Large Area Crop Inventory Experiment (LACIE). The Z-index and subitaneous events as variables for estimating wheat yields in Argentina

There are no author-identified significant results in this report

Gauge-Fixing and Residual Symmetries in Gauge/Gravity Theories with Extra Dimensions

We study compactified pure gauge/gravitational theories with gauge-fixing terms and show that these theories possess quantum mechanical SUSY-like symmetries between unphysical degrees of freedom. These residual symmetries are global symmetries and generated by quantum mechanical N=2 supercharges. Also, we establish new one-parameter family of gauge choices for higher-dimensional gravity, and calculate as a check of its validity one graviton exchange amplitude in the lowest tree-level approximation. We confirm that the result is indeed $\xi$-independent and the cancellation of the $\xi$-dependence is ensured by the residual symmetries. We also give a simple interpretation of the vDVZ-discontinuity, which arises in the lowest tree-level approximation, from the supersymmetric point of view.Comment: REVTeX4, 17 pages, 1 figur

Large Area Crop Inventory Experiment (LACIE). USSR spring and winter wheat models, addendum

There are no author-identified significant results in this report

Large Area Crop Inventory Experiment (LACIE). A wheat yield model for Brazil

There are no author-identified significant results in this report

LACIE transition protect, FY 1978-1979: Reanalysis of CCEA 1 US Great Plains wheat yield models

There are no author-identified significant results in this report

Large Area Crop Inventory Experiment (LACIE). an Index for Estimating Wheat Yield in Australia

There are no author-identified significant results in this report

Extended supersymmetry and its reduction on a circle with point singularities

We investigate $N$-extended supersymmetry in one-dimensional quantum mechanics on a circle with point singularities. For any integer $n$, $N=2n+1$ supercharges are explicitly constructed in terms of discrete transformations, and a class of singularities compatible with supersymmetry is clarified. In our formulation, the supersymmetry can be reduced to $M$-extended supersymmetry for any integer $M<N$. The degeneracy of the spectrum and spontaneous supersymmetry breaking are also studied.Comment: 36 pages, 5 figures, 2 table

Expression profile of CREB knockdown in myeloid leukemia cells.

BackgroundThe cAMP Response Element Binding Protein, CREB, is a transcription factor that regulates cell proliferation, differentiation, and survival in several model systems, including neuronal and hematopoietic cells. We demonstrated that CREB is overexpressed in acute myeloid and leukemia cells compared to normal hematopoietic stem cells. CREB knockdown inhibits leukemic cell proliferation in vitro and in vivo, but does not affect long-term hematopoietic reconstitution.MethodsTo understand downstream pathways regulating CREB, we performed expression profiling with RNA from the K562 myeloid leukemia cell line transduced with CREB shRNA.ResultsBy combining our expression data from CREB knockdown cells with prior ChIP data on CREB binding we were able to identify a list of putative CREB regulated genes. We performed extensive analyses on the top genes in this list as high confidence CREB targets. We found that this list is enriched for genes involved in cancer, and unexpectedly, highly enriched for histone genes. Furthermore, histone genes regulated by CREB were more likely to be specifically expressed in hematopoietic lineages. Decreased expression of specific histone genes was validated in K562, TF-1, and primary AML cells transduced with CREB shRNA.ConclusionWe have identified a high confidence list of CREB targets in K562 cells. These genes allow us to begin to understand the mechanisms by which CREB contributes to acute leukemia. We speculate that regulation of histone genes may play an important role by possibly altering the regulation of DNA replication during the cell cycle