Optimizing single-photon-source heralding efficiency at 1550 nm using periodically poled lithium niobate

We explore the feasibility of using high conversion-efficiency periodically-poled crystals to produce photon pairs for photon-counting detector calibrations at 1550 nm. The goal is the development of an appropriate parametric down-conversion (PDC) source at telecom wavelengths meeting the requirements of high-efficiency pair production and collection in single spectral and spatial modes (single-mode fibers). We propose a protocol to optimize the photon collection, noise levels and the uncertainty evaluation. This study ties together the results of our efforts to model the single-mode heralding efficiency of a two-photon PDC source and to estimate the heralding uncertainty of such a source.Comment: 14 pages, 2 tables and 3 figures, final version accepted by Metrologi

Pacientes com transtornos relacionados ao uso de substâncias psicoativas atendidos em uma unidade de emergência psiquiátrica

Study type: Prevalence study. Objective: To describe the socio demographic and clinical profile of patients with mental and behavioral disorders due to psychoactive substance (PAS) use, evaluated by the Psychiatric team of the Referenced Emergency Unit (REU) at the State University Clinical Hospital of Campinas (UNICAMP-HC). Methods and casuistic: This is a descriptive and quantitative study, which analyzed patients with mental and behavioral disorders due to PAS use, evaluated by the Psychiatric team of the REU-HC-UNICAMP during a period of 12 months, starting on May 2010. Results: There were evaluated 350 patients with PAS related disorders, representing 23.8% of those who sought psychiatric care. Most were males and younger than other patients of the emergency unit. The main reason for seeking help was psychiatric complaint other than PAS related disorders (23.1%), followed by desire to be treated oneself/being admitted to inpatient psychiatric treatment (20.8%) and intoxication (12.5%); 38.5% had a diagnosis of multiple PAS dependence and 34.8% were diagnosed with isolated alcohol dependence; 36% had psychiatric comorbidities and, when compared to other patients, they received more medications during attendance and were less directed to primary care units. Conclusion: There is a high rate of consultations of patients with PAS related problems in the psychiatric emergency unit. Data on the profile of the evaluated these patients can contribute to the improvement of care to this populationModelo do Estudo: Estudo de prevalência. Objetivo: Descrever o perfil sócio demográfico e clínico de pacientes com transtornos relacionados ao uso de substâncias psicoativas (SPA) atendidos pela Psiquiatria da Unidade de Emergência Referenciada (UER) do Hospital de Clínicas (HC) da UNICAMP. Métodos e casuística: Estudo descritivo e quantitativo, que avaliou os pacientes com transtornos relacionados ao uso de SPA atendidos pela Psiquiatria da UER do HC-UNICAMP no período de 12 meses a partir de maio de 2010. Resultados: Foram avaliados 350 pacientes com transtornos por uso de SPA, representando 23.8% do total dos que procuraram atendimento psiquiátrico. Maioria do sexo masculino e mais jovens do que os demais pacientes. O principal motivo de atendimento foi queixa psiquiátrica outra que não o uso de SPA (23,1%), seguido do desejo de se tratar/internar (20,8%) e intoxicação (12,5%). 38,5% tinham diagnóstico de dependência de múltiplas SPA e 34,8% dependência exclusiva de álcool; 36% apresentavam comorbidade psiquiátrica. Quando comparados com os demais pacientes avaliados pela Psiquiatria, receberam mais medicações no atendimento e foram menos encaminhados à atenção primária. Conclusão: Há elevada taxa de atendimento de pessoas com problemas relacionados ao uso de SPA na emergência psiquiátrica. Dados sobre o perfil dos atendidos podem contribuir para a melhoria da assistência a esta populaçã

High-throughput genotyping of resilient tomato landraces to detect candidate genes involved in the response to high temperatures

The selection of tolerant varieties is a powerful strategy to ensure highly stable yield under elevated temperatures. In this paper, we report the phenotypic and genotypic characterization of 10 tomato landraces to identify the best performing under high temperatures. The phenotyping of five yield-related traits allowed us to select one genotype that exhibits highly stable yield performances in different environmental conditions. Moreover, a Genotyping-by-Sequencing approach allowed us to explore the genetic variability of the tested genotypes. The high and stable yielding landrace E42 was the most polymorphic one, with ~49% and ~47% private SNPs and InDels, respectively. The effect of 26,113 mutations on proteins’ structure was investigated and it was discovered that 37 had a high impact on the structure of 34 proteins of which some are putatively involved in responses to high temperatures. Additionally, 129 polymorphic sequences aligned against tomato wild species genomes revealed the presence in the genotype E42 of several introgressed regions deriving from S. pimpinellifolium. The position on the tomato map of genes affected by moderate and high impact mutations was also compared with that of known markers/QTLs (Quantitative Trait Loci) associated with reproductive and yield-related traits. The candidate genes/QTLs regulating heat tolerance in the selected landrace E42 could be further investigated to better understand the genetic mechanisms controlling traits for high and stable yield trait under high temperatures

The Use of a Plant-Based Biostimulant Improves Plant Performances and Fruit Quality in Tomato Plants Grown at Elevated Temperatures.

