Compaction and cementation controls on reservoir quality in Buntsandstein red beds

Reservoir quality in fluvial siliciclastic rocks is variable. Permeability is influenced by micron-scale grain coatings or bedding style on the m-/km-scale. Outcrops allow the analysis of depositional environments and diagenesis, thus an investigation of reservoir quality controls. A process-oriented approach is used to understand variability in a meander deposit, compaction and cementation behavior of lithofacies types during burial and the discrepancy between porosity and permeability values

My church – my language?: Language attitudes and language policiy in South African church

This study examines the language attitudes of members of three (formerly) Afrikaans-speaking congregations of the multilingual Moravian Church in South Africa (MCSA) with regard to current language practices within the Church and their ideas for a future language policy. It is based on interviews held with members of these congregations, while concepts of identity serve as a theoretical framework. Through these, it is shown that the MCSA could neither pursue a monolingual nor a consistently multilingual language policy in order not to aggravate the identification of its members with the Church

The impact of artificial intelligence on decision-making in Venture Capital Firms

This exploratory study examines the opportunity of Artificial Intelligence in the decision-making process of Venture Capitals. Investors have to take decisions under uncertainty, time pressure and suffer from bias. This study investigates the potential of Artificial Intelligence to overcome these challenges and improve the process. The results are based on a qualitative analysis based on 12 interviews with Venture Capitals, AI Experts, and companies offering solutions for Venture Capitals as well as secondary data in form of academic articles and online magazines. The findings reveal that Artificial Intelligence is currently mostly implemented at the beginning of the decision-making process. The usage of Artificial Intelligence improves the process of making decisions by lowering uncertainty, bias and increasing productivity and efficiency. The interviews show that that AI can be implemented in every step in the decision-making process and presents the specific use cases. Furthermore, implementation challenges and implications for practice are outlined. By applying AI, Venture Capitals improve their decision-making process, which ultimately could have a positive impact on the return of their portfolio.Este estudo exploratório examina a oportunidade da Inteligência Artificial no processo de tomada de decisão das Capitais de Venture. Os investidores têm que tomar decisões sob incerteza, pressão de tempo e sofrer de parcialidade. Este estudo investiga o potencial da Inteligência Artificial para superar esses desafios e melhorar o processo. Os resultados são baseados em uma análise qualitativa baseada em 12 entrevistas com Venture Capitals, AI Experts e empresas oferecendo soluções para Venture Capitals, bem como dados secundários em forma de artigos acadêmicos e revistas on-line. Os resultados revelam que a Inteligência Artificial atualmente é implementada principalmente no início do processo de tomada de decisão. O uso da Inteligência Artificial melhora o processo de tomada de decisões, diminuindo a incerteza, o viés e aumentando a produtividade e a eficiência. As entrevistas mostram que a IA pode ser implementada em todas as etapas do processo de tomada de decisão e apresenta os casos de uso específicos. Além disso, desafios de implementação e implicações para a prática são delineados. Ao aplicar a inteligência artificial, as empresas de capital de risco melhoram seu processo de tomada de decisão, o que, em última instância, pode ter um impacto positivo no retorno de sua carteira

Compaction and cementation controls on reservoir quality in Buntsandstein red beds

Reservoir quality in fluvial siliciclastic rocks is variable. Permeability is influenced by micron-scale grain coatings or bedding style on the m-/km-scale. Outcrops allow the analysis of depositional environments and diagenesis, thus an investigation of reservoir quality controls. A process-oriented approach is used to understand variability in a meander deposit, compaction and cementation behavior of lithofacies types during burial and the discrepancy between porosity and permeability values

Beruf und Familie vereinbar? Auf familienfreundliche Arbeitszeiten und ein gutes Betriebsklima kommt es an

Wir haben mithilfe einer logistischen Regression die Einflussfaktoren auf die Einschätzung der Vereinbarkeit der Arbeitszeiten mit der Familie sowie die Bewertung der Familienfreundlichkeit des Betriebes untersucht. Im Abschnitt 2 werden der Forschungsstand und die zu prüfenden Hypothesen dargestellt. Anschließend werden die Methode und die Variablen der Befragung erläutert. Abschnitt 4 präsentiert zuerst die bivariaten und anschließend die multivariaten empirischen Ergebnisse. Zum Schluss werden die Ergebnisse zusammengefasst und ein Fazit gezogen. --

Fumarate hydratase in cancer: A multifaceted tumour suppressor.

