503 research outputs found
Penerapan Model Pembelajaran Kooperatif Tipe Make a Match Untuk Meningkatkan Hasil Belajar IPS Siswa Kelas IV Sdn 11 Dompas Kecamatan Bukit Batu
The research aims to improve the student\u27s learning result of social studies by applying cooperatif learning model make a match.The problem of this research is the weakness of student\u27s learning result of social studies from the fourth grade students of SD Negeri 11 Dompas,there are 20 students. The KKM of this school is 66, only 8 students (40.00%) were above the KKM, while 12 students (60.00%) are under the KKM, with the average value of the class is 64.70. This research is a classroom action research (CAR) by applying cooperative learning model make a match.At the first meeting, the activities of teachers percentage 54.16% enough category, then a second meeting increased to 70.83% both categories. Then at the first meeting of the second cycle increased to 83.33% category very good.the second meeting up again with a percentage of 91.66%. increased student activity each meeting. At the first meeting of the first cycle of student activity percentage is 41.66% enough category, then the second meeting of the second cycle increased to 66.66% both categories. At the first meeting of the second cycle increased to 83.33% very good category. At the second meeting increased again the percentage is 87.50% (very good). The average value of the basic score before implementation of cooperative learning make a match is 64.70. in the UHI learning result was 74.50 and then on the second cycle increased again which can be seen in UHII replay value with an average value of students was 79.50
Ag-based thick-film front metallization of silicon solar cells
The evolution of microstructure and electrical properties of silver-based thick-film metallizations of silicon solar cells prepared by infrared firing processes has been ivestigated. The performance of the cells are shown to be dependent on several dynamical and diffusive phenomena. In particular, the sintering of silver grains, silver diffusion in the glassand the flow of gas at the metal/silicon interface strongly affect important characteristics of the cells such as sheet and contatct resistivities and the adhesion of fingers and bus bars. The existance of an optimum value of the peak firing temperature is observed and explained in terms of competitive phenomena occuring at the metal/silicon interface. Moreover it is shown that IR firing treatments require aa careful consideration of the sequence of printing anf firing steps. The features of heat treatments performed in conveyor belt furnaces using Joule and infrared sources are compared
JNK1 ablation improves pancreatic β-cell mass and function in db/db diabetic mice without affecting insulin sensitivity and adipose tissue inflammation
The cJun N-terminal Kinases (JNK) emerged as a major link between obesity and insulin resistance, but their role in the loss of pancreatic β-cell mass and function driving the progression from insulin resistance to type-2 diabetes and in the complications of diabetes was not investigated to the same extent. Furthermore, it was shown that pan-JNK inhibition exacerbates kidney damage in the db/db model of obesity-driven diabetes. Here we investigate the role of JNK1 in the db/db model of obesity-driven type-2 diabetes. Mice with systemic ablation of JNK1 (JNK1−/−) were backcrossed for more than 10 generations in db/+ C57BL/KS mice to generate db/db-JNK1−/− mice and db/db control mice. To define the role of JNK1 in the loss of β-cell mass and function occurring during obesity-driven diabetes we performed comprehensive metabolic phenotyping, evaluated steatosis and metabolic inflammation, performed morphometric and cellular composition analysis of pancreatic islets, and evaluated kidney function in db/db-JNK1−/− mice and db/db controls. db/db-JNK1−/− mice and db/db control mice developed insulin resistance, fatty liver, and metabolic inflammation to a similar extent. However, db/db-JNK1−/− mice displayed better glucose tolerance and improved insulin levels during glucose tolerance test, higher pancreatic insulin content, and larger pancreatic islets with more β-cells than db/db mice. Finally, albuminuria, kidney histopathology, kidney inflammation and oxidative stress in db/db-JNK1−/− mice and in db/db mice were similar. Our data indicate that selective JNK1 ablation improves glucose tolerance in db/db mice by reducing the loss of functional β-cells occurring in the db/db mouse model of obesity-driven diabetes, without significantly affecting metabolic inflammation, steatosis, and insulin sensitivity. Furthermore, we have found that, differently from what previously reported for pan-JNK inhibitors, selective JNK1 ablation does not exacerbate kidney dysfunction in db/db mice. We conclude that selective JNK1 inactivation may have a superior therapeutic index than pan-JNK inhibition in obesity-driven diabetes
