARBLES prospective autism sibling study.

Human placenta is a fetal-derived tissue that offers a unique sample of epigenetic and environmental exposures present in utero. In the MARBLES prospective pregnancy study of high-risk younger siblings of children with autism spectrum disorder (ASD), pregnancy and environmental factors collected by maternal interviews were examined as predictors of placental DNA methylation, including partially methylated domains (PMDs), an embryonic feature of the placental methylome. DNA methylation data from MethylC-seq analysis of 47 placentas of children clinically diagnosed at 3 years with ASD or typical development using standardized assessments were examined in relation to: child's gestational age, birth-weight, and diagnosis; maternal pre-pregnancy body mass index, smoking, education, parity, height, prenatal vitamin and folate intake; home ownership; pesticides professionally applied to lawns or gardens or inside homes, pet flea/tick pouches, collars, or soaps/shampoos used in the 3 months prior to or during pregnancy. Sequencing run, order, and coverage, and child race and sex were considered as potential confounders. Akaike information criterion was used to select the most parsimonious among candidate models. Final prediction models used sandwich estimators to produce homoscadisticity-robust estimates of the 95% confidence interval (CI) and P-values controlled the false discovery rate at 5%. The strongest, most robust associations were between pesticides professionally applied outside the home and higher average methylation over PMDs [0.45 (95% CI 0.17, 0.72), P = 0.03] and a reduced proportion of the genome in PMDs [-0.42 (95% CI - 0.67 to -0.17), P = 0.03]. Pesticide exposures could alter placental DNA methylation more than other factors

A tetraspecific VHH-based neutralizing antibody modifies disease outcome in three animal models of Clostridium difficile infection

Clostridium difficile infection (CDI), a leading cause of nosocomial infection, is a serious disease in North America, Europe, and Asia. CDI varies greatly from asymptomatic carriage to life-threatening diarrhea, toxic megacolon, and toxemia. The incidence of community-acquired infection has increased due to the emergence of hypervirulent antibiotic-resistant strains. These new strains contribute to the frequent occurrence of disease relapse, complicating treatment, increasing hospital stays, and increasing morbidity and mortality among patients. Therefore, it is critical to develop new therapeutic approaches that bypass the development of antimicrobial resistance and avoid disruption of gut microflora. Here, we describe the construction of a single heteromultimeric VHH-based neutralizing agent (VNA) that targets the two primary virulence factors of Clostridium difficile, toxins A (TcdA) and B (TcdB). Designated VNA2-Tcd, this agent has subnanomolar toxin neutralization potencies for both C. difficile toxins in cell assays. When given systemically by parenteral administration, VNA2-Tcd protected against CDI in gnotobiotic piglets and mice and to a lesser extent in hamsters. Protection from CDI was also observed in gnotobiotic piglets treated by gene therapy with an adenovirus that promoted the expression of VNA2-Tcd

WISEP J180026.60+013453.1: A Nearby Late L Dwarf Near the Galactic Plane

We report a nearby L7.5 dwarf discovered using the Preliminary Data Release of the Wide-field Infrared Survey Explorer (WISE) and the Two Micron All-Sky Survey (2MASS). WISEP J180026.60+013453.1 has a motion of 0.42 arcsec/yr and an estimated distance of 8.8 \pm 1.0 pc. With this distance, it currently ranks as the sixth closest known L dwarf, although a trigonometric parallax is needed to confirm this distance. It was previously overlooked because it lies near the Galactic Plane (b=12). As a relatively bright and nearby late L dwarf with normal near-infrared colors, W1800+0134 will serve as a benchmark for studies of cloud-related phenomena in cool substellar atmospheres.Comment: 12 pages, 2 figure, accepted to the Astronomical Journal (AJ