2,076 research outputs found

    Implementación de los módulos de venta y almacenamiento de un ERP local en la empresa Contratistas Generales Waras en 2021-2022

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    Universidad Nacional Agraria La Molina. Facultad de Economía y Planificación. Departamento Académico de Gestión EmpresarialEl presente Trabajo de Suficiencia Profesional está redactado siguiendo los lineamientos del reglamento de titulación por trabajo de suficiencia profesional – UNALM emitido mediante resolución N° 0083-2022-CU-UNALM. Aborda la problemática y la solución encontrada mediante la implementación de un ERP local en la empresa Contratistas Generales Waras, la cual se dedica a la venta de comidas y bebidas en la ciudad de Huaraz hace más de once años, con una facturación mensual promedio de 170 mil soles. La autora se unió a la empresa en marzo de 2021, cuando el mundo estaba saliendo de los impactos causados por la pandemia del Covid-19, y su tarea fue liderar la implementación del ERP local, con una situación inicial en la que tanto las ventas como el control de inventarios se manejaban de manera manual, careciendo de cualquier tipo de registro trazable. Además, no existía una interacción efectiva entre los departamentos de ventas y almacén. Ante las proyecciones de mermas realizadas y considerando los beneficios derivados de la implementación de un sistema ERP, se optó por seleccionar un proveedor local que se ajustara al presupuesto y abordara las necesidades de la empresa. Siguiendo la metodología ASAP, se procedió a implementar el ERP, proceso que tomó un período total de seis meses a partir de la aprobación del proyecto. Como resultado de esta iniciativa, se logró una drástica reducción del 600% en las horas-hombre previamente requeridas para la realización de inventarios. De manera similar, se registró una disminución del 538.3% en las pérdidas monetarias debidas a mermas de productos y a los cierres de caja al término de los turnos. Adicionalmente, se observó un incremento en la rotación de los productos. En resumen, al finalizar el proyecto se logró integrar las ventas con el inventario de manera exitosa gracias a la implementación de un ERP.The present Professional Proficiency Work is drafted following the guidelines of the degree by professional proficiency work regulations - UNALM issued by resolution No. 0083- 2022-CU-UNALM. It addresses the problem and the solution found through the implementation of a local ERP in the company Contratistas Generales Waras, which has been engaged in the sale of food and beverages in the city of Huaraz for over eleven years, with an average monthly revenue of 170,000 soles. The author joined the company in March 2021, when the world was recovering from the impacts caused by the Covid-19 pandemic, and her task was to lead the implementation of the local ERP, in an initial situation where both sales and inventory control were managed manually, lacking any traceable record. Furthermore, there was no effective interaction between the sales and warehouse departments. Based on the projected losses and considering the benefits derived from the implementation of an ERP system, the decision was made to select a local provider that fit within the budget and addressed the company's needs. Following the ASAP methodology, the ERP was implemented, a process that took a total period of six months from project approval. As a result of this initiative, a drastic reduction of 600% in man-hours previously required for inventory management was achieved. Similarly, there was a decrease of 538.3% in monetary losses due to product shrinkage and end-of-shift cash closures. Additionally, an increase in product turnover was observed. In summary, at the end of the project, successful integration of sales with inventory was achieved thanks to the implementation of an ERP

    Data Augmentation for Speaker Identification under Stress Conditions to Combat Gender-Based Violence

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    This article belongs to the Special Issue IberSPEECH 2018: Speech and Language Technologies for Iberian LanguagesA Speaker Identification system for a personalized wearable device to combat gender-based violence is presented in this paper. Speaker recognition systems exhibit a decrease in performance when the user is under emotional or stress conditions, thus the objective of this paper is to measure the effects of stress in speech to ultimately try to mitigate their consequences on a speaker identification task, by using data augmentation techniques specifically tailored for this purpose given the lack of data resources for this condition. An extensive experimentation has been carried out for assessing the effectiveness of the proposed techniques. First, we conclude that the best performance is always obtained when naturally stressed samples are included in the training set, and second, when these are not available, their substitution and augmentation with synthetically generated stress-like samples improves the performance of the system.This work is partially supported by the Spanish Government-MinECo project TEC2017-84395-P and Madrid Regional Project Y2018/TCS-5046

