Environmental Justice at School: Understanding Research, Policy, and Practice to Improve Our Children's Health

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/91105/1/j.1746-1561.2012.00694.x.pd

Vulnerability anti-patterns:a timeless way to capture poor software practices (Vulnerabilities)

There is a distinct communication gap between the software engineering and cybersecurity communities when it comes to addressing reoccurring security problems, known as vulnerabilities. Many vulnerabilities are caused by software errors that are created by software developers. Insecure software development practices are common due to a variety of factors, which include inefficiencies within existing knowledge transfer mechanisms based on vulnerability databases (VDBs), software developers perceiving security as an afterthought, and lack of consideration of security as part of the software development lifecycle (SDLC). The resulting communication gap also prevents developers and security experts from successfully sharing essential security knowledge. The cybersecurity community makes their expert knowledge available in forms including vulnerability databases such as CAPEC and CWE, and pattern catalogues such as Security Patterns, Attack Patterns, and Software Fault Patterns. However, these sources are not effective at providing software developers with an understanding of how malicious hackers can exploit vulnerabilities in the software systems they create. As developers are familiar with pattern-based approaches, this paper proposes the use of Vulnerability Anti-Patterns (VAP) to transfer usable vulnerability knowledge to developers, bridging the communication gap between security experts and software developers. The primary contribution of this paper is twofold: (1) it proposes a new pattern template – Vulnerability Anti-Pattern – that uses anti-patterns rather than patterns to capture and communicate knowledge of existing vulnerabilities, and (2) it proposes a catalogue of Vulnerability Anti-Patterns (VAP) based on the most commonly occurring vulnerabilities that software developers can use to learn how malicious hackers can exploit errors in software

Freight Transport and Health: A Comprehensive Investigation of Planning and Public Participation within U.S. Host Communities.

Transportation-related air and noise pollution from heavy-duty freight engines is associated with respiratory and cardiovascular illnesses, cancer, diabetes, nervous system and cognitive effects, hospital admissions, sleep disruption, and premature mortality. Research is needed to understand how residents in host communities nearby freight gateways (e.g., ports, borders) experience and counter these impacts. With an environmental justice framework, I used: 1) spatial analyses to quantitatively describe the demographic composition of U.S. freight host communities, and 2) institutional ethnography to qualitatively investigate public participation in freight land use deliberations. Quantitatively, I derived demographic descriptions of host communities by overlaying American Community Survey (2005-2009) tract-level data with buffered digitized images of freight gateways. At the 50 largest U.S. freight gateways, results from areally weighted analyses show that populations within 500 meters of a freight gateway have significantly higher proportions of persons of color, Hispanic ethnicity, without a high school diploma, and below the federal poverty level. Logistic regression models also compare 500-meter and 1-mile host communities to non-host communities, and overall results suggest that communities of color are disproportionately compromised by both transportation and industrial air pollution sources. Qualitatively, I synthesized data from interviews, content analysis, and participant observations at two distinct case sites: the proposed New International Trade Crossing in Detroit, Michigan and the Port of Long Beach in Long Beach, California. Interviewees identify catalysts, barriers, and opportunities for addressing freight’s local impacts through institutionally- and community-led strategies. Macroeconomic forces often override local concerns, whereby freight-related development decisions are made in advance or outside of public participation opportunities. Still, host communities may shift deliberations by exposing overlooked risks, legally challenging assessment procedures, proposing site or project alternatives, advocating adoption of sustainable technologies, equalizing mitigation opportunities, or codifying innovative governance structures. This study defines freight transport as an environmental justice issue. Results from quantitative analyses demonstrate patterns of exposure to well-documented freight-related health risks with implications for health equity. Qualitative inquiry enables deconstruction of theories and practices related to public participation and environmental assessment in freight host communities. Collectively, these findings inform cross-sector interventions to address global freight transport’s local threats to public health.PHDHealth Behavior & Health EducationUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/99894/1/nsampson_1.pd

PAGE4 Positivity Is Associated with Attenuated AR Signaling and Predicts Patient Survival in Hormone-Naive Prostate Cancer

