The Evolution of the Arts: Kuravanchi Dance Drama

No matter or energy can be created or destroyed. The law of physics is that it can only be transformed into another object or energy. It applicable to the arts also. Art can never suddenly emerge anew. It is influenced by different arts over a while and takes on the appearance of another art based on needs. Therefore, Evolution is the development of another art under the influence of other arts. Thus, the literary art of Kuravanchi has evolved into the art of drama coupling with the arts of music and dance. The purpose of this article is to analyze the organization of the Kuravanchi dance dramas and to observe whether the traces of the above arts can be found in them

Outcomes For Street Children and Youth Under Multidisciplinary Care in a Drop-In Centre in Tegucigalpa, Honduras

BACKGROUND: There is little evidence to describe the feasibility and outcomes of services for the care of street children and youth in low-income countries. AIMS: To describe the outcomes of a multidisciplinary case management approach delivered in a drop-in centre for street children and youth. METHODS: A longitudinal study of street children and youth followed in an urban drop-in centre. Four hundred (400) street children and youth received a multidisciplinary case management therapeutic package based on the community reinforcement approach. The main outcomes were changes in psychological distress, substance abuse and social situation scores. RESULTS: The median follow-up time for the cohort was 18 months. There were reductions in the levels of psychological distress (p = 0.0001) and substance abuse (p ≤ 0.0001) in the cohort as well as an improvement in the social situation of street children and youth (p = 0.0001). There was a main effect of gender (p < 0.001) and a significant interaction of gender over time (p < 0.001) on improvements in levels of psychological distress. Survival analysis showed that the probability of remaining on substances at 12 months was 0.76 (95% CI: 0.69-0.81) and 0.51 (95% CI: 0.42-0.59) at 24 months. At 12 months, fewer female patients remained using substances compared to male (p < 0.01). CONCLUSION: To be most effective, programmes and strategies for children and youth in street situations in developing countries should target both their health and social needs

A CASE REPORT OF PHENYTOIN AND CARBAMAZEPINE CROSS-REACTIVITY

ABSTRACTA case report of cross-reactivity between phenytoin and carbamazepine, a 63-year-old male patient was prescribed phenytoin for generalized seizuresand on the 15 day of therapy developed generalized maculopapular eruptions. Phenytoin was discontinued, and carbamazepine was administered.After 28 days, he developed fever, generalized rashes with ulcers in the oral cavity. Carbamazepine was withdrawn, and the patient was treatedsymptomatically.thKeywords: Phenytoin, Carbamazepine, Cross-reactivity

Treatment of acute ischemic stroke with recombinant tissue plasminogen activator: practice pattern among neurologists and physicians

Background: Stroke is an abrupt onset of a neurologic deficit due to a focal vascular disease. Treatment guidelines for acute ischemic stroke (AIS) within 4.5 hours of onset are thrombolysis with recombinant tissue plasminogen activator (rtPA). To determine the practice pattern of rtPA in the treatment of acute ischemic stroke among consultants using a questionnaire.Methods: A questionnaire based study was carried out from May to September 2015. Neurologists and physicians from Kolar and Bengaluru were given a questionnaire comprising of 21 questions, regarding the treatment of AIS with rtPA. The data was analyzed using descriptive statistics.Results: A total of 76.9% responded to the questionnaire, of which 18 were neurologists and 82 were physicians. An average of 4-5 AIS patients per month were seen by the doctors. Majority (72%) did not use rtPA, due to delay in patient reaching hospital or non-affordability of the drug. The consultants (66%) opined that rtPA was the best if patient arrived within 4.5 hours of onset of AIS. Only 34% consultants knew the correct score of AIS for administration of rtPA. The usage of penumbral imaging before thrombolysis was agreed by neurologists (58%) and physicians (34%). The IV+IA rtPA thrombolytic therapy produced highest rate of recanalization as expressed by neurologists (84%) and physicians (56%). Majority (80%) felt that use of rtPA beyond 4-6 hours had no beneficial effect. The adverse effects encountered were hypotension and bleeding.Conclusions: Neurologists and physicians opined that treatment with rtPA was effective in patients of AIS within 4.5 hours of onset, but the limitations were late arrival of patient to hospital and drug cost

Papaya Extract to Treat Dengue: A Novel Therapeutic Option?

