An Intracranial Hemorrhage Wrapped in an Enigma

An 88-year-old man with Alzheimer's dementia who previously received a diagnosis of solitary Fuhrman grade 2 renal cell carcinoma1 managed with active surveillance presented to the emergency department for progressive left-sided headache and difficulty recognizing numbers and letters. He and his family denied history of trauma, fall, or anticoagulant use. This occurred 1 week after presenting to the same emergency department with a headache and being discharged home after negative head computed tomography, 2 months after spontaneous subarachnoid hemorrhage involving the right central sulcus, and 11 months after transient ischemic attack symptoms with negative workup

Neutron Diffraction Study on Single-crystalline UAu2{_2}Si2_2

Magnetic structure of tetragonal UAu$_2$Si$_2$ was investigated by single-crystal neutron diffraction experiments. Below $T_{\rm N}$ = 20 K it orders antiferromagnetically with a propagation vector of $k = (2/3, 0, 0)$ and magnetic moments of uranium ions pointing along the tetragonal $c$-axis. Weak signs of the presence of a ferromagnetic component of magnetic moment were traced out.Taking into account a group theory calculation and experimental results of magnetization and $^{29}$Si-NMR, the magnetic structure is determined to be a squared-up antiferromagnetic structure, with a stacking sequence ($+ + -$) of the ferromagnetic $ac$-plane sheets along the $a$-axis. This result highlights similar magnetic correlations in UAu$_2$Si$_2$ and isostructural URu$_2$Si$_2$.Comment: 7 pages, 7 figure

Prevalence of Giardia intestinalis and other zoonotic intestinal parasites in private household dogs of the Hachinohe area in Aomori prefecture, Japan in 1997, 2002 and 2007

An epidemiological study on canine intestinal parasites was undertaken to evaluate changes in the prevalence among private household dogs from the Hachinohe region of Aomori prefecture, Japan, in 1997, 2002 and 2007, using the formalin-ethyl acetate sedimentation technique. The risk of zoonotic transmission from household dogs to humans was also discussed. All intestinal parasites detected in the present study (Giardia intestinalis, Isospora spp., Toxocara canis, Ancylostoma caninum, Trichuris vulpis and Strongyloides stercoralis) showed no changes in prevalence over the past 10 years based on analysis considering canine epidemiological profiles. In particular, prevalence of Giardia intestinalis in dogs under 1 year old, derived from pet shops/breeding kennels and kept indoors was unchanged, remaining at a high level of >15.0% at each time point. Toxocara canis also showed no changes in the group of dogs under 1 year old, bred by private owners and kept outdoors, and the prevalence was >10.0% every year. The present results indicate that the prevalence of Giardia intestinalis and other intestinal parasites in private household dogs has not always decreased, and the potential for direct parasitic zoonotic transmission from dogs to humans may be relatively high level, than from the environment (indoors and outdoors). We recommend careful surveillance of intestinal parasites and aggressive use of anthelminthic in private household dogs under considering the epidemiological factors

NO_3^--N Flux of Streams in the Setouchi Region : Effects of Fruit-Farmland Area, Water Reservoir, and Alluvial Fan

To confirm the effects of fruit-farmland area, water reservoir, and alluvial fan on nitrate load in short streams, we measured runoff and collected water samples at five or eight sites in each of four streams, Seto Inland Sea catchment. Nitrate load of the streams increased with increasing ratio of fruit-farmland area. At a downstream site of water reservoir, nitrate concentration showed a slight decrease. On the area widely domi- nated by alluvial fan, it assumed that groundwater pollution by nitrate-nitrogen is accelerated with groundwater recharge of stream water. It is necessary for conservation of water resources to consider function of these effects as well as river-groundwater mixing

Mitigating the impact of fiber assignment on clustering measurements from deep galaxy redshift surveys

We examine the impact of fiber assignment on clustering measurements from fiber-fed spectroscopic galaxy surveys. We identify new effects which were absent in previous, relatively shallow galaxy surveys such as Baryon Oscillation Spectroscopic Survey . Specifically, we consider deep surveys covering a wide redshift range from z=0.6 to z=2.4, as in the Subaru Prime Focus Spectrograph survey. Such surveys will have more target galaxies than we can place fibers on. This leads to two effects. First, it eliminates fluctuations with wavelengths longer than the size of the field of view, as the number of observed galaxies per field is nearly fixed to the number of available fibers. We find that we can recover the long-wavelength fluctuation by weighting galaxies in each field by the number of target galaxies. Second, it makes the preferential selection of galaxies in under-dense regions. We mitigate this effect by weighting galaxies using the so-called individual inverse probability. Correcting these two effects, we recover the underlying correlation function at better than 1 percent accuracy on scales greater than 10 Mpc/h.Comment: 17 pages, 11 figure

Mass-Metallicity Relation for the Local Group Dwarf Spheroidal Galaxies: A New Picture for the Chemical Enrichment of Galaxies in the Lowest Mass Range

The virial mass ($M_{\rm vir}$)-metallicity relation among the Local Group dwarf spheroidal galaxies (dSphs) is examined. Hirashita, Takeuchi, & Tamura showed that the dSphs can be divided into two distinct classes with respect to the relation between their virial masses and luminosities: low-mass (M_{\rm vir} \la 10^8 M_\odot) and high-mass (M_{\rm vir} \ga 10^8 M_\odot) groups. We see that both the mass-metallicity and the mass-luminosity relations of the high-mass dSphs are understood as a low-mass extension of giant ellipticals. On the contrary, we find that the classical galactic-wind model is problematic to apply to the low-mass dSphs, whose low binding energy is comparable to that released by several supernova explosions. A strongly regulated star formation in their formation phase is required to reproduce their observed metallicity. Such regulation is naturally expected in a gas cloud with the primordial elemental abundance according to Nishi & Tashiro. A significant scatter in the mass-metallicity relation for the low-mass dSphs is also successfully explained along with the scenario of Hirashita and coworkers. We not only propose a new picture for a chemical enrichment of the dSphs, but also suggest that the mass-metallicity and the mass-luminosity relations be understood in a consistent context.Comment: 14 pages LaTeX, 1 PostScript figure, to appear in ApJ Lette

The biosynthetic pathway of potato solanidanes diverged from that of spirosolanes due to evolution of a dioxygenase

ジャガイモの毒α-ソラニンはトマトの苦味成分から分岐進化したことを解明. 京都大学プレスリリース. 2021-03-03.Potato (Solanum tuberosum), a worldwide major food crop, produces the toxic, bitter tasting solanidane glycoalkaloids α-solanine and α-chaconine. Controlling levels of glycoalkaloids is an important focus on potato breeding. Tomato (Solanum lycopersicum) contains a bitter spirosolane glycoalkaloid, α-tomatine. These glycoalkaloids are biosynthesized from cholesterol via a partly common pathway, although the mechanisms giving rise to the structural differences between solanidane and spirosolane remained elusive. Here we identify a 2-oxoglutarate dependent dioxygenase, designated as DPS (Dioxygenase for Potato Solanidane synthesis), that is a key enzyme for solanidane glycoalkaloid biosynthesis in potato. DPS catalyzes the ring-rearrangement from spirosolane to solanidane via C-16 hydroxylation. Evolutionary divergence of spirosolane-metabolizing dioxygenases contributes to the emergence of toxic solanidane glycoalkaloids in potato and the chemical diversity in Solanaceae