282 research outputs found

    Ballistic electron transport through magnetic domain walls

    Full text link
    Electron transport limited by the rotating exchange-potential of domain walls is calculated in the ballistic limit for the itinerant ferromagnets Fe, Co, and Ni. When realistic band structures are used, the domain wall magnetoresistance is enhanced by orders of magnitude compared to the results for previously studied two-band models. Increasing the pitch of a domain wall by confinement in a nano-structured point contact is predicted to give rise to a strongly enhanced magnetoresistance.Comment: 4 pages, 2 figures; to appear in PRB as a brief repor

    Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity.

    Get PDF
    Here we introduce Protein-indexed Assay of Transposase Accessible Chromatin with sequencing (Pi-ATAC) that combines single-cell chromatin and proteomic profiling. In conjunction with DNA transposition, the levels of multiple cell surface or intracellular protein epitopes are recorded by index flow cytometry and positions in arrayed microwells, and then subject to molecular barcoding for subsequent pooled analysis. Pi-ATAC simultaneously identifies the epigenomic and proteomic heterogeneity in individual cells. Pi-ATAC reveals a casual link between transcription factor abundance and DNA motif access, and deconvolute cell types and states in the tumor microenvironment in vivo. We identify a dominant role for hypoxia, marked by HIF1α protein, in the tumor microvenvironment for shaping the regulome in a subset of epithelial tumor cells

    Participation in and adherence to physical exercise after completion of primary cancer treatment

    Get PDF
    Contains fulltext : 171131.pdf (publisher's version ) (Open Access)BACKGROUND: The purpose of this study was to identify demographic, clinical, psychosocial, physical and environmental factors that are associated with participation in and adherence to a combined resistance and endurance exercise program among cancer survivors, shortly after completion of primary cancer treatment. Data from the randomized controlled Resistance and Endurance exercise After ChemoTherapy (REACT) study were used for this study. METHODS: The participants of the REACT study were randomly allocated to either a high intensity (HI) or low-to-moderate intensity (LMI) exercise program. Patients' participation rate was defined as the cancer survivors' decision to participate in the REACT study. Exercise adherence reflected participants' attendance to the scheduled exercise sessions and their compliance to the prescribed exercises. High session attendance rates were defined as attending at least 80 % of the sessions. High compliance rates were defined as performing at least of 90 % of the prescribed exercise across all sessions. Correlates of exercise adherence were studied separately for HI and LMI exercise. Demographic, clinical, and physical factors were assessed using self-reported questionnaires. Relevant clinical information was extracted from medical records. Multivariable logistic regression analyses were applied to identify correlates that were significantly associated with participation, high session attendance, high compliance with resistance and high compliance with endurance exercises. RESULTS: Participants were more likely to have higher education, be non-smokers, have lower psychological distress, higher outcome expectations, and perceive more exercise barriers than non-participants. In HI exercise, higher self-efficacy was significantly associated with high session attendance and high compliance with endurance exercises, and lower psychological distress was significantly associated with high compliance with resistance exercises. In LMI exercise, being a non-smoker was significantly associated with high compliance with resistance exercises and higher BMI was significantly associated with high compliance with resistance and endurance exercises. Furthermore, breast cancer survivors were less likely to report high compliance with resistance and endurance exercises in LMI exercise compared to survivors of other types of cancer. The discriminative ability of the multivariable models ranged from 0.62 to 0.75. CONCLUSION: Several demographic, clinical and psychosocial factors were associated with participation in and adherence to exercise among cancer survivors. Psychosocial factors were more strongly associated with adherence in HI than LMI exercise. TRIAL REGISTRATION: This study was registered at the Netherlands Trial Register [ NTR2153 ] on the 5(th) of January 2010

    Spin Torques in Ferromagnetic/Normal Metal Structures

    Get PDF
    Recent theories of spin-current-induced magnetization reversal are formulated in terms of a spin-mixing conductance GmixG^{mix}. We evaluate GmixG^{mix} from first-principles for a number of (dis)ordered interfaces between magnetic and non-magnetic materials. In multi-terminal devices, the magnetization direction of a one side of a tunnel junction or a ferromagnetic insulator can ideally be switched with negligible charge current dissipation.Comment: 4 pages, 1 figur

    Scattering theory of interface resistance in magnetic multilayers

    Full text link
    The scattering theory of transport has to be applied with care in a diffuse environment. Here we discuss how the scattering matrices of heterointerfaces can be used to compute interface resistances of dirty magnetic multilayers. First principles calculations of these interface resistances agree well with experiments in the CPP (current perpendicular to the interface plane) configuration.Comment: submitted to J. Phys. D (special issue at the occasion of Prof. T. Shinjo's 60th birthday

