26 research outputs found

    Метаболическая активность митохондрий корней гороха в условиях моделированной микрогравитации

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    Наведено дані досліджень впливу кліностатування на метаболічну активність мітохондрій, ізольованих із коренів 5-добових проростків гороху (Pisum sativum L). Встановлено збільшення швидкості окиснення в стані 3 малату+глутамату та екзогенного НАДН, а також значення коефіцієнта дихального контролю одночасно зі зниженням відношення АДФ/О порівняно з контролем. Висловлено припущення, що такі зміни характеру дихання є наслідком адаптації метаболічної системи мітохондрій до умов кліностатування.The effect of clinorotation on the respiration of mitochondria isolated from roots of pea 5-day-old seedlings has been examined. An increase in the rate of oxidation of malate and NADH in state 3 is detected. A respiratory control ratio is also increased simultaneously with a decrease in the efficiency of oxidative phosphorylation. Such character of mitochondrial respiration under simulated microgravity is supposed to be a consequence of the adaptation to these conditions

    Sexuality in patients with asthma and COPD

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    SummarySexual quality of life was examined in 55 outpatients with chronic obstructive pulmonary disease (COPD) and asthma, using disease-specific questionnaires. Compared to an age- and sex-matched norm group, male patients with COPD reported a significantly lower sexual quality of life on all dimensions of the questionnaire. Female patients with COPD reported a lower frequency of sexual intimacy and lower sexual quality of life overall. Patients with asthma reported sexual quality-of-life scores that were somewhat better than COPD patients but worse than the healthy control group. Patients reported that they did not discuss sexual quality-of-life issues with their physician. Sexuality needs to be discussed by the health care provider in the consultation in order to improve quality of life of patients with chronic respiratory disorders

    Concerns About Exercise Are Related to Walk Test Results in Pulmonary Rehabilitation for Patients with COPD

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    # The Author(s). This article is published with open access at Springerlink.com 2010 Background Although international guidelines on pulmonary rehabilitation acknowledge that psychological factors contribute to exercise intolerance in patients with chronic obstructive pulmonary disease (COPD), the few empirical studies investigating this association have found inconsistent results. Purpose The purpose of this study is to investigate whether negative affect and beliefs about exercise of patients with COPD would be related to baseline 6-min walk (6-MW) test results in a pulmonary rehabilitation setting, after correction for physical variables (sex, age, height, weight, and lung function). A second aim was to examine whethe

    When the ringing in the earsgetsunbearable : Illness representations, self-instructions and adjustment to tinnitus

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    ObjectiveChronic tinnitus can severely impair a person's quality of life. The degree of impairment, however, is not closely related to tinnitus loudness. Applying the common sense model (CSM) of self-regulation of health and illness, this study investigated to what extent psychological factors, i.e. illness representations and positive/negative self-instructions, are associated with the degree of tinnitus-related complaints.MethodsIn this cross-sectional study, 118 patients diagnosed with chronic tinnitus filled in questionnaires assessing illness representations (IPQ-R), positive and negative self-instructions (TRSS), and tinnitus-related complaints (TQ).ResultsThe regression analysis yielded a number of significant associations between illness representations and tinnitus-related complaints, particularly for the IPQ-R dimensions identity, consequences, coherence, and emotional representations. With regard to self-instructions and tinnitus-related complaints, significant effects were found only for negative self-instructions. Moreover, multiple mediation analyses revealed that the effects of consequences and emotional representations on tinnitus-related complaints were (partially) due to the use of negative self-instructions.ConclusionPsychological factors are strongly related to the extent of tinnitus-related complaints. The findings provide an indication of which aspects should be targeted in psychological and psychotherapeutic tinnitus treatment

    Illness perceptions about asthma are determinants of outcome

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    This article reviews an emerging area of research on patients with asthma: namely, illness perceptions and their relationships with various aspects of outcome. The article briefly introduces the Common Sense Model, outlining the relevance of how "lay" patients conceptualize symptoms, illness, and treatment. On the basis of a comprehensive literature search, nine empirical studies illustrating the relationships between illness perceptions and outcomes are discussed. It is concluded that further research should focus on assessing asthma-specific illness and treatment beliefs. Also, given the effects of intervention studies in illness perceptions in other patient categories, it is recommended that serious consideration be given to intervention studies focusing on eliciting and changing illness perceptions in asthma patients, especially in those whose self-management seems to be inadequate

    Illness perceptions and quality of life in patients with chronic obstructive pulmonary disease

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    This study aimed at identifying cognitive and emotional representations relevant for improving health care communication and quality of life (QoL) in patients with chronic obstructive pulmonary disease (COPD). One-hundred-seventy-one COPD outpatients completed questionnaires on illness perceptions and QoL. After controlling for the effects of age, pulmonary function, and dyspnea, patients with decreased attention to symptoms, with more positive beliefs about the effects and outcomes of their illness, and with less strong emotional reactions to the illness, had higher QoL scores. The results of this study are discussed in relation to the associations found in other illnesse
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