DEM Simulation of Concrete Fracture Phenomena

Concrete fracture phenomena are investigated in this work. It is the fracture processes and failure mechanisms which are specifically investigated rather than the reaching of a certain maximum load or the investigation of the concrete’s behaviour within a range of safe working loads. The following questions are addressed. How do the crack positions vary from one test to another? Is it possible to identify in advance where for example micro-cracks will emerge to a global macro-crack later on? In order to investigate this matter, a two-dimensional numerical simulation based on the Discrete Element Method (DEM) is used for the analysis of concrete behaviour under compression load. Frictional behaviour, crack initiation and damage evolution are analysed. Regarding the concrete body, convex and concave geometries can be treated. The cracks are discrete just as in real laboratory experiments. The cracks arise due to the interaction of the concrete particle elements and without the predefinition of any crack zones or crack elements. The simulation results are compared to the ones of laboratory experiments. The ratio of longitudinal strain to lateral strain is obtained as a result of the simulation and compared to experimental results. The qualitative evolution of postprocessing entities such as stresses and strains is analysed

German and Italian Users of Web-Accessed Genetic Data: Attitudes on Personal Utility and Personal Sharing Preferences. Results of a Comparative Survey (n=192)

Genetic information is increasingly provided outside of the traditional clinical setting, allowing users to access it directly via specialized online platforms. This development is possibly resulting in changing ethical and social challenges for users of predictive genetic tests. Little is known about the attitudes and experiences of users of web-accessed genetic information. This survey analyzes data from two European countries with regard to the utility of genetic information, the users\u2019 ways of making use of and dealing with information, and their sharing behavior. Particular focus is given to ethical and social questions regarding the motivation to share personal genetic results with others. Social factors tested for are national background, gender, and marital, parental, and educational status. This study will contribute to public discourse and offer ethical recommendations. The study will also serve to validate the developed questionnaire for use in population representative surveys

Guilt is effectively induced by a written auto-biographical essay but not reduced by experimental pain.

Introduction The aim of the present study was (1) to validate the method of guilt-induction by means of a written auto-biographical essay and (2) to test whether experimental pain is apt to alleviate the mental burden of guilt, a concept receiving support from both empirical research and clinical observation. Methods Three independent groups of healthy male participants were recruited. Group allocation was not randomized but within group pain/sham administration was counterbalanced over the two test-days. Groups were tested in the following consecutive order: Group A: guilt induction, heat-pain/sham, N = 59; Group B: guilt induction, cold-pressure-pain/sham, N = 43; Group C: emotionally neutral induction, heat-pain/sham, N = 39. Guilt was induced on both test-days in group A and B before pain/sham administration. Visual analog scale (VAS) guilt ratings immediately after pain/sham stimulation served as the primary outcome. In a control group C the identical heat-pain experiment was performed like in group A but a neutral emotional state was induced. Results A consistently strong overall effect of guilt-induction (heat-pain: p < 0.001, effect size r = 0.71; CPT-pain p < 0.001, r = 0.67) was found when compared to the control-condition (p = 0.25, r = 0.08). As expected, heat- and cold-pressure-stimuli were highly painful in all groups (p < 0.0001, r = 0.89). However, previous research supporting the hypothesis that pain is apt to reduce guilt was not replicated. Conclusion Although guilt-induction was highly effective on both test-days no impact of pain on behavioral guilt-ratings in healthy individuals could be identified. Guilt induction per se did not depend on the order of testing. The result questions previous experimental work on the impact of pain on moral emotions

Diversity and uniformity in genetic responsibility: moral attitudes of patients, relatives and lay people in Germany and Israel