Abstract Dengue is a viral disease that today affects a vast number of people in over 125 countries and is responsible for a sizable number of deaths. In the absence of an effective antiviral drug to treat the disease, various treatments are being investigated. Studies have indicated that the juice of the leaves of the Carica papaya plant from the family Caricaceae could help to increase the platelet levels in these patients. This review describes some of the published studies on this topic. The search was done independently by the two authors using PubMed, Google and the library database and included relevant articles of the last 10 years. A total of 7 studies were included in this review, which were one animal study, one case report, three case series and two randomized controlled trials. Although many of the studies and case reports published in literature lack adequate information, some of the studies do raise the possibility that this treatment could be an important option in the future. Further large-scale studies could establish the usefulness or ineffectiveness of this natural product in the treatment of dengue

Generic Paddy Plant Disease Detector (GP2D2): An Application of the Deep-CNN Model

Rice is the primary food for almost half of the world’s population, especially for the people of Asian countries. There is a demand to improve the quality and increase the quantity of rice production to meet the food requirements of the increasing population. Bulk cultivation and quality production of crops need appropriate technology assistance over manual traditional methods. In this work, six popular Deep-CNN architectures, namely AlexNet, VGG-19, VGG-16, InceptionV3, MobileNet, and ResNet-50, are exploited to identify the diseases in paddy plants since they outperform most of the image classification applications. These CNN models are trained and tested with Plant Village dataset for classifying the paddy plant images into one of the four classes namely, Healthy, Brown Spot, Hispa, or Leaf Blast, based on the disease condition. The performance of the chosen architectures is compared with different hyper parameter settings. AlexNet outperformed other convolutional neural networks (CNNs) in this multiclass classification task, achieving an accuracy of 89.4% at the expense of a substantial number of network parameters, indicating the large model size of AlexNet. For developing mobile applications, the ResNet-50 architecture was adopted over other CNNs, since it has a comparatively smaller number of network parameters and a comparable accuracy of 86.1%. A fine-tuned ResNet-50 architecture supported mobile app, “Generic Paddy Plant Disease Detector (GP2D2)” has been developed for the identification of most commonly occurring diseases in paddy plants. This tool will be more helpful for the new generation of farmers in bulk cultivation and increasing the productivity of paddy. This work will give insight into the performance of CNN architectures in rice plant disease detection task and can be extended to other plants too

A STUDY ON DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR THE ESTIMATION OF CEFPODOXIME IN BULK AND A PHARMACEUTICAL DOSAGE FORMS

A simple, rapid, precise, sensitive and, reproducible reverse phase high performance liquid chromatography (RP-HPLC) method has been developed for the quantitative analysis of Cefpodoxime in a pharmaceutical dosage form. Chromatographic separation of Cefpodoxime was achieved on Waters Alliance -2695, by using Luna Pheny Hexyl (250mm x 4.6mm, 5µm) column and the mobile phase containing 0.1% TEA adj pH-2.5 with OPA &amp; ACN in the ratio of 75:25% v/v. The flow rate was 1.0 ml/min, detection was carried out by absorption at 222nm using a photodiode array detector at ambient temperature. The number of theoretical plates and tailing factor for Cefpodoxime were NLT 2000 and should not be more than 2 respectively. The linearity of the method was excellent over the concentration range 7-105 µg/ml for Cefpodoxime respectively. The correlation coefficient was 0.999. % Relative standard deviation of peak areas of all measurements always less than 2.0. The proposed method was validated according to ICH guidelines.&nbsp; The method was found to be a simple, economical, suitable, precise, accurate &amp; robust method for quantitative analysis of Cefpodoxime and study of its stability

Electrooptic soft mode response of compounds exhibiting the antiferroelectric phase

We report measurements on the electrooptic response of thin samples (~2-5 &#956;m) of two antiferroelectric liquid crystals. All the phase transitions in these compounds can be very easily detected using this technique. We have been able to measure such an electrooptic effect for the first time in the antiferroelectric and smectic I&#8727; phases of a tolane compound. The response shows a relaxation at high frequencies (~10 KHz) and is at-tributed to a soft mode which produces an asymmetry in the molecular tilt in successive layers

Advancing conceptualisation of university entrepreneurial ecosystems: The role of knowledge-intensive entrepreneurial firms

University entrepreneurial ecosystems are increasingly important in facilitating innovation and entrepreneurial opportunities in today’s knowledge-based economies. However, we have an incomplete understanding of the demand side of university entrepreneurial ecosystems regarding the role of the entrepreneurial firm as the key user of university knowledge. We propose that use of university knowledge positively influences entrepreneurial firm performance and that the entrepreneurial firm’s resources and capabilities facilitate its ability to create value from university knowledge. We test our hypotheses on survey data of 3853 knowledge-intensive entrepreneurial firms from 10 European countries. Our study contributes to an increased understanding of the economic, societal and technological contributions of universities by empirically illustrating the role of firm resources and capabilities as moderators of value in university entrepreneurial ecosystems