953 research outputs found

    Resultados Da Colpofixação Sacroespinal Associada A Colporrafia Anterior Para O Tratamento Do Prolapso De CĂșpula Vaginal

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    To evaluate the results of sacrospinous colpopexy surgery associated with anterior colporrhaphy for the treatment of womeN with post-hysterectomy vaginal vault prolapse. Methods This prospective study included 20women with vault prolapse, PelvicOrgan Prolapse Quantification System (POP-Q) stage ≄ 2, treated between January 2003 and February 2006, and evaluated in a follow-up review (more than one year later). Genital prolapse was evaluated qualitatively in stages and quantitatively in centimeters. Prolapse stage < 2 was considered to be the cure criterion. Statistical analysis was performed using the Wilcoxon test (paired samples) to compare the points and stages of prolapse before and after surgery. Results Evaluation of the vaginal vault after one year revealed that 95% of subjects were in stage zero and that 5% were in stage 1. For cystocele, 50% were in stage 1, 10% were in stage 0 (cured) and 40% were in stage 2. For rectocele, three women were in stage 1 (15%), one was in stage 2 (5%) and 16 had no further prolapse. The most frequent complication was pain in the right buttock, with remission of symptoms in all three cases three months after surgery. Conclusions In this retrospective study, the surgical correction of vault prolapse using a sacrospinous ligament fixation technique associatedwith anterior colporrhaphy proved effective in resolving genital prolapse. Despite the low complication rates, there was a high rate of cystocele, which may be caused by posterior vaginal shifting due to either the technique or an overvaluation by the POP-Q system. © 2016 by Thieme PublicaçÔes Ltda, Rio de Janeiro, Brazil.382778

    Exploratory Path Planning Using the Max-Min Ant System Algorithm

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    In the path planning problem for autonomous mobile robots, robots have to plan their path from the start position to the goal. In this paper, we investigate the application of the MMAS algorithm to the exploratory path planning problem, in which the robots should explore the environment at the same time they plan the path. Max-min ant system is an ant colony optimization algorithm that exploits the best solutions found. In addition, to analyze the quality of solutions obtained, we also analyze the traveled distance spent by robots in the first iteration of the algorithm. The environment is previously unknown to the robots, although it is represented by a topological map, that does not require precise information from the environment and provides a simple way to execute the navigation of the path. Thus, the paths are represented by a sequence of actions that the robots should execute to reach the goal. The navigation of the best solution found was implemented in a realistic robotic simulator. The proposed algorithm provides a very good performance in relation to a genetic algorithm and the well-known A* algorithm that deal with this problem

    Exploratory Path Planning for Mobile Robots in Dynamic Environments with Ant Colony Optimization

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    In the path planning task for autonomous mobile robots, robots should be able to plan their trajectory to leave the start position and reach the goal, safely. There are several path planning approaches for mobile robots in the literature. Ant Colony Optimization algorithms have been investigated for this problem, giving promising results. In this paper, we propose the Max-Min Ant System for Dynamic Path Planning algorithm for the exploratory path planning task for autonomous mobile robots based on topological maps. A topological map is an environment representation whose focus is the main reference points of the environment and their connections. Based on this representation, the path can be composed by a sequence of state/actions pairs, which facilitates the navigability of the path, with no need to have the information of the complete map. The proposed algorithm was evaluated in static and dynamic envi- ronments, showing promising results in both of them. Experiments in dynamic environments show the adaptability of our proposal

