1,909 research outputs found
Perancangan Suplai Tegangan Cadangan Untuk Mengantisipasi Supaya Baterai Ups Di Electric Room 5 Tidak Kehabisan Daya
Uninterruptable Power Supply (UPS) is an important component in the control system. It is useful for temporarily storing electrical energy. Energy storage is carried out in the UPS batteries. These batteries have a certain capacity according to the load requirements. UPS batteries only last an average of 2 hours if it does not get a supply voltage from the outside. Failure in the distribution of this voltage can cause exhaustion of the UPS batteries so some components in the control system can not work. To avoid this, the UPS system should get a backup voltage source. Backup voltage source is taken from an existing generator set. Making backup voltage is accompanied by a control system to ensure security in the event of transferring voltage from the main voltage source to the backup voltage. The control system used is conventional control system using the contactor. We hope it can transfer voltage from main to the backup voltage easily if there is problem with main voltage from main power.
Key words: UPS, UPS battery, backup voltage, efficiency, safety
Characterization of regular convolutions
In this paper, we present a characterization of regular convolution
Ideals in (Z⁺, ≤D)
A convolution is a mapping C of the set Z⁺ of positive integers into the set P(Z⁺) of all subsets of Z⁺ such that every member of C(n) is a divisor of n. If for any n, D(n) is the set of all positive divisors of n, then D is called the Dirichlet's convolution. It is well known that Z⁺ has the structure of a distributive lattice with respect to the division order. Corresponding to any general convolution C, one can define a binary relation ≤C on Z⁺ by 'm ≤ C n if and only if m ∈ C(n) '. A general convolution may not induce a lattice on Z⁺. However most of the convolutions induce a meet semi lattice structure on Z⁺. In this paper we consider a general meet semi lattice and study it's ideals and extend these to (Z⁺, ≤D), where D is the Dirichlet's convolution
Do Antibiotics Improve Outcomes for Patients Hospitalized with COPD Exacerbations?
EVIDENCE-BASED ANSWER
YES. Antibiotic use reduced mortality and treatment failure in patients hospitalized with acute exacerbations of chronic obstructive pulmonary disease (COPD) (strength of recommendation [SOR]: A, systematic reviews of randomized controlled trials [RCTs]).
Giving antibiotics early to hospitalized patients decreased the need for later ventilation and readmission within 30 days for exacerbation of COPD (SOR: B, a retrospective cohort study)
2,3,7,8-TETRAKLORODIBENZO-P-DIOKSIN (TCDD) MEMACU AKTIVITAS BIOSINTESIS PROTEIN DI JARINGAN PALATUM EMBRIO MENCIT
Bahan pencemar dioksin 2,3,7,8-Tetraklorodibenzo-p-dioksin (TCDD) yang diberikan
pada mencit bunting menyebabkan janin yang dihasilkan menderita cacat cleft palate,
dengan ciri bilah palatum kerdil atau bilah palatum tumbuh pendek. Telah dilakukan
penelitian untuk menguji apakah pengurangan biosintesis protein terlibat sebagai
mekanisme yang mendasari hambatan pertumbuhan bilah palatum oleh TCDD. Delapan
ekor mencit bunting dibagi ke dalam empat kelompok, masing-masing diberi TCDD
dosis 0, 5, 10, atau 20 μg/kg berat badan pada hari ke-12 kebuntingan. Besaran aktivitas
biosintesis protein jaringan palatum embrio ditentukan dengan teknik AgNOR pada
sediaan histologis irisan jaringan kraniofasial embrio usia kebuntingan hari ke-15.
Nucleolar Organizing Region (NOR) adalah tempat biogenesis ribosom di inti sel yang
jumlahnya meningkat seiring dengan peningkatan aktivitas biosintesis protein sel.
Rataan jumlah butir AgNOR sel-sel jaringan palatum yang terendah adalah 2,51±0,167
untuk perlakuan 0 μg/kg bb (kontrol), dan berturut-turut 2,87±0,146, 2,87±0,190, dan
2,88±0,160 untuk perlakuan dosis 5, 10, dan 20 μg/kg bb. Jumlah butir AgNOR pada
seluruh kelompok yang diberi TCDD lebih tinggi dibandingkan dengan jumlah butir
AgNOR pada kontrol (P < 0,05). Disimpulkan, pengurangan biosintesis protein
bukanlah mekanisme yang mendasari hambatan pertumbuhan palatum mencit oleh
TCDD. Diduga, peningkatan biosintesis protein oleh TCDD menimbulkan kekacauan
keseimbangan protein-protein faktor tumbuh di jaringan palatum dan mengakibatkan
gangguan pertumbuhan dan diferensias
Do Newton's G and Milgrom's a_0 vary with cosmological epoch ?
