Videokonferenzen Augsburg – Chabarovsk: Erfahrungen, Probleme und Perspektiven

Die zwölfjährige GIP zwischen den Germanistiklehrstühlen der Universität Augsburg und der Staatlichen Pädagogischen (heute: Humanwissenschaftlichen) Universität Chabarovsk unter der Leitung von Prof. Dr. Hans Wellmann und Frau Dr. Elena Kan brachte fachliche Aktivitäten unterschiedlichster Art hervor. Im wissenschaftlichen Bereich wurde diese Zusammenarbeit ab 1999 durch eine Reihe gemeinsamer Videokonferenzen unterstützt. Dabei waren die Eingangsvoraussetzungen an beiden Partneruniversitäten recht unterschiedlich

History of Nicolae Testemitsanu State University of Medicine and Pharmacy through its rectors

Nicolae Anestiadi Department of Surgery, Nicolae Testemitsanu Department of Social Medicine and Sanitary Management, Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, the Republic of MoldovaBackground: The authors present the history of Nicolae Testemitsanu State University of Medicine and Pharmacy from the beginning, since the transfer of Leningrad Institute of Medicine No 1 in November 1945. Rectors: Ipatie Sorocean, Nicolai Harauzov, Leonid Ganul, Nicolae Starostenco, Nicolae Testemitsanu, Vasile Anestiadi, Leonid Cobaleanschi, Ion Ababii are presented with a broad feature of their work – teaching, scientific, managerial. A particular attention is given to rectors academicians: Nicolae Testemitsanu, Vasile Anestiadi and current rector Ion Ababii. A decisive role in the development of the university belongs to Nicolae Testemitsanu, who was the first local rector to promote national staff, contributed to the opening of the faculties of Dentistry, Continuous Medical Education, Preventive Medicine and Pharmacy. He sent local staff for advanced studies to different USSR centers, who after returning occupied the positions of heads of departments and laboratories. Vasile Anestiadi continued the promotion of the university, which became one of the most prestigious medical institutions in the former Soviet Union. Ion Ababii, the current rector, has promoted the university applying European ideas, liaising with other universities of the same type, a strategic partnership with future effects. Thus, Nicolae Testemitsanu State University of Medicine and Pharmacy reached the anniversary of 70 years, having an imposing history and a foreseeable future, occupying a deserved place among higher educational institutions of the Republic of Moldova. Conclusions: The history of Nicolae Testemitsanu State University of Medicine and Pharmacy represents an important page of our country’s history. The teaching team brings new achievements in the training process of medical staff of the Republic of Moldova

Pulmonary thromboembolism associated with surgical diseases

Nicolae Anestiadi Department of Surgery, Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, the Republic of MoldovaBackground: The pulmonary thromboembolism (PTE) has demonstrated a serious evolution and a high lethality level and is on the third place as a cause of a sudden death and remains one of the most actual issues in medicine. The actuality of the problem consists not only in the disease severity and lethality, but also in the difficulties in the diagnostics. Material and methods: By the necropsy data, the incidence of PTE is estimated as about 15% of cases. A retrospective study of 33 patients who died from PTE in the period of 2008-2013 is presented. In the studied group the following risk factors have been identified: intravenous catheters, surgery, immobilization in bed, smoking and atrial fibrillation. In the studied group PTE prophylaxis has been performed with heparin, nadroparin and enoxaparin. The authors have been dissatisfied with the research due to PTE fatality. Results: It has been revealaed that an important factor in decreasing the lethality is the administration of antiplatelet drug support to all the patients with PTE risk. Conclusions: 1. PTE is a frequent complication with a high lethality even in the case of its prevention. 2. The presence of risk factors, regardless of their number, strongly requires a preventive treatment. 3. The most effective anticoagulant drugs at the moment are those from the group of anticoagulants with a low molecular weight in preventive doses (Fondaparinux, Enoxaparin, Nadroparin). 4. It is necessary to reevaluate the anticoagulant medication support and prescribe it to the people above 40 years old. 5. The problem of PTE remains open for the further research with regard to the evidences of risk factors and the lethality decrease

