"If You Can't Beat them, Join them": A Usability Approach to Interdependent Privacy in Cloud Apps

Cloud storage services, like Dropbox and Google Drive, have growing ecosystems of 3rd party apps that are designed to work with users' cloud files. Such apps often request full access to users' files, including files shared with collaborators. Hence, whenever a user grants access to a new vendor, she is inflicting a privacy loss on herself and on her collaborators too. Based on analyzing a real dataset of 183 Google Drive users and 131 third party apps, we discover that collaborators inflict a privacy loss which is at least 39% higher than what users themselves cause. We take a step toward minimizing this loss by introducing the concept of History-based decisions. Simply put, users are informed at decision time about the vendors which have been previously granted access to their data. Thus, they can reduce their privacy loss by not installing apps from new vendors whenever possible. Next, we realize this concept by introducing a new privacy indicator, which can be integrated within the cloud apps' authorization interface. Via a web experiment with 141 participants recruited from CrowdFlower, we show that our privacy indicator can significantly increase the user's likelihood of choosing the app that minimizes her privacy loss. Finally, we explore the network effect of History-based decisions via a simulation on top of large collaboration networks. We demonstrate that adopting such a decision-making process is capable of reducing the growth of users' privacy loss by 70% in a Google Drive-based network and by 40% in an author collaboration network. This is despite the fact that we neither assume that users cooperate nor that they exhibit altruistic behavior. To our knowledge, our work is the first to provide quantifiable evidence of the privacy risk that collaborators pose in cloud apps. We are also the first to mitigate this problem via a usable privacy approach.Comment: Authors' extended version of the paper published at CODASPY 201

Strong electron correlations in the normal state of FeSe0.42Te0.58

We investigate the normal state of the '11' iron-based superconductor FeSe0.42Te0.58 by angle resolved photoemission. Our data reveal a highly renormalized quasiparticle dispersion characteristic of a strongly correlated metal. We find sheet dependent effective carrier masses between ~ 3 - 16 m_e corresponding to a mass enhancement over band structure values of m*/m_band ~ 6 - 20. This is nearly an order of magnitude higher than the renormalization reported previously for iron-arsenide superconductors of the '1111' and '122' families but fully consistent with the bulk specific heat.Comment: 5 pages, 4 figures, to appear in Phys. Rev. Let

Swarm Keeping Strategies for Spacecraft under J_2 and Atmospheric Drag Perturbations

This paper presents several new open-loop guidance methods for spacecraft swarms composed of hundreds to thousands of agents with each spacecraft having modest capabilities. These methods have three main goals: preventing relative drift of the swarm, preventing collisions within the swarm, and minimizing the propellant used throughout the mission. The development of these methods progresses by eliminating drift using the Hill-Clohessy-Wiltshire equations, removing drift due to nonlinearity, and minimizing the J_2 drift. In order to verify these guidance methods, a new dynamic model for the relative motion of spacecraft is developed. These dynamics include the two main disturbances for spacecraft in Low Earth Orbit (LEO), J_2 and atmospheric drag. Using this dynamic model, numerical simulations are provided at each step to show the effectiveness of each method and to see where improvements can be made. The main result is a set of initial conditions for each spacecraft in the swarm which provides the trajectories for hundreds of collision-free orbits in the presence of J_2. Finally, a multi-burn strategy is developed in order to provide hundreds of collision-free orbits under the influence of atmospheric drag. This last method works by enforcing the initial conditions multiple times throughout the mission thereby providing collision-free trajectories for the duration of the mission

Graph partitions and cluster synchronization in networks of oscillators

Synchronization over networks depends strongly on the structure of the coupling between the oscillators. When the coupling presents certain regularities, the dynamics can be coarse-grained into clusters by means of External Equitable Partitions of the network graph and their associated quotient graphs. We exploit this graph-theoretical concept to study the phenomenon of cluster synchronization, in which different groups of nodes converge to distinct behaviors. We derive conditions and properties of networks in which such clustered behavior emerges and show that the ensuing dynamics is the result of the localization of the eigenvectors of the associated graph Laplacians linked to the existence of invariant subspaces. The framework is applied to both linear and non-linear models, first for the standard case of networks with positive edges, before being generalized to the case of signed networks with both positive and negative interactions. We illustrate our results with examples of both signed and unsigned graphs for consensus dynamics and for partial synchronization of oscillator networks under the master stability function as well as Kuramoto oscillators

T Regulatory Cells in Cord Blood—FOXP3 Demethylation as Reliable Quantitative Marker

Regulatory T-cells (Tregs), characterized as CD4+CD25(hi) T-cells expressing FOXP3, play a crucial role in controlling healthy immune development during early immune maturation. Recently, FOXP3 demethylation was suggested to be a novel marker for natural Tregs in adults. In cord blood, the role and function of Tregs and its demethylation is poorly understood. We assessed FOXP3 demethylation in cord blood in relation to previously used Treg markers such as CD4+CD25(hi), FOXP3 mRNA, protein expression, and suppressive Treg function

Effectiveness of a web-based self-help tool to reduce problem gambling: A randomized controlled trial.

