Polarization conversion on nanostructured metallic surfaces fabricated by LIPSS

Conference on Laser-Based Micro-and Nanoprocessing (LBMP) at Photonics West Conference (13ª. 2019. San Francisco, California). ISBN: 978-1-5106-2455-9 © 2019 SPIE. This work is part of the following projects: ECOGRAB, funded by the Government of Spain under the RETOS COLABORACIÓN I+D+i programme. LASER4SURF has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 768636.Waveplates modify polarization by generating a phase change. Laser Induced Periodic Surface Structures (LIPSS) have recently started to be studied as waveplates due to the birefringence in-duced by the nanoripples, easily fabricated in a one-step process by laser, where LIPSS morphology is defined by the characteristics of the laser process parameters and the substrate material. The optical properties of these waveplates are defined by LIPSS parameters such as period, depth or width of the ripples. In this work we have deposited thin film coatings on stainless steel samples containing LIPSS for different coating thickness and composition. Results show that thin film coatings are a good candidate for the tunability of LIPSS birefringence since the coating modifies the induced polarization change and reflectivity of the sample depending on coating thickness and composition, as expected from numerical simulations.Depto. de ÓpticaFac. de Ciencias FísicasTRUEUnión Europea. H2020Ministerio de Ciencia e Innovación (MICINN)pu

LIPSS manufacturing with regularity control through laser wavefront curvature

Laser-Induced Periodic Surface Structures (LIPSS) manufacturing is a convenient laser direct-writing technique for the fabrication of nanostructures with adaptable characteristics on the surface of virtually any material. In this paper, we study the influence of 1D laser wavefront curvature on nanoripples spatial regularity, by irradiating stainless steel with a line-focused ultrafast laser beam emitting 120 fs pulses at a wavelength of 800 nm and with 1 kHz repetition rate. We find high correlation between the spatial regularity of the fabricated nanostructures and the wavefront characteristics of the laser beam, with higher regularity being found with quasi-plane-wave illumination. Our results provide insight regarding the control of LIPSS regularity, which is essential for industrial applications involving the LIPSS generation technique

Femtosecond laser fabrication of LIPSS-based waveplates on metallic surfaces

A fast and reliable method for the fabrication of polarization modifying devices using femtosecond laser is reported. A setup based on line focusing is used for the generation of LIPSS on stainless steel, processing at different speeds between 0.8 and 2.4 mm/s with constant energy per pulse of 1.4 mJ. SEM and AFM characterizations of the LIPSS show a progressive increase in period as the processing speed increases, while height remains approximately constant in the studied range. Optical characterization of the devices shows an induced change in the polarization of the reflected beam that varies with the processing speed, which allows a controlled fabrication of these devices

Femtosecond laser fabrication of LIPSS-based waveplates on metallic surfaces

A fast and reliable method for the fabrication of polarization modifying devices using femtosecond laser is reported. A setup based on line focusing is used for the generation of LIPSS on stainless steel, processing at different speeds between 0.8 and 2.4 mm/s with constant energy per pulse of 1.4 mJ. SEM and AFM characterizations of the LIPSS show a progressive increase in period as the processing speed increases, while height remains approximately constant in the studied range. Optical characterization of the devices shows an induced change in the polarization of the reflected beam that varies with the processing speed, which allows a controlled fabrication of these devices

The comparative responsiveness of Hospital Universitario Princesa Index and other composite indices for assessing rheumatoid arthritis activity

Objective To evaluate the responsiveness in terms of correlation of the Hospital Universitario La Princesa Index (HUPI) comparatively to the traditional composite indices used to assess disease activity in rheumatoid arthritis (RA), and to compare the performance of HUPI-based response criteria with that of the EULAR response criteria. Methods Secondary data analysis from the following studies: ACT-RAY (clinical trial), PROAR (early RA cohort) and EMECAR (pre-biologic era long term RA cohort). Responsiveness was evaluated by: 1) comparing change from baseline (Delta) of HUPI with Delta in other scores by calculating correlation coefficients; 2) calculating standardised effect sizes. The accuracy of response by HUPI and by EULAR criteria was analyzed using linear regressions in which the dependent variable was change in global assessment by physician (Delta GDA-Phy). Results Delta HUPI correlation with change in all other indices ranged from 0.387 to 0.791); HUPI's standardized effect size was larger than those from the other indices in each database used. In ACT-RAY, depending on visit, between 65 and 80% of patients were equally classified by HUPI and EULAR response criteria. However, HUPI criteria were slightly more stringent, with higher percentage of patients classified as non-responder, especially at early visits. HUPI response criteria showed a slightly higher accuracy than EULAR response criteria when using Delta GDA-Phy as gold standard. Conclusion HUPI shows good responsiveness in terms of correlation in each studied scenario (clinical trial, early RA cohort, and established RA cohort). Response criteria by HUPI seem more stringent than EULAR''s

CIBERER : Spanish national network for research on rare diseases: A highly productive collaborative initiative

Altres ajuts: Instituto de Salud Carlos III (ISCIII); Ministerio de Ciencia e Innovación.CIBER (Center for Biomedical Network Research; Centro de Investigación Biomédica En Red) is a public national consortium created in 2006 under the umbrella of the Spanish National Institute of Health Carlos III (ISCIII). This innovative research structure comprises 11 different specific areas dedicated to the main public health priorities in the National Health System. CIBERER, the thematic area of CIBER focused on rare diseases (RDs) currently consists of 75 research groups belonging to universities, research centers, and hospitals of the entire country. CIBERER's mission is to be a center prioritizing and favoring collaboration and cooperation between biomedical and clinical research groups, with special emphasis on the aspects of genetic, molecular, biochemical, and cellular research of RDs. This research is the basis for providing new tools for the diagnosis and therapy of low-prevalence diseases, in line with the International Rare Diseases Research Consortium (IRDiRC) objectives, thus favoring translational research between the scientific environment of the laboratory and the clinical setting of health centers. In this article, we intend to review CIBERER's 15-year journey and summarize the main results obtained in terms of internationalization, scientific production, contributions toward the discovery of new therapies and novel genes associated to diseases, cooperation with patients' associations and many other topics related to RD research

LIPSS manufacturing with regularity control through laser wavefront curvature

Laser-Induced Periodic Surface Structures (LIPSS) manufacturing is a convenient laser direct-writing technique for the fabrication of nanostructures with adaptable characteristics on the surface of virtually any material. In this paper, we study the influence of 1D laser wavefront curvature on nanoripples spatial regularity, by irradiating stainless steel with a line-focused ultrafast laser beam emitting 120 fs pulses at a wavelength of 800 nm and with 1 kHz repetition rate. We find high correlation between the spatial regularity of the fabricated nanostructures and the wavefront characteristics of the laser beam, with higher regularity being found with quasi-plane-wave illumination. Our results provide insight regarding the control of LIPSS regularity, which is essential for industrial applications involving the LIPSS generation technique

Femtosecond laser fabrication of LIPSS-based waveplates on metallic surfaces

A fast and reliable method for the fabrication of polarization modifying devices using femtosecond laser is reported. A setup based on line focusing is used for the generation of LIPSS on stainless steel, processing at different speeds between 0.8 and 2.4 mm/s with constant energy per pulse of 1.4 mJ. SEM and AFM characterizations of the LIPSS show a progressive increase in period as the processing speed increases, while height remains approximately constant in the studied range. Optical characterization of the devices shows an induced change in the polarization of the reflected beam that varies with the processing speed, which allows a controlled fabrication of these devices