Mitigasi Bencana Pesisir: Pemberdayaan Komunitas Nelayan Sipatuo melalui Penanaman Mangrove di Kelurahan Tahoa, Kabupaten Kolaka, Sulawesi Tenggara

Wilayah pesisir sering kali menjadi sasaran bencana alam, yang dapat berdampak serius pada komunitas nelayan. Pengurangan ekosistem mangrove di pesisir dapat meningkatkan risiko banjir, erosi pantai, dan gelombang tinggi. Oleh karena itu, dalam program kegiatan Kosabangsa (Kolaborasi Sosial Membangun Masyarakat), pengabdian masyarakat ini bertujuan untuk membantu komunitas nelayan Sipatuo di Kelurahan Tahoa, Sulawesi Tenggara dalam menghadapi masalah bencana di wilayah pesisir yang merupakan tempat bermukim mereka. Kegiatan penanaman pohon mangrove dilakukan sebagai cara untuk melindungi pantai dan meningkatkan pemahaman komunitas tentang pentingnya pohon mangrove. Masyarakat dilibatkan dalam sosialisasi dan penanaman mangrove. Hasilnya sangat positif, dengan pemahaman masyarakat meningkat sekitar 18%, dan hampir semua orang ikut berpartisipasi. Ini menunjukkan bahwa kegiatan ini sangat efektif dalam memberikan pengetahuan kepada Masyarakat pesisir. Kegiatan pengabdian ini penting dalam upaya pelestarian lingkungan pesisir di wilayah Sulawesi Tenggara. Perlu diadakan penelitian  untuk melihat dampak jangka panjang dari upaya mitigasi bencana pesisir dan bagaimana pelestarian mangrove dapat membantu komunitas dalam menghadapi bencana pesisir.Wilayah pesisir sering kali menjadi sasaran bencana alam, yang dapat berdampak serius pada komunitas nelayan. Pengurangan ekosistem mangrove di pesisir dapat meningkatkan risiko banjir, erosi pantai, dan gelombang tinggi. Oleh karena itu, dalam kerangka program Kosabangsa (Kolaborasi Sosial Membangun Masyarakat), pengabdian masyarakat ini bertujuan untuk membantu komunitas nelayan Sipatuo di Kelurahan Tahoa, Sulawesi Tenggara dalam menghadapi masalah bencana di pesisir mereka. Kegiatan penanaman pohon mangrove dilakukan sebagai cara untuk melindungi pantai dan meningkatkan pemahaman komunitas tentang pentingnya pohon mangrove. Masyarakat dilibatkan dalam sosialisasi dan penanaman mangrove. Hasilnya sangat positif, dengan pemahaman masyarakat meningkat sekitar 18%, dan hampir semua orang ikut berpartisipasi. Ini menunjukkan bahwa model pembelajaran melalui praktik nyata sangat efektif. Pengabdian ini penting dalam upaya pelestarian lingkungan pesisir. Perlu penelitian lanjutan untuk melihat dampak jangka panjang dari upaya ini dan bagaimana pelestarian mangrove dapat membantu komunitas dalam menghadapi bencana pesisir

Molecular Interactions between Prions as Seeds and Recombinant Prion Proteins as Substrates Resemble the Biological Interspecies Barrier In Vitro

Prion diseases like Creutzfeldt-Jakob disease in humans, Scrapie in sheep or bovine spongiform encephalopathy are fatal neurodegenerative diseases, which can be of sporadic, genetic, or infectious origin. Prion diseases are transmissible between different species, however, with a variable species barrier. The key event of prion amplification is the conversion of the cellular isoform of the prion protein (PrPC) into the pathogenic isoform (PrPSc). We developed a sodiumdodecylsulfate-based PrP conversion system that induces amyloid fibril formation from soluble α-helical structured recombinant PrP (recPrP). This approach was extended applying pre-purified PrPSc as seeds which accelerate fibrillization of recPrP. In the present study we investigated the interspecies coherence of prion disease. Therefore we used PrPSc from different species like Syrian hamster, cattle, mouse and sheep and seeded fibrillization of recPrP from the same or other species to mimic in vitro the natural species barrier. We could show that the in vitro system of seeded fibrillization is in accordance with what is known from the naturally occurring species barriers

Detection of Prion Protein Particles in Blood Plasma of Scrapie Infected Sheep

Prion diseases are transmissible neurodegenerative diseases affecting humans and animals. The agent of the disease is the prion consisting mainly, if not solely, of a misfolded and aggregated isoform of the host-encoded prion protein (PrP). Transmission of prions can occur naturally but also accidentally, e.g. by blood transfusion, which has raised serious concerns about blood product safety and emphasized the need for a reliable diagnostic test. In this report we present a method based on surface-FIDA (fluorescence intensity distribution analysis), that exploits the high state of molecular aggregation of PrP as an unequivocal diagnostic marker of the disease, and show that it can detect infection in blood. To prepare PrP aggregates from blood plasma we introduced a detergent and lipase treatment to separate PrP from blood lipophilic components. Prion protein aggregates were subsequently precipitated by phosphotungstic acid, immobilized on a glass surface by covalently bound capture antibodies, and finally labeled with fluorescent antibody probes. Individual PrP aggregates were visualized by laser scanning microscopy where signal intensity was proportional to aggregate size. After signal processing to remove the background from low fluorescence particles, fluorescence intensities of all remaining PrP particles were summed. We detected PrP aggregates in plasma samples from six out of ten scrapie-positive sheep with no false positives from uninfected sheep. Applying simultaneous intensity and size discrimination, ten out of ten samples from scrapie sheep could be differentiated from uninfected sheep. The implications for ante mortem diagnosis of prion diseases are discussed