Abiotic stresses can cause a substantial decline in fruit quality due to negative impacts on plant growth, physiology and reproduction. The objective of this study was to verify if the use of a biostimulant based on plant and yeast extracts, rich in amino acids and that contains microelements (boron, zinc and manganese) can ensure good crop yield and quality in tomato plants grown at elevated temperatures (up to 42 C). We investigated physiological responses of four di↵erent tomato landraces that were cultivated under plastic tunnel and treated with the biostimulant CycoFlow. The application of the biostimulant stimulated growth (plants up to 48.5% taller) and number of fruits (up to 105.3%). In plants treated with the biostimulant, antioxidants contents were higher compared to non-treated plants, both in leaves and in fruits. In particular, the content of ascorbic acid increased after treatments with CycoFlow. For almost all the traits studied, the e↵ect of the biostimulant depended on the genotype it was applied on. Altogether, the use of the biostimulant on tomato plants led to better plant performances at elevated temperatures, that could be attributed also to a stronger antioxidant defence system, and to a better fruit nutritional quality

Turning a Digital Camera into an Absolute 2D Tele-Colorimeter

We present a simple and effective technique for absolute colorimetric camera characterization, invariant to changes in exposure/aperture and scene irradiance, suitable in a wide range of applications including image-based reflectance measurements, spectral pre-filtering and spectral upsampling for rendering, to improve colour accuracy in high dynamic range imaging. Our method requires a limited number of acquisitions, an off-the-shelf target and a commonly available projector, used as a controllable light source, other than the reflected radiance to be known. The characterized camera can be effectively used as a 2D tele-colorimeter, providing the user with an accurate estimate of the distribution of luminance and chromaticity in a scene, without requiring explicit knowledge of the incident lighting power spectra. We validate the approach by comparing our estimated absolute tristimulus values (XYZ data in cd/m 2 ) with the measurements of a professional 2D tele-colorimeter, for a set of scenes with complex geometry, spatially varying reflectance and light sources with very different spectral power distribution

Intratidal variability and transport of petroleum aromatic hydrocarbons in an anthropized tropical estuarine system: the Suape estuary (8.4S 35W)

A instalação do Complexo Industrial Portuário de Suape (CIPS) modificou algumas características físicas, químicas e biológicas do Estuário de Suape. Este estudo apresenta a primeira caracterização física deste sistema, focando na hidrodinâmica local, transporte de materiais e a influência destes sobre algumas propriedades locais. Os parâmetros físicos também foram associados aos hidrocarbonetos de petróleo dissolvidos e/ou dispersos (HPDDs). Durante um ciclo completo de maré (13 h), foram registrados o nível, fluxo e propriedades da água (salinidade, temperatura, material em suspensão - MS -, clorofila e oxigênio dissolvido), além da velocidade e direção das correntes, usando ADCP e CTD. Os HPDDs foram investigados nas águas superficiais e de fundo, através de espectrofluorescência. Os resultados revelaram uma estrutura vertical homogênea, um regime de maré semidiurno e um padrão térmico diurno. As concentrações de HPDDs na superfície e no fundo são baixas e similares, devido à ação da maré. A fonte mais provável é o CIPS, uma vez que o transporte residual dos hidrocarbonetos de petróleo, da clorofila e do oxigênio dissolvido são no sentido do estuário do Massangana. Um padrão oposto foi observado para o transporte residual da salinidade e MS, no sentido da lagoa. Estes resultados indicam que a hidrodinâmica local é essencial para entender o transporte e troca de materiais entre os vários segmentos do estuário. Estudos mais completos são necessários para se obter conclusões mais consistentes.The Suape Estuary encompasses the Suape Industrial Port Complex (SIPC), a major industrial development in Brazil's Northeast region, which, in order to be implanted, caused drastic environmental changes in this system. This study presents the first physical characterization of the Suape estuarine system, focusing on the local hydrodynamics, material transport and its influence on some specific properties. Physical properties were also associated to dissolved dispersed petroleum hydrocarbons (DDPHs). A study was undertaken during a complete semi-diurnal tidal cycle (13 hr), during which water level, water flow, current velocity and direction, water properties (salinity, temperature, suspended particulate matter - SPM -, chlorophyll and dissolved oxygen) were recorded using ADCP and CTD systems. The DDPHs were investigated in surface and bottom waters, by spectrofluorescence, using Carmópolis oil and chrysene as analytical standards. Results showed a well-mixed vertical structure, a semi-diurnal tide regime and a diurnal thermal pattern. There was no statistical difference between DDPH concentrations at surface and bottom, due to the tide acting as an important homogenizer. DDPHs were low and the main contribution seems to be that from SIPC, as the residual transport of DDPHs, chlorophyll and dissolved oxygen, was towards the Massangana estuary. An opposite pattern was observed for salinity and SPM, whose residual transport was towards the lagoon. The results pointed local hydrodynamics as an essential tool for understanding material transport and exchanges among the estuarine segments. A longer time series should be studied in order to obtain more robust conclusions