Triangular Sierpinski Microwave Band-Stop Resonators for K-Band Filtering
Triangular resonators re-shaped with Sierpinski geometry were designed, manufactured, and tested for potential applications in the K-Band. Prototypes of band-stop filters working around 20 GHz and 26 GHz, interesting for RADAR and satellite communications, were studied in a coplanar waveguide (CPW) configuration. Single and coupled structures were analyzed to give evidence for: (i) the tuning of the resonance frequency by increasing the internal complexity of the triangle and (ii) resonance enhancement when coupled structures are considered. The exploited devices were part of the more extended family of metamaterial-inspired structures, and they were studied for their heuristic approach to the prediction of the spectrum using experimental results supported by electromagnetic simulations. As a result, a Sierpinski resonator, not only fed into but also fully embedded into a CPW environment, had a frequency response that was not easily determined by classical theoretical approaches
MEMS-Switched Triangular and U-Shaped Band-Stop Resonators for K-Band Operation
Triangular resonators re-shaped into Sierpinski geometry and U-shaped resonators were designed, linking them with single-pole-double-through (SPDT) RF MEMS switches to provide frequency tuning for potential applications in the K-Band. Prototypes of band-stop narrowband filters working around 20 GHz and 26 GHz, interesting for RADAR and satellite communications, were studied in a coplanar waveguide (CPW) configuration, and the tuning was obtained by switching between two paths of the devices loaded with different resonators. As a result, dual-band operation or fine-tuning could be obtained depending on the choice of the resonator, acting as a building block. The studied filters belong to the more general group of devices inspired by a metamaterial design
Lipid peroxidation and cyclooxygenase-2 activity in human hepatocellular carcinoma cell lines with and without multiple drug resistance: correlation with cell growth
Pediatric sinonasal neuroendocrine carcinoma following treatment for retinoblastoma. Human Pathology, 2009; 40:750-755.
Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases.
The gold standard for a definitive diagnosis of Parkinson disease (PD) is the pathologic finding of aggregated α-synuclein into Lewy bodies and for Alzheimer disease (AD) aggregated amyloid into plaques and hyperphosphorylated tau into tangles. Implicit in this clinicopathologic-based nosology is the assumption that pathologic protein aggregation at autopsy reflects pathogenesis at disease onset. While these aggregates may in exceptional cases be on a causal pathway in humans (e.g., aggregated α-synuclein in SNCA gene multiplication or aggregated β-amyloid in APP mutations), their near universality at postmortem in sporadic PD and AD suggests they may alternatively represent common outcomes from upstream mechanisms or compensatory responses to cellular stress in order to delay cell death. These 3 conceptual frameworks of protein aggregation (pathogenic, epiphenomenon, protective) are difficult to resolve because of the inability to probe brain tissue in real time. Whereas animal models, in which neither PD nor AD occur in natural states, consistently support a pathogenic role of protein aggregation, indirect evidence from human studies does not. We hypothesize that (1) current biomarkers of protein aggregates may be relevant to common pathology but not to subgroup pathogenesis and (2) disease-modifying treatments targeting oligomers or fibrils might be futile or deleterious because these proteins are epiphenomena or protective in the human brain under molecular stress. Future precision medicine efforts for molecular targeting of neurodegenerative diseases may require analyses not anchored on current clinicopathologic criteria but instead on biological signals generated from large deeply phenotyped aging populations or from smaller but well-defined genetic-molecular cohorts
Pediatric rhabdoid meningioma: a morphological, immunohistochemical, ultrastructural and molecular case study.
Near-field microwave techniques for micro – and nano - scale characterization in materials science
In this paper, the basic principles of Near-Field Microscopy will be reviewed with focus on the micro-
and nano-scale resolution configurations for material science measurements. Results on doping profile, dielectric
and magnetic properties will be presented, with details on the calibration protocols needed for quantitative estimation
of the dielectric constant and of the permeability
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