Study on Sedation with Local Analgesia in Calves

Abstract. The effect of sedatives and analgesics on heart rate, respiration rate and rectal temperature were observed. Heart rate and respiration rate significantly decreased during sedation with xylazine hydrochloride plus 2% lignocaine hydrochloride or 0.5% bupivacaine hydrochloride. A significantly decreased heart rate and respiration rate also found during sedation with diazepam plus 2% lignocaine hydrochloride or 0.5% bupivacaine hydrochloride. Two percent lignocaine hydrochloride showed short onset, rapid spreading and no side effect. Duration of analgesia was longer with 0.5 % bupivacaine hydrochloride (55.88±1.58 min in Group B and 48±11.25 min in Group D) compared to 2% lignocaine hydrochloride (39.60±5.77 min in Group A and 43.6±5.81 min in Group C). Xylazine hydrochloride showed short onset and long duration of sedation compared to diazepam. So for herniorraphy, xylazine hydrochloride can be used as a better sedative while 0.5 % bupivacaine hydrochloride can be used as a local analgesic for longer duration of action.Key Words: lignocaine hydrochloride, sedation, analgesiaNC Sarker et al/Animal Production 13(3):191-197 (2011

A quantitative model for disruption mitigation in a supply chain

© 2016 Elsevier B.V. In this paper, a three-stage supply chain network, with multiple manufacturing plants, distribution centers and retailers, is considered. For this supply chain system we develop three different approaches, (i) an ideal plan for an infinite planning horizon and an updated plan if there are any changes in the data, (ii) a predictive mitigation planning approach for managing predictive demand changes, which can be predicted in advance by using an appropriate tool, and (iii) a reactive mitigation plan, on a real-time basis, for managing sudden production disruptions, which cannot be predicted in advance. In predictive mitigation planning, we develop a fuzzy inference system (FIS) tool to predict the changes in future demand over the base forecast and the supply chain plan is revised accordingly well in advance. In reactive mitigation planning, we formulate a quantitative model for revising production and distribution plans, over a finite future planning period, while minimizing the total supply chain cost. We also consider a series of sudden disruptions, where a new disruption may or may not affect the recovery plans of earlier disruptions and which consequently require plans to be revised after the occurrence of each disruption on a real-time basis. An efficient heuristic, capable of dealing with sudden production disruptions on a real-time basis, is developed. We compare the heuristic results with those obtained from the LINGO optimization software for a good number of randomly generated test problems. Also, some numerical examples are presented to explain both the usefulness and advantages of the proposed approaches

Managing supply disruption in a three-tier supply chain with multiple suppliers and retailers

© 2014 IEEE. In this paper, a supply disruption management model is introduced in a three-tier supply chain with multiple suppliers and retailers, where the system may face sudden disruption in its raw material supply. At first, we formulated a mathematical model for ideal conditions and then reformulated it to revise the supply, production and delivery plan after the occurrence of a disruption, for a future period, to recover from the disruption. Here, the objective is to minimize the total cost during the recovery time window while being subject to supply, capacity, demand, and delivery constraints. We have also proposed an efficient heuristic to solve the model and the results have been compared, with another established solution approach, for a good number of randomly generated test problems. The comparison showed the consistent performance of our developed heuristic. This paper also presents some numerical examples to explain the usefulness of the proposed approach

Study on Sedation with Local Analgesia in Calves

. The effect of sedatives and analgesics on heart rate, respiration rate and rectal temperature were observed. Heart rate and respiration rate significantly decreased during sedation with xylazine hydrochloride plus 2% lignocaine hydrochloride or 0.5% bupivacaine hydrochloride. A significantly decreased heart rate and respiration rate also found during sedation with diazepam plus 2% lignocaine hydrochloride or 0.5% bupivacaine hydrochloride. Two percent lignocaine hydrochloride showed short onset, rapid spreading and no side effect. Duration of analgesia was longer with 0.5 % bupivacaine hydrochloride (55.88±1.58 min in Group B and 48±11.25 min in Group D) compared to 2% lignocaine hydrochloride (39.60±5.77 min in Group A and 43.6±5.81 min in Group C). Xylazine hydrochloride showed short onset and long duration of sedation compared to diazepam. So for herniorraphy, xylazine hydrochloride can be used as a better sedative while 0.5 % bupivacaine hydrochloride can be used as a local analgesic for longer duration of action

A mathematical modelling approach for managing sudden disturbances in a three-tier manufacturing supply chain

© 2019, Springer Science+Business Media, LLC, part of Springer Nature. This paper aims to develop a recovery planning approach in a three-tier manufacturing supply chain, which has a single supplier, manufacturer, and retailer under an imperfect production environment, in which we consider three types of sudden disturbances: demand fluctuation, and disruptions to production and raw material supply, which are not known in advance. Firstly, a mathematical model is developed for generating an ideal plan under imperfect production for a finite planning horizon while maximizing total profit, and then we re-formulate the model to generate the recovery plan after happening of each sudden disturbance. Considering the high commercial cost and computational intensity and complexity of this problem, we propose an efficient heuristic, to obtain a recovery plan, for each disturbance type, for a finite future period, after the occurrence of a disturbance. The heuristic solutions are compared with a standard solution technique for a considerable number of random test instances, which demonstrates the trustworthy performance of the developed heuristics. We also develop another heuristic for managing the combined effects of multiple sudden disturbances in a period. Finally, a simulation approach is proposed to investigate the effects of different types of disturbance events generated randomly. We present several numerical examples and random experiments to explicate the benefits of our developed approaches. Results reveal that in the event of sudden disturbances, the proposed mathematical and heuristic approaches are capable of generating recovery plans accurately and consistently

