10,831 research outputs found
Dynamical behavior of a complex fluid near an out-of-equilibrium transition: approaching simple rheological chaos
We report here an extensive study of sustained oscillations of the viscosity
of a complex fluid near an out-of-equilibrium transition. Using well defined
protocols, we perform rheological measurements of the onion texture near a
layering transition in a Couette flow. This complex fluid exhibits sustained
oscillations of the viscosity, on a large time scale (500s) at controlled
stress. These oscillations are directly correlated to an oscillating
microstrutural change of the texture of the fluid. We observe a great diversity
of dynamical behavior and we show that there is a coupling with spatial effects
in the gradient v direction. This is in agreement with a carefull analysis of
the temporal series of the viscosity with the dynamical system theory. This
analysis indicates that the observed dynamical responses do not strictly
correspond to 3-dimensional chaotic states, probably because some
spatio-temporal effects are present and are likely to play an important role.Comment: submitted to Phys. Rev.
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Evaluation of the Specialist Community Public Health Nursing Peripatetic Assessment Model
The Health Visitor Implementation Plan 2011-15: a call to action, called for an additional 4200 health visitors to be trained by 2015. To accommodate larger numbers of students, specialist community public health nursing (SCPHN) programmes across the UK have undergone significant transformation in terms of practice supervision. Somerset Partnership NHS Trust introduced a peripatetic assessment model involving practice teachers and practice mentors. This differed from traditional one-to-one approaches of supervision to one-to-three. Practice teachers mostly supervised students through close collaboration with mentors who worked directly with students on a daily basis. Using a mixed methods approach, the evaluation aimed to assess the effectiveness of the new model from the perspective of SCPHN students, mentors, practice teachers (PTs) and managers. Data was collected through an anonymous online survey and individual interviews or focus groups. Overall, participants were positive about the peripatetic model’s impact on student learning and practice experience, in addition to the general up-skilling of the wider health visiting workforce and possible implications of continuation into the future. Any concerns raised focused on adequate preparation and support for mentors and the need for clear communication and role differentiation between practice teachers and mentors
Semi-geostrophic particle motion and exponentially accurate normal forms
We give an exponentially-accurate normal form for a Lagrangian particle
moving in a rotating shallow-water system in the semi-geostrophic limit, which
describes the motion in the region of an exponentially-accurate slow manifold
(a region of phase space for which dynamics on the fast scale are exponentially
small in the Rossby number). The result extends to numerical solutions of this
problem via backward error analysis, and extends to the Hamiltonian
Particle-Mesh (HPM) method for the shallow-water equations where the result
shows that HPM stays close to balance for exponentially-long times in the
semi-geostrophic limit. We show how this result is related to the variational
asymptotics approach of [Oliver, 2005]; the difference being that on the
Hamiltonian side it is possible to obtain strong bounds on the growth of fast
motion away from (but near to) the slow manifold
The ontology of causal process theories
There is a widespread belief that the so-called process theories of causation developed by Wesley Salmon and Phil Dowe have given us an original account of what causation really is. In this paper, I show that this is a misconception. The notion of "causal process" does not offer us a new ontological account of causation. I make this argument by explicating the implicit ontological commitments in Salmon and Dowe's theories. From this, it is clear that Salmon's Mark Transmission Theory collapses to a counterfactual theory of causation, while the Conserved Quantity Theory collapses to David Fair's phsyicalist reduction of causation
The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells.
Thymocytes must bind major histocompatibility complex (MHC) proteins on thymic epithelial cells in order to mature into either CD8+ cytotoxic T cells or CD4+ helper T cells. Thymic precursors express both CD8 and CD4, and it has been suggested that the intracellular signals generated by CD8 or CD4 binding to class I or II MHC, respectively, might influence the fate of uncommitted cells. Here we test the notion that intracellular signaling by CD4 directs the development of thymocytes to a CD4 lineage. A hybrid protein consisting of the CD8 extracellular and transmembrane domains and the cytoplasmic domain of CD4 (CD884) should bind class I MHC but deliver a CD4 intracellular signal. We find that expression of a hybrid CD884 protein in thymocytes of transgenic mice leads to the development of large numbers of class I MHC-specific, CD4 lineage T cells. We discuss these results in terms of current models for CD4 and CD8 lineage commitment
3D printing dimensional calibration shape: Clebsch Cubic
3D printing and other layer manufacturing processes are challenged by
dimensional accuracy. Several techniques are used to validate and calibrate
dimensional accuracy through the complete building envelope. The validation
process involves the growing and measuring of a shape with known parameters.
The measured result is compared with the intended digital model. Processes with
the risk of deformation after time or post processing may find this technique
beneficial. We propose to use objects from algebraic geometry as test shapes. A
cubic surface is given as the zero set of a 3rd degree polynomial with 3
variables. A class of cubics in real 3D space contains exactly 27 real lines.
We provide a library for the computer algebra system Singular which, from 6
given points in the plane, constructs a cubic and the lines on it. A surface
shape derived from a cubic offers simplicity to the dimensional comparison
process, in that the straight lines and many other features can be analytically
determined and easily measured using non-digital equipment. For example, the
surface contains so-called Eckardt points, in each of which three of the lines
intersect, and also other intersection points of pairs of lines. Distances
between these intersection points can easily be measured, since the points are
connected by straight lines. At all intersection points of lines, angles can be
verified. Hence, many features distributed over the build volume are known
analytically, and can be used for the validation process. Due to the thin shape
geometry the material required to produce an algebraic surface is minimal. This
paper is the first in a series that proposes the process chain to first define
a cubic with a configuration of lines in a given print volume and then to
develop the point cloud for the final manufacturing. Simple measuring
techniques are recommended.Comment: 8 pages, 1 figure, 1 tabl
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