Solvability of nondensely defined partial functional integrodifferential equations using the integrated resolvent operators

In this work, we study the existence and regularity of solutions for a class of nondensely defined partial functional integrodifferential equations. We suppose that the undelayed part admits an integrated resolvent operator in the sense given by Oka [J. Integral Equations Appl. 7(1995), 193–232.]. We give some sufficient conditions ensuring the existence, uniqueness and regularity of solutions. The continuous dependence on the initial data of solutions is also proved. Some examples are provided to illustrate our abstract theory

ADPIC et brevets pharmaceutiques: le difficile accès des pays en développement aux médicaments?

L'Accord sur les Aspects des Droits de Propriété Intellectuelle qui touchent au commerce constitue l'un des principaux piliers des accords de l'Uruguay Round. C'est aussi l'un des plus controversés. Cet Accord renforce les droits de propriété intellectuelle, les associe au commerce et introduit une norme mondiale ayant force exécutoire. La mise en application de cet Accord, qui suppose notamment de reconnaître et de renforcer la protection des produits et procédés pharmaceutiques par des brevets, pose des problèmes particuliers aux pays en développement vu le manque de ressources professionnelles, financières et d'infrastructure. La manière dont se fait l'interprétation de cet Accord peut avoir d'importantes répercussions sur les politiques de santé publique et, en particulier, sur l'accès des populations aux médicaments. Soumis aux pressions des pays riches et des groupes pharmaceutiques, les gouvernements des pays en développement se retrouvent parfois pieds et poings liés et n'utilisent pas les flexibilités prévues à leur avantage dans l'Accord, ce qui rend la situation sanitaire de leur population encore plus précaire. Cette étude décrit les principaux acteurs et les étapes importantes de la négociation de l'Accord, ainsi que les différentes adaptations qui en ont été faites sous les pressions contradictoires des nombreux protagonistes. Elle donne des explications sur les mécanismes en place et les conséquences possibles de l'entrée en vigueur de l'Accord sur l'accessibilité des pays en développement aux médicaments.The Agreement on Trade-Related Aspects of Intellectual Property Rights is one of the main pillars of the agreements of the Uruguay Round. It is also one of the most controversial. This agreement strengthens the intellectual property rights, ties them to trade regulation and introduces a global binding standard. The implementation of this Agreement, which includes the recognition and the strengthening of the protection of pharmaceutical products and processes by patents, raises particular problems for developing countries, given the in lack of professional over financial resources as well as their poor economics infrastructure. The interpretation of this Agreement can have important consequences on public health policies and in particular on people's access to medicines. Unless the pressure of rich countries and pharmaceutical companies, governments of developing countries sometimes find themselves bound hand and foot and do not use the flexibilities provided to them by the Agreement to improve their position, thus making the health situation of their people still more precarious. This study describes the main actors and the important stages of negotiating the Agreement, as well as the various adjustments that were made under the pressures of numerous actors. It provides explanations of the existing mechanisms and of the potential consequences of the implementation of the Agreement on the accessibility of developing countries to medicines

Capture de mouvement par mesure de distances dans un réseau corporel hétérogène

La capture de mouvement ambulatoire est un sujet en plein essor pour des applications aussi diverses que le suivi des personnes âgées, l'assistance des sportifs de haut niveau, la réhabilitation fonctionnelle, etc. Ces applications exigent que le mouvement ne soit pas contraint par un système externe, qu il puisse être réalisé dans différentes situations, y compris en extérieur, que l équipement soit léger et à un faible coût, qu il soit réellement ambulatoire et sans procédure complexe de calibration.Actuellement, seuls les systèmes utilisant un exosquelette ou bien des modules inertiels (souvent combinés avec des modules magnétiques) permettent d'effectuer de la capture de mouvement de façon ambulatoire. Le poids de l exosquelette est très important et il impose des contraintes sur les mouvements de la personne, ce qui le rend inutilisable pour certaines applications telles que le suivi de personnes âgées. La technologie inertielle est plus légère. Elle permet d'effectuer la capture du mouvement sans contrainte sur l espace de mesure ou sur les mouvements réalisés. Par contre, elle souffre de dérives des gyromètres, et le système doit être recalibré.L'objectif de cette thèse est de développer un système de capture de mouvement de chaînes articulées, bas-coût et temps réel, réellement ambulatoire, ne nécessitant pas d'infrastructure de capture spécifique, permettant une utilisation dans de nombreux domaines applicatifs (rééducation, sport, loisirs, etc.).On s'intéresse plus particulièrement à des mesures intra-corporelles. Ainsi, tous les capteurs sont placés sur le corps et aucun dispositif externe n'est utilisé. Outre un démonstrateur final permettant de valider l'approche proposée, on s'astreint à développer également des outils qui permettent de dimensionner le système en termes de technologie, nombre et position des capteurs, mais également à évaluer différents algorithmes de fusion des données. Pour ce faire, on utilise la borne de Cramer-Rao.Le sujet est donc pluridisciplinaire. Il traite des aspects de modélisation et de dimensionnement de systèmes hybrides entièrement ambulatoires. Il étudie des algorithmes d'estimation adaptés au domaine de la capture de mouvement corps entier en traitant les problématiques d'observabilité de l'état et en tenant compte des contraintes biomécaniques pouvant être appliquées. Ainsi, un traitement adapté permet de reconstruire en temps réel la posture du sujet à partir de mesures intra-corporelles, la source étant également placée sur le corps.Ambulatory motion capture is of great interest for applications ranging for the monitoring of elderly people, sporty performances monitoring, functional rehabilitation, etc. These applications require that the movement is not constrained by an external system, that it can be performed in different situations, including outdoor environment. It requires lightweight and low cost equipment; it must be truly ambulatory without complex process of calibration.Currently, only systems using an exoskeleton or inertial modules (often combined with magnetic modules) can be used in such situations. Unfortunately, the exoskeleton weight is not affordable and it imposes constraints on the movements of the person, which makes it unusable for certain applications such as monitoring of the elderly.Inertial technology is lighter. Itcan be used for the capture of movement without constraints on the capture space or on the movements. However, it suffers from gyros drift, and the system must be recalibrated.The objective of this thesis is to develop a system of motion capture for an articulated chain, low-cost, real-time truly ambulatory that does not require specific capture infrastructure, that can be used in many application fields (rehabilitation, sport, leisure, etc.).We focus on intra-corporal measurements. Thus, all sensors are placed on the body and no external device is used. In addition to a final demonstrator to validate the proposed approach, we also develop tools to evaluate the system in terms of technology, number and position of sensors, but also to evaluate different algorithms for data fusion. To do this, we use the Cramer-Rao lower bound. \\The subject is multidisciplinary. It addresses aspects of modelling and design of fully ambulatory hybrid systems. It studies estimation algorithms adapted to the field of motion capture of a whole body by considering the problem of observability of the state and taking into account the biomechanical constraints that can be taken into account. Thus, with an appropriate treatment, the pose of a subject can be reconstructed in real time from intra-body measurements.SAVOIE-SCD - Bib.électronique (730659901) / SudocGRENOBLE1/INP-Bib.électronique (384210012) / SudocGRENOBLE2/3-Bib.électronique (384219901) / SudocSudocFranceF