In the scalar tensor gravitational theories Newton's constant G_N evolves in
the expanding universe. Likewise, it has been speculated that the acceleration
scale a_0 in Milgrom's modified Newtonian dynamics (MOND) is tied to the scale
of the cosmos, and must thus evolve. With the advent of relativistic
implementations of the modified dynamics, one can address the issue of
variability of the two gravitational ''constants'' with some confidence. Using
TeVeS, the Tensor-Vector-Scalar gravitational theory, as an implementation of
MOND, we calculate the dependence of G_N and a_0 on the TeVeS parameters and
the coeval cosmological value of its scalar field, \phi_c. We find that G_N,
when expressed in atomic units, is strictly nonevolving, a result fully
consistent with recent empirical limits on the variation of G_N. By contrast,
we find that a_0 depends on \phi_c and may thus vary with cosmological epoch.
However, for the brand of TeVeS which seems most promising, a_0 variation
occurs on a timescale much longer than Hubble's, and should be imperceptible
back to redshift unity or even beyond it. This is consistent with emergent data
on the rotation curves of disk galaxies at significants redshifts.Comment: 9 pages, RevTe
Measurement of the Homogeneous Contact of a Unitary Fermi gas
By selectively probing the center of a trapped gas, we measure the local, or
homogeneous, contact of a unitary Fermi gas as a function of temperature. Tan's
contact, C, is proportional to the derivative of the energy with respect to the
interaction strength, and is thus an essential thermodynamic quantity for a gas
with short-range correlations. Theoretical predictions for the temperature
dependence of C differ substantially, especially near the superfluid
transition, Tc, where C is predicted to either sharply decrease, sharply
increase, or change very little. For T/T_F>0.4, our measurements of the
homogeneous gas contact show a gradual decrease of C with increasing
temperature, as predicted by theory. We observe a sharp decrease in C at
T/T_F=0.16, which may be due to the superfluid phase transition. While a sharp
decrease in C below Tc is predicted by some many-body theories, we find that
none of the predictions fully accounts for the data.Comment: 5 pages, including a supplementary material section (10 pages).
Rewriting of the introduction and discussion section
PACLITAXEL DISPOSITION STUDIES USING P-GP INHIBTOR & INDUCER BY SINGLE PASS INTESTINAL PERFUSION IN RATS
Objective:
The present research work aims to study the intestinal transport of Paclitaxel and to predict its human intestinal permeability and fraction absorbed using SPIP Permeability Coefficient and the effect of P-gp modulators on Paclitaxel were observed in anaesthetized rats.
Methods:
Jejunal segment was used for performing Single Pass Intestinal Perfusion. The rationale for the selection of jejenum is due to the overexpression of P-glycoprotein when compared with other segments. Drug solution (150µg/ml) in phosphate buffer saline was perfused at a flow rate of 0.2ml/min.Besides,P-gp inhibitor verapamil(200 µg/ml) and inducer Rifampicin (60mg/ml) were coperfused with Paclitaxel to detect its disposition characteristics affected by P-gp .Drug concentrations in samples were analyzed using HPLC. Stability studies were conducted to ensure the loss of Paclitaxel due to absorption.
Results:
The effective permeability value of Paclitaxel (150µg/ml) in the jejunal segment was found to be lower due to the efflux mediated by P-gp.When coperfused with verapamil its permeability significantly enhanced as it is a P-gp inhibitor and vice versa with Rifampicin which is a P-gp inducer. Subsequently the human intestinal permeability was estimated considering Peff(human) =1.04 Peff(rat)-0.0003.
Conclusion:
P-Glycoprotein mediated drug resistance is one of the serious limitations of Paclitaxel efficacy and jejunal segment is found to have major MDR expression. The Peff value of Paclitaxel was found to be increased upon the Coperfusion with verapamil and similarly reduced with Rifampicin which are inhibitors & inducers respectively indicating Paclitaxel is efficiently transported by P-gp. Hence, Paclitaxel satisfies all the prerequisites to be a P-gp substrate.
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Keywords: Paclitaxel, Intestinal permeability, Single pass intestinal perfusion, P-glycoprotein, RP-HPLC
A quest for frustration driven distortion in Y2Mo2O7
We investigated the nature of the freezing in the geometrically frustrated
Heisenberg spin-glass Y2Mo2O7 by measuring the temperature dependence of the
static internal magnetic field distribution above the spin-glass temperature,
Tg, using the muSR technique. The evolution of the field distribution cannot be
explained by changes in the spin susceptibility alone and suggests a lattice
deformation. This possibility is addressed by numerical simulations of the
Heisenberg Hamiltonian with magneto-elastic coupling at T>0.Comment: 5 pages 4 figures. Accepted for publication in PR
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