Ultracold dipolar gases - a challenge for experiments and theory

We present a review of recent results concerning the physics of ultracold trapped dipolar gases. In particular, we discuss the Bose-Einstein condensation for dipolar Bose gases and the BCS transition for dipolar Fermi gases. In both cases we stress the dominant role of the trap geometry in determining the properties of the system. We present also results concerning bosonic dipolar gases in optical lattices and the possibility of obtaining variety of different quantum phases in such case. Finally, we analyze various possible routes towards achieving ultracold dipolar gases.Comment: This paper is based on the lecture given by M. Lewenstein at the Nobel Symposium ''Coherence and Condensation in Quantum Systems'', Gothesburg, 4-7.12.200

Instabilities and the roton spectrum of a quasi-1D Bose-Einstein condensed gas with dipole-dipole interactions

We point out the possibility of having a roton-type excitation spectrum in a quasi-1D Bose-Einstein condensate with dipole-dipole interactions. Normally such a system is quite unstable due to the attractive portion of the dipolar interaction. However, by reversing the sign of the dipolar interaction using either a rotating magnetic field or a laser with circular polarization, a stable cigar-shaped configuration can be achieved whose spectrum contains a `roton' minimum analogous to that found in helium II. Dipolar gases also offer the exciting prospect to tune the depth of this `roton' minimum by directly controlling the interparticle interaction strength. When the minimum touches the zero-energy axis the system is once again unstable, possibly to the formation of a density wave.Comment: 7 pages, 6 figures. Special Issue: "Ultracold Polar Molecules: Formation and Collisions

Rapid in vivo analysis of synthetic promoters for plant pathogen phytosensing

<p>Abstract</p> <p>Background</p> <p>We aimed to engineer transgenic plants for the purpose of early detection of plant pathogen infection, which was accomplished by employing synthetic pathogen inducible promoters fused to reporter genes for altered phenotypes in response to the pathogen infection. Toward this end, a number of synthetic promoters consisting of inducible regulatory elements fused to a red fluorescent protein (RFP) reporter were constructed for use in phytosensing.</p> <p>Results</p> <p>For rapid analysis, an <it>Agrobacterium</it>-mediated transient expression assay was evaluated, then utilized to assess the inducibility of each synthetic promoter construct <it>in vivo</it>. Tobacco (<it>Nicotiana tabacum </it>cv. Xanthi) leaves were infiltrated with <it>Agrobacterium </it>harboring the individual synthetic promoter-reporter constructs. The infiltrated tobacco leaves were re-infiltrated with biotic (bacterial pathogens) or abiotic (plant defense signal molecules salicylic acid, ethylene and methyl jasmonate) agents 24 and 48 hours after initial agroinfiltration, followed by RFP measurements at relevant time points after treatment. These analyses indicated that the synthetic promoter constructs were capable of conferring the inducibility of the RFP reporter in response to appropriate phytohormones and bacterial pathogens, accordingly.</p> <p>Conclusions</p> <p>These observations demonstrate that the <it>Agrobacterium</it>-mediated transient expression is an efficient method for <it>in vivo </it>assays of promoter constructs in less than one week. Our results provide the opportunity to gain further insights into the versatility of the expression system as a potential tool for high-throughput <it>in planta </it>expression screening prior to generating stably transgenic plants for pathogen phytosensing. This system could also be utilized for temporary phytosensing; e.g., not requiring stably transgenic plants.</p

Canagliflozin and Cardiovascular and Renal Outcomes in Type 2 Diabetes Mellitus and Chronic Kidney Disease in Primary and Secondary Cardiovascular Prevention Groups

Background: Canagliflozin reduces the risk of kidney failure in patients with type 2 diabetes mellitus and chronic kidney disease, but effects on specific cardiovascular outcomes are uncertain, as are effects in people without previous cardiovascular disease (primary prevention). Methods: In CREDENCE (Canagliflozin and Renal Events in Diabetes With Established Nephropathy Clinical Evaluation), 4401 participants with type 2 diabetes mellitus and chronic kidney disease were randomly assigned to canagliflozin or placebo on a background of optimized standard of care. Results: Primary prevention participants (n=2181, 49.6%) were younger (61 versus 65 years), were more often female (37% versus 31%), and had shorter duration of diabetes mellitus (15 years versus 16 years) compared with secondary prevention participants (n=2220, 50.4%). Canagliflozin reduced the risk of major cardiovascular events overall (hazard ratio [HR], 0.80 [95% CI, 0.67-0.95]; P=0.01), with consistent reductions in both the primary (HR, 0.68 [95% CI, 0.49-0.94]) and secondary (HR, 0.85 [95% CI, 0.69-1.06]) prevention groups (P for interaction=0.25). Effects were also similar for the components of the composite including cardiovascular death (HR, 0.78 [95% CI, 0.61-1.00]), nonfatal myocardial infarction (HR, 0.81 [95% CI, 0.59-1.10]), and nonfatal stroke (HR, 0.80 [95% CI, 0.56-1.15]). The risk of the primary composite renal outcome and the composite of cardiovascular death or hospitalization for heart failure were also consistently reduced in both the primary and secondary prevention groups (P for interaction &gt;0.5 for each outcome). Conclusions: Canagliflozin significantly reduced major cardiovascular events and kidney failure in patients with type 2 diabetes mellitus and chronic kidney disease, including in participants who did not have previous cardiovascular disease

STATISTICAL PROCESS CONTROL IN THE ASSESSMENT OF DRIP IRRIGATION USING WASTEWATER

The aim of this study was to evaluate drip irrigation as a process, by monitoring the average flow applied by the emitter using tools of statistical quality control. Four kinds of drippers were selected, two inline labyrinth type and two online where one of the inline emitters was not self-compensating and the other, self-compensating emitter. The system was installed in the field and tested for 85 hours, using three kinds of treated domestic sewage effluents and tap water. The system was under statistical control when the emitters were new, however none of the drippers reaches the manufacturer's specification for average flow. The online drippers showed more dispersion for individual flow measurements and the non-self-compensating inline dripper was more accurately for this variable. After the end of experiment, irrigation process was not under statistical control for any kind of emitter. When using treated wastewater effluents for irrigation we recommend a first evaluation before 7 working hours, to implement appropriated correcting procedures to reduce clogging and as a result, maintain the process quality./[]/Coordination for Improvement of Higher Education Personnel (CAPES)/Brasil/[308764]/National Council for Scientific and Technological Development (CNPq)/Brasil/[2003-7]/National Council for Scientific and Technological Development (CNPq)/Brasil/[403519]/National Council for Scientific and Technological Development (CNPq)/Brasil/[2013-6]/National Institute of Science and Technology in Salinity (INCTSal)/BrasilUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Agroalimentarias::Centro de Investigaciones Agronómicas (CIA