Efecto de ácido salicílico, ácido β aminobutírico, periodos de calentamiento e imbibición sobre la germinación de la semilla de palma aceitera (Elaeis guineensis Jacq.) en Ecuador

The commercial production of germinated of African oil palm (Elaeis guineensis Jacq) seeds, it takes 150 days, giving place to the development of infections caused by pathogens. With the aim of reducing the production time of germinated seeds of African oil palm (Elaeis guineensis Jacq.) and preserve their phytosanitary status, four factors were evaluated: three levels of imbibition before taking the seeds to heating, two periods of heating, two levels of imbibition before entering the germination rooms, and two inductors: Salicylic Acid (SA) and β-aminobutyric Acid (BABA) in doses of 1 mM and 2.5 mM respectively. This results in a total of 24 treatments in addition of the control. A total of 30 seeds were evaluated per treatment and per repetition from the same Dura type bunch, with zero days of storage. A completely random design with factorial arrangement +1 was used, assisted by Tukey's test at 5 %. The results showed that the seeds that stayed during the first imbibition for 6 days in water, 2 days in GABA or in AS before entering heating, and with 20 days of heating, presented in 82 days the highest percentage of optimal germination (34.44 % and 23.89 %, respectively). and the treatment that was during the first imbibition 6 days in water and 2 days in GABA, and 20 days of heating, achieved the highest percentage of optimal germination (40 %). The control showed higher incidence of diseases (79 %) with respect to the other factors (16 %).  Study findings could be used to decrease seed germination time and damage caused by pathogens.La producción comercial de semillas germinadas de palma africana (Elaeis guineensis Jacq) tarda 150 días, dando lugar al desarrollo de infecciones causadas por patógenos. Con el objetivo de disminuir el tiempo de producción de semillas germinadas de palma aceitera africana y preservar su estado fitosanitario, se evaluaron cuatro factores: i) tres niveles de imbibición antes de ingresar a calentamiento, ii) dos periodos de calentamiento, iii) dos niveles de imbibición antes de ingresar a cuartos de germinación y iv) dos inductores: ácido salicílico (AS) y ácido β aminobutírico (BABA) en dosis de 1 mM y 2,5 mM, respectivamente; como resultado se obtuvo un total de 24 tratamientos más un testigo. Se evaluaron 30 semillas por tratamiento y por repetición procedentes de un mismo racimo tipo Dura, con cero días de almacenamiento. Se utilizó un diseño completamente al azar con arreglo factorial +1, asistido por la prueba de Tukey al 5 %. Los resultados mostraron que las semillas que estuvieron durante la primera imbibición 6 días en agua y 2 días en BABA o en AS, más 20 días de calentamiento, presentaron en 82 días el mayor porcentaje de germinación óptima (34,44 % y 23,89 %, respectivamente), y el tratamiento que estuvo durante la primera imbibición 6 días en agua y 2 días en BABA, más 20 días de calentamiento, logró el mayor porcentaje de germinación óptima (40 %). El testigo presentó mayor incidencia de enfermedades (79 %) con respecto a los factores (16 %). Los hallazgos del estudio podrían usarse para disminuir el tiempo de germinación de semillas y los daños provocados por patógenos

Nurses' perceptions of aids and obstacles to the provision of optimal end of life care in ICU

Contains fulltext : 172380.pdf (publisher's version ) (Open Access

Risk factors for three-vessel coronary artery disease in patients of Northwest Mexico

Introduction: Three-vessel coronary artery disease is an advanced manifestation of atherosclerosis, with high prevalence in Mexico. Objective: The aim of this study was to describe coronary risk factors in a group of patients with three-vessel coronary artery disease in Northwest Mexico. Methods: A cross sectional study was conducted on a population with three-vessel coronary artery disease from May 2015 to February 2016. The disease was defined when ≥70% stenosis was present in each major epicardial coronary artery. Anthropometric and biochemical parameters were measured in each patient. Ankle-Brachial Index was measured with vascular ultrasound, and Syntax score calculation with an on-line application. Statistical analysis for qualitative differences was performed using Pearson X2 test, with p < 0.05 being considered as significant. Results: The study included 100 patients, of whom 75 were male (mean age 63 ± 9 years) and 25 female (mean age 69 ± 9 years). The coronary risk factors observed were diabetes (58%), hypertension (86%), smoking (68%), dyslipidaemia (100%), metabolic syndrome (71%), and obesity/overweight (75%). Diabetes and metabolic syndrome prevalence was higher in women (p = 0.03), but smoking was higher in men (76%, p = 0.003). Ankle-Brachial Index was abnormal in 58% of patients, the mean Syntax score was in 36.9 ± 11.5, and the prevalence of left main coronary heart disease was 36%. Conclusions: This group of patients with complex coronary lesions has a high prevalence of coronary risk factors, which could represent a worse prognosis. Resumen: Introducción: La enfermedad coronaria de tres vasos (ECTV) es una manifestación avanzada de aterosclerosis, con alta prevalencia en el noroeste de México. Objetivo: Describir los factores de riesgo coronario (FRC) en un grupo de enfermos con ECTV en el noroeste de México. Métodos: De mayo de 2015 a febrero de 2016 se realizó un estudio transversal en una población del noroeste de México diagnosticada con ECTV. Se definió ECTV cuando existía estenosis ≥70% en cada una de las arterias coronarias epicárdicas mayores. Se midieron parámetros antropométricos y bioquímicos en cada paciente. Los parámetros para el índice tobillo-brazo (ITB) se obtuvieron con ultrasonido vascular (Edan SonoTrax 8 Hz) y un cálculo de puntaje Syntax con una aplicación en línea. Análisis estadístico con χ2 de Pearson para diferencias cualitativas Se consideró significativo cuando p ≤ 0.05. Resultados: Se estudiaron 25 mujeres (edad 69 ± 9 años) y 75 varones (edad 63 ± 9 años). Los FRC observados fueron diabetes (58%), hipertensión (86%), antecedente de tabaquismo (68%), dislipidemia (100%), síndrome metabólico (71%) y sobrepeso/obesidad (75%). En las mujeres la prevalencia de diabetes y síndrome metabólico fue mayor que en los varones (p = 0.03), pero el tabaquismo fue más prevalente en los varones (76%, p = 0.003). El ITB se encontró anormal en el 58% de los pacientes, el puntaje Syntax promedio fue de 36.9 ± 11.5 y la prevalencia de la enfermedad del tronco de la arteria coronaria izquierda fue del 36%. Conclusión: En este grupo de estudio con lesiones coronarias complejas existe alta prevalencia de FRC que se refleja en y posiblemente un peor pronóstico. Keywords: Coronary artery disease, Atherosclerosis, Risk factors, Syntax score, Ankle-Brachial Index, Mexico, Palabras clave: Enfermedad arterial coronaria, Aterosclerosis, Factores de riesgo, Puntaje Syntax, Índice tobillo-brazo, Méxic

