Local magnetism of isolated Mo atoms at substitutional and interstitial sites in Yb metal : Experiment and Theory

Using TDPAD experiment and local spin density calculations, we have observed large 4d moments on isolated Mo atoms at substitutional and octahedral interstitial lattice sites in Yb metal, showing Curie-Weiss local susceptibility and Korringa like spin relaxation rate. As a surprising feature, despite strong hybridization with the Yb neighbours, interstitial Mo atoms show high moment stability with small Kondo temperature. While, magnetism of Mo, at substitutional site is consistent with Kondo type antiferromagnetic d-sp exchange interaction, we suggest that moment stability at the interstitial site is strongly influenced by ferromagnetic polarization of Yb-4f5d band electrons.Comment: 4 pages, 4 figure

Lumbar Scoliosis Analysis Using Deep Learning Based Technique

Medical image interpretation automation saves physicians time and boosts diagnostic confidence. Most medical imaging diagnosis is done manually or semi-automatically. These methods vary when performed by several physicians. This thesis includes mid- sagittal lumbar spine magnetic resonance imaging (MRI) images with labeling and spinal metrics. Two pieces were marked. Professional radiologists created pixel-wise masks to detect vertebral bodies (VBs) in each picture, which a panel of spine surgeons subsequently examined. An enhanced method (VBSeg) compares the segmentation work of traditional and deep-learning architectural techniques. A novel computerized spinal misalignment evaluation method may help spine surgeons make objective decisions about critical surgeries. Angular deviation classifies spondylolisthesis 89% accurately, whereas the area inside the enclosed lumbar curve zone classifies LL adequacy/inadequacy 93%   accurately

Toxicological studies on Helicoverpa armigera in pigeonpea growing in Vidarbha region of Maharashtra, India

Insecticide resistance level in pigeonpea pod borer, Helicoverpa armigera (Hubner) to technical grade insecticides collected from major pigeonpea growing districts of Vidarbha viz., Akola, Amravati, Buldhana, Yavatmal and Washim was worked out. LDP indicated LD50 of Cypermethrin in the range of 1.402 to 9.209 ppm with maximum in Yavatmal (9.209 ppm); LD90 within range of 6.021 to 18.427 ppm. LD50 of Quinalphos in the range of 1.303 to 4.789 ppm with maximum in Yavatmal (4.789 ppm); LD90 within range of 3.150 to 14.194 ppm.LD50 of Methomyl in the range of 1.297 to 3.792 ppm with maximum in Yavatmal (3.792 ppm); LD90 within range of 4.993 to 16.737 ppm.LD50 of Indoxacarb in the range of 0.521 to 2.709 ppm with maximum in Yavatmal (2.709 ppm); LD90 within range of 2.819 to 20.947 ppm.LD50 of Spinosad in the range of 0.713 to 2.408 ppm with maximum in Buldhana (2.408 ppm); LD90 within range of 6.413 to 18.349 ppm. The resistance level is visibly high in cypermethrin, moderate to indoxacarb, quinalphos, spinosad and low to methomyl; Yavatmal and Washim strains expressed higher resistance level to cypermethrin, quinalphos and methomyl, whereas Yavatmal and Buldhana strains expressed higher resistance level to indoxacarb and spinosad. The investigation will help to track resistence level in Helicoverpa armigera to different groups of insecticides

Spin-gap behaviour in the 2-leg spin-ladder BiCu2PO6

We present magnetic suscceptibility and heat capacity data on a new S=1/2 two-leg spin ladder compound BiCu2PO6. From our susceptibility analysis, we find that the leg coupling J1/k_B is ~ 80 K and the ratio of the rung to leg coupling J2/J1 ~ 0.9. We present the magnetic contribution to the heat capacity of a two-leg ladder. The spin-gap Delta/k_B =3 4 K obtained from the heat capacity agrees very well with that obtained from the magnetic susceptibility. Significant inter-ladder coupling is suggested from the susceptibility analysis. The hopping integrals determined using Nth order muffin tin orbital (NMTO) based downfolding method lead to ratios of various exchange couplings in agreement with our experimental data. Based on our band structure analysis, we find the inter-ladder coupling in the bc-plane J2 to be about 0.75J1 placing the compound presumably close to the quantum critical limit.Comment: 8 pages, 5 figure

Sigmoid volvulus in pregnancy: a rare case

Sigmoid volvulus in pregnancy is an extremely uncommon condition, with only 84 cases to have been reported in the English literature. Sigmoid volvulus is the most common cause of bowel obstruction complicating pregnancy, accounting for up to 44 per cent of cases. Overall bowel obstruction in pregnancy varies from 1 in 1500 to 1 in 66,431 deliveries. Intestinal obstruction in pregnancy can be caused by many factors including congenital or postoperative adhesions, volvulus, intussusceptions, hernia and appendicitis, history of intestinal tuberculosis. Patient presented with acute onset abdominal distension associated with multiple episodes of vomiting. When history and clinical examination was suggestive of acute abdomen, diagnosis was confirmed with imaging modalities like abdominal ultrasound, CT (Computerized tomography) scan. Sigmoid volvulus is a surgical emergency and is to be treated promptly. Here we presented a case report on sigmoid volvulus in third trimester pregnancy which was managed by emergency exploration