The professional and institutional responsibility for handling genetic knowledge is well discussed; less attention has been paid to how lay people and particularly people who are affected by genetic diseases perceive and frame such responsibilities. In this exploratory study we qualitatively examine the attitudes of lay people, patients and relatives of patients in Germany and Israel towards genetic testing. These attitudes are further examined in the national context of Germany and Israel, which represent opposite regulatory approaches and bioethical debates concerning genetic testing. Three major themes of responsibility emerged from the inter-group and cross-cultural comparison: self-responsibility, responsibility for kin, and responsibility of society towards its members. National contrast was apparent in the moral reasoning of lay respondents concerning, for example, the right not to know versus the duty to know (self-responsibility) and the moral conflict concerning informing kin versus the moral duty to inform (responsibility for kin). Attitudes of respondents affected by genetic diseases were, however, rather similar in both countries. We conclude by discussing how moral discourses of responsibility are embedded within cultural (national, religious) as well as phenomenological (being affected) narratives, and the role of public engagement in bioethical discourse

Performance evaluation of a waste-heat driven adsorption system for automotive air-conditioning: Part I - Modeling and experimental validation

[EN] Adsorption systems driven by engine waste heat are one of the possible alternatives to the conventional automobile air conditioning in terms of energy savings and environmental issues. Assessment of this issue are carried in a two-part study. In this first part I, theoretical and experimental investigations were performed on a two bed, silica gel adsorption chiller for automotive applications. A prototype adsorption system with a total weight of about 86 kg was developed and tested to driven by low-grade waste heat. The single adsorbent bed consisted of three plate-fin heat exchangers connected in parallel. An improved non-equilibrium lumped parameter model was developed to predict the transient performance of the system. The model is fully dynamic and takes into account the mass transfer resistance and pressure drop for each component of the system. The results showed that the model is able to accurately predict the dynamic performance of the system under different operating conditions and configuration modes with a short calculation time. The tested chiller was able to produce an average cooling capacity of about 2.1 kW with a COP of 0.35 at the rated operating conditions. Heat recovery system results in increasing the COP by 43% and the cooling power by 4%. (C) 2016 Elsevier Ltd. All rights reserved.This work has been partially supported by the European project TOPMACS-Thermally Operated Mobile Air-Conditioning Systems, funded by the European Comission under the 6th European Community framework program FP6-SUSTDEV - Sustainable Development, Global Change and Ecosystems: thematic priority 6 under the Focusing and Integrating Community Research programme 2002-2006. (Contract Ref. TST4-CT-2005-012471. The authors are very grateful to the Energy Research Center of Netherlands (ECN) for their support in the experimental work.Verde Trindade, M.; Harby Mohamed Abd Alaal, K.; De Boer, R.; Corberán, JM. (2016). Performance evaluation of a waste-heat driven adsorption system for automotive air-conditioning: Part I - Modeling and experimental validation. Energy. 116:526-538. doi:10.1016/j.energy.2016.09.113S52653811

Client Participation in Moral Case Deliberation: A Precarious Relational Balance

Moral case deliberation (MCD) is a form of clinical ethics support in which the ethicist as facilitator aims at supporting professionals with a structured moral inquiry into their moral issues from practice. Cases often affect clients, however, their inclusion in MCD is not common. Client participation often raises questions concerning conditions for equal collaboration and good dialogue. Despite these questions, there is little empirical research regarding client participation in clinical ethics support in general and in MCD in particular. This article aims at describing the experiences and processes of two MCD groups with client participation in a mental healthcare institution. A responsive evaluation was conducted examining stakeholders’ issues concerning client participation. Findings demonstrate that participation initially creates uneasiness. As routine builds up and client participants meet certain criteria, both clients and professionals start thinking beyond ‘us-them’ distinctions, and become more equal partners in dialogue. Still, sentiments of distrust and feelings of not being safe may reoccur. Client participation in MCD thus requires continuous reflection and alertness on relational dynamics and the quality of and conditions for dialogue. Participation puts the essentials of MCD (i.e., dialogue) to the test. Yet, the methodology and features of MCD offer an appropriate platform to introduce client participation in healthcare institutions