Синдром Буверета

According to the literature Bouveret’s syndrome is a rare disease with an unclear clinical picture and difficulties in diagnosis. The known diagnostic methods include X-ray examination, ultrasonography, computerized tomography, the endoscopic examination of the gastrointestinal tract. Researchers indicate that the most successful diagnosis can be made when combining ultrasound and contrast radiography. There isn’t a clear opinion about Bouveret’s syndrome surgical treatment. Preference is given to the simple methods - enterotomy with the extraction of the biliary concrement leaving the elimination of the fistula and cholecystectomy for the second phase of treatment. In this case there appear a risk of the recurrence of biliary obstruction and the occurrence of cholangitis. A clinic case of a 62-year-old woman, who had difficulties in the diagnosis of biliary ileus has been described. The clinical picture has not corresponded to the X-ray examination results. The increase of obstruction syndrome and lack of the effect of conservative therapy have required a classical surgical treatment. In this case the solution of the problem has been reached by one stage treatment: cholecystectomy, enterotomy with gall stone extraction and the liquidation of gastric defect. The postoperative period has been complicated with a bilateral pleurisy, which has been succesfully cured by carrying out the pleural puncture and antibiotic therapy.В соответствии с данными литературы, синдром Буверета – это редкое заболевание с неясной клинической картиной и сложной диагностикой. Среди методов его диагностики наиболее известны рентгенологические методы, ультразвуковое исследование, компьютерная томография, эндоскопическое исследование желудочно-кишечного тракта. Исследователи отмечают наибольшую вероятность успешной диагностики при сочетании УЗИ с контрастным рентгенологическим исследованием. Нет единого мнения и относительно хирургического лечения синдрома Буверета. Предпочтение отдаётся простым методам – энтеротомии с удалением желчного камня, при том, что ликвидация свища и холецистэктомия остаются на второй этап лечения. Но, в этом случае остаётся опасность рецидива билиарной непроходимости и возникновения холангита. Приводится клинический случай женщины 62 лет, у которой были трудности диагностики кишечной непроходимости билиарного генеза. Клиническая картина не соответствовала данным рентгенологического исследования. Нарастание клиники кишечной непроходимости и отсутствие эффекта от консервативной терапии потребовало хирургического лечения классическим способом. В нашем случае решение проблемы достигнуто проведением одноэтапного лечения: холецистэктомия, энтеротомия с извлечением камня и закрытие дефекта желудка. Послеоперационный период осложнился двухсторонним плевритом, который успешно вылечили посредством проведения плевральной пункции и терапии антибиотиками

Analysis of oscillations of single-mass systems with two degrees of freedom

The focus of this bachelor's thesis is the division, modelling, simulation, and subsequent analysis of single-mass systems with two degrees of freedom, which can replace various mechanical systems under certain assumptions. Part of the system division involves deriving general cases that involve situations where the interdependence between mutually perpendicular coupling elements is considered. The Simulink environment, based on the MATLAB platform, was used for computational simulation. The simulation results were processed using MATLAB. To enhance user experience, applications were developed in the MATLAB GUI environment for each case of the examined systems. The results of the analysis indicate that the mutual interaction of coupling elements has a significant impact on the simulation, with the position of the main system resonances being most affected. The developed method for solving systems of differential equations using Simulink and MATLAB could be applied to systems with a larger number of differential equations

Differences in Reading Strategies and Differential Item Functioning on PCAP 2007 Reading Assessment

Pan-Canadian Assessment Program (PCAP) 2007 reading ability item data and contextual data on reading strategies were analyzed to investigate the relationship between self-reported reading strategies and item difficulty. Students who reported using higher- or lower-order strategies were identified through a factor analysis. The purpose of this study was to investigate whether students with the same underlying reading ability but who reported using different reading strategies found the items differentially difficult. Differential item functioning (DIF) analyses identified the items on which students who tended to use higher-order reading strategies excelled, which were selected response items, but students who preferred using lower-order strategies found these items more difficult. The opposite pattern was found for constructed response items. The results of the study suggest that DIF analyses can be used to investigate which reading strategies are related to item difficulty when controlling for students’ level of ability.MAS

Acute Administration of Ethanol and of a D1-Receptor Antagonist Affects the Behavior and Neurochemistry of Adult Zebrafish

Alcohol abuse represents major societal problems, an unmet medical need resulting from our incomplete understanding of the mechanisms underlying alcohol’s actions in the brain. To uncover these mechanisms, animal models have been proposed. Here, we explore the effects of acute alcohol administration in zebrafish, a promising animal model in alcohol research. One mechanism via which alcohol may influence behavior is the dopaminergic neurotransmitter system. As a proof-of-concept analysis, we study how D1 dopamine-receptor antagonism may alter the effects of acute alcohol on the behavior of adult zebrafish and on whole brain levels of neurochemicals. We conduct these analyses using a quasi-inbred strain, AB, and a genetically heterogeneous population SFWT. Our results uncover significant alcohol x D1-R antagonist interaction and main effects of these factors in shoaling, but only additive effects of these factors in measures of exploratory behavior. We also find interacting and main effects of alcohol and the D1-R antagonist on dopamine and DOPAC levels, but only alcohol effects on serotonin. We also uncover several strain dependent effects. These results demonstrate that acute alcohol may act through dopaminergic mechanisms for some but not all behavioral phenotypes, a novel discovery, and also suggest that strain differences may, in the future, help us identify molecular mechanisms underlying acute alcohol effects