Resultados maternos perinatales en gestantes con dengue complicado ingresadas en la unidad de cuidados intensivos en el Hospital Escuela Bertha Calderón Roque en el periodo enero 2019 enero 2021

Se realizó un estudio observacional, descriptivo, prospectivo, serie de casos, de corte longitudinal en el Hospital Escuela Bertha Calderón Roque, durante el periodo enero 2019-enero 2021, donde se incluyeron 15 pacientes, el objetivo fue valorar los resultados maternos perinatales de Dengue complicado en gestantes ingresadas en sala de Cuidados Intensivos, durante este período.Se encontró que la edad promedio de las pacientes estudiadas fue de 20 años, todas de áreaurbana y mayor afectación en el I Y II trimestre de gestación. El abordaje diagnóstico para las pacientes con dengue fue clínico y confirmatorio con Serologia IgM dengue apartir del quinto dia de inicio de los sintomas. En este estudio la clasificación clínica del dengue se basa meramente en dengues con signos de alarma y dengue grave con criterios de ingreso unidad de cuidados intensivos los cuales representan 66.7% y 33.3% respectivamente.Entre los signos de alarma sobresale el aumento progresivo del hematocrito donde doce(80%) de las quince pacientes presentaban este dato, asociado a esto trombocitopenia lo queen la mayoría de los ingresos representa el motivo de ingreso a unidad de cuidados intensivospor el alto riesgo de hemorragia. El dolor abdominal es el segundo signo de alarma con másfrecuencia reportado en este estudio nueve pacientes (60%), Acumulación clínica de líquidosdonde dos pacientes (13.3%) presentaron derrame pleural y dos pacientes (13.3%) engrosamiento de la pared vesicular > 4.2 mm, a tres pacientes se les encontró Serositis secundaria (20 %) consecuencia de incremento de la permeabilidad capilar. Se encontraron cinco pacientes con dengue grave (33.3%) basándose en datos clínicos de choque inicial (Hipotensión) entre estos colapso de la vena cava < 30% sugerente a shock por dengue, se encontraron dos pacientes con dengue grave y compromiso grave de órganos como disfunción hepática 13.3%, no se encontró pacientes con sangrado grav

Conocimientos, actitudes y practicas acerca de medidas cadioprotectoras (MCP) en docentes de la universidad de las regiones autonomas de la Costa Caribe Nicaragüense (URACCAN), Bilwi, Region Autonoma del Atlantico Norte (RAAN), Julio-Septiembre de 2014

En este estudio se determinaron los Conocimientos, actitudes y practicas sobre las medidas Cardioprotectoras en docentes no relacionados con medicina de la Universidad de las Regiones Autónomas de la Costa Caribe Nicaragüense (URACCAN). Se identificó la sede principal, en RAAN-Bilwi. Se realizó un estudio observacional de tipo descriptivo de corte transversal, para lo cual se tomó un universo de 40 docentes y una muestra de 30, se diseñó un instrumento validada por informantes claves los cuales eran conocedores de las MCP. Los docentes que aceptaron participar en el estudio recibieron un cuestionario estructurado que fueron llenados de forma anónima. Solamente el 66.6% de los entrevistados había escuchado alguna vez sobre Medidas Cardioprotectoras, siendo la televisión donde la mayoría (60%) recibió información referente a cardioprotección. Gran parte de los entrevistados tienen conocimientos y practicas principalmente Regulares, sin embargo las actitudes que tienen estos son favorables, por lo tanto reconocen los beneficios de la cardioprotección y las consecuencias de las enfermedades cardiovasculares, pero no son puestas en práctica en su totalidad. Es pertinente promover actividades aeróbicas dentro del Recinto Universitario, tomando en cuenta que el nivel de conocimiento sobre MCP en estos docentes es regular, por lo tanto surge la necesidad de darles a conocer los resultados de este estudio a fin de hacer conciencia sobre la prevención de enfermedades cardiovasculares y evitar complicaciones futura

Anales del III Congreso Internacional de Vivienda y Ciudad "Debate en torno a la nueva agenda urbana"