Prospects and Evaluation of an Integrated Extension Model designed for Anthrax-free Area Development

The main purpose of this study wasto assess and evaluate anIntegrated Extension Modelto improve the overall knowledge, attitude and practice habits of community people over a sustained period.The survey questionnaire results have indicated that the various sources of anthrax message dissemination had played a significant role in the study. Among those responsible for disseminating the information, it was realized that studentsserving in the role of message disseminators played the most significant role (15%) indelivering the anthrax-related key information to the community. Majority community members (97.5%) were made aware of the nature, occurrence, public health importance, and management of the disease. Theirdangerous habits and attitudes toward slaughtering of sick animals were reduced (\u3c30%). The attention of local administration and the law enforcement agency focused distinctively on the issue of animal slaughter. Vaccination and clinical records reveal that the percentage of vaccination coverage was increased from 40% to 85% andthe percentage of farmers who can diagnose anthrax has been increased from 30% to 40%.On the other hand, their poor economic background together with the dispersed settlement nature of the farmers was the main gaps identified that continued to force them to slaughter infected animals, sell their products and to consequently concealthat information, all issues that are required to be addressed in the future. Based on the research findings, it can be concluded that this modelis an efficient, effective and suitable method to raise awareness levels in a large communitywith regards to a zoonotic disease like anthrax

Хліб: семантика в контексті народного етикету Середнього Полісся

У статті представлено дослідження міфологічних уявлень, пов’язаних з хлібом. Розглянуто особливості функціонування, семантизації цього культурного явища та його номінацію.Статья представляет исследование мифологических представлений, связанных с хлебом. Рассмотрено особенности функционирования, семантизации этого культурного явления и его номинацию.The article presents the study of the mythological presentations, what a connected with bread. The considered particularity of the operation, semantization this cultural phenomena and its nomination

Spatially explicit database on crop-livestock management, soil, climate, greenhouse gas emissions and mitigation potential for all of Bangladesh

Acknowledgments: The International Maize and Wheat Improvement Center (CIMMYT) carried out this work with support of the CGIAR research program on Climate Change, Agriculture and Food Security (CCAFS) and the Climate Services for Resilient Development (CSRD; https://ccafs.cgiar.org/research/projects/climate-services-resilient-development-south-asia) for South Asia project supported by USAID. This work was also supported by the USAID and Bill and Melinda Gates Foundation (BMGF) supported Cereal Systems Initiative for South Asia (CSISA; https://csisa.org) CCAFS’ work is supported by CGIAR Fund Donors and through bilateral funding agreements. For details please visit https://ccafs.cgiar.org/donors. The views expressed in this paper cannot be taken to reflect the official opinions of CCAFS, USAID, or BMGF, and shall not be used for advertising.Peer reviewedPublisher PD

Quantifying opportunities for greenhouse gas emissions mitigation using big data from smallholder crop and livestock farmers across Bangladesh

Funding Information: The International Maize and Wheat Improvement Center (CIMMYT) carried out this work with support of the CGIAR research program on Climate Change, Agriculture and Food Security (CCAFS) and the Climate Services for Resilient Development (CSRD; https://ccafs.cgiar.org/research/projects/climate-services-resilient-development-south-asia ) for South Asia project supported by USAID . This work was also supported by the USAID and Bill and Melinda Gates Foundation (BMGF) supported Cereal Systems Initiative for South Asia (CSISA; https://csisa.org ). CCAFS' work is supported by CGIAR Fund Donors and through bilateral funding agreements. For details please visit https://ccafs.cgiar.org/donors . The views expressed in this paper cannot be taken to reflect the official opinions of CCAFS, USAID, or BMGF, and shall not be used for advertising. We sincerely acknowledge the input and support provided by various stakeholders in Bangladesh during stakeholder meetings. We are thankful to Robel Takele and Sanjay Pothireddy for graphics assistance.Peer reviewedPublisher PD

A Rapid Assessment of the Quality of Neonatal Healthcare in Kilimanjaro Region, Northeast Tanzania.

While child mortality is declining in Africa there has been no evidence of a comparable reduction in neonatal mortality. The quality of inpatient neonatal care is likely a contributing factor but data from resource limited settings are few. The objective of this study was to assess the quality of neonatal care in the district hospitals of the Kilimanjaro region of Tanzania. Clinical records were reviewed for ill or premature neonates admitted to 13 inpatient health facilities in the Kilimanjaro region; staffing and equipment levels were also assessed. Among the 82 neonates reviewed, key health information was missing from a substantial proportion of records: on maternal antenatal cards, blood group was recorded for 52 (63.4%) mothers, Rhesus (Rh) factor for 39 (47.6%), VDRL for 59 (71.9%) and HIV status for 77 (93.1%). From neonatal clinical records, heart rate was recorded for3 (3.7%) neonates, respiratory rate in 14, (17.1%) and temperature in 33 (40.2%). None of 13 facilities had a functioning premature unit despite calculated gestational age <36 weeks in 45.6% of evaluated neonates. Intravenous fluids and oxygen were available in 9 out of 13 of facilities, while antibiotics and essential basic equipment were available in more than two thirds. Medication dosing errors were common; under-dosage for ampicillin, gentamicin and cloxacillin was found in 44.0%, 37.9% and 50% of cases, respectively, while over-dosage was found in 20.0%, 24.2% and 19.9%, respectively. Physician or assistant physician staffing levels by the WHO indicator levels (WISN) were generally low. Key aspects of neonatal care were found to be poorly documented or incorrectly implemented in this appraisal of neonatal care in Kilimanjaro. Efforts towards quality assurance and enhanced motivation of staff may improve outcomes for this vulnerable group