21 research outputs found
Effects of ionizing radiation on the activity of the major hepatic enzymes implicated in bile acid biosynthesis in the rat
Occupational cataracts and lens opacities in interventional cardiology (O'CLOC study): are X-Rays involved? Radiation-induced cataracts and lens opacities.
International audienceBACKGROUND: The eye is well known to be sensitive to clearly high doses (>2 Gy) of ionizing radiation. In recent years, however, cataracts have been observed in populations exposed to lower doses. Interventional cardiologists are repeatedly and acutely exposed to scattered ionizing radiation (X-rays) during the diagnostic and therapeutic procedures they perform. These "low" exposures may cause damage to the lens of the eye and induce early cataracts, known as radiation-induced cataracts. The O'CLOC study (Occupational Cataracts and Lens Opacities in interventional Cardiology) was designed to test the hypothesis that interventional cardiologists, compared with an unexposed reference group of non-interventional cardiologists, have an increased risk of cataracts. METHOD/DESIGN: The O'CLOC study is a cross-sectional study that will include a total of 300 cardiologists aged at least 40 years: one group of exposed interventional cardiologists and another of non-interventional cardiologists. The groups will be matched for age and sex. Individual information, including risk factors for cataracts (age, diabetes, myopia, etc.), will be collected during a telephone interview. A specific section of the questionnaire for the exposed group focuses on occupational history, including a description of the procedures (type, frequency, radiation protection tool) used. These data will be used to classify subjects into "exposure level" groups according to cumulative dose estimates. Eye examinations for all participants will be performed to detect cataracts, even in the early stages (lens opacities, according to LOCS III, the international standard classification). The analysis will provide an estimation of the cataract risk in interventional cardiology compared with the unexposed reference group, while taking other risk factors into account. An analysis comparing the risks according to level of exposure is also planned. DISCUSSION: This epidemiological study will provide further evidence about the potential risk of radiation-induced cataracts at low doses and contribute to cardiologists' awareness of the importance of radiation protection. TRIAL REGISTRATION: NCT01061463
Effets de traitements technologiques du lait sur la digestion gastrique des lactoproteines chez le veau preruminant
SIGLEAvailable from INIST (FR), Document Supply Service, under shelf-number : T 78699 / INIST-CNRS - Institut de l'Information Scientifique et TechniqueFRFranc
Alteration of both intestinal reabsorption and hepatic secretion modifies bile acid profiles in rat gut after exposure to ionizing radiation
Rôle du yoga adapté dans le traitement thérapeutique de l’anorexie mentale
International audienceL’anorexie mentale est un trouble du comportement alimentaire complexe ayant des répercussions néfastes sur la santé physique (i.e. le corps) et mentale des patientes (i.e. l’esprit) (Bulik, Reba, Siega-Riz, & Reichborn-Kjennerud, 2005). Le diagnostic de l’anorexie mentale repose sur trois critères cliniques précis, issus des classifications internationales(DSM V – Diagnostic and Statistics Manual of Mental Disorders ; American Psychiatric Association, 2013) : (1) des restrictions énergétiques menant à un poids inférieur au poids normal pour le sexe, l’âge et la taille ; (2) une peur intense de prendre du poids ou de devenir gros et (3) une altération de la perception du poids et du corps avec influence sur l’estime de soi et un déni de la gravité de la maigreur actuelle. Même s’il est récusable de restreindre l’anorexie mentale aux troubles de l’image du corps, force est de constater, au travers de ces critères diagnostiques, que la notion du corps est amplement investie dans la psychopathologie des patientes anorexiques.L’objectif de cet article est d’identifier l’impact des pratiques physiques de bien-être, dont le yoga, dans le traitement thérapeutique de l’anorexie mentale. Pour ce faire, nous définirons dans un premier temps l’image du corps. Nous verrons ensuite comment se caractérisent les troubles de l’image du corps dans l’anorexie mentale. Enfin, nous ferons un état des lieux de l’inclusion de l’activité physique, et en particulier des pratiques physiques de bien-être dans la prise en charge thérapeutique de l’anorexie mentale
L’anorexie et l’activité physique, une relation ambiguë
Bien qu’il soit communément admis que l’activité physique régulière contribue au
bien-être physique et mental de l’individu, pratiquée en excès, elle peut favoriser la
mise en place de conduites à risque. En effet, une pratique excessive associée à une
restriction alimentaire peut engendrer, dans les cas les plus graves, une anorexie
mentale. Le domaine sportif est également concerné par une forme subclinique d’anorexie
appelée l’anorexie athlétique, où la minceur est fortement reliée à la performance et Ã
l’apparence. Néanmoins, des observations de terrain ont montré que l’activité physique,
lorsqu’elle est pratiquée de façon adaptée, peut contribuer positivement au traitement
thérapeutique de l’anorexie mentale. La place de la pratique physique dans les troubles du
comportement alimentaire sera ainsi questionnée dans cette revue de littérature
A model-driven approach to studying dissociations between body size mental representations in anorexia nervosa
International audienceThis study compared dissociations between mental representations of current, ideal and normal body sizes (i.e., Current BS, Ideal BS and Normal BS) for women with anorexia nervosa (AN group, n=56) and healthy women (control group, n=56). Along the lines of the single channel model of Cornelissen et al. (2013), the discrepancy between Current BS and BMI for both groups was adequately described along a common linear continuum of Current BS (mis)perception. Body size mental representations were ranked similarly (Ideal BS<Current BS<Normal BS) in each group. Whilst the over-estimation of Current BS was much greater among the AN group than the control group, body dissatisfaction was better explained by Current BS for the AN group and by BMI for the control group. Dissociation between Current BS and participants' BMI appears to be a key element when seeking to understand AN
In vitro simulation of gastric digestion of milk proteins: comparison between in vitro and in vivo data
Modification of intestinal bile acid-binding protein (I-BABP) expression after exposure to ionising radiation
International audienc