Ceti dirigenti, societ\ue0 ed economia del quartiere Kalsa nei secoli XIV e Xv

Nel Trecento la Kalsa era un borgo marinaresco, come attesta la toponomastica, abitato da mercanti stranieri. Folta era la comunit\ue0 pisana legata alla chiesa e al monastero di San Francesco. Il volto del quartiere cambi\uf2 profondamente quando i Chiaromonte s'insediarono alla Kalsa e vi edificarono un imponente palazzo, detto Steri. In seguito alla loro ascesa politica, il quartiere divenne una zona residenziale, dove vivevano famiglie alleate con i potenti signori. Dal censimento effettuato nel 1480 emerge la presenza d'importanti burocrati, giuristi e note famiglie nobiliari che costruirono eleganti palazzi in stile gotico catalano

Exact regularized point particle method for multi-phase flows in the two-way coupling regime

Particulate flows have been largely studied under the simplifying assumptions of one-way coupling regime where the disperse phase do not react-back on the carrier fluid. In the context of turbulent flows, many non trivial phenomena such as small scales particles clustering or preferential spatial accumulation have been explained and understood. A more complete view of multiphase flows can be gained calling into play two-way coupling effects, i.e. by accounting for the inter-phase momentum exchange between the carrier and the suspended phase, certainly relevant at increasing mass loading. In such regime, partially investigated in the past by the so-called Particle In Cell (PIC) method, much is still to be learned about the dynamics of the disperse phase and the ensuing alteration of the carrier flow. In this paper we present a new methodology rigorously designed to capture the inter-phase momentum exchange for particles smaller than the smallest hydrodynamical scale, e.g. the Kolmogorov scale in a turbulent flow. In fact, the momentum coupling mechanism exploits the unsteady Stokes flow around a small rigid sphere where the transient disturbance produced by each particle is evaluated in a closed form. The particles are described as lumped, point masses which would lead to the appearance of singularities. A rigorous regularization procedure is conceived to extract the physically relevant interactions between particles and fluid which avoids any "ah hoc" assumption. The approach is suited for high efficiency implementation on massively parallel machines since the transient disturbance produced by the particles is strongly localized in space around the actual particle position. As will be shown, hundred thousands particles can therefore be handled at an affordable computational cost as demonstrated by a preliminary application to a particle laden turbulent shear flow.Comment: Submitted to Journal of Fluid Mechanics, 56 pages, 15 figure

Istituzioni ecclesiastiche e potere regio nel mediterraneo medievale. Scritti per Salvatore Fodale

Il volume è un omaggio degli allievi al professore Salvatore Fodale. Il filo conduttore sono le Istituzioni ecclesiastiche e il potere regio tra l’età normanna e la fine del Medioevo. Uno spazio particolare è dedicato alla città di Messina, al centro dei saggi sulla religiosità tra Oriente e Occidente e su Raimondo Puyolis, arcivescovo catalano nel Trecento. Il rapporto tra Istituzioni ecclesiastiche e potere regio emerge negli articoli su Papato e propaganda di crociata nel Duecento e sul monastero di Santa Maria del Bosco di Calatamauro. Viene, inoltre, esaminata la complessa relazione tra Martino il Giovane e la comunità ebraica siciliana. Il regno di Alfonso il Magnanimo fa da sfondo ai saggi sul memoriale della Camera reginale, al tempo della moglie Maria di Castiglia, e sulla Descendencia dominorum Regni Sicilie di Pau Rossell, codice commissionato a Valencia tra il 1437 e il 1438. In un mondo a parte sembrano vivere i La Grua, baroni di Carini, non inseriti nel sistema di potere della monarchia

Supervisory Control for Behavior Composition

We relate behavior composition, a synthesis task studied in AI, to supervisory control theory from the discrete event systems field. In particular, we show that realizing (i.e., implementing) a target behavior (e.g., a house surveillance system) by suitably coordinating a collection of available behaviors (e.g., doors, lights, cameras, etc.) amounts to imposing a supervisor onto a special discrete event system. Such a link allows us to leverage on the solid foundations and extensive work on discrete event systems, including borrowing tools and ideas from it

