Regional International Courts in Search of Relevance: Adjudicating Politically Sensitive Disputes in Central America and the Caribbean

The Central American and the Caribbean Courts of Justice (CACJ and CCJ) are hybrid judicial institutions. While their Member States envisioned them as EU-style regional economic courts, they have explored the whole extension of their formally delegated functions and have developed peculiar expertise in matters relating to freedom of movement, human and fundamental rights, and other politically fraught issues. The article explains how two International Courts (ICs) seemingly established to build common markets have come to adjudicate high-stakes political disputes, which, ostensibly, have little to do with regional economic integration. The article posits that the scholarship on delegation to ICs is only partially able to provide an answer to this question. It, hence, suggests an alternative theoretical framework by relying on transnational field theory and reflexive sociology. The article demonstrates that, despite the rhetoric of their founding documents, both the CACJ and the CCJ were only partially established to pursue regional economic integration. Instead, both Courts were fashioned at the crossroads of several—and at times even conflicting-forms of legality, power battles, professional interests, and visions of the world that shaped the Central American and Caribbean legal fields over time. Seen through the diachronic lens of the interests, ideologies, professional practices, and visions of the world of the actors inhabiting the Central American and Caribbean legal fields, the involvement of the two Courts in politically sensitive issues becomes less surprising, and-the article argues-it constitutes part of a strategy of the judges to legitimize the two Courts vis-à-vis their peculiar institutional, political, and social environments

The World\u27s Most Powerful International Court? The Centrual American Court of Justice and the Quest for De Facto Authority (1907-2020)

The original Central American Court of Justice (CACJ) is often referenced as the world’s first international court (IC). Functioning from 1907 to 1918, and commonly known as the Cartago Court, this court was the first-ever IC and a precursor to the Permanent Court of Justice, or “World Court”, established in 1922 in The Hague. The CACJ does, however, hold another record. The current incarnation of the court – established in 1994, in Managua, Nicaragua as the judicial arm of the Central American System of Economic Integration (Sistema de la Integración Centroamericana (SICA) – which is the world’s most powerful international court, formally speaking. The 1991 Protocol of Tegucigalpa (the Protocol)and the 1992 Statute of the CACJ (the Statute)6 provide the Court with remarkably extensive powers. The CACJ is competent to rule as an inter-state IC, as a European Union (E.U.)-style regional economic court, as a supranational constitutional court, and as an arbitral tribunal. Access to the Court is also broad and, in fact, broader than that of the Court of Justice of the European Union (C.J.E.U.) and similar regional economic ICs. In addition to states, individuals, national judges, and other private entities have standing before the Court, making it par excellence a “new style” IC; that is to say, an IC with compulsory jurisdiction and access for non-state actors to initiate litigation

Accidental Politicians: How Randomly Selected Legislators Can Improve Parliament Efficiency

We study a prototypical model of a Parliament with two Parties or two Political Coalitions and we show how the introduction of a variable percentage of randomly selected independent legislators can increase the global efficiency of a Legislature, in terms of both the number of laws passed and the average social welfare obtained. We also analytically find an "efficiency golden rule" which allows to fix the optimal number of legislators to be selected at random after that regular elections have established the relative proportion of the two Parties or Coalitions. These results are in line with both the ancient Greek democratic system and the recent discovery that the adoption of random strategies can improve the efficiency of hierarchical organizations.Comment: 19 pages, 7 figures, new improved and longer versio

Quadrato Motor Training (QMT) is associated with DNA methylation changes at DNA repeats: A pilot study