On Optimizing Backup Sharing Through Efficient VNF Migration

With the emergence of software defined networking and network function virtualization technologies, network services are expected to be offered as service function chains made out from virtual network functions that are connected to steer and process the incoming traffic. In this context, achieving the survivability of these chains against failures is a key challenge to ensure high availability and continuity of the services. A promising solution proposed in the literature is to provision backups for the virtual network functions that could be shared among multiple service chains. These backups are used in case of a failure to take over the failed functions and ensure service continuity. In this paper, we propose two solutions to efficiently place and provision the shared backups in order to ensure the survivability of the service chains against single node failures. The originality of these solutions is that they leverage the migration of virtual network functions to minimize the resources consumed by the backups. Simulation results show that, compared to existing solutions, the proposed schemes leveraging migration are able to reduce by up to 20% the amount of resources allocated for the shared backups while ensuring the survivability of the service chains

On improving Service Chains Survivability Through Efficient Backup Provisioning

With the growing adoption of Software Defined Networking (SDN) and Network Function Virtualization (NFV), large-scale NFV infrastructure deployments are gaining momentum. Such infrastructures are home to thousands of network Service Function Chains (SFCs), each composed of a chain of virtual network functions (VNFs) that are processing incoming traffic flows. Unfortunately, in such environments, the failure of a single node may break down several VNFs and thereby breaking many service chains at the same time. In this paper, we address this particular problem and investigate possible solutions to ensure the survivability of the affected service chains by provisioning backup VNFs that can take over in case of failure. Specifically, we propose a survivability management framework to efficiently manage SFCs and the backup VNFs. We formulate the SFC survivability problem as an integer linear program that determines the minimum number of required backups to protect all the SFCs in the system and identifies their optimal placement in the infrastructure. We also propose two heuristic algorithms to cope with the large-scale instances of the problem. Through extensive simulations of different deployment scenarios, we show that these algorithms provide near-optimal solutions with minimal computation time

Study of Some New Entolomes Species for Fungal Flora of Morocco

In this study, four species of Entolomataceae family, were studied namely Entoloma papillatum, Entoloma rhodopolium, Nolanea hirtipes and N. cucullata are harvested for the first time in Morocco. The genus Entoloma' species were encountered in Quercus suber in the forest of Mamora (Northwestern Morocco) and those of the Nolanea' genus under Quercus rotundifolia in the forest El Harcha (Northeast of the Central Plateau)

TUNWeeds: A Smart Identification Tool for Brassicaceae Weeds in Rapeseed (Brassica napus) Crop in Tunisia

Rapeseed is the second oilseed in the world. Its cultivation requires successful weed control. Weed identification is critical in weed management programs. Two surveys of common weeds in rapeseed fields allowed us to identify a wide specific diversity of weed flora and a great identification difficulty of certain specimens. To facilitate this task, we have developed a web application (TUNWeeds) for Tunisian farmers and students. At first, we limited our database to 44 Brassicaceae weeds. Subsequently, we plan to extend this application to other botanical families. TUNWeeds can help farmers in chemical weed control, manage herbicide resistance problems, and monitor weed flora

Potential of Aquatic Plants for Pesticide Removal in Wastewater: A Case Study on Pentachlorophenol

Today, soil and water pollution by pesticides is a serious problem worldwide. Compared with conventionally expensive, invasive, and sometimes ineffective techniques for pentachlorophenol (PCP) dealing, such as excavation, dredging and some chemical methods, in situ treatment strategies are more effective at reducing risk and decreasing expenditures on management. Among the in situ treatments, bioremediation (microbial remediation and phytoremediation) is thought to be capable in permanent pollutants elimination at low cost. Therefore, phytoremediation has received more attention in the last decade. Phytoremediation is applicable owing to its esthetic value, environment friendly, manipulation in situ and economic benefit. However, the previous phytoremediation studies mostly focused on the use of terrestrial plants and remediation of heavy metals. Sediments in aquatic environment are regarded as ultimate sink of organic contaminants, but little information is available on the possibility of use of aquatic macrophytes for remediation of organic toxicants in aquatic environment. It is, therefore, necessary to develop phytoremediation method of PCP by using aquatic macrophytes