Non-monotonic Overpressure vs. H2 Concentration Behavoiur during Vented Deflagration. Experimental Results

In industrial buildings explosion relief panels or doors are often used to reduce damages caused by gas explosion. Decades of research produced a significant contribution to the understanding of the phenomena aiming at establish an effective method by which the explosive overpressure could be reliably predicted. All the methods predict a monotonic increase of the overpressure with the concentration of the gas in the range from the lower explosion limit to the stoichiometric one. Nevertheless in few cases a non-monotonic behaviour of the maximum developed pressure as a function of hydrogen concentration was reported in the literature. The non-monotonic behaviour was also observed during experimental tests performed at the Scalbatraio laboratory at the University of Pisa, in a 25m 3 vented combustion test facility, with a vent area of 1,12m 2 . This paper is aimed to present the results obtained during the tests and to investigate the possible explanation of the phenomenon

Long-term renal function and hypertension in adult survivors of childhood sarcoma

Aim: Little data is available on long-term renal impairment in survivors from childhood sarcoma. We investigated the prevalence of renal impairment and hypertension after very long-term follow-up in survivors who reached adulthood after treatment for childhood sarcoma. Methods. A cross-sectional single center study was performed. Outcomes included estimating glomerular filtration rate (eGFR), albuminuria, glycosuria, serum phosphate and magnesium, tubular reabsorption phosphate (TRP), chronic kidney disease (CKD) according to the “Kidney Disease: Improving Global Outcomes” (KDIGO) guidelines and blood pressure (BP). Results: Out of 87>5-year sarcoma survivors, 30 adults (10F/20M, median age at diagnosis 9 years, median age at investigation 26 years, median follow-up 16 years, mean 19 years) were identified. Renal impairment was detected in 4 cases (13.3%); 3 of these fulfilled the criteria for CKD. Among the adult survivors, a subgroup of 15 cases (50%) had received ifosfamide without confounding factors such as a diagnosis of genito-urinary rhabdomyosarcoma or administration of other potentially nephrotoxic chemotherapy (platinum-based drugs or methotrexate); no renal dysfunction was detected in this subgroup. In the whole cohort of sarcoma survivors, hypertension was diagnosed in 4 cases (13.3%); BP was significantly correlated with body mass index [p 0.014] Conclusion: In our series of adult survivors treated for a diagnosis of sarcoma in their childhood, the prevalence of CKD was 10%. We found survivors treated with ifosfamide as the only nephrotoxic agent did not present glomerular or tubular toxicity at long term follow-up, but further studies including a larger number of cases are required to confirm it.

Propranolol as first-line treatment for life-threatening diffuse infantile hepatic hemangioma: a case report

[No abstract available

Analysis of Acoustic Pressure Oscillation During Vented Deflagration

In industrial buildings explosion relief panels or doors are often used to reduce damages caused by gas explosion. Decades of research produced a significant contribution to the understanding of the phenomena involved, nevertheless, among the aspects that need further research, interaction between acoustic oscillation and the flame front is one of the more important. Interaction between the flame front and acoustic oscillation has raised technical problem in lots of combustion applications as well, and had been studied theoretically and experimentally in such cases. Pressure oscillation had been observed in vented deflagration and in certain cases they are responsible for the highest pressure peak generated during the event. At Scalbatraio laboratory of Pisa University CVE test facility was built in order to investigate vented hydrogen deflagration. This paper is aimed to present an overview of the results obtained during several experimental campaigns which tests are analysed with the focus on the investigation of flame acoustic interaction phenomenon. Qualitative and quantitative analysis is presented and the possible physic generating the phenomenon investigated

Non-homogeneous hydrogen deflagrations in small scale enclosure. Experimental results

Abstract University of Pisa performed hydrogen releases and deflagrations in a 1.14 m3 test facility, which shape and dimensions resemble a gas cabinet. Tests were performed for the HySEA project, founded by the Fuel Cells and Hydrogen 2 Joint Undertaking with the aim to conduct pre-normative research on vented deflagrations in enclosures and containers used for hydrogen energy applications. The test facility, named Small Scale Enclosure (SSE), has a vent area of 0,42 m2 which can host different types of vent; plastic sheet and commercial vent were tested. Realistic levels of congestion are obtained placing a number of gas bottles inside the enclosure. Releases are performed from a buffer tank of a known volume filled with hydrogen at a pressure ranging between 15 and 60 bar. Two nozzles of different diameter and three different release directions were tested, being the nozzle placed at a height where in a real application a leak has the highest probability to occur. Three different ignition locations were investigated as well. This paper is aimed to summarize the main features of the experimental campaign as well as to present its results

HOMOGENEOUS HYDROGEN DEFLAGRATIONS IN SMALL SCALE ENCLOSURE. EXPERIMENTAL RESULTS

University of Pisa performed experimental tests in a 1 m3 facility, which shape and dimensions resemble a gas cabinet, for the HySEA project, founded by the Fuel Cells and Hydrogen 2 Joint Undertaking with the aim to conduct pre-normative research on vented deflagrations in real-life enclosures and containers used for hydrogen energy applications, in order to generate experimental data of high quality. The test facility, named Small Scale Enclosure (SSE), had a vent area of 0,42 m2 which location could be varied, namely on the top or in front of the facility, while different types of vent were investigated. Three different ignition location were investigated as well, and the range of Hydrogen concentration ranged between 10 and 18% vol. This paper is aimed to summarize the main characteristics of the experimental campaign as well as to present its results

Surgical treatment of retrosternal extraosseous Ewing Sarcoma in a 6-years old female: a clamshell approach with hemysternectomy and application of a non-crosslinked extracellular matrix

Background Ewing Sarcoma (ES) and Neuroblastoma (NB) belong to a family of tumours of primitive neuroectodermal origin (PNET) that occurs in both bone and soft tissue. Notwithstanding ES and NB are two distinct malignant tumours, sometimes there could be a link between them. Case report We describe a case of an extraosseous ES localized in the retrosternal region and the upper lobe of the right lung, which had been previously treated for NB in a 6 years old female. We treated this case with a clamshell approach which allows, in a one-step surgery, a complete excision of the mass reconstructing the hemysternectomy with a non-crosslinked matrix. Conclusion the clamshell approach is therefore useful to achieve the retrosternal space and the lung with a single surgical access. According to our experience, we consider appropriate to use a non-crosslinked matrix for sternal reconstruction

ETHNOECOLOGY OF Mussismilia braziliensis (Verrill 1868) IN THE MUNICIPALITY OF CARAVELAS, BAHIA, BRAZIL

This work is the first record of the perception of fishers and artisanal fishers in the Caravela city- Bahia and its respective districts (Ponta de Areia and Barra de Caravelas) regarding the species Mussismilia braziliensis, its ethnozoological aspects and its socio-environmental importance. The main objective is to associate the knowledge of these artisanal fishers about this species with the ethnoconservation of the Abrolhos Marine National Park (PARNAM-Abrolhos). Data collection was conducted from March to August 2019 through semi-structured interviews with 14 fishers from each fishing communities (Caravelas, Ponta de Areia and Barra de Caravelas). An ethno-mapping was carried out with two focal groups in order to know if the fishing grounds have received their names due to the presence or absence of corals. Using morphological characteristics, the focus species is grouped together with other corals belonging to different families, which are all considered to be brain corals. Other studies are recommended to appreciate the knowledge of the Caravelas fishers and use it for future environmental education, management and conservation projects of the PARNAM-Abrolhos