Extraction of Semantic Representations from Syntactic CMU Link Grammar linkages

A method for generating a Discourse Representation Structure (DRS) semantic representation from the output of the Carnegie Mellon University (CMU) link grammar parser is presented. The techniques used in extracting information from the link grammar representation and construction of the DRS are detailed. The system is a major component of the EU funded ViSiCAST (Virtual Signing: Capture, Animation, Storage and Transmission) project 1 for presenting English text as sign language presentations

Grammar Development for Sign Language Avatar-Based Synthesis

Research in oSign Lan44w (SL) gen ration from En9H4k text at theUn4PP sity of East An74Z has inw894; SL grammar developmen to support SL synI; sisan d visual realisation byan avatar (virtual sign94 (Ken away, 2001). To thaten SLs must be treated as gen inn atural lan7Z;Hw worthy of academic studyin their own right. They are then ative lanw974I of the pre-linN788H deaf whose familiarity with the geographically promin99 oral lanw9I7 is that of a secon lan79IZ learn r. Thus for the prelin99w ly deaf written text is much less useful than iscommonw thought. We illustrate the utility of SL research for SLsyn; esis by a preliminH7 con ideration of plurality an placemen within a grammar for BritishSign Lan88w (BSL). 1 Introducti DurinH the last half cenw ry sign lan477wN9 have been recognZkHw as gen974w min9 ity lan;ZIHwN which coexist with majority lanZZ;wN9 (Neidle, Kegl, MacLaughlina an9 Bahan & Lee, 2000) an7 which are the ne ive lanI7Z8wN for man; deaf people. It is a common misapprehen sion that sign lanw77978 are restricted to communN9I78kw in formation through the form an9 motion of the han s. However, sign lan48;wN inn48; the simultan eous use of mankHk an n n an9H9 componNk4H in signk8 communNk4HZ no Nonmank8I features are comprised of the posture of the upper torso, the orien tation of the head an8 facial expressionI Man al features have been often been decomposed as hanZ98wNk;; han7 orien ation4 han positionanH motion (Stokoe, 1978; Brien7 1992; SuttonkkPwNk8 & Woll, 1999). The Hamburg Notation System (HamNoSys) (Prillwitz, Leven9 Zien9 t. Han479 & Hen in9 1989; Han7H; 2004) is an established phon4 ic tran cription system for sign lanZZwNkk which comprises more than 200 icon ically motivated symbols to describe the manPwN annPwNkH84;wnn tures of sign7 Provi..

Intérêt du scanner hélical dans l'imagerie de la colique néphrétique (étude prospective comparative avec l'urographie intra veineuse)

AMIENS-BU Santé (800212102) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Three or less? Decision making for or against selective reduction and psychological outcome in forty women with a triplet pregnancy

Objectives The aim of the study was to investigate decision making for or against multifetal pregnancy reduction (MFPR) and psychological outcome in women with a triplet pregnancy. Methods We investigated medical and sociodemographic variables and characteristics of the decision process for or against MFPR in forty women with triplet pregnancies who had either undergone MFPR (MFPR-group: N = 10) or had delivered triplets (triplet-group: N = 30). Moreover, emotional experiences of the reduction procedure were assessed. Psychological outcome was measured using the Beck Depression inventory (BDI) and the 36-Item Short Form Health Survey (SF-36). Results Women of the MFPR-group had a higher gestational age at delivery (p = 0.001), shorter NICU stay (p = 0.001), higher educational level (p = 0.010), more frequently utilized psychological counseling during the decision process (p = 0.016), rated their gynecologist as more helpful for the decision (p = 0.045), required more time for their decision (p = 0.016), and were more likely to be in paid employment at follow-up (p = 0.041) than women of the triplet-group. MFPR was experienced as stressful (90%) or terrifying (10%). At 3.2 (±2.2) years after delivery, the vast majority of women in both groups were free from clinically relevant depression. Conclusions MFPR, though associated with emotional distress related to the procedure, results in a satisfactory psychological outcome in the majority of women. The decision for or against MFPR may be related to sociodemographic (such as educational) variables, which further supports the concept of framing in medical decision making. Having triplets most probably is associated with multiple (e.g. social or economic) consequences that may remain poorly investigated

Translation of English Text to a DRS-based, Sign Language Oriented Semantic Representation

Une vue d'ensemble de l'architecture de la partie linguistique d'un systeme de traduction de texte Anglais en langage de signes est presentee. Nous nous concentrons sur la traduction du texte en langue naturelle vers une representation semantique pour l'aide a la traduction gestuelle. Nous rapportons nos progres actuels dans l'application de techniques syntaxiques, semantiques et contextuelles de traitement du langage naturel pour la generation de la representation semantique. Par ailleurs nous prenons en compte la necessite de fournir, a l'etape d'analyse du texte, des moyens d'intervention manuelle pour ameliorer la qualite de la traduction lorsque les techniques automatiques s'averent insuffisament precises