    Maharam-type kernel representation for operators with a trigonometric domination

    Full text link
    [EN] Consider a linear and continuous operator T between Banach function spaces. We prove that under certain requirements an integral inequality for T is equivalent to a factorization of T through a specific kernel operator: in other words, the operator T has what we call a Maharam-type kernel representation. In the case that the inequality provides a domination involving trigonometric functions, a special factorization through the Fourier operator is given. We apply this result to study the problem that motivates the paper: the approximation of functions in L2[0, 1] by means of trigonometric series whose Fourier coefficients are given by weighted trigonometric integrals.This research has been supported by MTM2016-77054-C2-1-P (Ministerio de Economia, Industria y Competitividad, Spain).Sánchez Pérez, EA. (2017). Maharam-type kernel representation for operators with a trigonometric domination. Aequationes Mathematicae. 91(6):1073-1091. https://doi.org/10.1007/s00010-017-0507-6S10731091916Calabuig, J.M., Delgado, O., Sánchez Pérez, E.A.: Generalized perfect spaces. Indag. Math. 19(3), 359–378 (2008)Calabuig, J.M., Delgado, O., Sánchez Pérez, E.A.: Factorizing operators on Banach function spaces through spaces of multiplication operators. J. Math. Anal. Appl. 364, 88–103 (2010)Delgado, O., Sánchez Pérez, E.A.: Strong factorizations between couples of operators on Banach function spaces. J. Convex Anal. 20(3), 599–616 (2013)Dodds, P.G., Huijsmans, C.B., de Pagter, B.: Characterizations of conditional expectation type operators. Pacific J. Math. 141(1), 55–77 (1990)Flores, J., Hernández, F.L., Tradacete, P.: Domination problems for strictly singular operators and other related classes. Positivity 15(4), 595–616 (2011). 2011Fremlin, D.H.: Tensor products of Banach lattices. Math. Ann. 211, 87–106 (1974)Hu, G.: Weighted norm inequalities for bilinear Fourier multiplier operators. Math. Ineq. Appl. 18(4), 1409–1425 (2015)Halmos, P., Sunder, V.: Bounded Integral Operators on L2 L^2 L 2 Spaces. Springer, Berlin (1978)Kantorovitch, L., Vulich, B.: Sur la représentation des opérations linéaires. Compositio Math. 5, 119–165 (1938)Kolwicz, P., Leśnik, K., Maligranda, L.: Pointwise multipliers of Calderón- Lozanovskii spaces. Math. Nachr. 286, 876–907 (2013)Kolwicz, P., Leśnik, K., Maligranda, L.: Pointwise products of some Banach function spaces and factorization. J. Funct. Anal. 266(2), 616–659 (2014)Kuo, W.-C., Labuschagne, C.C.A., Watson, B.A.: Conditional expectations on Riesz spaces. J. Math. Anal. Appl. 303, 509–521 (2005)Lindenstrauss, J., Tzafriri, L.: Classical Banach Spaces II. Springer, Berlin (1979)Maharam, D.: The representation of abstract integrals. Trans. Am. Math. Soc. 75, 154–184 (1953)Maharam, D.: On kernel representation of linear operators. Trans. Am. Math. Soc. 79, 229–255 (1955)Maligranda, L., Persson, L.E.: Generalized duality of some Banach function spaces. Indag. Math. 51, 323–338 (1989)Neugebauer, C.J.: Weighted norm inequalities for averaging operators of monotone functions. Publ. Mat. 35, 429–447 (1991)Okada, S., Ricker, W.J., Sánchez Pérez, E.A.: Optimal Domain and Integral Extension of Operators Acting in Function Spaces. Operator Theory: Adv. Appl., vol. 180. Birkhäuser, Basel (2008)Rota, G.C.: On the representation of averaging operators. Rend. Sem. Mat. Univ. Padova. 30, 52–64 (1960)Sánchez Pérez, E.A.: Factorization theorems for multiplication operators on Banach function spaces. Integr. Equ. Oper. Theory 80(1), 117–135 (2014)Schep, A.R.: Factorization of positive multilinear maps. Ill. J. Math. 28(4), 579–591 (1984)Schep, A.R.: Products and factors of Banach function spaces. Positivity 14(2), 301–319 (2010