    Cirurgia Com Tela Para Correção De Prolapso De Parede Anterior: Metanålise

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    Purpose Pelvic organ prolapse (POP) is a major health issue worldwide, affecting 6–8% of women. The most affected site is the anterior vaginal wall. Multiple procedures and surgical techniques have been used, with or without the use of vaginal meshes, due to common treatment failure, reoperations, and complication rates in some studies. Methods Systematic review of the literature and meta-analysis regarding the use of vaginal mesh in anterior vaginal wall prolapse was performed. A total of 115 papers were retrieved after using the medical subject headings (MESH) terms: ‘anterior pelvic organ prolapse OR cystocele AND surgery AND (mesh or colporrhaphy)’ in the PubMed database. Exclusion criteria were: follow-up shorter than 1 year, use of biological or absorbable meshes, and inclusion of other vaginal wall prolapses. Studies were put in a data chart by two independent editors; results found in at least two studies were grouped for analysis. Results After the review of the titles by two independent editors, 70 studies were discarded, and after abstract assessment, 18 trials were eligible for full text screening. For final screening and meta-analysis, after applying the Jadad score ( > 2), 12 studies were included. Objective cure was greater in the mesh surgery group (odds ratio [OR] = 1,28 [1,07–1,53]), which also had greater blood loss (mean deviation [MD] = 45,98 [9,72–82,25]), longer surgery time (MD = 15,08 [0,48–29,67]), but less prolapse recurrence (OR = 0,22 [01,3–0,38]). Dyspareunia, symptom resolution and reoperation rates were not statistically different between groups. Quality of life (QOL) assessment through the pelvic organ prolapse/urinary incontinence sexual questionnaire (PISQ-12), the pelvic floor distress inventory (PFDI-20), the pelvic floor impact questionnaire (PFIQ-7), and the perceived quality of life scale (PQOL) was not significantly different. Conclusions Anterior vaginal prolapse mesh surgery has greater anatomic cure rates and less recurrence, although there were no differences regarding subjective cure, reoperation rates and quality of life. Furthermore, mesh surgery was associated with longer surgical time and greater blood loss. Mesh use should be individualized, considering prior history and risk factors for recurrence. © 2016 by Thieme PublicaçÔes Ltda, Rio de Janeiro, Brazil.38735636

    Cirurgia com tela para correção de prolapso de parede anterior: metanålise

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    Pelvic organ prolapse (POP) is a major health issue worldwide, affecting 6–8% of women. The most affected site is the anterior vaginal wall. Multiple procedures and surgical techniques have been used, with or without the use of vaginal meshes, due to common treatment failure, reoperations, and complication rates in some studies. Methods Systematic review of the literature and meta-analysis regarding the use of vaginal mesh in anterior vaginal wall prolapse was performed. A total of 115 papers were retrieved after using the medical subject headings (MESH) terms: ‘anterior pelvic organ prolapse OR cystocele AND surgery AND (mesh or colporrhaphy)’ in the PubMed database. Exclusion criteria were: follow-up shorter than 1 year, use of biological or absorbable meshes, and inclusion of other vaginal wall prolapses. Studies were put in a data chart by two independent editors; results found in at least two studies were grouped for analysis. Results After the review of the titles by two independent editors, 70 studies were discarded, and after abstract assessment, 18 trials were eligible for full text screening. For final screening and meta-analysis, after applying the Jadad score ( > 2), 12 studies were included. Objective cure was greater in the mesh surgery group (odds ratio [OR] = 1,28 [1,07–1,53]), which also had greater blood loss (mean deviation [MD] = 45,98 [9,72–82,25]), longer surgery time (MD = 15,08 [0,48–29,67]), but less prolapse recurrence (OR = 0,22 [01,3–0,38]). Dyspareunia, symptom resolution and reoperation rates were not statistically different between groups. Quality of life (QOL) assessment through the pelvic organ prolapse/urinary incontinence sexual questionnaire (PISQ-12), the pelvic floor distress inventory (PFDI-20), the pelvic floor impact questionnaire (PFIQ-7), and the perceived quality of life scale (PQOL) was not significantly different. Conclusions Anterior vaginal prolapse mesh surgery has greater anatomic cure rates and less recurrence, although there were no differences regarding subjective cure, reoperation rates and quality of life. Furthermore, mesh surgery was associated with longer surgical time and greater blood loss. Mesh use should be individualized, considering prior history and risk factors for recurrence.387356364Prolapso de ĂłrgĂŁos pĂ©lvicos Ă© problema de saĂșde pĂșblicas, sendo o mais comum o anterior. Para tratamento sĂŁo utilizadas cirurgias, com ou sem telas. O uso de telas Ă© para diminuir recidivas, mas nĂŁo h ĂĄ consenso. MĂ©todos: Foi realizada revisĂŁo da literatura e metanĂĄlise, sobre uso de telas na correção do prolapso anterior. Base de dados foi PUBMED , com termos (MESH): “Anterior Pelvic Organ OR Cystocele AND Surgery AND (Mesh or Colporrhaphy)”. CritĂ©rios de exclusĂŁo foram: seguimento menor que 1 ano, telas biolĂłgicas ou absorvĂ­veis. Resultados: foram avaliados 115 artigos. ApĂłs revisĂŁo dos tĂ­tulos, 70 estudos foram descartados e 18 apĂłs leitura de resumos. ApĂłs critĂ©rios de Jadad (>2), 12 estudos foram incluĂ­dos. AnĂĄlise estatĂ­stica foi razĂŁo de risco ou diferença entre mĂ©dias dos grupos, e as anĂĄlises com grande heterogeneidade foram avaliadas atravĂ©s de anĂĄlise de efeito aleatĂłrio. Resultados: Cura objetiva foi superior no grupo com tela - OR 1,28 (1,07-1,53, p ≀ 0,00001), maior perda sanguĂ­nea - diferença mĂ©dia (MD) 45,98 (9,72-82,25, p = 0,01), tempo cirĂșrgico mais longo - MD 15,08 (0,48-29,67, p = 0,04), porĂ©m menor recorrĂȘncia - OR 0,22 (0,13-0,38, p = 0,00001), nĂŁo apresentando maior resolução dos sintomas - OR 1,93 (0,83-4,51, p = 0,15). Dispareunia e taxa de reoperação tambĂ©m nĂŁo foram diferentes entre grupos. Qualidade de vida nĂŁo apresentou diferença. ConclusĂ”es: Cirurgia com tela para prolapso vaginal anterior apresenta melhor taxa de cura anatĂŽmica e menor recorrĂȘncia, sem diferenças cura subjetiva, reoperação e qualidade de vida. HĂĄ maior tempo cirĂșrgico e perda sanguĂ­nea. Uso de telas deve ser individualizado