Aberrant activation of the androgen receptor (AR) plays a key role during prostate cancer (PCa) development and progression to castration-resistant prostate cancer (CR-PCa) after androgen deprivation therapy, the mainstay systemic treatment for PCa. New strategies to abrogate AR activity and biomarkers that predict aggressive tumor behavior are essential for improved therapeutic intervention. PCa tissue microarrays herein reveal that prostate-associated gene 4 (PAGE4), an X-linked cancer/testis antigen, is highly up-regulated in the epithelium of preneoplastic lesions compared with benign epithelium, but subsequently decreases with tumor progression. We show that AR signaling is attenuated in PAGE4-expressing cells both in vitro and in vivo, most likely via impaired androgen-induced AR nuclear translocation and subsequently reduced AR protein stabilization and phosphorylation at serines 81 and 213. Consistently, epithelial PAGE4 protein levels inversely correlated with AR activation status in hormone-naive and CR-PCa clinical specimens. Moreover, PAGE4 impaired the development of CR-PCa xenografts, and strong PAGE4 immunoreactivity independently predicted favorable patient survival in hormone-naive PCa. Collectively, these data suggest that dysregulation of epithelial PAGE4 modulates AR signaling, thereby promoting progression to advanced lethal PCa and highlight the potential value of PAGE4 as a prognostic and therapeutic target

Strategies to reduce the harmful effects of extreme heat events: A four-city study

Extreme heat events (EHEs) are becoming more intense, more frequent and longer lasting in the 21st century. These events can disproportionately impact the health of low-income, minority, and urban populations. To better understand heat-related intervention strategies used by four U.S. cities, we conducted 73 semi-structured interviews with government and non-governmental organization leaders representing public health, general social services, emergency management, meteorology, and the environmental planning sectors in Detroit, MI; New York City, NY; Philadelphia, PA and Phoenix, AZ—cities selected for their diverse demographics, climates, and climate adaptation strategies. We identified activities these leaders used to reduce the harmful effects of heat for residents in their city, as well as the obstacles they faced and the approaches they used to evaluate these efforts. Local leaders provided a description of how local context (e.g., climate, governance and city structure) impacted heat preparedness. Despite the differences among study cities, political will and resource access were critical to driving heat-health related programming. Upon completion of our interviews, we convened leaders in each city to discuss these findings and their ongoing efforts through day-long workshops. Our findings and the recommendations that emerged from these workshops could inform other local or national efforts towards preventing heat-related morbidity and mortality

Strategies to Reduce the Harmful Effects of Extreme Heat Events: A Four-City Study

Extreme heat events (EHEs) are becoming more intense, more frequent and longer lasting in the 21st century. These events can disproportionately impact the health of low-income, minority, and urban populations. To better understand heat-related intervention strategies used by four U.S. cities, we conducted 73 semi-structured interviews with government and non-governmental organization leaders representing public health, general social services, emergency management, meteorology, and the environmental planning sectors in Detroit, MI; New York City, NY; Philadelphia, PA and Phoenix, AZ—cities selected for their diverse demographics, climates, and climate adaptation strategies. We identified activities these leaders used to reduce the harmful effects of heat for residents in their city, as well as the obstacles they faced and the approaches they used to evaluate these efforts. Local leaders provided a description of how local context (e.g., climate, governance and city structure) impacted heat preparedness. Despite the differences among study cities, political will and resource access were critical to driving heat-health related programming. Upon completion of our interviews, we convened leaders in each city to discuss these findings and their ongoing efforts through day-long workshops. Our findings and the recommendations that emerged from these workshops could inform other local or national efforts towards preventing heat-related morbidity and mortality

Increased population exposure to Amphan‐scale cyclones under future climates

International audienceAbstract Southern Asia experiences some of the most damaging climate events in the world, with loss of life from some cyclones in the hundreds of thousands. Despite this, research on climate extremes in the region is substantially lacking compared to other parts of the world. To understand the narrative of how an extreme event in the region may change in the future, we consider Super Cyclone Amphan, which made landfall in May 2020, bringing storm surges of 2–4 m to coastlines of India and Bangladesh. Using the latest CMIP6 climate model projections, coupled with storm surge, hydrological, and socio‐economic models, we consider how the population exposure to a storm surge of Amphan's scale changes in the future. We vary future sea level rise and population changes consistent with projections out to 2100, but keep other factors constant. Both India and Bangladesh will be negatively impacted, with India showing >200% increased exposure to extreme storm surge flooding (>3 m) under a high emissions scenario and Bangladesh showing an increase in exposure of >80% for low‐level flooding (>0.1 m). It is only when we follow a low‐emission scenario, consistent with the 2°C Paris Agreement Goal, that we see no real change in Bangladesh's storm surge exposure, mainly due to the population and climate signals cancelling each other out. For India, even with this low‐emission scenario, increases in flood exposure are still substantial (>50%). While here we attribute only the storm surge flooding component of the event to climate change, we highlight that tropical cyclones are multifaceted, and damages are often an integration of physical and social components. We recommend that future climate risk assessments explicitly account for potential compounding factors