Seroprevalence of ehrlichia spp., anaplasma spp., borrelia burgdorferi sensu lato, and dirofilaria immitis in stray dogs, from 2016 to 2019, in southern Italy

Canine vector-borne diseases (CVBD) are an important and emerging health concern for humans and animals worldwide. The purpose of the presented study was to assess, from 2016 to 2019, the seroprevalence of CVBD agents and clarify the epidemiology of tick-borne disease in stray dogs living in the Campania Region, Southern Italy. For this purpose, blood samples were collected from January 2016 to December 2019 from 1023 dogs in authorized kennels located in the five municipalities of the Campania Region. SNAP® 4DX® from IDEXX® Laboratories was used for detection of Ehrlichia spp., Anaplasma spp., Borrelia burgdorferi sensu lato (s.l.), and Dirofilaria immitis antibodies. The overall seroprevalence of CVBD in stray dogs was 19.6% (95% Confidence Intervals (CI): 17.2–22.8%; 201/1023). The most common pathogen was Ehrlichia spp., with a percentage of positivity of 16.03%, followed by Anaplasma spp. with 7.8%. B. burgdorferi s.l. and D. immitis were detected in only 0.2% of dogs; co-infection was detected in 4.5% of stray dogs tested. No link was detected between the gender, age, location, and CVBD seropositivity, except for Ehrlichia spp. for which location (Avellino Province; p = 0.007) and gender (male, p = 0.002) were risk factors for seropositivity. Our results demonstrated that animals are exposed to at least one of the four etiological agents (Ehrlichia spp., Anaplasma spp. Borrelia burgdorferi s.l., and Dirofilaria immitis) transmitted by vectors. Finally, this study highlighted the utility of serological monitoring in stray dogs, housed in kennels, given the threat posed by CVBD to animals and the zoonotic implications of these etiological agents and their vectors on human health

A Pilot Study on Biochemical Profile of Follicular Fluid in Breast Cancer Patients

Breast cancer (BC) is the most common type of cancer among women in almost all countries worldwide and is one of the oncological pathologies for which is indicated fertility preservation, a type of procedure used to help keep a person's ability to have children. Follicular fluid (FF) is a major component of oocyte microenvironment, which is involved in oocyte growth, follicular maturation, and in communication between germ and somatic cells; furthermore, it accumulates all metabolites during oocytes growth. To obtain information about changes on fertility due to cancer, we aimed at investigating potential biomarkers to discriminate between FF samples obtained from 16 BC patients and 10 healthy women undergoing in vitro fertilization treatments. An NMR-based metabolomics approach was performed to investigate the FF metabolic profiles; ELISA and western blotting assays were used to investigate protein markers of oxidative and inflammatory stress, which are processes closely related to cancer. Our results seem to suggest that FFs of BC women display some significant metabolic alterations in comparison to healthy controls, and these variations are also related with tumor staging

Reduced Deadtime and Higher Rate Photon-Counting Detection using a Multiplexed Detector Array

We present a scheme for a photon-counting detection system that can be operated at incident photon rates higher than otherwise possible by suppressing the effects of detector deadtime. The method uses an array of N detectors and a 1-by-N optical switch with a control circuit to direct input light to live detectors. Our calculations and models highlight the advantages of the technique. In particular, using this scheme, a group of N detectors provides an improvement in operation rate that can exceed the improvement that would be obtained by a single detector with deadtime reduced by 1/N, even if it were feasible to produce a single detector with such a large improvement in deadtime. We model the system for continuous and pulsed light sources, both of which are important for quantum metrology and quantum key distribution applications.Comment: 6 figure