Managing of solid waste on construction site

Construction solid waste is a waste in solid form which is defined as useless or unwanted. It generated from building construction, demolition and refurbishment works. It has become as one of major environmental problems faced by the most municipalities.This paper based on study that has been conducted which involves types of solid wastes and factors that contribute to the waste on construction site. This study also focused on method used in managing solid waste on site. Two (2) methods have been used to achieve the objectives of this study which are questionnaire and interview. 34 respondents who are from construction company and local authorities in Pahang gave their feedback by answering the questionnaires. Data from questionnaire have been analyzed using average index (A!). Interview through site visit is carried out in Pekan, Pahang. It is done to get further information about methods used in managing waste on site. In conclusion, types of solid waste, factors contribute to waste on site and methods of managing solid waste have been identified. This study found that there are 8 types of construction waste on site such as concrete, asphalt, wood or timber, glass, plastic, metal or steel, roofing and brick or block. There are several factors contribute to waste on site such as lack of recycling facilities within the study region, mishandling, weather, inadequate storage, lack of communication between leader and worker, design changes,vandalism, ordering error, role of project manager and low quality material. The study result also shows the popular method choose by respondent to handle the solid waste which is dispose it and this is followed by reducing, recycling and reuse method

The Cytotoxicity of Eupatorium cannabinum Methanolic Extract in a Human Breast Adenocarcinoma Cell Line (MCF-7)

Introduction: Eupatorium cannabinum belonging to Asteraceae family is commonly known as hemp agrimony. E. cannabinum is used to treat headache, hepatitis, diarrhea, diabetes mellitus and hypertension. Considerable researches have been indicated various biological activities of E. cannabinum such as cytotoxic, antioxidant, antimicrobial, anti-inflammatory, immunological and hepatoprotective activities. Since the cytotoxic activity of E. cannabinum on human breast adenocarcinoma cell line (MCF-7) have not been reported, the current study was conducted to evaluate the cytotoxicity of the total extract of E. cannabinum on MCF-7 cells. Methods and Results: MCF-7 cell line was treated with different concentrations (3.125 to 100 μg/mL) of the E. cannabinum total (methanolic) extract. After 48 hrs, the cytotoxic activity was assessed through MTT (3-[4, 5-Dimethylthiazol-2-Yl]-2, 5-diphenyltetrazolium bromide) assay. The methanolic extract demonstrated cytotoxicity against MCF-7 cell line with IC50 (the concentrationthat inhibited cell growth by 50%) value of 69.5 μg/mL. Conclusions: The methanolic extract of E. cannabinum showed considerable cytotoxic activity. Evaluating the apoptosis induction ability of E. cannabinum could be suggested for further studies

Cytotoxicity of Two Gypsophila Species to Human Breast Adenocarcinoma (MCF-7)

Introduction: Cancer is known as the second cause of death worldwide which results in serious problems in human life. It is developed by uncontrolled growth of a cell or a group of cells. Caryophyllaceae is a large family which has been reported to possess cytotoxic species and in the present study, the cytotoxic activity of two plants from this family has been evaluated. Methods and Results: Dried powder of Gypsophila bicolor (Freyn & Sint.) Grossh and Gypsophila ruscifolia Boiss. aerial parts were extracted with methanol 80% by maceration method (10 g). For fractionation, 30 g of the dried powder of both species was macerated with petroleum ether at room temperature. After 24 hours, the mixture was filtered and the plant residues were extracted with chloroform and methanol successively through the same process. Then they were concentrated using a rotary evaporator apparatus. The cytotoxic activity was evaluated against MCF-7 (human breast adenocarcinoma), A-549 (non-small cell lung carcinoma) and AGO-1522 (human fibroblast) cell lines using MTT assay. The chloroform fractions of both Gypsophila species showed cytotoxic effects against MCF-7 cells with IC50 value <100 μg/mL. None of the extracts or fractions demonstrated cytotoxicity to A-549 or AGO-1522 cells up to the tested concentrations. Conclusions: The selective toxicity of the chloroform fractions of the species only to the MCF-7 cell line suggested that Gypsophila bicolor and G. ruscifolia could be proper candidates for further studies in the field of cancer researches

Bi-Level Operation Scheduling of Distribution Systems with Multi-Microgrids Considering Uncertainties

A bi-level operation scheduling of distribution system operator (DSO) and multi-microgrids (MMGs) considering both the wholesale market and retail market is presented in this paper. To this end, the upper-level optimization problem minimizes the total costs from DSO’s point of view, while the profits of microgrids (MGs) are maximized in the lower-level optimization problem. Besides, a scenario-based stochastic programming framework using the heuristic moment matching (HMM) method is developed to tackle the uncertain nature of the problem. In this regard, the HMM technique is employed to model the scenario matrix with a reduced number of scenarios, which is effectively suitable to achieve the correlations among uncertainties. In order to solve the proposed non-linear bi-level model, Karush–Kuhn–Tucker (KKT) optimality conditions and linearization techniques are employed to transform the bi-level problem into a single-level mixed-integer linear programming (MILP) optimization problem. The effectiveness of the proposed model is demonstrated on a real-test MMG system

Effects of Maternal Separation on Nicotine-Induced Conditioned Place Preference and Later Spatial Learning and Memory Function in Adolescent Male Rats

Background: Disturbances in maternal care have been associated with increased risk for drug abuse later in life. However, there has been little investigation of the effects of maternal separation (MS), a model of early life stress, on nicotine dependence, specifically during adolescence. In the present study, we aimed to investigate the effect of MS on nicotine-conditioned place preference (CPP) in adolescent male rats. We also examined the impact of nicotine on spatial learning and memory impairments induced by MS.Methods: Rat pups were exposed to daily MS for 15 (MS15) or 180 (MS180) minutes during the first 2 weeks of life or reared under normal animal facility rearing (AFR) conditions. In postnatal day (PND) 28-34, they were conditioned with nicotine [0.6 mg/kg, subcutaneously (SC)] or saline and tested for preference over a period of 6 conditioning trials. Morris water maze (MWM) testing was performed to assess spatial cognitive function.Findings: The MS procedure used in our study failed to affect nicotine reward as measured by CPP in the adolescent male rats. Notably, significant spatial learning deficit was seen in the MS180 rats compared to those in the AFR and MS15 groups and nicotine administration modified the MS-induced learning defect in adolescent male rats.Conclusion: In conclusion, although MS revealed no influence on the sensitivity to the nicotine's reinforcing effects in adolescent male rats, the simultaneous effect of MS on learning performance may be altered by nicotine intake