    Soft Skills: A Comparative Analysis Between Online and Classroom Teaching

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    Currently the Spanish universities are making a great effort to effectively incorporate the development and assessment of generic skills in their training programs. Information and communications technologies (ICT) offer a wide range of possibilities but create uncertainty among teachers about the process and results. It is considered of interest to conduct a study to analyze the extent to which social skills like commitment, communication and teamwork are acquired by students and teachers. It seeks to ascertain the influence of the learning context, online or classroom training, in the development of these personal skills among the participants in the sample. For this study two universities have been chosen, Universidad a Distancia de Madrid (UDIMA) offering online training environment, and Universidad Politécnica de Madrid (UPM) with classroom training modality. A total of 257 individuals, 230 students and 27 teachers have answered the survey called Evalsoft. This instrument was designed in the project with the same name by a research team from Universidad Complutense of Madrid (UCM). Some interesting conclusions can be highlighted: it is in the online context where there are higher levels of commitment and teamwork than in the classroom modality; teachers have higher social skills that students and these improve with age. Sex and the training program appear to influence these social skills

    Immature rats show ovulatory defects similar to those in adult rats lacking prostaglandin and progesterone actions

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    Gonadotropin-primed immature rats (GPIR) constitute a widely used model for the study of ovulation. Although the equivalence between the ovulatory process in immature and adult rats is generally assumed, the morphological and functional characteristics of ovulation in immature rats have been scarcely considered. We describe herein the morphological aspects of the ovulatory process in GPIR and their response to classical ovulation inhibitors, such as the inhibitor of prostaglandin (PG) synthesis indomethacin (INDO) and a progesterone (P) receptor (PR) antagonist (RU486). Immature Wistar rats were primed with equine chorionic gonadotropin (eCG) at 21, 23 or 25 days of age, injected with human chorionic gonadotropin (hCG) 48 h later, and sacrificed 16 h after hCG treatment, to assess follicle rupture and ovulation. Surprisingly, GPIR showed age-related ovulatory defects close similar to those in adult rats lacking P and PG actions. Rats primed with eCG at 21 or 23 days of age showed abnormally ruptured corpora lutea in which the cumulus-oocyte complex (COC) was trapped or had been released to the ovarian interstitum, invading the ovarian stroma and blood and lymphatic vessels. Supplementation of immature rats with exogenous P and/or PG of the E series did not significantly inhibit abnormal follicle rupture. Otherwise, ovulatory defects were practically absent in rats primed with eCG at 25 days of age. GPIR treated with INDO showed the same ovulatory alterations than vehicle-treated ones, although affecting to a higher proportion of follicles. Blocking P actions with RU486 increased the number of COC trapped inside corpora lutea and decreased ovulation. The presence of ovulatory defects in GPIR, suggests that the capacity of the immature ovary to undergo the coordinate changes leading to effective ovulation is not fully established in Wistar rats primed with eCG before 25 days of age

    This is My Baby Interview: an adaptation to the spanish language and culture

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    INTRODUCTION: Evaluating the emotional state of the parents is important for determining the intervention in the context of a family with a baby with Down syndrome. "This is my baby" is an interview that measures the acceptance, commitment and awareness of influence of parents towards their baby. The Spanish adaptation of this instrument helps to better understand the emotional state of parents of children with developmental disorders. PATIENTS AND METHODS: This is a transcultural adaptation and determination of the reliability, sensitivity to change, and internal consistency of the “This Is My Baby” interview. A cross-cultural adaptation and reliability analysis was carried out. A total of 32 families of babies with Down syndrome participated in this multicenter study. RESULTS: The values obtained for the intraclass correlation coefficient (ICC) indicated a good level of concordance with a significative level of p < 0.001, and the values of the standard error of measurement (SEM) and of the minimum detectable change (MDC) were reduced. The weighted Kappa coefficient showed values that were moderate to excellent. CONCLUSION: The results suggest that the Spanish version of the This Is My Baby interview is a reliable instrument to measure the levels of acceptance, commitment, and awareness of influence of parents of an infant with Down syndrome.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

    Plasma Rich in Growth Factors (PRGF) in Transepithelial Photorefractive Keratectomy (TPRK)

