80 research outputs found
Milet
İonya, MÖ 1000’lerde 12 İon koloni şehrinin birlikteliğiyle oluşmuştur. İonlar bir denizci topluluğuydu ve kültürel etkileşimleri, halkına sunduğu özgür- lükçü alan onların düşünsel duruşunun önemli nedenlerindendi. İonya do- ğayı anlama, görünenin ve değişenin ardında yatan değişmeyen temel ilkenin ne olduğu konusunda rasyonel bir tutumun, girişimin ortaya konduğu önemli bir merkezdi. Bu 12 şehirden en önemlisiyse Milet’t
Dress Culture-Related Adaptation Problems Faced by Turkish Women Living Abroad
This study, which was carried out in order to identify the problems faced by Turkish women living abroad with respect to dress culture, is a descriptive study based on a scan model. The sample group for this study comprised 394 Turkish women aged 20 and over living in London in the United Kingdom, which is home to many cultures as well as its own specific culture. As a result of an analysis of the data obtained from the survey prepared by the researcher it was determined that people coming to London from the major cities in Turkey encountered fewer problems with respect to dress culture than people coming from towns and villages in Turkey, and that people with an income of less than £1,000 a month experienced more problems than people with a higher level of income. Furthermore, it was also determined that the sample group aged 50 and over experienced more adaptation problems with respect to dress culture, and that these problems were generally due to the length of clothing and how revealing it was
Diagnosis of Variant Klinefelter Syndrome in a 21-Year-Old Male Who Presented with Sparse Facial Hair
Why do some patients with stage 1A and 1B endometrial endometrioid carcinoma experience recurrence? A retrospective study in search of prognostic factors
Objectives: Endometrial endometrioid carcinoma (EEC) is the most encountered subtype of endometrial cancer (EC). Our study aimed to investigate the factors affecting recurrence in patients with stage 1A and 1B EEC.
Material and methods: Our study included 284 patients diagnosed with the International Federation of Gynecology and Obstetrics stage 1A/1B EEC in our center from 2010 to 2018. The clinicopathological characteristics of the patients were obtained retrospectively from their electronic files.
Results: The median age of the patients was 60 years (range 31–89). The median follow-up time of the patients was 63.6 months (range 3.3–185.6). Twenty-two (7.74%) patients relapsed during follow-up. Among the relapsed patients, 59.1% were at stage 1A ECC, and 40.9% were at stage 1B. In our study, the one-, three-, and five-year recurrence-free survival (RFS) rates were 98.9%, 95.4%, and 92.9%, respectively. In the multivariate analysis, grade and tumor size were found to be independent parameters of RFS in all stage 1 EEC patients. Furthermore, the Ki-67 index was found to affect RFS in stage 1A EEC patients, and tumor grade affected RFS in stage 1B EEC patients. In the time-dependent receiver operating characteristic curve analysis, the statistically significant cut-off values were determined for tumor size and Ki-67 index in stage 1 EEC patients.
Conclusions: Stage 1-EEC patients in the higher risk group in terms of tumor size, Ki-67, and grade should be closely monitored for recurrence. Defining the prognostic factors for recurrence in stage 1 EEC patients may lead to changes in follow-up algorithms
The impact of Ki-67 index, squamous differentiation, and several clinicopathologic parameters on the recurrence of low and intermediate-risk endometrial cancer
Endometrial endometrioid carcinoma (EEC) represents approximately 75-80% of endometrial carcinoma cases. Three hundred and thirty-six patients with EEC followed-up in the authors’ medical center between 2010 and 2018 were included in our study. Two hundred and seventy-two low and intermediate EEC patients were identified using the European Society for Medical Oncology criteria and confirmed by histopathological examination. Recurrence was reported in 17 of these patients. The study group consisted of patients with relapse. A control group of 51 patients was formed at a ratio of 3:1 according to age, stage, and grade, similar to that in the study group. Of the 17 patients with recurrent disease, 13 patients (76.5%) were Stage 1A, and 4 patients (23.5%) were Stage 1B. No significant difference was found in age, stage, and grade between the case and control groups (p > 0.05). Body mass index, parity, tumor size, lower uterine segment involvement, SqD, and Ki-67 index with p<0.25 in the univariate logistic regression analysis were included in the multivariate analysis. Ki-67 was statistically significant in multivariate analysis (p = 0.018); however, there was no statistical significance in SqD and other parameters. Our data suggest that the Ki-67 index rather than SqD needs to be assessed for recurrence in patients with low- and intermediate-risk EEC
Determinants of diet-related support provision between patients with type 2 diabetes and their spouses
