397 research outputs found

    Результаты симультанных операций у пациентов с атеросклеротическим поражением сонных и коронарных артерий

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    СОННЫЕ АРТЕРИИАТЕРОСКЛЕРОЗАРТЕРИОСКЛЕРОЗКОРОНАРНЫХ АРТЕРИЙ СТЕНОЗКАРОТИДНАЯ ЭНДАРТЕРЭКТОМИЯСОННОЙ АРТЕРИИ ЭНДАРТЕРЭКТОМИЯСТЕНОКАРДИЯАОРТОКОРОНАРНОЕ ШУНТИРОВАНИЕКОРОНАРНОЙ АРТЕРИИ ШУНТИРОВАНИ

    Effects of resistance training performed to repetition failure or non-failure on muscular strength and hypertrophy: A systematic review and meta-analysis

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    PURPOSE: We aimed to perform a systematic review and meta-analysis of the effects of training to muscle failure or non-failure on muscular strength and hypertrophy. METHODS: Meta-analyses of effect sizes (ESs) explored the effects of training to failure vs. non-failure on strength and hypertrophy. Subgroup meta-analyses explored potential moderating effects of variables such as training status (trained vs. untrained), training volume (volume equated vs. volume non-equated), body region (upper vs. lower), exercise selection (multi- vs. single-joint exercises (only for strength)), and study design (independent vs. dependent groups). RESULTS: Fifteen studies were included in the review. All studies included young adults as participants. Meta-analysis indicated no significant difference between the training conditions for muscular strength (ES = –0.09, 95% confidence interval (95%CI): –0.22 to 0.05) and for hypertrophy (ES = 0.22, 95%CI: –0.11 to 0.55). Subgroup analyses that stratified the studies according to body region, exercise selection, or study design showed no significant differences between training conditions. In studies that did not equate training volume between the groups, the analysis showed significant favoring of non-failure training on strength gains (ES = –0.32, 95%CI: –0.57 to –0.07). In the subgroup analysis for resistance-trained individuals, the analysis showed a significant effect of training to failure for muscle hypertrophy (ES = 0.15, 95%CI: 0.03–0.26). CONCLUSION: Training to muscle failure does not seem to be required for gains in strength and muscle size. However, training in this manner does not seem to have detrimental effects on these adaptations, either. More studies should be conducted among older adults and highly trained individuals to improve the generalizability of these findings

    Transformation kinetics of alloys under non-isothermal conditions

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    The overall solid-to-solid phase transformation kinetics under non-isothermal conditions has been modeled by means of a differential equation method. The method requires provisions for expressions of the fraction of the transformed phase in equilibrium condition and the relaxation time for transition as functions of temperature. The thermal history is an input to the model. We have used the method to calculate the time/temperature variation of the volume fraction of the favored phase in the alpha-to-beta transition in a zirconium alloy under heating and cooling, in agreement with experimental results. We also present a formulation that accounts for both additive and non-additive phase transformation processes. Moreover, a method based on the concept of path integral, which considers all the possible paths in thermal histories to reach the final state, is suggested.Comment: 16 pages, 7 figures. To appear in Modelling Simul. Mater. Sci. En

    Kainic acid alters the metabolism of Met5-enkephalin and the level of dynorphin A in the rat hippocampus

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    Male Fischer-344 rats were given a single intrastriatal injection of kainic acid (KA; 1 microgram/rat), which caused recurrent motor seizures lasting 3-6 hr. During the convulsive period, native Met5-enkephalin-like (ME-LI) and dynorphin A (1-8)-like (DYN-LI) immunoreactivities in hippocampus decreased by 31 and 63%, respectively. By 24 hr after dosing, the hippocampal opioid peptides had returned to control levels, and by 48 hr ME-LI had increased 270% and DYN-LI 150%. Immunocytochemical analysis revealed that ME-LI and Leu5-enkephalin-like (LE-LI) immunostaining in the mossy fibers of dentate granule cells and the perforant-temporoammonic pathway had decreased visibly by 6 hr and had increased markedly by 48 hr following KA. A visible decrease in DYN-LI in mossy fiber axons within 6 hr was followed by a substantial increase by 48 hr. To determine whether the increases in hippocampal ME-LI reflected changes in ME biosynthesis, levels of mRNA coding for preproenkephalin (mRNAenk) and cryptic ME-LI cleaved by enzyme digestion from preproenkephalin were measured. Following the convulsive period (6 hr), mRNAenk was 400% of control, and by 24 hr, cryptic ME-LI was 300% of control. Increases in native and cryptic ME-LI and in mRNAenk were also noted in entorhinal cortex, but not in hypothalamus or uninjected striatum. Our data suggest that KA-induced seizures cause an increase in ME release, followed by a compensatory increase in ME biosynthesis in the hippocampus and entorhinal cortex

    The Lantern Vol. 62, No. 1, December 1994

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    • Hollow • A Little Knowledge is Dangerous • My Old Block • Life • The Natural Born Fool • Oracle • Formation of a Triangle • Marie on the Beach • The Tweed Derby • Tripping • In Vitro • The Character • Coming Home for Christmas • Unkempt • Too Much • Reimertanti-Ode • Seeds • Secrethttps://digitalcommons.ursinus.edu/lantern/1145/thumbnail.jp

    The contribution of inherited genotype to breast cancer

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    The etiology of breast cancer is complex, and is likely to involve the actions of genes at multiple levels along the multistage carcinogenesis process. These inherited genotypes include those that affect the propensity to be exposed to breast carcinogens, and those associated with breast tumorigenesis directly. In addition, inherited genotypes may influence response to breast cancer chemoprevention and treatment. Studies relating inherited genotypes with breast cancer incidence and mortality should consider a broader spectrum of genes and their potential roles in multistage carcinogenesis than have been typically evaluated to date. Understanding the role of inherited genotype at different stages of carcinogenesis could improve our understanding of cancer biology, may identify specific exposures or events that correlate with carcinogenesis, or target relevant biochemical pathways for the development of preventive or therapeutic interventions

    Thermal remote sensing from Airborne Hyperspectral Scanner data in the framework of the SPARC and SEN2FLEX projects: an overview

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    The AHS (Airborne Hyperspectral Scanner) instrument has 80 spectral bands covering the visible and near infrared (VNIR), short wave infrared (SWIR), mid infrared (MIR) and thermal infrared (TIR) spectral range. The instrument is operated by Instituto Nacional de Técnica Aerospacial (INTA), and it has been involved in several field campaigns since 2004. <br><br> This paper presents an overview of the work performed with the AHS thermal imagery provided in the framework of the SPARC and SEN2FLEX campaigns, carried out respectively in 2004 and 2005 over an agricultural area in Spain. The data collected in both campaigns allowed for the first time the development and testing of algorithms for land surface temperature and emissivity retrieval as well as the estimation of evapotranspiration from AHS data. Errors were found to be around 1.5 K for land surface temperature and 1 mm/day for evapotranspiration
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