Compilación de Proyectos de Investigacion de 1984-2002

Instituto Politecnico Nacional. UPIICS

Evolution over Time of Ventilatory Management and Outcome of Patients with Neurologic Disease∗

OBJECTIVES: To describe the changes in ventilator management over time in patients with neurologic disease at ICU admission and to estimate factors associated with 28-day hospital mortality. DESIGN: Secondary analysis of three prospective, observational, multicenter studies. SETTING: Cohort studies conducted in 2004, 2010, and 2016. PATIENTS: Adult patients who received mechanical ventilation for more than 12 hours. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Among the 20,929 patients enrolled, we included 4,152 (20%) mechanically ventilated patients due to different neurologic diseases. Hemorrhagic stroke and brain trauma were the most common pathologies associated with the need for mechanical ventilation. Although volume-cycled ventilation remained the preferred ventilation mode, there was a significant (p &lt; 0.001) increment in the use of pressure support ventilation. The proportion of patients receiving a protective lung ventilation strategy was increased over time: 47% in 2004, 63% in 2010, and 65% in 2016 (p &lt; 0.001), as well as the duration of protective ventilation strategies: 406 days per 1,000 mechanical ventilation days in 2004, 523 days per 1,000 mechanical ventilation days in 2010, and 585 days per 1,000 mechanical ventilation days in 2016 (p &lt; 0.001). There were no differences in the length of stay in the ICU, mortality in the ICU, and mortality in hospital from 2004 to 2016. Independent risk factors for 28-day mortality were age greater than 75 years, Simplified Acute Physiology Score II greater than 50, the occurrence of organ dysfunction within first 48 hours after brain injury, and specific neurologic diseases such as hemorrhagic stroke, ischemic stroke, and brain trauma. CONCLUSIONS: More lung-protective ventilatory strategies have been implemented over years in neurologic patients with no effect on pulmonary complications or on survival. We found several prognostic factors on mortality such as advanced age, the severity of the disease, organ dysfunctions, and the etiology of neurologic disease

International Nosocomial Infection Control Consortium report, data summary of 50 countries for 2010-2015: Device-associated module

•We report INICC device-associated module data of 50 countries from 2010-2015.•We collected prospective data from 861,284 patients in 703 ICUs for 3,506,562 days.•DA-HAI rates and bacterial resistance were higher in the INICC ICUs than in CDC-NHSN's.•Device utilization ratio in the INICC ICUs was similar to CDC-NHSN's. Background: We report the results of International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2010-December 2015 in 703 intensive care units (ICUs) in Latin America, Europe, Eastern Mediterranean, Southeast Asia, and Western Pacific. Methods: During the 6-year study period, using Centers for Disease Control and Prevention National Healthcare Safety Network (CDC-NHSN) definitions for device-associated health care-associated infection (DA-HAI), we collected prospective data from 861,284 patients hospitalized in INICC hospital ICUs for an aggregate of 3,506,562 days. Results: Although device use in INICC ICUs was similar to that reported from CDC-NHSN ICUs, DA-HAI rates were higher in the INICC ICUs: in the INICC medical-surgical ICUs, the pooled rate of central line-associated bloodstream infection, 4.1 per 1,000 central line-days, was nearly 5-fold higher than the 0.8 per 1,000 central line-days reported from comparable US ICUs, the overall rate of ventilator-associated pneumonia was also higher, 13.1 versus 0.9 per 1,000 ventilator-days, as was the rate of catheter-associated urinary tract infection, 5.07 versus 1.7 per 1,000 catheter-days. From blood cultures samples, frequencies of resistance of Pseudomonas isolates to amikacin (29.87% vs 10%) and to imipenem (44.3% vs 26.1%), and of Klebsiella pneumoniae isolates to ceftazidime (73.2% vs 28.8%) and to imipenem (43.27% vs 12.8%) were also higher in the INICC ICUs compared with CDC-NHSN ICUs. Conclusions: Although DA-HAIs in INICC ICU patients continue to be higher than the rates reported in CDC-NSHN ICUs representing the developed world, we have observed a significant trend toward the reduction of DA-HAI rates in INICC ICUs as shown in each international report. It is INICC's main goal to continue facilitating education, training, and basic and cost-effective tools and resources, such as standardized forms and an online platform, to tackle this problem effectively and systematically