2,294 research outputs found

    The Apollo 15 coarse fines (4-10 mm)

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    A new catalog of the Apollo 15 coarse fines particles is presented. Powell's macroscopic descriptions, resulting from his 1972 particle by particle binocular examination of all of the Apollo 15 4 to 10 mm fines samples, are retained. His groupings are also retained, but petrographic, chemical, and other data from later analyses are incorporated into this catalog to better characterize individual particles and describe the groups. A large number of particles have no characterization beyond that done by Powell. Complete descriptions of the particles and all known references are provided. The catalog is intended for anyone interested in the rock types collected by Dave Scott and Jim Irwin in the Hadley-Appenine region, and particularly for researchers requiring sample allocations

    Vitamin D, Calcium and Blood Pressure in the U.S.

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    Vitamin D and calcium have received increased attention for their potential roles in improving cardiovascular health. The active form of vitamin D, 1,25-hydroxyvitamin D (25[OH]D), may influence blood pressure by increasing gastrointestinal calcium absorption. The objectives of this study were to first examine the association between blood pressure and blood serum 25(OH)D levels, and then explore the interaction between 25(OH)D, calcium intake, and blood pressure. Cross-sectional analysis featured 24,844 U.S. adults aged 20-80 years from three cycles of the National Health and Examination Survey (NHANES 2001-2006). Linear regression models were used to determine the adjusted association of 25(OH)D categories with blood pressure. An interaction term between 25(OH)D and calcium intake was fitted in the fully adjusted regression model. All analyses accounted for the complex survey design. The mean age was 37.5 (0.3) and 48.6% of participants were male. Mean systolic blood pressure (SBP) and diastolic blood pressure (DBP) in mmHg were 120.3 (0.3) and 69.3 (0.2), respectively. Linear regression models showed that SBP, but not DBP, was negatively and significantly associated with increasing 25(OH)D levels. Moreover, a significant interaction between 25(OH)D and calcium intake levels was noted for DBP (P=0.040). Conclusively, the association between 25(OH)D levels and DBP may differ by calcium intake in the U.S. population

    Volatiles in glasses from the HSDP2 drill core

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    H2O, CO2, S, Cl, and F concentrations are reported for 556 glasses from the submarine section of the 1999 phase of HSDP drilling in Hilo, Hawaii, providing a high-resolution record of magmatic volatiles over ~200 kyr of a Hawaiian volcano's lifetime. Glasses range from undegassed to having lost significant volatiles at near-atmospheric pressure. Nearly all hyaloclastite glasses are degassed, compatible with formation from subaerial lavas that fragmented on entering the ocean and were transported by gravity flows down the volcano flank. Most pillows are undegassed, indicating submarine eruption. The shallowest pillows and most massive lavas are degassed, suggesting formation by subaerial flows that penetrated the shoreline and flowed some distance under water. Some pillow rim glasses have H2O and S contents indicating degassing but elevated CO2 contents that correlate with depth in the core; these tend to be more fractionated and could have formed by mixing of degassed, fractionated magmas with undegassed magmas during magma chamber overturn or by resorption of rising CO2-rich bubbles by degassed magmas. Intrusive glasses are undegassed and have CO2 contents similar to adjacent pillows, indicating intrusion shallow in the volcanic edifice. Cl correlates weakly with H2O and S, suggesting loss during low-pressure degassing, although most samples appear contaminated by seawater-derived components. F behaves as an involatile incompatible element. Fractionation trends were modeled using MELTS. Degassed glasses require fractionation at pH2O ≈ 5–10 bars. Undegassed low-SiO2 glasses require fractionation at pH2O ≈ 50 bars. Undegassed and partially degassed high-SiO2 glasses can be modeled by coupled crystallization and degassing. Eruption depths of undegassed pillows can be calculated from their volatile contents assuming vapor saturation. The amount of subsidence can be determined from the difference between this depth and the sample's depth in the core. Assuming subsidence at 2.5 mm/y, the amount of subsidence suggests ages of ~500 ka for samples from the lower 750 m of the core, consistent with radiometric ages. H2O contents of undegassed low-SiO2 HSDP2 glasses are systematically higher than those of high-SiO2 glasses, and their H2O/K2O and H2O/Ce ratios are higher than typical tholeiitic pillow rim glasses from Hawaiian volcanoes

