The Role of Nutritional Status in Neuroepigenetic Modification

Abstract The study of epigenetic has brought about a deeper understanding of developmental programming through a complex network of modifications involving the DNA. While the DNA sequence remains conservative throughout, the mechanism of epigenetic modification involves changes through histone modification, DNA methylation, and chromatin remodeling. The overall dynamic effect of epigenetic modification allows the gene expression to be altered leading to a diverse phenotypical expression; a functional change in the genome without affecting the DNA. The emergence of nutritional neuroepigenetic serves to bring into focus the impact of nutrition as an environmental agent in regulating gene expression patterns leading to phenotypical expression with profound neurological and cognitive implication in later life. This link is supported by evidence from animal models suggesting that epigenetic marks, which are formed following DNA methylation or histone modification, can induce changes leading to developmental diseases or persist into adulthood. The difficulty in understanding the intrinsic biomolecular correlation between 1) epigenetic modification, 2) nutritional imbalance, and 3) cognitive impairment in an animal based model provides a compelling question regarding the developmental origins of cognitive related diseases. There have been few animal model studies involving the molecular basis of neuroepigenetic dysfunction in the relation to overnutrition or under nutrition. The main criteria in this review will focus on the few animal based studies in nutrition based epigenetic reprogramming and its role in neuroepigenetic dysregulation and cognitive impairment

Hoy! Gising!: A study on demand articulation through the use of media

This study determined the demographic profile and socio-economic-characteristics of people who articulate demands through the television program Hoy! Gising! . It also classified the types of problems received by the said program. In addition, this study looked into the exposure of information and motivation of the complainants.The research design of this study is descriptive in nature because it attempted to gain insights on the complainants and the types of problems they bring to H.G. . In accomplishing this task, survey method using semi-structured questions was used in data gathering.The sample size set was one-hundred (100) respondents over a span of three (3) weeks. Only walk-in respondents were taken into consideration in the study. The researchers interviewed the respondents while they were waiting in line at the H.G. office over at the ABS-CBN compound in Quezon City

The optimization of thermoelectric generator array for harnessing electrical power from air conditioning unit

We live in a world where innovations and development are in process and a significant amount of energy is in demand with the consumption of energy, it is also wasted and should be kept minimized by any means. Wasted energy such as heat is found to be a good source of alternative energy. Heat is abundant and oftentimes generated by electrical equipment. The energy harnessed can be stored and utilized using proper power management, thus minimizing waste and conserving energy. The project not only aims on the utilization of harnessed energy for power but also to establish a system that will not depend mainly on electrical energy provided by an electrical source but rather use electrical energy converted from wasted heat energy and save electrical cost. TEG or Thermoelectric is a unique type of transducer that is capable of converting any heat source directly into electrical energy by using the concept of Seebeck Effect. The configuration created for harnessing the waste heat from the air conditioning unit focuses on utilizing the Seebeck Effect by means of installing a cooling system to the cold side of the TEG array, and a copper plate on the hot side of the TEG array to spread the heat evenly on the hot side of the TEG array to attain the highest voltage possible. The electrical output attained will be fed to a DC-DC boost converter boost the voltage to power up certain devices or charge a battery

Design of optimal thermoelectric generator array for harnessing electrical power from air-conditioning unit

A thermoelectric generator array or TEG array was designed and tested that is capable of capturing waste heat energy and convert it into a usable electrical energy that can be used to power up electronic devices requiring low power consumption. An air conditioning unit was used as a source of waste heat energy. A cooling system was designed together with copper plate system that will eventually differentiate the cold side and the hot side of the compressor, which is the source of most of the waste heat. A DC to DC boost converter was also considered to improve the voltage and power being harnessed by the system. Lastly, a voltage monitoring unit was added to continuously monitor the output voltage of the TEG array. The converted electrical energy from waste heat energy is used and tested to check if the harnessed power is able to power up smartphone chargers and similar electronic devices. Experiment results show that the efficiency of the TEG I around 7.1768% and can be improved to 55.2889% efficiency if used together with the DC to DC boost converter. © 2019 Authors