2,157 research outputs found
Potential dietary feed additives with antibacterial effects and their impact on performance of weaned piglets: A meta-analysis
This meta-analysis evaluated the use of potential dietary feed additives (pDFA) with antibacterial effects and their impact on the perfomance of weaned piglets. Twenty-three peer-reviewed in vivo studies, comprising 50 trials, were identified between January 2010 and January 2017. The pDFA in these studies could be grouped in 5 classes: antimicrobial peptides, chitosan, lysozyme, medium chain fatty acids/ triglycerides and plant extracts. Mixed-effect meta-analyses with type of pDFA as fixed effect were performed for the growth parameters ‘average daily gain’ (ADG) and ‘feed conversion ratio’ (FCR), which are the two most important and used economic performance parameters for farmers.
For each class of pDFA, results of the meta-analysis showed significantly higher average daily gain in the group with pDFA compared to the negative control group, while no significant difference with the positive control group was observed. Furthermore, a positive effect on FCR was found, i.e. significantly less feed was needed to gain 1 kg of body weight in the group with pDFA compared to the negative control group. No significant differences with positive control groups were observed for each class of pDFA, except for plant extracts, where the FCR was also significantly reduced in the treatment group. These results suggest that pDFA could reduce the use of antimicrobials without significant negative effects on performance indicators
Potential dietary feed additives with antibacterial effects and their impact on performance of weaned piglets : a meta-analysis
This meta-analysis evaluated the use of potential dietary feed additives (pDFA) with antibacterial effects and their impact on the perfomance of weaned piglets. Twenty-three peer-reviewed in vivo studies, comprising 50 trials, were identified between January 2010 and January 2017. The pDFA in these studies could be grouped in 5 classes: antimicrobial peptides, chitosan, lysozyme, medium chain fatty acids/triglycerides and plant extracts. Mixed-effect meta-analyses with type of pDFA as fixed effect were performed for the growth parameters 'average daily gain' (ADG) and 'feed conversion ratio' (FCR), which are the two most important and used economic performance parameters for farmers.
For each class of pDFA, results of the meta-analysis showed significantly higher average daily gain in the group with pDFA compared to the negative control group, while no significant difference with the positive control group was observed. Furthermore, a positive effect on FCR was found, i.e. significantly less feed was needed to gain 1 kg of body weight in the group with pDFA compared to the negative control group. No significant differences with positive control groups were observed for each class of pDFA, except for plant extracts, where the FCR was also significantly reduced in the treatment group. These results suggest that pDFA could reduce the use of antimicrobials without significant negative effects on performance indicators
Optical properties of tungsten thin films perforated with a bidimensional array of subwavelength holes
We present a theorical investigation of the optical transmission of a
dielectric grating carved in a tungsten layer. For appropriate wavelengths
tungsten shows indeed a dielectric behaviour. Our numerical simulations leads
to theoretical results similar to those found with metallic systems studied in
earlier works. The interpretation of our results rests on the idea that the
transmission is correlated with the resonant response of eigenmodes coupled to
evanescent diffraction orders.Comment: 4 pages, 3 figure
How Predictability of Feeding Patches Affects Home Range and Foraging Habitat Selection in Avian Social Scavengers?
Relation between hospital orthopaedic specialisation and outcomes in patients aged 65 and older: retrospective analysis of US Medicare data
Objective To explore the relation between hospital orthopaedic specialisation and postoperative outcomes after total hip or knee replacement surgery
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Antibiotic stewardship implementation and patient-level antibiotic use at hospitals with and without on-site Infectious Disease specialists.
Many US hospitals lack Infectious Disease (ID) specialists, which may hinder antibiotic stewardship efforts. We sought to compare patient-level antibiotic exposure at Veterans Health Administration (VHA) hospitals with and without an on-site ID specialist, defined as an ID physician and/or ID pharmacist. This retrospective VHA cohort included all acute-care patient-admissions during 2016. A mandatory survey was used to identify hospitals' antibiotic stewardship processes and their access to an on-site ID specialist. Antibiotic use was quantified as days of therapy (DOT) per days-present and categorized based on National Healthcare Safety Network definitions. A negative binomial regression model with risk adjustment was used to determine the association between presence of an on-site ID specialist and antibiotic use at the level of patient-admissions. Eighteen of 122 (14.8%) hospitals lacked an on-site ID specialist; there were 525,451 (95.8%) admissions at ID hospitals and 23,007 (4.2%) at non-ID sites. In the adjusted analysis, presence of an ID specialist was associated with lower total inpatient antibacterial use [OR 0.92, (95% CI, 0.85-0.99)]. Presence of an ID specialist was also associated with lower use of broad-spectrum antibacterials [OR 0.61 (95% CI, 0.54-0.70)] and higher narrow-spectrum beta-lactam use [OR 1.43 (95% CI, 1.22-1.67)]. Total antibacterial exposure (inpatient plus post-discharge) was lower among patients at ID versus non-ID sites [OR 0.92 (95% CI, 0.86-0.99)]. Patients at hospitals with an ID specialist received antibiotics in a way more consistent with stewardship principles. The presence of an ID specialist may be important to effective antibiotic stewardship
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Antibiotic Stewardship Implementation and Antibiotic Use at Hospitals With and Without On-site Infectious Disease Specialists.