    Evaluation of the Health Resources and Services Administration (HRSA) Behavioral Health Workforce and Education Training (BHWET) Grant

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    Our poster focuses on expanding the number of MS social work and MEd school counseling graduate students working with persons across the lifespan in vulnerable and medically underserved populations, providing evidence-based behavioral health services. In order to prepare the selected students, Interprofessional Education trainings and a 3-credit IPE academic course were administered, and data gathered and analyzed. The purpose of this research is to evaluate the effectiveness of the trainings and IPE academic courses. For the purpose of the IPE Integrated Care Trainings, pre-post test data were collected. In addition, open-ended questions were added to the post-test to ascertain additional feedback to improve the trainings and assess effectiveness. Pre-post test data were also collected for the 3-credit IPE academic course, in addition to open-ended questions, conducted after the completion of the IPE course to gain feedback. Chi-Square analyses were run for the quantitative data and themes were pulled from the open-ended questions. This presentation will focus on data outcomes from Year 3 of the four-year HRSA grant. In year three, data has been collected and analyzed from two IPE Integrated Care Trainings and two IPE academic courses, thus far. Participants for the trainings include HRSA-stipend students, field/faculty supervisors, and community members. In the first training of Year 3, N= 66. In the second training of Year 3, N= 95. In the two IPE academic courses, N=39. It was hypothesized that student pre/post data values are more likely to be significant, as compared to field/faculty supervisors, which has been proven true

    Evolution education in Canada's museums: where is human evolution?

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    While an interest in the origin of human beings may be a cultural universal, there are various views and beliefs about how this event took place. In Canada, a recent (2010) Angus Reid survey revealed that only 61% of Canadians accepted that humans evolved over millions of years; 39% of the population either believed in creationism or did not accept evolution as a scientific fact. These statistics suggest that human evolution education is a topic that needs to be addressed.This thesis investigates the role of museums in public education about human evolution. Prior to this study, the number of Canadian museums with exhibits about this topic was unknown. Sixteen Canadian museums participated in this study, and the results demonstrated that only two had permanent exhibits on human evolution, and one creationist museum presented a biblically-based account of human origins. Here, it is argued that more of Canada's museums should consider incorporating human evolution education into their mandates.Bien que l'intérêt envers les origines de l'Homme soit un universel culturel, plusieurs points de vue et croyances divergent au sujet du commencement de l'humanité. Au Canada, un récent sondage (2010) de la firme Angus Reid a révélé que seulement 61% des Canadiens acceptent le fait que l'humain ait évolué sur une période de millions d'années, et 39% croient plutôt au créationnisme ou ne considèrent pas l'évolution comme un fait scientifique. Ces statistiques suggèrent que l'évolution de l'homme soit un sujet qui doit être abordé. Cette thèse étudiera le rôle que jouent les musées dans l'éducation de la population à propos de l'évolution de l'homme. Le nombre de musées canadiens présentant une exposition sur le sujet n'était pas encore connu avant la réalisation de cette étude. Selon les résultats de celle-ci, seuls deux des seize musées canadiens qui y ont pris part consacraient une exposition permanente à l'évolution de l'homme, et un autre musée, créationniste, proposait une version biblique des origines de l'homme. Cette thèse démontre que davantage de musées canadiens devraient envisager d'avoir pour objectif l'éducation de la population sur l'évolution humaine

    Biological Evolution in Canadian Science Curricula

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    The social controversy around biological evolution and creationism continues to persist throughout North America (Alters and Nelson 2002; Berkman and Plutzer 2011; Moore and Cotner 2009; Wiles and Alters 2011; Winslow and others 2011; Rissler and others 2014). This fierce debate has been quite visible in the United States, but seems to be relatively muted in Canada, which may lead many to believe that the dispute does not exist north of the border. While this issue has been researched and documented thoroughly in the US, relatively little is known about its dynamics in Canada, despite the powerful presence of such controversies there (Wiles and others 2005)

    Neuroblastoma patient outcomes, tumor differentiation, and ERK activation are correlated with expression levels of the ubiquitin ligase UBE4B.