Il monastero di Santa Caterina e la citt\ue0 di Palermo

Il monastero femminile di Santa Caterina fu edificato ai primi del Trecento nel quartiere Cassaro di Palermo per volere di Benvenuta, figlia di Ruggero Mastrangelo, nominato capitano all'indomani del Vespro, e vedova del ghibellino toscano Guglielmo Aldobrandeschi, conte di Santa Fiora. Priva di figli, la contessa dot\uf2 il monastero di un cospicuo patrimonio immobiliare, dislocato sia all'interno della citt\ue0 che nel suo territorio, e lo affid\uf2 ai Domenicani. Nei secoli XIV e XV Santa Caterina fu il monastero pi\uf9 ricco di Palermo ed ebbe uno stretto rapporto con la citt\ue0, che prima della costruzione del nuovo Palazzo Pretorio si riuniva nella sala capitolare. A Santa Caterina vissero monache appartenenti a famiglie nobiliari, come gli Abbatellis, al ceto cavalleresco e anche la figlia del pittore Guglielmo da Pesaro. Nel Quattrocento si verificarono conflitti all'interno del capitolo monastico e contrasti tra i Domenicani e l'arcivescovo di Palermo per il controllo del monastero

Phenotypic and genetic analysis of udder health using SCC in Valle del Belice dairy sheep

Intramammary infections (IMI) are a complex of inflammatory diseases which are defined as an inflammation of the mammary gland resulting from the introduction and multiplication of pathogenic micro-organisms

Applications of Monte Carlo methods to special radiotherapeutic techniques

Monte Carlo (MC) methods are considered one of the most powerful and precise approaches to study and solve medical physics issues. They, indeed, can be applied in all the situations where to use deterministic algorithms is infeasible or impossible. Surprising improvements in computer technology have promoted a wide diffusion of this technique, giving rise to the born of several Monte Carlo codes, such as the GEANT4 toolkit. In this paper we show some of the applications we developed using GEANT4. In particular, the simulation of two different radiotherapy techniques, such as proton/ion therapy and stereotactic radiosurgery will be discussed. In the first case we show the main features of our last public version of the GEANT4 Hadrontherapy program, also discussing the issues related to the nuclear fragmentation. In the second case, we show the procedures followed for the simulation of a Gamma Knife device, in order to validate the Treatment Planning System (TPS) used for the dose computation

Pollen Streptomyces Produce Antibiotic That Inhibits the Honey Bee Pathogen Paenibacillus larvae

Humans use natural products to treat disease; similarly, some insects use natural products produced by Actinobacteria to combat infectious pathogens. Honey bees, Apis mellifera, are ecologically and economically important for their critical role as plant pollinators and are host to diverse and potentially virulent pathogens that threaten hive health. Here, we provide evidence that Actinobacteria that can suppress pathogenic microbes are associated with A. mellifera. We show through culture-dependent approaches that Actinobacteria in the genus Streptomyces are commonly isolated from foraging bees, and especially common in pollen stores. One strain, isolated from pollen stores, exhibited pronounced inhibitory activity against Paenibacillus larvae, the causative agent of American foulbrood. Bioassay-guided HPLC fractionation, followed by NMR and mass spectrometry, identified the known macrocyclic polyene lactam, piceamycin that was responsible for this activity. Further, we show that in its purified form, piceamycin has potent inhibitory activity toward P. larvae. Our results suggest that honey bees may use pollen-derived Actinobacteria and their associated small molecules to mediate colony health. Given the importance of honey bees to modern agriculture and their heightened susceptibility to disease, the discovery and development of antibiotic compounds from hives could serve as an important strategy in supporting disease management within apiaries.National Institute for Health/[U19 AI142720]/NIH/Estados UnidosNational Institute of Food and Agriculture/[WISO1321]/NIFA/Estados UnidosUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Básicas::Centro de Investigación en Estructuras Microscópicas (CIEMIC)UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Básicas::Centro de Investigación en Biología Celular y Molecular (CIBCM