Índice de massa corporal de gestantes na unidade de saúde da família

Introduction: In Brazil, obesity is found in 25% to 30% of pregnancies. Objectives: To analyze the body mass index in the gestation of women attended at the Basic Health Unit; To identify the prevalence of overweight and obesity in pregnant women; To verify the gestational weight gain and to associate with the variables: age, marital status, gestational number, parity, pre-gestational weight and prenatalMethodology: Quantitative, retrospective and descriptive study comprising 241 women who had under gone to prenatal care, from 2013 to 2015. The Prevalence Coefficient (total number of overweight and obese pregnant women x 103/total number of pregnant women) was considered.Results: The prevalence coefficient of overweight and obesity was 34.54%, in 2013; in 2014, 43.61% and in 2015, 41.34%. According to obstetric characteristics, they had a strong correlation with the total weight gain of the gestation at prenatal consultations and at gestational age, with significance equal to P <0.0001. It was identified that the BMI of pregnant women ranged from 15.80 to 46.8 kg / m². Overweight was detected in 39.84% of pregnant women; of these 34.44% gained weight higher than the expected during gestation. While of the with overweight 55.00% gained more weight than recommended, and of those with obesity 54.77%. The correlation of pre-gestational BMI with the variables of the previous weight, the weight at the last consultation and the total weight gain during pregnancy was strong with the BMI, P <0.0001.Conclusion: Inadequate nutritional status has been increasing over the years, strengthening the importance of a more comprehensive approach on the subject with pregnant women.Introducción: En Brasil, la obesidad se encuentra en 25% a 30% de las gestantes. Objetivos: Analizar el índice de masa corporal en la gestación de mujeres atendidas en la Unidad Básica de Salud; Identificar la prevalencia de sobrepeso y obesidad en las gestantes; Verificar la ganancia de peso gestacional y asociar con las variables: edad, estado conyugal, número de gestación, paridad, peso pre-gestacional y prenatal Metodología: Estudio cuantitativo, retrospectivo y descriptivo. Compuesto por 241 mujeres que realizaron el prenatal, de 2013 a 2015. Fue considerado el Coeficiente de Prevalencia (número total de gestantes con sobrepeso y obesidad 103/número total de gestantes). Resultados: El coeficiente de prevalencia del sobrepeso y obesidad fue de 34,54%, en 2013; en 2014, de 43,61% y en 2015, de 41,34%. En las características obstétricas, tuvieron una fuerte correlación con el peso total ganado en la gestación las consultas prenatales y la edad gestacional, y relevancia igual a P<0,0001. Se identificó que el IMC de las gestantes varió de 15,80 a 46,80Kg/m². Se detecto que 39,84% de las gestantes pasaron del peso; 34,44% ganaron más peso que lo previsto en una gestación. De las con sobrepeso 55,00% ganaron más peso que lo recomendable y de las con obesidad 54,77%. Con respecto a la correlación del IMC pregestacional con los variables del peso previo, el peso en la última consulta y el aumento de peso total en la gestación fue intenso con el IMC, P<0,0001. Conclusión: El estado nutricional inadecuado se eleva con el paso de los años, reforzando la importancia de un abordaje más amplio acerca de la temática con las gestantes.Introdução: No Brasil, a obesidade é encontrada em 25% a 30% das gestações.Objetivos: Analisar o índice de massa corporal na gestação de mulheres atendidas na Unidade Básica de Saúde; Identificar a prevalência de sobrepeso e obesidade nas gestantes; Verificar o ganho de peso gestacional e associar com as variáveis: idade, estado conjugal, número de gestação, paridade, peso pré-gestacional e pré-natal.Metodologia: Estudo quantitativo, retrospectivo e descritivo. Composto por 241 mulheres que realizaram o pré-natal, de 2013 a 2015. Foi considerado o Coeficiente de Prevalência (número total de gestantes com sobrepeso e obesidadex 103/número total de gestantes). Resultados: O coeficiente de prevalência do sobrepeso e obesidade foi de 34,54%, em 2013; em 2014, de 43,61% e em 2015, de 41,34%. Nas características obstétricas, tiveram uma forte correlação com o ganho de peso total da gestação às consultas pré-natal e à idade gestacional, e significância igual a P<0,0001. Identificou-se que o IMC das gestantes variou de 15,80 a 46,80 Kg/m². Acima do peso detectou-se 39,84% das gestantes; 34,44% ganharam peso acima do esperado na gestação. Enquanto que das sobrepeso 55,00% ganharam peso mais do que o recomendado e das com obesidade 54,77%. A correlação do IMC pré-gestacional com as variáveis do peso anterior, o peso na última consulta e o ganho de peso total na gestação foi forte com o IMC, P<0,0001. Conclusão: O estado nutricional inadequado vem aumentando com o decorrer dos anos, reforçando a importância de uma abordagem mais ampla sobre o tema com as gestantes. &nbsp