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    To evaluate the usage of plasma rich in growth factor (PRGF) in transepithelial photorefractive keratectomy (TPRK) in low and moderate myopia, patients who underwent myopic and astigmatism TPRK with PRGF were involved in this retrospective, observational study. Subjects underwent a surgical procedure between February 2019 and June 2019. A three-month follow-up was recorded. Pain score was assessed with a visual analogue scale (0–10) and re-epithelialization time recorded. A total of 48 eyes from 24 patients were recruited. Mean uncorrected distance visual acuity (UDVA) was 20/20.31 (0.00 ± 0.02 LogMAR). A total of 98% of eyes did not change corrected distance visual acuity (CDVA) lines. Two percent of eyes lost one line of CDVA. Preoperative spherical equivalent was −2.67 ± 1.37 D and after three months changed to −0.21 ± 0.34 D, and 2% of eyes changed 0.50 D or more between one and three months. Pain score was 3.29 ± 0.61 (3 to 6) score points at day one and 0.08 ± 0.27 score points at day seven. Finally, re-epithelialization time was 2.50 ± 1.20 days. PRGF addition to conventional refractive treatment such as TPRK seems to alleviate immediate postoperative pain and positively contribute to corneal re-epithelization time.publishersversionPeer reviewe

    What have we learned from the surveys of the AEC, AECP and the Observatory of Infection in Surgery? Compliance with postoperative infection prevention measures and comparison with the AEC recommendations

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    Antibiotic prophylaxis; Surgical site infection; Surveys and questionnairesProfilaxi antibiòtica; Infecció del lloc quirúrgic; Enquestes i qüestionarisProfilaxis antibiótica; Infección del sitio quirúrgico; Encuestas y cuestionariosBefore planning improvement strategies, it is crucial to know the degree of implementation of preventative measures for postoperative infection. The aggregated results of 3 surveys carried out by the Observatory of Infection in Surgery to members of 11 associations of surgeons and perioperative nurses are presented. The questions were aimed to determine the knowledge of the scientific evidence, personal beliefs and the actual use of the main measures. Of 2295 respondents, 45.1% did not receive feedback on the infection rate of their unit. Insufficient knowledge of some of the main prevention recommendations and some disturbing rates of use were observed. The preferred strategies to improve compliance with preventive guidelines and their degree of implementation were investigated. A gap between scientific evidence and clinical practice in the prevention of infection in different surgical specialties was confirmed

    Urinary cyclophilin A as marker of tubular cell death and kidney injury

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    Background: Despite the term acute kidney injury (AKI), clinical biomarkers for AKI re-flect function rather than injury and independent markers of injury are needed. Tubular cell death, including necroptotic cell death, is a key feature of AKI. Cyclophilin A (CypA) is an intracellular protein that has been reported to be released during necroptosis. We have now explored CypA as a potential marker for kidney injury in cultured tubular cells and in clinical settings of ischemia-reperfusion injury (IRI), characterized by limitations of current diagnostic criteria for AKI. Meth-ods: CypA was analyzed in cultured human and murine proximal tubular epithelial cells exposed to chemical hypoxia, hypoxia/reoxygenation (H/R) or other cell death (apoptosis, necroptosis, fer-roptosis) inducers. Urinary levels of CypA (uCypA) were analyzed in patients after nephron sparing surgery (NSS) in which the contralateral kidney is not disturbed and kidney grafts with initial function. Results: Intracellular CypA remained unchanged while supernatant CypA increased in parallel to cell death induction. uCypA levels were higher in NSS patients with renal artery clamping (that is, with NSS-IRI) than in no clamping (NSS-no IRI), and in kidney transplantation (KT) recipients (KT-IRI) even in the presence of preserved or improving kidney function, while this was not the case for urinary Neutrophil gelatinase-associated lipocalin (NGAL). Furthermore, higher uCypA levels in NSS patients were associated with longer surgery duration and the incidence of AKI increased from 10% when using serum creatinine (sCr) or urinary output criteria to 36% when using high uCypA levels in NNS clamping patients. Conclusions: CypA is released by kidney tubular cells during different forms of cell death, and uCypA increased during IRI-induced clinical kidney injury independently from kidney function parameters. Thus, uCypA is a potential bi-omarker of kidney injury, which is independent from decreased kidney functionResearch by the authors was funded by FIS/ FEDER funds (PI17/00257, PI18/01386, PI19/00588, PI19/00815, DTS18/00032, ERA-PerMed-JTC2018 (KIDNEY ATTACK AC18/00064 and PERSTIGAN AC18/00071, ISCIII-RETIC REDinREN RD016/0009), Sociedad Española de Nefrología, FRIAT, Comunidad de Madrid en Biomedicina B2017/BMD-3686 CIFRA2-CM. Salary support: ISCIII Miguel Servet to A.B.S., MICIN Ramon y Cajal to M.D.S.-N., REDinREN RD016/0009 to M.F.-B.,SENEFRO to D.M.-S. and Consejería de Educación, Juventud y Deporte (Comunidad de Madrid/FSE) to A.M.L.-
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