70 research outputs found

    Chaos and the continuum limit in nonneutral plasmas and charged particle beams

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    This paper examines discreteness effects in nearly collisionless N-body systems of charged particles interacting via an unscreened r^-2 force, allowing for bulk potentials admitting both regular and chaotic orbits. Both for ensembles and individual orbits, as N increases there is a smooth convergence towards a continuum limit. Discreteness effects are well modeled by Gaussian white noise with relaxation time t_R = const * (N/log L)t_D, with L the Coulomb logarithm and t_D the dynamical time scale. Discreteness effects accelerate emittance growth for initially localised clumps. However, even allowing for discreteness effects one can distinguish between orbits which, in the continuum limit, feel a regular potential, so that emittance grows as a power law in time, and chaotic orbits, where emittance grows exponentially. For sufficiently large N, one can distinguish two different `kinds' of chaos. Short range microchaos, associated with close encounters between charges, is a generic feature, yielding large positive Lyapunov exponents X_N which do not decrease with increasing N even if the bulk potential is integrable. Alternatively, there is the possibility of larger scale macrochaos, characterised by smaller Lyapunov exponents X_S, which is present only if the bulk potential is chaotic. Conventional computations of Lyapunov exponents probe X_N, leading to the oxymoronic conclusion that N-body orbits which look nearly regular and have sharply peaked Fourier spectra are `very chaotic.' However, the `range' of the microchaos, set by the typical interparticle spacing, decreases as N increases, so that, for large N, this microchaos, albeit very strong, is largely irrelevant macroscopically. A more careful numerical analysis allows one to estimate both X_N and X_S.Comment: 13 pages plus 17 figure

    Living knowledge of the healing plants: Ethno-phytotherapy in the Chepang communities from the Mid-Hills of Nepal

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    Contribution of indigenous knowledge in developing more effective drugs with minimum or no side effects helped to realise importance of study of indigenous remedies and the conservation of biological resources. This study analysed indigenous knowledge regarding medicinal plants use among the Chepang communities from ward number 3 and 4 of Shaktikhor Village Development Committee located in the central mid hills of Nepal. Data were collected in a one-year period and included interviews with traditional healers and elders. Chepangs are rich in knowledge regarding use of different plants and were using a total 219 plant parts from 115 species including one mushroom (belonging 55 families) for medicinal uses. Out of these, 75 species had 118 different new medicinal uses and 18 of them were not reported in any previous documents from Nepal as medicinal plants. Spiritual belief, economy and limitation of alternative health facilities were cause of continuity of people's dependency on traditional healers. Change in socio-economic activities not only threatened traditional knowledge but also resource base of the area. Enforcement of local institution in management of forest resources and legitimating traditional knowledge and practices could help to preserve indigenous knowledge

    The Gac-Rsm and SadB Signal Transduction Pathways Converge on AlgU to Downregulate Motility in Pseudomonas fluorescens

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    Flagella mediated motility in Pseudomonas fluorescens F113 is tightly regulated. We have previously shown that motility is repressed by the GacA/GacS system and by SadB through downregulation of the fleQ gene, encoding the master regulator of the synthesis of flagellar components, including the flagellin FliC. Here we show that both regulatory pathways converge in the regulation of transcription and possibly translation of the algU gene, which encodes a sigma factor. AlgU is required for multiple functions, including the expression of the amrZ gene which encodes a transcriptional repressor of fleQ. Gac regulation of algU occurs during exponential growth and is exerted through the RNA binding proteins RsmA and RsmE but not RsmI. RNA immunoprecipitation assays have shown that the RsmA protein binds to a polycistronic mRNA encoding algU, mucA, mucB and mucD, resulting in lower levels of algU. We propose a model for repression of the synthesis of the flagellar apparatus linking extracellular and intracellular signalling with the levels of AlgU and a new physiological role for the Gac system in the downregulation of flagella biosynthesis during exponential growth

    Ethnobotany in the Nepal Himalaya

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    <p>Abstract</p> <p>Background</p> <p>Indigenous knowledge has become recognized worldwide not only because of its intrinsic value but also because it has a potential instrumental value to science and conservation. In Nepal, the indigenous knowledge of useful and medicinal plants has roots in the remote past.</p> <p>Methods</p> <p>The present study reviews the indigenous knowledge and use of plant resources of the Nepal Himalayas along the altitudinal and longitudinal gradient. A total of 264 studies focusing on ethnobotany, ethnomedicine and diversity of medicinal and aromatic plants, carried out between 1979 and 2006 were consulted for the present analysis. In order to cross check and verify the data, seven districts of west Nepal were visited in four field campaigns.</p> <p>Results</p> <p>In contrast to an average of 21–28% ethnobotanically/ethnomedicinally important plants reported for Nepal, the present study found that up to about 55% of the flora of the study region had medicinal value. This indicates a vast amount of undocumented knowledge about important plant species that needs to be explored and documented. The richness of medicinal plants decreased with increasing altitude but the percentage of plants used as medicine steadily increased with increasing altitude. This was due to preferences given to herbal remedies in high altitude areas and a combination of having no alternative choices, poverty and trust in the effectiveness of folklore herbal remedies.</p> <p>Conclusion</p> <p>Indigenous knowledge systems are culturally valued and scientifically important. Strengthening the wise use and conservation of indigenous knowledge of useful plants may benefit and improve the living standard of poor people.</p

    Introduction: Human ecology in the Himalaya

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    Knowledge of human adaptation in the Himalayas has developed more slowly than that for other world mountain systems. At the same time, the opening of the region to research has focused attention toward description in a “natural history” mode until quite recently. Where these studies have addressed issues of adaptation they have tended to do so more as a heuristic tool rather than in terms of contributing to the development of adaptive perspectives from a uniquely Himalayan vantage point. The contributions to this special issue suggest some of Himalayan cultural ecology's new themes as it more directly assumes a truly processual approach that incorporates the individual and domestic dimensions of adaptation within historical and social contexts .Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/44482/1/10745_2004_Article_BF00889710.pd

    Observation and correction of instabilities in circular accelerators

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    Shaping of proton distribution for raising the space-charge of the CERN PS Booster

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    The intensity of the PS Booster is limited by space-charge defocusing forces which create a spread in the betatron tunes of up to Delta G approximately=0.5. Shaping of the transverse and longitudinal distributions was used for accommodating more particles in a given working area and enabled the Booster to accelerate 2*10/sup 13/ protons per pulse, twice the design intensity. Modifying the RF potential well by an experimental second harmonic cavity yields beam intensities and densities well beyond the present performance. The corresponding PSB experiments and improvements are described and an outlook on future developments is given. (14 refs)

    Verfahren zur Herstellung von optisch aktiven ß-Aminocarbonsäuren aus racemischen N-acetylierten ß-Aminocarbonsäuren

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    Gröger H, Trauthwein H, Drauz K, Buchholz S, Sacherer C, Werner H. Verfahren zur Herstellung von optisch aktiven ß-Aminocarbonsäuren aus racemischen N-acetylierten ß-Aminocarbonsäuren. 2003
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