BackgroundMany US hospitals lack infectious disease (ID) specialists, which may hinder antibiotic stewardship efforts. We sought to compare patient-level antibiotic exposure at Veterans Health Administration (VHA) hospitals with and without an on-site ID specialist, defined as an ID physician and/or ID pharmacist.MethodsThis retrospective VHA cohort included all acute-care patient admissions during 2016. A mandatory survey was used to identify hospitals' antibiotic stewardship processes and their access to an on-site ID specialist. Antibiotic use was quantified as days of therapy per days present and categorized based on National Healthcare Safety Network definitions. A negative binomial regression model with risk adjustment was used to determine the association between presence of an on-site ID specialist and antibiotic use at the level of patient admissions.ResultsEighteen of 122 (14.8%) hospitals lacked an on-site ID specialist; there were 525 451 (95.8%) admissions at ID hospitals and 23 007 (4.2%) at non-ID sites. In the adjusted analysis, presence of an ID specialist was associated with lower total inpatient antibacterial use (odds ratio, 0.92; 95% confidence interval, .85-.99). Presence of an ID specialist was also associated with lower use of broad-spectrum antibacterials (0.61; .54-.70) and higher narrow-spectrum β-lactam use (1.43; 1.22-1.67). Total antibacterial exposure (inpatient plus postdischarge) was lower among patients at ID versus non-ID sites (0.92; .86-.99).ConclusionsPatients at hospitals with an ID specialist received antibiotics in a way more consistent with stewardship principles. The presence of an ID specialist may be important to effective antibiotic stewardship
Brane matter, hidden or mirror matter, their various avatars and mixings: many faces of the same physics
Numerous papers deal with the phenomenology related to photon-hidden photon
kinetic mixing and with the effects of a mass mixing on particle-hidden
particle oscillations. In addition, recent papers underline the existence of a
geometrical mixing between branes which would allow a matter swapping between
branes. These approaches and their phenomenologies are reminiscent of each
other but rely on different physical concepts. In the present paper, we suggest
there is no rivalry between these models, which are probably many faces of the
same physics. We discuss some phenomenological consequences of a global
framework.Comment: 9 pages. Typo corrected. Published in European Physical Journal
Exciton swapping in a twisted graphene bilayer as a solid-state realization of a two-brane model
It is shown that exciton swapping between two graphene sheets may occur under
specific conditions. A magnetically tunable optical filter is described to
demonstrate this new effect. Mathematically, it is shown that two turbostratic
graphene layers can be described as a "noncommutative" two-sheeted
(2+1)-spacetime thanks to a formalism previously introduced for the study of
braneworlds in high energy physics. The Hamiltonian of the model contains a
coupling term connecting the two layers which is similar to the coupling
existing between two braneworlds at a quantum level. In the present case, this
term is related to a K-K' intervalley coupling. In addition, the experimental
observation of this effect could be a way to assess the relevance of some
theoretical concepts of the braneworld hypothesis.Comment: 15 pages, 3 figures, final version published in European Physical
Journal
Optical structure and function of the white filamentary hair covering the edelweiss bracts
The optical properties of the inflorescence of the high-altitude
''Leontopodium nivale'' subsp. ''alpinum'' (edelweiss) is investigated, in
relation with its submicrometer structure, as determined by scanning electron
microscopy. The filaments forming the hair layer have been found to exhibit an
internal structure which may be one of the few examples of a photonic structure
found in a plant. Measurements of light transmission through a self-supported
layer of hair pads taken from the bracts supports the idea that the wooly layer
covering the plant absorbs near-ultraviolet radiation before it reaches the
cellular tissue. Calculations based on a photonic-crystal model provides
insight on the way radiation can be absorbed by the filamentary threads.Comment: 9 pages, 13 figures. Published pape
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