10,885 research outputs found
Kinematic stability of roller pairs in free rolling contact
A set of generalized stability equations was developed for roller pairs in free rolling contact. A symmetric, dual contact model was used. Four possible external contact profiles that possess continuous contacting surfaces were studied. It was found that kinematic stability would be insured if the larger radius of transverse curvature, in absolute value, and the smaller rolling radius both exist on the roller that has the apex of its conical surface outboard of its main body. The stability criteria developed are considered to be useful for assessing axial restraint requirements for a variety of roller mechanisms and in the selection of roller contact geometry for traction drive devices
Argon protects against hypoxic-ischemic brain injury in neonatal rats through activation of Nuclear factor (erythroid-derived 2)-like 2
Perinatal hypoxic ischaemic encephalopathy (HIE) has a high mortality rate with neuropsychological impairment. This study investigated the neuroprotective effects of argon against neonatal hypoxic-ischaemic brain injury. In vitro cortical neuronal cell cultures derived from rat foetuses were subjected to an oxygen and glucose deprivation (OGD) challenge for 90 minutes and then exposed to 70% argon or nitrogen with 5% carbon dioxide and balanced with oxygen for 2 hours. In vivo, seven-day-old rats were subjected to unilateral common carotid artery ligation followed by hypoxic (8% oxygen balanced with nitrogen) insult for 90 minutes. They were exposed to 70% argon or nitrogen balanced with oxygen for 2 hours. In vitro, argon treatment of cortical neuronal cultures resulted in a significant increase of p-mTOR and Nuclear factor (erythroid-derived 2)-like 2(Nrf2) and protection against OGD challenge. Inhibition of m-TOR through Rapamycin or Nrf2 through siRNA abolished argon-mediated cyto-protection. In vivo, argon exposure significantly enhanced Nrf2 and its down-stream effector NAD(P)H Dehydrogenase, Quinone 1(NQO1) and superoxide dismutase 1(SOD1). Oxidative stress, neuroinflammation and neuronal cell death were significantly decreased and brain infarction was markedly reduced. Blocking PI-3K through wortmannin or ERK1/2 through U0126 attenuated argon-mediated neuroprotection. These data provide a new molecular mechanism for the potential application of Argon as a neuroprotectant in HIE
Heap Formation in Granular Media
Using molecular dynamics (MD) simulations, we find the formation of heaps in
a system of granular particles contained in a box with oscillating bottom and
fixed sidewalls. The simulation includes the effect of static friction, which
is found to be crucial in maintaining a stable heap. We also find another
mechanism for heap formation in systems under constant vertical shear. In both
systems, heaps are formed due to a net downward shear by the sidewalls. We
discuss the origin of net downward shear for the vibration induced heap.Comment: 11 pages, 4 figures available upon request, Plain TeX, HLRZ-101/9
Angle of Repose and Angle of Marginal Stability: Molecular Dyanmics of Granular Particles
We present an implementation of realistic static friction in molecular
dynamics (MD) simulations of granular particles. In our model, to break
contacts between two particles, one has to apply a finite amount of force,
determined by the Coulomb criterion. Using a two dimensional model, we show
that piles generated by avalanches have a {\it finite} angle of repose
(finite slopes). Furthermore, these piles are stable under tilting
by an angle smaller than a non-zero tilting angle , showing that
is different from the angle of marginal stability ,
which is the maximum angle of stable piles. These measured angles are compared
to a theoretical approximation. We also measure by continuously
adding particles on the top of a stable pile.Comment: 14 pages, Plain Te
On Characterizing the Data Access Complexity of Programs
Technology trends will cause data movement to account for the majority of
energy expenditure and execution time on emerging computers. Therefore,
computational complexity will no longer be a sufficient metric for comparing
algorithms, and a fundamental characterization of data access complexity will
be increasingly important. The problem of developing lower bounds for data
access complexity has been modeled using the formalism of Hong & Kung's
red/blue pebble game for computational directed acyclic graphs (CDAGs).
However, previously developed approaches to lower bounds analysis for the
red/blue pebble game are very limited in effectiveness when applied to CDAGs of
real programs, with computations comprised of multiple sub-computations with
differing DAG structure. We address this problem by developing an approach for
effectively composing lower bounds based on graph decomposition. We also
develop a static analysis algorithm to derive the asymptotic data-access lower
bounds of programs, as a function of the problem size and cache size
Two scenarios for avalanche dynamics in inclined granular layers
We report experimental measurements of avalanche behavior of thin granular
layers on an inclined plane for low volume flow rate. The dynamical properties
of avalanches were quantitatively and qualitatively different for smooth glass
beads compared to irregular granular materials such as sand. Two scenarios for
granular avalanches on an incline are identified and a theoretical explanation
for these different scenarios is developed based on a depth-averaged approach
that takes into account the differing rheologies of the granular materials.Comment: 4 pages, 4 figures, accepted to Phys. Rev. Let
Event Stream Processing with Multiple Threads
Current runtime verification tools seldom make use of multi-threading to
speed up the evaluation of a property on a large event trace. In this paper, we
present an extension to the BeepBeep 3 event stream engine that allows the use
of multiple threads during the evaluation of a query. Various parallelization
strategies are presented and described on simple examples. The implementation
of these strategies is then evaluated empirically on a sample of problems.
Compared to the previous, single-threaded version of the BeepBeep engine, the
allocation of just a few threads to specific portions of a query provides
dramatic improvement in terms of running time
Lattice QCD study of a five-quark hadronic molecule
We compute the ground-state energies of a heavy-light K-Lambda like system as
a function of the relative distance r of the hadrons. The heavy quarks, one in
each hadron, are treated as static. Then, the energies give rise to an
adiabatic potential Va(r) which we use to study the structure of the five-quark
system. The simulation is based on an anisotropic and asymmetric lattice with
Wilson fermions. Energies are extracted from spectral density functions
obtained with the maximum entropy method. Our results are meant to give
qualitative insight: Using the resulting adiabatic potential in a Schroedinger
equation produces bound state wave functions which indicate that the ground
state of the five-quark system resembles a hadronic molecule, whereas the first
excited state, having a very small rms radius, is probably better described as
a five-quark cluster, or a pentaquark. We hypothesize that an all light-quark
pentaquark may not exist, but in the heavy-quark sector it might, albeit only
as an excited state.Comment: 11 pages, 15 figures, 4 table
LIGO End-to-End simulation Program
A time-domain simulation program has been developed to provide an accurate description of interferometric gravitational wave detectors. This is being utilized to build a model of LIGO with the aim of aiding in the shakedown and integration of the interferometer subsystems, and ultimately the optimization of detector sensitivity
Dynamics and stress in gravity driven granular flow
We study, using simulations, the steady-state flow of dry sand driven by
gravity in two-dimensions. An investigation of the microscopic grain dynamics
reveals that grains remain separated but with a power-law distribution of
distances and times between collisions.
While there are large random grain velocities, many of these fluctuations are
correlated across the system and local rearrangements are very slow. Stresses
in the system are almost entirely transfered by collisions and the structure of
the stress tensor comes almost entirely from a bias in the directions in which
collisions occur.Comment: 4 pages, 3 eps figures, RevTe
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