Cancer is now considered a multifactorial disorder with different aetiologies and outcomes. Yet, all cancers share some common molecular features. Among these, the reprogramming of cellular metabolism has emerged as a key player in tumour initiation and progression. The finding that metabolic enzymes such as fumarate hydratase (FH), succinate dehydrogenase (SDH) and isocitrate dehydrogenase (IDH), when mutated, cause cancer suggested that metabolic dysregulation is not only a consequence of oncogenic transformation but that it can act as cancer driver. However, the mechanisms underpinning the link between metabolic dysregulation and cancer remain only partially understood. In this review we discuss the role of FH loss in tumorigenesis, focusing on the role of fumarate as a key activator of a variety of oncogenic cascades. We also discuss how these alterations are integrated and converge towards common biological processes. This review highlights the complexity of the signals elicited by FH loss, describes that fumarate can act as a bona fide oncogenic event, and provides a compelling hypothesis of the stepwise neoplastic progression after FH loss.MS and CF are funded by an MRC Core Funding to the MRC Cancer Unit MRC_MC_UU_12022/6, CS is funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 722605

Lateral variations of detrital, authigenic and petrophysical properties in an outcrop analog of the fluvial Plattensandstein, Lower Triassic, Central S-Germany

The lateral heterogeneity of reservoir rocks is important to assess storage potential and permeability. This case study focusses on a Lower Triassic (upper Olenekian) outcrop of fluvial sandstones of the Plattensandstein Member (Röt Formation) near Röttbach in the southern part of the Germanic Basin, southern Germany. The Buntsandstein Group is considered a suitable reservoir for thermal storage or exploration in southern Germany. In the Röttbach Quarry, the >10 m thick lithic arkoses are exposed over 35 m laterally in three adjacent walls and consist of two units separated by an erosive surface. They are covered by several metres of the Lower Röt Claystone Member. Using sedimentological logging, spectral gamma ray-, porosity- and permeability measurements as well as petrographic analyses calculating compaction parameters, lateral reservoir quality differences are studied. Sedimentary structures in the multi-storey channels suggest a point bar deposit. The migration direction of the channels correlates with deteriorating reservoir quality. This reduction in porosity and permeability correlates with an increased detrital mica and authigenic illite content, the occurrence of rip-up clasts and a lateral increase of gamma ray signatures by 19 API (avg. 5.0 vol% K, 2.7 ppm U, 11.9 ppm Th). The occurrence of larger amounts of mica and clay minerals is linked to decreasing flow velocities throughout the evolution of a meandering system. They enhance compaction and reduce available intergranular pore space. Permeability laterally deteriorates by up to three orders of magnitude (48 to 0.02 mD, avg. 9 mD) while measured porosities show minor variability (11 to 19 %, avg. 16 %). The deterioration of reservoir quality is related to compactional (COPL 11 to 28 %, avg. 18 %) and cementational porosity loss (CEPL 13 to 29 %, avg. 22 %) and is mainly controlled by detrital mica and authigenic illite

Cervical spine metastases: techniques for anterior reconstruction and stabilization

pre-printThe surgical management of cervical spine metastases continues to evolve and improve. The authors provide an overview of the various techniques for anterior reconstruction and stabilization of the subaxial cervical spine after corpectomy for spinal metastases. Vertebral body reconstruction can be accomplished using a variety of materials such as bone autograft/allograft, polymethylmethacrylate, interbody spacers, and/or cages with or without supplemental anterior cervical plating. In some instances, posterior instrumentation is needed for additional stabilization