Acta de congresoEl III Congreso Internacional de Vivienda y Ciudad “Debates en torno a la NUEVa Agenda Urbana”, ha sido una apuesta de alto compromiso por acercar los debates centrales y urgentes que tensionan el pleno ejercicio del derecho a la ciudad. Para ello las instituciones organizadoras (INVIHAB –Instituto de Investigación de Vivienda y Hábitat y MGyDH-Maestría en Gestión y Desarrollo Habitacional-1), hemos convidado un espacio que se concretó con potencia en un debate transdisciplinario. Convocó a intelectuales de prestigio internacional, investigadores, académicos y gestores estatales, y en una metodología de innovación articuló las voces académicas con las de las organizaciones sociales y/o barriales en el Foro de las Organizaciones Sociales que tuvo su espacio propio para dar voz a quienes están trabajando en los desafíos para garantizar los derechos a la vivienda y los bienes urbanos en nuestras ciudades del Siglo XXI

La energía del litio en Argentina y Bolivia: comunidad, extractivismo y posdesarrollo

This study analyzes the current relationship between the extraction of lithium, communitarian conflict and development policies in Argentina and Brazil and compares what is happening in one country with what is happening in the other. It is based on the premise that the interaction of the technology-industry-politics triangle is key to an understanding of the modes of development in our peripheral region. The main hypothesis is that an extractive logic predominates in Argentina, while there is a different approach to lithium in Bolivia, due to a wager on a stronger linkage between national actors and the endogenous growth of a productive network, although the results are still uncertain. The study draws on secondary sources, first-hand documentation and interviews in both countries

The DUNE Far Detector Vertical Drift Technology, Technical Design Report

International audienceDUNE is an international experiment dedicated to addressing some of the questions at the forefront of particle physics and astrophysics, including the mystifying preponderance of matter over antimatter in the early universe. The dual-site experiment will employ an intense neutrino beam focused on a near and a far detector as it aims to determine the neutrino mass hierarchy and to make high-precision measurements of the PMNS matrix parameters, including the CP-violating phase. It will also stand ready to observe supernova neutrino bursts, and seeks to observe nucleon decay as a signature of a grand unified theory underlying the standard model. The DUNE far detector implements liquid argon time-projection chamber (LArTPC) technology, and combines the many tens-of-kiloton fiducial mass necessary for rare event searches with the sub-centimeter spatial resolution required to image those events with high precision. The addition of a photon detection system enhances physics capabilities for all DUNE physics drivers and opens prospects for further physics explorations. Given its size, the far detector will be implemented as a set of modules, with LArTPC designs that differ from one another as newer technologies arise. In the vertical drift LArTPC design, a horizontal cathode bisects the detector, creating two stacked drift volumes in which ionization charges drift towards anodes at either the top or bottom. The anodes are composed of perforated PCB layers with conductive strips, enabling reconstruction in 3D. Light-trap-style photon detection modules are placed both on the cryostat's side walls and on the central cathode where they are optically powered. This Technical Design Report describes in detail the technical implementations of each subsystem of this LArTPC that, together with the other far detector modules and the near detector, will enable DUNE to achieve its physics goals

The DUNE Far Detector Vertical Drift Technology, Technical Design Report

International audienceDUNE is an international experiment dedicated to addressing some of the questions at the forefront of particle physics and astrophysics, including the mystifying preponderance of matter over antimatter in the early universe. The dual-site experiment will employ an intense neutrino beam focused on a near and a far detector as it aims to determine the neutrino mass hierarchy and to make high-precision measurements of the PMNS matrix parameters, including the CP-violating phase. It will also stand ready to observe supernova neutrino bursts, and seeks to observe nucleon decay as a signature of a grand unified theory underlying the standard model. The DUNE far detector implements liquid argon time-projection chamber (LArTPC) technology, and combines the many tens-of-kiloton fiducial mass necessary for rare event searches with the sub-centimeter spatial resolution required to image those events with high precision. The addition of a photon detection system enhances physics capabilities for all DUNE physics drivers and opens prospects for further physics explorations. Given its size, the far detector will be implemented as a set of modules, with LArTPC designs that differ from one another as newer technologies arise. In the vertical drift LArTPC design, a horizontal cathode bisects the detector, creating two stacked drift volumes in which ionization charges drift towards anodes at either the top or bottom. The anodes are composed of perforated PCB layers with conductive strips, enabling reconstruction in 3D. Light-trap-style photon detection modules are placed both on the cryostat's side walls and on the central cathode where they are optically powered. This Technical Design Report describes in detail the technical implementations of each subsystem of this LArTPC that, together with the other far detector modules and the near detector, will enable DUNE to achieve its physics goals

