Präferenzen von Patienten hinsichtlich Information und Teilhabe an der Entscheidungsfindung in der Onkologie

Ziel war es, zu überprüfen, in wieweit das Partizipations- und Informationsbedürfnis von Patienten mit gastrointestinalen Tumoren mit präferenzsensitiver Entscheidung in einer Studie untersucht werden kann. Die Daten wurden prospektiv anhand des API und PEF-FB-9 sowie anhand des Fragebogens zu soziodemographischen Daten und psycho-sozialer Belastung gesammelt. Die Befragung erfolgte postoperativ vor und nach dem Aufklärungsgespräch zur möglichen adjuvanten Therapie. Die Studie war unter Modifizierung der Befragungsmethodik machbar. Zusätzlich wurde ein deutliches Informationsbedürfnis evident. Es konnten Kriterien der Befragung identifiziert werden. Patienten mit einem Kolon- oder Rektumkarzinom nehmen keine passive oder paternalistische Rolle ein, sondern bevorzugen eine Beteiligung im Sinne des Shared decision making. Zur Erfassung des individuellen Patientenbedürfnisses sollten die Messinstrumente fest in die klinische Routine und in die Nachsorge eingebaut werden

Secondary radiological findings of osteoid osteoma as muscular atrophy and synovitis in paediatric and adult patients

Purpose: Diagnosis of osteoid osteoma may be delayed if secondary radiological findings such as muscle atrophy, oedema in peripheric soft tissue and bone marrow, joint effusion, or synovitis are more severe than the lesion itself. In this article, the purpose was to demonstrate secondary radiological findings of osteoid osteoma in both paediatric and adult patients. This study is one of the very few with such a large case series. Material and methods: Radiological images of 152 patients were reviewed retrospectively. Peri-nidus sclerosis, periosteal reactive bone formation, bone marrow and soft tissue oedema, presence of synovial effusion, muscular atrophy in the affected extremity, osteopaenia, and posture deterioration were noted. Results: Most of the lesions (87.5%) were localised in lower extremity bones. Among all the patients, 56% had extraarticular (65% in paediatric patients) and 44% had intraarticular (69% in paediatric patients) osteoid-osteoma. In 44% of the patients, synovial effusion was presented. In 89.4% of these, osteoid osteoma was localised in the joint. Of the 97 patients who had osteoid osteoma in lower extremities or pelvic bones, 73% had muscular atrophy. In 6% of them muscular atrophy was severe, and they had posture-gait disorder with accompanying osteopaenia. In 48% of the patients, there was reactive periosteal bone formation around the nidus. Conclusions: Secondary radiological findings, such as muscular atrophy, synovitis, posture-gait deterioration, and reactive bone formation in a patient with continuous pain that is relieved by anti-inflammatory drugs may point to an osteoid osteoma

Spontaneous pneumothorax and subcutaneous emphysema in COVID-19 patient: Case report

Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome virus coronavirus 2 (SARS-CoV-2). As known, COVID-19 has become a global pandemic and serious health problem. Disease mainly affects lungs and common findings are fever cough and shortness of breath. Computerized tomography (CT) has an important role in initial evaluation and follow up of COVID-19. Main (CT) finding of the disease is bilateral extensive ground-glass opacification (GGO) with a peripheral or posterior distribution, mainly involving the lower lobes. In this case report, we present a pneumothorax and subcutaneous emphysema case in a patient with COVID-19. To the best of authors’ knowledge, it is the first illustrated case of pneumothorax accompanying COVID-19 pneumonia

Complications of Computer Tomography Assisted Radiofrequency Ablation in the Treatment of Osteoid Osteoma