Pregnancy in rudimentary horn of unicornuate uterus: a rare case

Congenital malformations of the female genital tract result from embryological maldevelopment of Mullerian or paramesonephric ducts. Mullerian duct anomalies (MDAs) are due to agenesis, defective fusion or resorption during embryological development. Unicornuate uterus results due to defective lateral fusion of Mullerian duct. This report discussed a case of pregnancy in rudimentary horn of unicornuate uterus which resulted in rupture of the horn. A patient 35 year old G2A1 with spontaneous conception with 4 months pregnancy came to emergency room with complaints of pain in abdomen and giddiness. On examination her general condition was moderate with pulse rate of 128 bpm, blood pressure of 90/60 mmHg, pallor was present. On per abdomen examination guarding, rigidity and diffuse tenderness was present. On per vaginum examination, uterus size could not be appreciated. Her haemoglobin level was 6 gm%. Ultrasonography of abdomen showed presence of unicornuate uterus with ruptured right horn with fetus in the abdominal cavity and presence of hemoperitoneum. Immediate resuscitative measures were performed, blood transfusion was started and simultaneously patient was shifted to operation theatre for exploratory laparotomy. Intraoperatively hemoperitoneum with unicornuate uterus with non communicating ruptured accessory horn on right side was present and foetus in peritoneal cavity was seen. Ruptured horn was excised and uterus was repaired. The accessory horn and foetus were sent for histopathology examination which was suggestive of placenta increta with gestational hypertrophy and hyperplasia of myometrium with normal tube and ovary. Patient tolerated the procedure well

Epitope recognition by diverse antibodies suggests conformational convergence in an antibody response

Crystal structures of distinct mAbs that recognize a common epitope of a peptide Ag have been determined and analyzed in the unbound and bound forms. These Abs display dissimilar binding site structures in the absence of the Ag. The dissimilarity is primarily expressed in the conformations of complementarity-determining region H3, which is responsible for defining the epitope specificity. Interestingly, however, the three Abs exhibit similar complementarity-determining region conformations in the Ag binding site while recognizing the common epitope, indicating that different pathways of binding are used for Ag recognition. The epitope also exhibits conformational similarity when bound to each of these Abs, although the peptide Ag was otherwise flexible. The observed conformational convergence in the epitope and the Ag binding site was facilitated by the plasticity in the nature of interactions

European Paediatric Formulation Initiative workshop report: Improving the administration of oral liquid medicines in paediatrics using dosing syringes and enteral accessories

Accurate dosing of the right medicine to the right patient is a key element of safe and efficacious pharmacotherapy, yet prone to technical challenges and human error when dosing involves the administration of small volumes of liquid medicines. For this reason, the topic has gained increased attention over the last decade from multiple stakeholder parties e.g. academia, hospital pharmacy, the medical device and pharmaceutical industry, and regulatory agencies. It is now well acknowledged that spoons and cups are not suitable for the measurement of small volumes of oral liquid medicines and that syringes are a better alternative, but syringes for parenteral use should not be used for oral dosing in order to avoid accidental parenteral delivery of oral products. However, dosing accuracy of very small volumes of liquid medicines to young children, and especially pre-term neonates, is still not sufficiently ensured. A workshop was organised in 2018 by the European Paediatric Formulation Initiative to reflect on current status and challenges (first part) and possible strategies to improve the present situation (second part). A voting system (n = 24) was used to consider the most favourable solutions. The harmonisation and/or standardisation of the technical design of oral syringes (including e.g. female/male connection) was considered a key priority

An augmented space recursion study of the electronic structure of rough epitaxial overlayers

In this communication we propose the use of the Augmented Space Recursion as an ideal methodology for the study of electronic and magnetic structures of rough surfaces, interfaces and overlayers. The method can take into account roughness, short-ranged clustering effects, surface dilatation and interdiffusion. We illustrate our method by an application of Fe overlayer on Ag (100) surface.Comment: 22 pages, Latex, 6 postscript figure

Virus shapes and buckling transitions in spherical shells

We show that the icosahedral packings of protein capsomeres proposed by Caspar and Klug for spherical viruses become unstable to faceting for sufficiently large virus size, in analogy with the buckling instability of disclinations in two-dimensional crystals. Our model, based on the nonlinear physics of thin elastic shells, produces excellent one parameter fits in real space to the full three-dimensional shape of large spherical viruses. The faceted shape depends only on the dimensionless Foppl-von Karman number \gamma=YR^2/\kappa, where Y is the two-dimensional Young's modulus of the protein shell, \kappa is its bending rigidity and R is the mean virus radius. The shape can be parameterized more quantitatively in terms of a spherical harmonic expansion. We also investigate elastic shell theory for extremely large \gamma, 10^3 < \gamma < 10^8, and find results applicable to icosahedral shapes of large vesicles studied with freeze fracture and electron microscopy.Comment: 11 pages, 12 figure