    On the smoothness of L p of a positive vector measure

    Full text link
    The final publication is available at Springer via http://dx.doi.org/10.1007/s00605-014-0666-7We investigate natural sufficient conditions for a space L p(m) of pintegrable functions with respect to a positive vector measure to be smooth. Under some assumptions on the representation of the dual space of such a space, we prove that this is the case for instance if the Banach space where the vector measure takes its values is smooth. We give also some examples and show some applications of our results for determining norm attaining elements for operators between two spaces L p(m1) and Lq (m2) of positive vector measures m1 and m2.Professor Agud and professor Sanchez-Perez authors gratefully acknowledge the support of the Ministerio de Economia y Competitividad (Spain), under project #MTM2012-36740-c02-02. Professor Calabuig gratefully acknowledges the support of the Ministerio de Economia y Competitividad (Spain), under project #MTM2011-23164.Agud Albesa, L.; Calabuig Rodriguez, JM.; Sánchez Pérez, EA. (2015). On the smoothness of L p of a positive vector measure. Monatshefte für Mathematik. 178(3):329-343. https://doi.org/10.1007/s00605-014-0666-7S3293431783Beauzamy, B.: Introduction to Banach Spaces and Their Geometry. North-Holland, Amsterdam (1982)Diestel, J., Uhl, J.J.: Vector measures. In: Mathematical Surveys, vol. 15. AMS, Providence (1977)Fernández, A., Mayoral, F., Naranjo, F., Sáez, C., Sánchez-Pérez, E.A.: Spaces of p-integrable functions with respect to a vector measure. Positivity 10, 1–16 (2006)Ferrando, I., Rodríguez, J.: The weak topology on LpL^p L p of a vector measure. Topol. Appl. 155(13), 1439–1444 (2008)Godefroy, G.: Boundaries of a convex set and interpolation sets. Math. Ann. 277(2), 173–184 (1987)Howard, R., Schep, A.R.: Norms of positive operators on LpL^p L p -spaces. Proc. Am. Math. Soc. 109(1), 135–146 (1990)Lindenstrauss, J., Tzafriri, L.: Classical Banach Spaces II. Springer, Berlin (1977)Meyer-Nieberg, P.: Banach Latticces. Universitext, Springer-Verlag, Berlin (1991)Okada, S., Ricker, W.J., Sánchez-Pérez, E.A.: Optimal Domain and Integral Extension of Operators Acting in Function Spaces. Operator Theory: Advances and Applications, vol. 180. Birkhäuser Verlag, Basel (2008)Schep, A.: Products and factors of Banach function spaces. Positivity 14(2), 301–319 (2010

    Diagnosis and Management of Iliac Artery Endofibrosis: Results of a Delphi Consensus Study

    Get PDF
    Objective Iliac endofibrosis is a rare condition that may result in a reduction of blood flow to the lower extremity in young, otherwise healthy individuals. The data to inform everyday clinical management are weak and therefore a Delphi consensus methodology was used to explore areas of consensus and disagreement concerning the diagnosis and management of patients with suspected iliac endofibrosis. Methods A three-round Delphi questionnaire approach was used among vascular surgeons, sports physicians, sports scientists, radiologists, and clinical vascular scientists with experience of treating this condition to explore diagnosis and clinical management issues for patients with suspected iliac artery endofibrosis. Analysis is based on 18 responses to round 2 and 14 responses to round 3, with agreement reported when 70% of respondents were in agreement. Results Initially there was agreement on the typical symptoms at presentation and the need for an exercise test in the diagnosis. Round 3 clarified that duplex ultrasound was a useful tool in the diagnosis of endofibrosis. There was consensus on the most appropriate type of surgery (endarterectomy and vein patch) and that endovascular interventions were inadvisable. The final round helped to inform aspects of the natural history and post-operative surveillance. Progression of the disease was likely with continued exercise but cessation may prevent progression. Surveillance after surgery is generally recommended yearly with at least a clinical assessment. Conclusions There is broad agreement about the presenting symptoms and the investigations required to confirm (or exclude) the diagnosis of iliac endofibrosis. There was consensus on the surgical approach to repair. Disagreement existed about the specific diagnostic criteria that should be applied during non-invasive testing and about post-operative care and resumption of exercise

    Observation of a controllable PI-junction in a 3-terminal Josephson device

    Full text link
    Recently Baselmans et al. [Nature, 397, 43 (1999)] showed that the direction of the supercurrent in a superconductor/normal/superconductor Josephson junction can be reversed by applying, perpendicularly to the supercurrent, a sufficiently large control current between two normal reservoirs. The novel behavior of their 4-terminal device (called a controllable PI-junction) arises from the nonequilibrium electron energy distribution established in the normal wire between the two superconductors. We have observed a similar supercurrent reversal in a 3-terminal device, where the control current passes from a single normal reservoir into the two superconductors. We show theoretically that this behavior, although intuitively less obvious, arises from the same nonequilibrium physics present in the 4-terminal device. Moreover, we argue that the amplitude of the PI-state critical current should be at least as large in the 3-terminal device as in a comparable 4-terminal device.Comment: 4 pages, 4 figures, to appear in Physical Review B Rapid Communication

    Spin battery operated by ferromagnetic resonance

    Full text link
    Precessing ferromagnets are predicted to inject a spin current into adjacent conductors via Ohmic contacts, irrespective of a conductance mismatch with, for example, doped semiconductors. This opens the way to create a pure spin source spin battery by the ferromagnetic resonance. We estimate the spin current and spin bias for different material combinations.Comment: The estimate for the magnitude of the spin bias is improved. We find that it is feasible to get a measurable signal of the order of the microwave frequency already for moderate rf intensitie
    corecore