Background. Osteoid osteoma (OO) is one of the most commonly occurring benign bone tumors. It constitutes 10-12% of benign bone tumors and 2-3% of primary bone tumors. In radiofrequency ablation (RFA) treatment, the cells of the tumor are thermally inactivated by the help of electrodes shaped like needles. In our study, we aimed to show the major and minor complications in patients undergoing RFA and to show what should be done to prevent these complications. Methods. The study was carried out as a prospective study on the follow-up of 87 osteoid osteoma patients treated between 2015 and 2017. The youngest of the patients was 1 year old and the oldest was 42 years old. The RFA procedure lasted 10 min on average, excluding anesthesia and preparation. All lesions were ablated at 90 degrees for 7 minutes with the heat increased gradually. All patients were followed up for 1 day in the orthopedics clinic. Results. Complications were observed in 7 patients. The lesions with the most complications were observed to be in the tibia, second-degree burns were seen in 2 patients, and superficial skin infection was observed in 2 patients. In 1 patient, the probe tip was broken and remained within the bone. Intramuscular hematoma was detected in 1 lesion located in the proximal femur. A complaint of numbness in the fingers developed in a lesion located in the metacarpus. Conclusion. Preventive measures should be taken before the procedure in order to prevent minor complications, and, for major complications, close follow-up should be done after the procedure and patients should be kept away from heavy physical activities for the first 3 months

Variability in salinity stress tolerance of potato (Solanum tuberosum L.) varieties using in vitro screening

Salinity is one of the abiotic stresses that lead to an imbalance in the physiological processes of the plants and also affects potato growth and productivity in mainly semi-arid and growing areas. The accumulation of Na+ and Cl-ions in the cells is very toxic can influence all mechanisms and the enzymatic actions of the plants. In vitro screening of plant genotypes for osmotic stress represents a valuable tool as an alternative to field trials and can be applied based on osmotic stress tolerance. The main goal of this study was to reveal variability in salinity stress tolerance of potato varieties using in vitro screening. Stem cuttings consisting of a single node of different varieties were cultured on Murashige and Skoog (MS) medium supplemented with different concentrations of sodium chloride (NaCl) (0, 50, 100 and 150 mM). The differences among the plantlet length, number of branches, number of nodes, number of the leaflet, leaflet width, leaflet length, root length, number of the root, fresh plantlet weight, dry plantlet weight of all varieties were negatively influenced by all NaCl concentrations tested. Microtuberization and stolon growth of the varieties were also completely inhibited at high concentrations (100-150 mM). The Principal components analysis (PCA) was applied to the data matrix (15 morphological characteristics x 12 potato varieties) of the potato varieties. Also, a hierarchical cluster analysis (HCA) was used to identify the possible nearest and similarity of all morphological characteristics analyzed of the potato varieties. In grouping potato varieties, HCA and PCA results were found to be similar. We can speculate about the responses of morphological similarities of the potato varieties against salt stress. We concluded that Innovator and Kennebec are respectively the most salt-tolerant varieties. Hermes was moderately salt-tolerant and microtuberization capacity of Slaney was also high under salt stress conditions

Bahcesehir long-term population-based screening compared to National Breast Cancer Registry Data: effectiveness of screening in an emerging country

PURPOS

Cost-Effectiveness of Breast Cancer Screening in Turkey, a Developing Country: Results from Bahcesehir Mammography Screening Project

Objective: We used the results from the first three screening rounds of Bahcesehir Mammography Screening Project (BMSP), a 10-year (20092019) and the first organized population-based screening program implemented in a county of Istanbul, Turkey, to assess the potential cost-effectiveness of a population-based mammography screening program in Turkey

Poor Biological Factors and Prognosis of Interval Breast Cancers: Long-Term Results of Bahceehir (Istanbul) Breast Cancer Screening Project in Turkey

PURPOSE The Turkish Bahceehir Breast Cancer Screening Project was a 10-year, organized, population-based screening program carried out in Bahceehir county, Istanbul. Our aim was to examine the biologic features and outcome of screen-detected and interval breast cancers during the 10-year study period

Radiologic findings of screen-detected cancers in an organized population-based screening mammography program in Turkey

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