Antimicrobial Lessons From a Large Observational Cohort on Intra-abdominal Infections in Intensive Care Units

evere intra-abdominal infection commonly requires intensive care. Mortality is high and is mainly determined by disease-specific characteristics, i.e. setting of infection onset, anatomical barrier disruption, and severity of disease expression. Recent observations revealed that antimicrobial resistance appears equally common in community-acquired and late-onset hospital-acquired infection. This challenges basic principles in anti-infective therapy guidelines, including the paradigm that pathogens involved in community-acquired infection are covered by standard empiric antimicrobial regimens, and second, the concept of nosocomial acquisition as the main driver for resistance involvement. In this study, we report on resistance profiles of Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Enterococcus faecalis and Enterococcus faecium in distinct European geographic regions based on an observational cohort study on intra-abdominal infections in intensive care unit (ICU) patients. Resistance against aminopenicillins, fluoroquinolones, and third-generation cephalosporins in E. coli, K. pneumoniae and P. aeruginosa is problematic, as is carbapenem-resistance in the latter pathogen. For E. coli and K. pneumoniae, resistance is mainly an issue in Central Europe, Eastern and South-East Europe, and Southern Europe, while resistance in P. aeruginosa is additionally problematic in Western Europe. Vancomycin-resistance in E. faecalis is of lesser concern but requires vigilance in E. faecium in Central and Eastern and South-East Europe. In the subcohort of patients with secondary peritonitis presenting with either sepsis or septic shock, the appropriateness of empiric antimicrobial therapy was not associated with mortality. In contrast, failure of source control was strongly associated with mortality. The relevance of these new insights for future recommendations regarding empiric antimicrobial therapy in intra-abdominal infections is discussed.Severe intra-abdominal infection commonly requires intensive care. Mortality is high and is mainly determined by diseasespecific characteristics, i.e. setting of infection onset, anatomical barrier disruption, and severity of disease expression. Recent observations revealed that antimicrobial resistance appears equally common in community-acquired and late-onset hospital-acquired infection. This challenges basic principles in anti-infective therapy guidelines, including the paradigm that pathogens involved in community-acquired infection are covered by standard empiric antimicrobial regimens, and second, the concept of nosocomial acquisition as the main driver for resistance involvement. In this study, we report on resistance profiles of Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Enterococcus faecalis and Enterococcus faecium in distinct European geographic regions based on an observational cohort study on intra-abdominal infections in intensive care unit (ICU) patients. Resistance against aminopenicillins, fluoroquinolones, and third-generation cephalosporins in E. coli, K. pneumoniae and P. aeruginosa is problematic, as is carbapenem-resistance in the latter pathogen. For E. coli and K. pneumoniae, resistance is mainly an issue in Central Europe, Eastern and South-East Europe, and Southern Europe, while resistance in P. aeruginosa is additionally problematic in Western Europe. Vancomycin-resistance in E. faecalis is of lesser concern but requires vigilance in E. faecium in Central and Eastern and South-East Europe. In the subcohort of patients with secondary peritonitis presenting with either sepsis or septic shock, the appropriateness of empiric antimicrobial therapy was not associated with mortality. In contrast, failure of source control was strongly associated with mortality. The relevance of these new insights for future recommendations regarding empiric antimicrobial therapy in intra-abdominal infections is discussed

The DUNE Far Detector Vertical Drift Technology, Technical Design Report

DUNE is an international experiment dedicated to addressing some of the questions at the forefront of particle physics and astrophysics, including the mystifying preponderance of matter over antimatter in the early universe. The dual-site experiment will employ an intense neutrino beam focused on a near and a far detector as it aims to determine the neutrino mass hierarchy and to make high-precision measurements of the PMNS matrix parameters, including the CP-violating phase. It will also stand ready to observe supernova neutrino bursts, and seeks to observe nucleon decay as a signature of a grand unified theory underlying the standard model. The DUNE far detector implements liquid argon time-projection chamber (LArTPC) technology, and combines the many tens-of-kiloton fiducial mass necessary for rare event searches with the sub-centimeter spatial resolution required to image those events with high precision. The addition of a photon detection system enhances physics capabilities for all DUNE physics drivers and opens prospects for further physics explorations. Given its size, the far detector will be implemented as a set of modules, with LArTPC designs that differ from one another as newer technologies arise. In the vertical drift LArTPC design, a horizontal cathode bisects the detector, creating two stacked drift volumes in which ionization charges drift towards anodes at either the top or bottom. The anodes are composed of perforated PCB layers with conductive strips, enabling reconstruction in 3D. Light-trap-style photon detection modules are placed both on the cryostat's side walls and on the central cathode where they are optically powered. This Technical Design Report describes in detail the technical implementations of each subsystem of this LArTPC that, together with the other far detector modules and the near detector, will enable DUNE to achieve its physics goals