    Domain wall roughening in dipolar films in the presence of disorder

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    We derive a low-energy Hamiltonian for the elastic energy of a N\'eel domain wall in a thin film with in-plane magnetization, where we consider the contribution of the long-range dipolar interaction beyond the quadratic approximation. We show that such a Hamiltonian is analogous to the Hamiltonian of a one-dimensional polaron in an external random potential. We use a replica variational method to compute the roughening exponent of the domain wall for the case of two-dimensional dipolar interactions.Comment: REVTEX, 35 pages, 2 figures. The text suffered minor changes and references 1,2 and 12 were added to conform with the referee's repor

    Violation of self-similarity in the expansion of a 1D Bose gas

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    The expansion of a 1D Bose gas is investigated employing the Lieb-Liniger equation of state within the local density approximation. We show that during the expansion the density profile of the gas does not follow a self-similar solution, as one would expect from a simple scaling Ansatz. We carry out a variational calculation, which recovers the numerical results for the expansion, the equilibrium properties of the density profile, and the frequency of the lowest compressional mode. The variational approach allows for the analysis of the expansion in all interaction regimes between the mean field and the Tonks-Girardeau limits, and in particular shows the range of parameters for which the expansion violates self-similarity.Comment: 6 pages, 5 eps figure

    Raman spectroscopy vs voltammetry: a voltammetric approach to elucidate different chemicals in a range of pharmaceutical tablets.

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    Over the years, Electroanalysis has been widely applied to elucidate redox behavior of novel molecules. The selectivity and low cost are spotlight features in pharmacopeial methods of identification, that can be reached by voltammetric approaches. In this work, differential pulse voltammetric (DPV) profile and the slope of the linear regression obtained from calibration graphs along with the scan study are proposed as new perspective of identification assays. With the proposed methodology we were able to identify the similarities among DPV profile and the slopes obtained for each tablet. In addition, this new technology was successfully employed to identify the following chemicals: Paracetamol (PAR), Promethazine (PMZ), Diclofenac (DIC), Piroxicam (PRX), Indomethacin (IND) and Cyclobenzaprine (CBP) in pharmaceutical assays using Pencil Graphite Electrodes. Furthermore, our new methodology was effectively compared to Raman Spectroscopy for the analysis of the range of chemicals in the pharmaceutical assays
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