Problem gambling constitutes a public health concern associated with psychopathological comorbidity, substance use, and financial difficulties. Most individuals with gambling problems avoid counseling services due to perceived stigma and their preference for self-reliance. Treatment accessibility could be improved through web-based interventions. We recruited 360 individuals with gambling problems and randomized them to a web-based intervention (n = 185) or an active control group consisting of a self-help manual for problem gambling (n = 175). The primary outcome was the number of days of gambling in the last 30 days. Secondary outcomes included money spent in the last 30 days, time gambling in the last 7 days, gambling-related problems, consumption of alcohol and cigarettes, and psychopathological comorbidity measured at posttreatment and 6-month follow-up. The primary outcome decreased significantly for both groups, with no significant difference between the groups. There were significant group × time interactions according to the Gambling Symptom Assessment Scale (F = 8.83, p <0 .001), the Problem Gambling Severity Index (F = 3.54, p = 0.030), for cigarettes smoked in the last 7 days (F = 26.68, p < 0.001), the Patient Health Questionnaire-9 (F = 19.41, p <0 .001), and the Generalized Anxiety Disorder-7 (F = 41.09, p <0 .001) favoring the intervention group. We experienced an overall high dropout rate (76%). Win Back Control seems to be an effective low-threshold treatment option for individuals with gambling problems that might otherwise be unapproachable for outpatient treatment services. Nevertheless, the high dropout rate should be considered when interpreting the study results, as they may have introduced a degree of variability

Dynamics of heteropolymers in dilute solution: effective equation of motion and relaxation spectrum

The dynamics of a heteropolymer chain in solution is studied in the limit of long chain length. Using functional integral representation we derive an effective equation of motion, in which the heterogeneity of the chain manifests itself as a time-dependent excluded volume effect. At the mean field level, the heteropolymer chain is therefore dynamically equivalent to a homopolymer chain with both time-independent and time-dependent excluded volume effects. The perturbed relaxation spectrum is also calculated. We find that heterogeneity also renormalizes the relaxation spectrum. However, we find, to the lowest order in heterogeneity, that the relaxation spectrum does not exhibit any dynamic freezing, at the point when static (equilibrium) ``freezing'' transition occurs in heteropolymer. Namely, the breaking of fluctuation-dissipation theorem (FDT) proposed for spin glass dynamics does not have dynamic effect in heteropolymer, as far as relaxation spectrum is concerned. The implication of this result is discussed

Experimental Comparison and Evaluation of the Affymetrix Exon and U133Plus2 GeneChip Arrays

Affymetrix exon arrays offer scientists the only solution for exon-level expression profiling at the whole-genome scale on a single array. These arrays feature a new chip design with no mismatch probes and a radically new random primed protocol to generate sense DNA targets along the entire length of the transcript. In addition to these changes, a limited number of validating experiments and virtually no experimental data to rigorously address the comparability of all-exon arrays with conventional 3'-arrays result in a natural reluctance to replace conventional expression arrays with the new all-exon platform.Using commercially available Affymetrix arrays, we assess the performance of the Human Exon 1.0 ST (HuEx) and U133 Plus 2.0 (U133Plus2) platforms directly through a series of 'spike-in' hybridizations containing 25 transcripts in the presence of a fixed eukaryotic background. Specifically, we compare the measures of expression for HuEx and U133Plus2 arrays to evaluate the precision of these measures as well as the specificity and sensitivity of the measures' ability to detect differential expression.This study presents an experimental comparison and systematic cross-validation of Affymetrix exon arrays and establishes high comparability of expression changes and probe performance characteristics between Affymetrix conventional and exon arrays. In addition, this study offers a reliable benchmark data set for the comparison of competing exon expression measures, the selection of methods suitable for mapping exon array measures to the wealth of previously generated microarray data, as well as the development of more advanced methods for exon- and transcript-level expression summarization

Climate change and the global pattern of moraine-dammed glacial lake outburst floods

This is the author accepted manuscript. The final version is available from EGU via the DOI in this recordThe published version, as published in The Cryosphere, is in ORE: http://hdl.handle.net/10871/32433Despite recent research identifying a clear anthropogenic impact on glacier recession, the effect of recent climate change on glacier-related hazards is at present unclear. Here we present the first global spatio-temporal assessment of glacial lake outburst floods (GLOFs) focusing explicitly on lake drainage following moraine dam failure. These floods occur as mountain glaciers recede and downwaste and many have an enormous impact on downstream communities and infrastructure. Our assessment of GLOFs associated with the collapse of moraine-dammed lakes provides insights into the historical trends of GLOFs and their distributions under current and future global climate change. We observe a clear global increase in GLOF frequency and their regularity around 1930, which likely represents a lagged response to post-Little Ice Age warming. Notably, we also show that GLOF frequency and their regularity – rather unexpectedly – has declined in recent decades even during a time of rapid glacier recession. Although previous studies have suggested that GLOFs will increase in response to climate warming and glacier recession, our global results demonstrate that this has not yet clearly happened. From assessment of the timing of climate forcing, lag times in glacier recession, lake formation and moraine dam failure, we predict increased GLOF frequencies during the next decades and into the 22nd century.SH was funded by a Leverhulme Research Fellowship. SH, RAB and AW acknowledge funding under the HELIX (European Union Seventh Framework Programme FP7/2007-2013 under grant agreement n° 603864). AW and RAB acknowledge funding from the Joint UK DECC/Defra Met Office Hadley Centre Climate Programme (GA01101)