Variabilidade Genética Em Populações De Rottboellia Cochinchinensis Na Cultura Da Cana-de-açúcar

The hypothesis assumed was the existence of biotypes within populations, which has been the cause of difficulties in itchgrass control by farmers. For that, the genetic variability of three populations of Rottboellia cochinchinensis in sugarcane fields in the state of São Paulo was investigated by using the Amplified Fragment Length Polymorphism (AFLP) technique. Six primers were used to obtain molecular characterization data. AFLP gels were analyzed based on marker presence (1) and absence (0). Using NTSYs (Numerical Taxonomy and Multivariate Analysis System) software, the genetic similarity was calculated by the Jaccard coefficient and, from that, a dendrogram was built through the UPGMA (Unweighted Pair Group Method Arithmetic averages) method, besides determining the isopolymorphic marks. The average genetic similarities seen in the region was 0.742 for Igarapava, 0.793 for Mococa and 0.808 for Piracicaba. Between regions it was 0.730 (Igarapava vs Mococa), 0.735 (Mococa vs Piracicaba) and 0.694 (Igarapava vs Piracicaba). In line with the dendrogram, it is possible to detect the formation of two groups, one with 8 plants from Igarapava and Mococa and the other with 21 plants from Igarapava, Mococa and Piracicaba, as well as the presence of 1 discriminant individual from Piracicaba. It can be concluded that the genetic similarity among itchgrass populations from the state of São Paulo was high (72%), which denotes that the difficulties in chemical management are not only due to different biotypes but also due to other characteristics linked to tolerance of the species to herbicides. However, biotype existence cannot be discarded because of the polymorphic marks generating 22% average genetic variability. © 2016, Sociedade Brasileira da Ciencia das Plantas Daninha. All rights reserved.34347548

Processing of Rosmarinus officinalis linne extract on spray and spouted bed dryers

This article presents an investigation of the potential of spray and spouted bed technology for the production of dried extracts of Rosmarinus officinalis Linné, popularly known as rosemary. The extractive solution was characterized by loss on drying, extractable matter and total phenolic and flavonoid compounds (chemical markers). The product was characterized by determination of loss on drying, size distribution, morphology, flow properties and thermal degradation and thermal behavior. The spray and spouted bed dryer performance were assessed through estimation of thermal efficiency, product accumulation and product recovery. The parameters studied were the inlet temperature of the spouting gas (80 and 150ºC) and the feed mass flow rate of concentrated extract relative to the evaporation capacity of the dryer, Ws/Wmax (15 to 75%). The atomizing air flow rate was maintained at 20 l/min with a pressure of 196.1 kPa. The spouting gas flow rate used in the drying runs was 40% higher than the gas flow under the condition of minimum spouting. The spray drying gas flow rate was fixed at 0.0118 kg/s. Under the conditions studied, performance in the spray and spouted bed drying of rosemary extract was poor, causing high degradation of the marker compounds (mainly the phenolic compounds). Thus, process improvements are required before use on an industrial scale.FAPESPCNPq - IM-INOFA

Archaeology and education : approaching the "excluded past" at Araraquara, São Paulo State, Brazil