This study investigated determinants of diet-related support using Dunkel-Schetter and Skokan\u27s (1990) multifactorial model. For patients with type 2 diabetes and their spouses (N = 56 couples), each partner\u27s attachment anxiety and attachment avoidance was conceptualized as provider and recipient factors, marital satisfaction was examined as relationship factor, diet adherence and HbA1c were explored as stress factors. Spouses\u27 own attachment anxiety and attachment avoidance, as well as patients\u27 diet adherence were found to be predictors of spouses\u27 diet-related support provision. In addition, findings revealed that patients with type 2 diabetes promote healthy eating habits of their spouses through diet-related support. Patients\u27 marital satisfaction and spouses\u27 following a healthy eating plan were associated with patients\u27 provision of diet-related support to their spouses. Findings of this study support the perspective that provision of support is multiply determined and extend beyond characteristics of the provider to include the broader relational context of patients and their spouses
The effects of different fatty acids on nesfatin-1, omentin-1, adropin, leptin and ghrelin levels
There are many studies on nesfatin-1, omentin, adropin, leptin, and ghrelin. However, data on the effects of long, medium, and short chain fatty acids on serum/tissue concentrations of nesfatin-1, omentin, adropin, leptin, and ghrelin are scarce. This study aims to investigate the effects of butyric acid, caprylic acid, and oleic acid alone or in combination on nesfatin-1, omentin, adropin, leptin, and ghrelin secretion. In the study, 49 male Wistar rats were used. The rats were randomly divided into 7 groups as control (CONT), butyric acid (BA), caprylic acid (CA), oleic acid (OA), butyric acid+caprylic acid (BA+CA), butyric acid+oleic acid (BA+OA) and caprylic acid+oleic acid (CA+OA) groups. The rats were orally administered fatty acids for twenty-one days. At the end of the study, the levels of nesfatin-1, omentin, adropin, leptin, and ghrelin were determined by the ELISA method. When the groups were compared in terms of nesfatin-1, omentin, adropin, leptin, and ghrelin levels, the butyric acid group had higher nesfatin-1, omentin, adropin, leptin, and ghrelin levels than the other groups (p0.05). In conclusion, it was observed that butyric acid use caused an increase in serum nesfatin-1, omentin, adropin, leptin, and ghrelin levels. [Med-Science 2023; 12(4.000): 1117-23
Examining Usage Trends of Computer Support of the Prospective Primary School Teachers in the Science Education Based on the 5E Model
5th World Conference on Educational Sciences (WCES) -- FEB 05-08, 2013 -- Rome Sapienza Univ, Rome, ITALYWOS: 000335471202003The purpose of this study is to examine usage trends of computer support (CS) of Prospective Primary School Teachers (PPST) in science education based on the 5E instruction model. The research was designed according to the case study method. The sample of the study composed of 154 PPST. The PPTS were trained about the 5E model in the science teaching course. Data were collected through open ended questions which are prepared by researchers. These questions were about PPST used CS in their instructions in the 5E but 'why? in which stage of model? and which websites they used?' Data were analyzed with content analysis and their frequencies were calculated. In data analyses, PPST' statements related to their aims about usage of CS such as animations and videos etc. were coded. Results indicated that all of the PPST benefit from the national web sites and they prefer to use animation and videos in 'engage' and 'explanation' stage of the 5E model. Results also showed that PPST will use CS to attract students' attention in the 'engage' stage and explain visually in the 'explanation' stage. (C) 2013 The Authors. Published by Elsevier Ltd. Selection and/or peer-review under responsibility of Academic World Education and Research Center.Near E Univ, Ankara Univ, Bahcesehir Uni
The effects of adding various ratios of zirconium oxide nanoparticles to poly(methyl methacrylate) on physical and mechanical properties.
The aim of the present study is to evaluate the transverse strength, modulus of elasticity, surface roughness, hardness, and water sorption/solubility of nanoparticle zirconium oxide (nano-ZrO2) added to heat-cured poly(methyl methacrylate) (PMMA) after thermocycling. The specimens were divided into four groups according to the ratio of nano-ZrO2 addition to heat-cured PMMA; group 1: 5% nano-ZrO2; group 2: 10% nano-ZrO2; group 3: 20% nano-ZrO2, and group 4 (control): PMMA without nano-ZrO2. A statistically significant decrease in transverse strength was observed by all additional rates of nano-ZrO2 compared with group 4 (control; P < 0.025). When hardness results were evaluated, groups 1 and 2 showed statistically higher values compared with groups 3 and 4 (P < 0.025). The surface roughness of group 3 was statistically higher than the other groups (P < 0.025), but it was within the clinically acceptable limits. As the nano-ZrO2 addition rate increased, water sorption/solubility values of the specimens also increased. Although nano-ZrO2 addition had an adverse effect on some mechanical and physical properties of heat-cured PMMA, it increased hardness values, implying that the addition of nano-ZrO2 would contribute positively to some mechanical properties of PMMA denture base material when nano-ZrO2 was homogeneously distributed in PMMA
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