Evaluation of Lentil (Lens Culinaris Medik.) Local Varieties in Southeastern Anatolia, Turkey

, and grain yield were found susceptible to environmental differences due to cultivar x year interaction. BM 76 among fourteen cultivars/lines was selected as a promising line in respect of seed weight, early maturing, and high yielded

Achievements and future petspective for gene transfer from wild relatives to the cultivated species in cool season food legumes

The following cultivated crop species, chickpea (Cicer arietinum L.), lentil (Lens culinaris Medik.), pea (Pisum sativum L.) and faba bean (Visa faba L.) in the genera Cicer L., Lens Miller, Pisum L. and Vicia L., respectively; are main diet and calorie sources for human in most part of the world. Selection processes for higher yield and quality characteristics during domestication have resulted in narrowing of the genetic variation in the cultivated crop species of the cool season food legumes. Wild Cicer, Lens, Pisum and Vicia species do not consist of useful variation for morphological characteristics and protein content, but they also possess sources of resistance to biotic and abiotic stresses. The aims of the present study were to review (i) for resistance to abiotic and biotic stresses on wild species of Cicer, Lens, Pisum and Vicia; (ii) on achievements and future perspective for gene transfer from wild species to the cultivated species in cool season food legumes

Inheritance of pod and seed traits in chickpea

Abstract: A 4 x 4 full-diallel cross was studied to estimate the gene effects and genetic parameters of pod and seed traits. According to Hayman's method, additive genetic variance was significant for pod length and seed length and width, also, both additive and dominance genetic variance were significant for pod thickness and width. As additive gene effects were significant for pod and seed traits, it is suggesting the selection of this traits early generations. Partial dominance was important for traits. The high narrow sense heritability of pod and seed traits was between 86 and 97%

Studies on Variability of Lentil Genotypes in Southeastern Anatolia of Turkey

Sixty-four lentil genotypes from ICARDA were evaluated at Diyarbakir, Turkey in 2003/2004 season. Eleven characters were studied. Days to maturity ranged from 188 to 196 days, and some genotypes were earlier than the local check, or same. Total 42 genotypes, suitable for mechanical harvest, were taller than 25 cm plant height. Seed yield per plant varied from 0.5 g to 2.366 g. The genotypes for cold tolerance were determined, and the genotypes of 1-3 scale were selected future lentil-breeding programme. Grain yield ranged from 776.8 kg/ha for FLIP 96-47L to 3242.3 kg/ha for FLIP 2004-49L. Grain yield was positively correlated with days to maturity, biological yield per plant, and plant height, number of seeds and pods per plant and seed yield per plant, negatively correlated with days to flowering and number of branches per plant

Treatment of aggressive non-Hodgkin's lymphoma with dose-intensified epirubicin in combination of cyclophosphamide, vincristine, and prednisone (CEOP-100): a phase II study.

Epirubicin is an agent with a lower incidence of cardiotoxicity and myelotoxicity compared with doxorubicin; and it is active in patients with non-Hodgkin's lymphoma (NHL). Our aim was to define the therapeutic efficacy and toxicity of dose-intensified epirubicin in combination With cyclophosphamide, vincristine, and prednisone (CEOP) in patients with diffuse large-cell NHL. Previously untreated patients aged between 15 and 75 years, with at least one measurable lesion, adequate liver, renal, cardiac functions, and no central nervous system involvement were included in the study. The planned chemotherapy regimen CEOP consisted of cyclophosphamide 750 mg/m(2), epirubicin 100 mg/m2, and vincristine 1.4 mg/m(2) intravenously on day I and 100 mg prednisone taken orally on days I to 5. Courses were repeated every 21 days. Patients With stage I and H received four cycles of chemotherapy followed by involved-field radiotherapy, and patients With stage III and IV received six cycles of chemotherapy followed by radiotherapy to bulky lymph node sites. Seventy-five patients were enrolled in the study. The complete response rate was 83.8%, and 72 patients were assessable for toxicity. The most common toxicity was myelosuppression; 13.9% of the patients had grade III-IV neutropenia. Severe mucositis, diarrhea, and emesis were uncommon (<10%). At a median follow-up period of 41 months, the 5-year progression-free survival and overall survival rates were 63.5% and 65.3%, respectively. Increasing the dose intensity of epirubicin can yield a similar complete response rate compared With the regimens used in NHL Without significantly increasing the toxicity rate associated with chemotherapy. The role of dose-intensive epirubicin should be investigated further in future randomized trials

Epidemiological features of Turkish patients with sarcoidosis

Epidemiological characteristics of sarcoidosis differ according to geographical distribution. The aim of our study was to disclose epidemiological characteristics in our country.The data was collected from investigators, who sent information on newly-diagnosed patients via internet.In 2 years 198 female and 95 mate patients were enrolled to the study (f/m:2.08). Mean age of patients was 44 +/- 13 years (17-90). Mean age of mate patients was 38 12 while mean age of female patients was 48 13 (p < 0.001). 73.4% of patients were nonsmokers (85.4% of females; 48.4% of mates; (p < 0.001)). About 50% of our 293 patients were housewives. Familial sarcoidosis was found in 3 patients' first degree relatives. Estimated annual incidence of sarcoidosis for Turkey was calculated as 4 per 100,000 person.According to our study, 2/3 of sarcoidosis patients were women; mean age of patients was 45 and the disease began 10 years later in female patients. 80% of patients were nonsmokers; negative relation between sarcoidosis and smoking was evident especially in women. Familial sarcoidosis frequency was lower compared to other studies in the literature. There was no occupational exposure history in our patients. Our incidence rate, is similar with the results of other European studies. (C) 2008 Elsevier Ltd. All rights reserved

Epidemiology and distribution of interstitial lung diseases in Turkey

Introduction: There is very few data on the epidemiological features of interstitial lung diseases (ILD) in the literature. These studies on this subject suffer from limited number of patients. Objective: The goal of this study was to evaluate the epidemiological features of ILD in Turkey. Methods: Fifty-four investigators, 31 centres in 19 cities from six regions of Turkey, participated in the study. Two thousand two hundred forty-five newly diagnosed patients (51.8% females), led by Turkish Thoracic Society Clinical Problems Study Group, enrolled in this prospective study. Results: The mean age was 51.8±16.7 years. The mean age among males was 50.5±18.6 years and 53.0±14.6 years among females (P<0.001). 23.8% of the cases had ILD with known causes, while 39.4% were in granulomatous group, 23.7% were idiopathic, and 4.4% were in the unclassified group. Overall, histopathologically confirmed diagnosis rate was 40.4%. Sarcoidosis was the most common disease (37%), whereas cases with idiopathic pulmonary fibrosis (IPF) constituted 19,9% of patients. 53% of the sarcoidosis patients were females, and the ratio reaches to 75% under 50 years of age (for this group, IPF ratio is %3). In contrast, sarcoidosis and IPF ratios were equal in males (25%). Sarcoidosis was 8% in men over 50, while IPF was %45. Conclusion: The overall incidence of ILD in Turkey was computed to be 25.8/100000. © 2013 John Wiley & Sons Ltd