Orientador: Pedro Paulo Abreu FunariTese (doutorado) - Universidade Estadual de Campinas, Instituto de Filosofia e Ciencias HumanasResumo: A presente pesquisa tem como objetivo principal a realização de investigações arqueológicas na região de Araraquara/SP e sua utilização em trabalhos de educação patrimonial. As pesquisas em discussão centram atenção na execução de projetos arqueológicos de levantamento e escavação com posterior análise de laboratório de materiais de sítios cerâmicos da região proposta para estudos. Foram escolhidas as bacias do médio Mogi-Guaçu (bacia do rio Pardo) e médio Jacaré-Guaçu (bacia do rio Tietê). O panorama arqueológico resultante das pesquisas de campo é comparado aos dados já existentes em trabalhos arqueológicos acadêmicos e de Arqueologia de Contrato conduzidos na região delimitada pelos rios Piracicaba, Tietê, Pardo e Paraná, historicamente conhecida como ¿campos de Araraquara¿. As fontes etno-históricas e etnográficas também foram analisadas e confrontadas com os resultados arqueológicos, com o intuito de ponderar sobre suas influências na construção da imagem do indígena no Estado de São Paulo, sua história e contribuição para a formação da identidade nacional. Por fim, a tese centrou atenção em temas de teoria arqueológica que busquem compreender alguns conceitos antropológicos utilizados pelos arqueólogos brasileiros no que toca aos sítios cerâmicos e a visão de monolitismo resultante da utilização a-crítica desses conceitosAbstract: The present research has as its main goal to do archaeological investigations in the region of Araraquara/SP and to use such investigations in works of heritage education. The research centered its attention in the accomplishment of archaeological works of survey and excavation, with the posterior laboratory analysis of ceramic sites materials from the proposed region of study. For the fieldwork, we selected the areas of the Middle Mogi-Guaçu basin (in the Rio Pardo basin) and the Middle Jacaré-Guaçu basin (in the Tietê River basin). We compared the resulting archaeological scenario gathered from the field research to the data already available from academic archaeological works and from Contract Archaeology accomplished in the region delimited by the rivers Piracicaba, Tietê, Pardo and Paraná, historically known as the ¿Araraquara fields¿. We also analyzed and confronted the ethno-historical and ethnographical sources with the archaeological findings, with the aim of reflecting about its influences in the construction of the image of the native in the State of São Paulo, as well as in his history and his contribution to the formation of the national identity. Finally, the work has centered attention in themes of archaeological theory that seeks to understand some anthropological concepts used by Brazilian archaeologists in relation to the ceramic sites and also to review the monolithic vision resulting from the a-critical usage of such conceptsDoutoradoHistoria CulturalDoutor em Históri

ALTERAÇÕES MORFOLÓGICAS E MORFOMÉTRICAS INDUZIDAS POR DI (2-ETIL) FTALATO (DEHP) EM PULMÃO E FÍGADO DE RATOS WISTAR.

O policloreto de vinila (PVC) é um plástico muito utilizado por ser compatível com vários plastificantes, como o DEHP ( di (2-etil) ftalato) que o torna mais flexível. Utilizou-se 50 ratos com 180g e 200g. No grupo 1: 10 animais não receberam nenhum tipo de substância. Nos grupos 2 e 3 com 20 animais em cada grupo receberam doses de óleo de milho (1 ml) e 2,85 mg / kg de peso corporal / dia DEPH dissolvido em 1 ml de óleo de milho por gavagem uma vez ao dia. Após 4 semanas os animais foram sacrificados e o fígado e pulmão, foram retirados para análise histopatológica. No fígado dos animais dos grupo 1e 2 observou-se um parênquima hepático normal, hepatócitos dispostos em arranjos cordonais com capilares sinusóides normais, presença de células de Kupffer, hepatócitos com núcleos normais, entretanto no grupo 2 observou-se núcleos binucleados. No grupo 3 encontrou-se no espaço porta uma proliferação de ductos biliares e presença de hepatócitos binucleares, megalócitos e capilares congestos. No pulmão do grupo 1 observou-se aspectos normais nas áreas da região alveolar e bronquiolar, septos interalveolares de aspecto normal com hemácias. No grupo 2 encontrou-se um discreto espessamento alveolar, mas com preservação da luz alveolar evidente congestão pulmonar. No grupo 3 observou-se uma hiperplasia de nódulos linfóides associados aos brônquios, grande área de infarto hemorrágico e acentuado espessamento de septos interalveolares. Conclui-se que foram constatadas alterações histopatológicas do grupo tratado e a preservação das características normais do grupo controle

Projeto Arqueologia E EducaÇÃo: Um Olhar Para O Passado Da RegiÃo De PoÇos De Caldas