The control of non-coding repeated DNA by DNA methylation plays an important role in genomic stability, contributing to health and healthy aging. Mind-body practices can elicit psychophysical wellbeing via epigenetic mechanisms, including DNA methylation. However, in this context the effects of movement meditations have rarely been examined. Consequently, the current study investigates the effects of a specifically structured movement meditation, called the Quadrato Motor Training (QMT) on psychophysical wellbeing and on the methylation level of repeated sequences. An 8-week daily QMT program was administered to healthy women aged 40-60 years and compared with a passive control group matched for gender and age. Psychological well-being was assessed within both groups by using self-reporting scales, including the Meaning in Life Questionnaire [MLQ] and Psychological Wellbeing Scale [PWB]). DNA methylation profiles of repeated sequences (ribosomal DNA, LINE-1 and Alu) were determined in saliva samples by deep-sequencing. In contrast to controls, the QMT group exhibited increased Search for Meaning, decreased Presence of Meaning and increased Positive Relations, suggesting that QMT may lessen the automatic patterns of thinking. In the QMT group, we also found site-specific significant methylation variations in ribosomal DNA and LINE-1 repeats, consistent with increased genome stability. Finally, the correlations found between changes in methylation and psychometric indices (MLQ and PWB) suggest that the observed epigenetic and psychological changes are interrelated. Collectively, the current results indicate that QMT may improve psychophysical health trajectories by influencing the DNA methylation of specific repetitive sequences

The MASSIMO system for the safeguarding of historic buildings in a seismic area: operationally-oriented platforms

In this paper, the non-invasive system MASSIMO is presented for the monitoring and the seismic vulnerability mitigation of the cultural heritage. It integrates ground-based, airborne and space-borne remote sensing tools with geophysical and in situ surveys to provide the multi-spatial (regional, urban and building scales) and multi-temporal (long-term, short-term, near-real-time and real-time scales) monitoring of test areas and buildings. The measurements are integrated through web-based GIS and 3D visual platforms to support decision-making stakeholders involved in urban planning and structural requalification. An application of this system is presented over the Calabria region for the town of Cosenza and a test historical complex

The Monitoring of Urban Environments and Built-Up Structures in a Seismic Area: Web-Based GIS Mapping and 3D Visualization Tools for the Assessment of the Urban Resources

In this paper, a non-invasive infrastructural system called MASSIMO is presented for the monitoring and the seismic vulnerability mitigation of cultural heritages. It integrates ground-based, airborne and space-borne remote sensing tools with geophysical and in situ surveys to provide a multi-spatial (regional, urban and building scales) and multi-temporal (longterm, short-term and near-real-time scales) monitoring of test areas and buildings. The measurements are integrated through web-based Geographic Information System (GIS) and 3-dimensional visual platforms to support decision-making stakeholders involved in urban and structural requalification planning. An application of this system is presented over the Calabria region for the town of Cosenza and a test historical complex.The present work is supported and funded by the Italian Ministry of Education, University and Research (MIUR) under the research project PON01-02710 "MASSIMO" - "Monitoraggio in Area Sismica di SIstemi MOnumentali".Published9-134T. Sismologia, geofisica e geologia per l'ingegneria sismicaN/A or not JC

Concomitant treatment of brain metastasis with Whole Brain Radiotherapy [WBRT] and Temozolomide [TMZ] is active and improves Quality of Life

BACKGROUND: Brain metastases (BM) represent one of the most frequent complications related to cancer, and their treatment continues to evolve. We have evaluated the activity, toxicity and the impact on Quality of Life (QoL) of a concomitant treatment with whole brain radiotherapy (WBRT) and Temozolomide (TMZ) in patients with brain metastases from solid tumors in a prospective Simon two stage study. METHODS: Fifty-nine patients were enrolled and received 30 Gy WBRT with concomitant TMZ (75 mg/m2/day) for ten days, and subsequently TMZ (150 mg/m2/day) for up to six cycles. The primary end points were clinical symptoms and radiologic response. RESULTS: Five patients had a complete response, 21 patients had a partial response, while 18 patients had stable disease. The overall response rate (45%) exceeded the target activity per study design. The median time to progression was 9 months. Median overall survival was 13 months. The most frequent toxicities included grade 3 neutropenia (15%) and anemia (13%), and only one patient developed a grade 4 thrombocytopenia. Age, Karnofsky performance status, presence of extracranial metastases and the recursive partitioning analysis (RPA) were found to be predictive factors for response in patients. Overall survival (OS) and progression-free survival (PFS) were dependent on age and on the RPA class. CONCLUSION: We conclude that this treatment is well tolerated, with an encouraging objective response rate, and a significant improvement in quality of life (p < 0.0001) demonstrated by FACT-G analysis. All patients answered the questionnaires and described themselves as 'independent' and able to act on their own initiatives. Our study found a high level of satisfaction for QoL, this provides useful information to share with patients in discussions regarding chemotherapy treatment of these lesions