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    BackgroundUBE4B is an E3/E4 ubiquitin ligase whose gene is located in chromosome 1p36.22. We analyzed the associations of UBE4B gene and protein expression with neuroblastoma patient outcomes and with tumor prognostic features and histology.MethodsWe evaluated the association of UBE4B gene expression with neuroblastoma patient outcomes using the R2 Platform. We screened neuroblastoma tumor samples for UBE4B protein expression using immunohistochemistry. FISH for UBE4B and 1p36 deletion was performed on tumor samples. We then evaluated UBE4B expression for associations with prognostic factors and with levels of phosphorylated ERK in neuroblastoma tumors and cell lines.ResultsLow UBE4B gene expression is associated with poor outcomes in patients with neuroblastoma and with worse outcomes in all patient subgroups. UBE4B protein expression was associated with neuroblastoma tumor differentiation, and decreased UBE4B protein levels were associated with high-risk features. UBE4B protein levels were also associated with levels of phosphorylated ERK.ConclusionsWe have demonstrated associations between UBE4B gene expression and neuroblastoma patient outcomes and prognostic features. Reduced UBE4B protein expression in neuroblastoma tumors was associated with high-risk features, a lack of differentiation, and with ERK activation. These results suggest UBE4B may contribute to the poor prognosis of neuroblastoma tumors with 1p36 deletions and that UBE4B expression may mediate neuroblastoma differentiation

    Antimicrobial activity of extracts from native plants of temperate Australia

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    Introduction: Significant effort has been invested in looking at the antimicrobial activity of plant extracts from tropical regions of Australia, with less interest in those from more temperate environments. We sought to redress this imbalance by examining antimicrobial activities of extracts from native plants of Victoria. Methods: Sixteen plant samples were obtained around the Ballarat region of Victoria. Plant material was desiccated, ground and extracted with methanol at room temperature. Methanol extracts were subsequently dissolved in water, filtered and freeze dried. Extracts were dissolved in water and their activity determined against eight bacterial species. Plant extracts that showed appreciable antibacterial activity in the initial antimicrobial screen were examined further with both their MICs and MBCs determined. Results: Ten of the sixteen plant extracts showed antimicrobial activity. Extracts of Eucalyptus, Melaleuca, Prostanthera and Westringia were particularly active with MICs as low as 0.25 mg/ml against organisms including P. aeruginosa and S. aureus. Conclusion: The current study demonstrates the antimicrobial activity of plant extracts from temperate Australia. These may serve as precursors for future chemotherapy agents

    Optimising cosmic shear surveys to measure modifications to gravity on cosmic scales

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    We consider how upcoming photometric large scale structure surveys can be optimized to measure the properties of dark energy and possible cosmic scale modifications to General Relativity in light of realistic astrophysical and instrumental systematic uncertainities. In particular we include flexible descriptions of intrinsic alignments, galaxy bias and photometric redshift uncertainties in a Fisher Matrix analysis of shear, position and position-shear correlations, including complementary cosmological constraints from the CMB. We study the impact of survey tradeoffs in depth versus breadth, and redshift quality. We parameterise the results in terms of the Dark Energy Task Force figure of merit, and deviations from General Relativity through an analagous Modified Gravity figure of merit. We find that intrinsic alignments weaken the dependence of figure of merit on area and that, for a fixed observing time, a fiducial Stage IV survey plateaus above roughly 10,000deg2 for DE and peaks at about 5,000deg2 as the relative importance of IAs at low redshift penalises wide, shallow surveys. While reducing photometric redshift scatter improves constraining power, the dependence is shallow. The variation in constraining power is stronger once IAs are included and is slightly more pronounced for MG constraints than for DE. The inclusion of intrinsic alignments and galaxy position information reduces the required prior on photometric redshift accuracy by an order of magnitude for both the fiducial Stage III and IV surveys, equivalent to a factor of 100 reduction in the number of spectroscopic galaxies required to calibrate the photometric sample.Comment: 13 pages, 6 figures. Fixed an error in equation 19 which changes the right hand panels of figures 1 and 2, and modifies conclusions on the results for fixed observing tim
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