O artigo tem como intuito apresentar as principais ações de Projeto de Pesquisa sobre Arqueologia e Educação Patrimonial realizado na região sudoeste de Minas Gerais. O projeto tem como finalidade realizar pesquisas arqueológicas em Poços de Caldas e adjacências. Busca-se, a partir de metodologias advindas dos pensamentos arqueológico e antropológico, discutir as possibilidades de apreender a formação multicultural das populações humanas que hoje vivem na área foco da pesquisa. A produção material humana de tempos pretéritos, da História à Pré-História, é foco de nosso interesse, na medida em que possibilita aos investigadores produzir discursos que questionem a visão de um passado monocultural e de uma evolução unilinear da sociedade.71(7)138-152Arqueologia PúblicaEducação PatrimonialMulticulturalism

T-cell therapy for EBV-associated nasopharyngeal carcinoma : preparative lymphodepleting chemotherapy does not improve clinical results

Background: We and others have demonstrated that adoptive cell therapy with Epstein-Barr virus (EBV)-specific autologous cytotoxic T lymphocytes (CTLs) may control disease progression in patients with EBV-associated nasopharyngeal carcinoma (NPC). With the aim of favoring in vivo T-cell expansion, we optimized our cell therapy approach by administering higher doses of EBV-specific CTLs, following lymphodepleting chemotherapy. Patients and methods: Eleven patients with EBV-related NPC in whom conventional treatment failed have been enrolled. Patients received nonmyeloablative lymphodepleting chemotherapy consisting of cyclophosphamide and fludarabine. Two doses of autologous EBV-specific CTLs were subsequently infused, 2 weeks apart. Study end points were feasibility and clinical outcome. Results: All patients enrolled completed the treatment and were assessable for analysis. The median dose of CTLs per infusion was 3.7 7 10 8. Therapy was well tolerated, with no severe adverse events ascribable to either chemotherapy or cell therapy. Disease control (defined as either tumor regression or disease stabilization lasting >4 months) was obtained in 6 of 11 patients, in keeping with previously published results. Conclusions: Our data confirm that EBV-specific CTL therapy is safe and associated with antitumor activity in patients with advanced NPC. The use of lymphodepleting chemotherapy before high-dose CTL infusion did not enhance the clinical benefit observed in our previous series

Contrast-Induced Acute Kidney Injury and Endothelial Dysfunction: The Role of Vascular and Biochemical Parameters

Introduction: Contrast-induced acute kidney injury (CIAKI) is one of the main causes of acute renal failure in hospitalized patients, following the administration of iodinated contrast medium used for CT scans and angiographic procedures. CIAKI determines a high cardiovascular risk and appears to be one of the most feared complications of coronary angiography, causing a notable worsening of the prognosis with high morbidity and mortality. Aim: To evaluate a possible association between the renal resistive index (RRI) and the development of CIAKI, as well as an association with the main subclinical markers of atherosclerosis and the main cardiovascular risk factors. Materials and Methods: We enrolled 101 patients with an indication for coronary angiography. Patients underwent an assessment of renal function (serum nitrogen and basal creatinine, 48 and 72 h after administration of contrast medium), inflammation (C reactive protein (CRP), serum calcium and phosphorus, intact parathormone (iPTH), 25-hydroxyvitaminD (25-OH-VitD), serum uric acid (SUA), total cholesterol, serum triglycerides, serum glucose and insulin). All patients also carried out an evaluation of RRI, intima-media thickness (IMT), interventricular septum (IVS) and the ankle-brachial index (ABI). Results: 101 patients (68 male), with a mean age of 73.0 ± 15.0 years, were enrolled for the study; 35 are affected by type 2 diabetes mellitus. A total of 19 cases of CIAKI were reported (19%), while among diabetic patients we reported an incidence of 23% (8 patients). In our study, patients with CIAKI had significantly higher RRI (p < 0.001) and IMT (p < 0.001) with respect to the patients who did not develop CIAKI. Furthermore, patients with CIAKI had significantly higher CRP (p < 0.001) and SUA (p < 0.006). Conclusions: We showed a significant difference in RRI, IMT, SUA and CRP values between the population developing CIAKI and patients without CIAKI. This data appears relevant considering that RRI and IMT are low-cost, non-invasive and easily reproducible markers of endothelial dysfunction and atherosclerosis